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| Item Type: | Article |
|---|---|
| Title: | Expression, purification and preliminary X-ray crystallographic analysis of the chicken MHC class I molecule YF1*7.1 |
| Creators Name: | Hee, C.S., Gao, S., Miller, M.M., Goto, R.M., Ziegler, A., Daumke, O. and Uchanska-Ziegler, B. |
| Abstract: | YF1*7.1 is an allele of a polymorphic major histocompatibility complex (MHC) class I-like locus within the chicken Y gene complex. With the aim of understanding the possible role of the YF1*7.1 molecule in antigen presentation, the complex of YF1*7.1 heavy chain and beta(2)-microglobulin was reconstituted and purified without a peptide. Crystals diffracted synchrotron radiation to 1.32 A resolution and belonged to the monoclinic space group P2(1). The phase problem was solved by molecular replacement. A detailed examination of the structure may provide insight into the type of ligand that could be bound by the YF1*7.1 molecule. |
| Keywords: | YF1*7.1, Chicken Rfp-Y, MHC Class I Antigens, X-Ray Crystallography, Histocompatibility Antigens Class I, beta 2-Microglobulin, Animals, Chickens |
| Source: | Acta Crystallographica Section F |
| ISSN: | 1744-3091 |
| Publisher: | International Union of Crystallography |
| Volume: | 65 |
| Number: | Pt 4 |
| Page Range: | 422-425 |
| Date: | 1 April 2009 |
| Additional Information: | Erratum in: Acta Crystallographica Section F 66(Pt.2): 214 |
| Official Publication: | https://doi.org/10.1107/S1744309109009026 |
| PubMed: | View item in PubMed |
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