Item Type: | Article |
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Title: | Upregulation of myocardial estrogen receptors in human aortic stenosis |
Creators Name: | Nordmeyer, J., Eder, S., Mahmoodzadeh, S., Martus, P., Fielitz, J., Bass, J., Bethke, N., Zurbruegg, H.R., Pregla, R., Hetzer, R. and Regitz-Zagrosek, V. |
Abstract: | Estrogen receptor (ER)-mediated effects have been associated with the modulation of myocardial hypertrophy in animal models and in humans, but ER expression in the human heart and its relation to hypertrophy-mediated gene expression have not yet been analyzed. We therefore investigated sex- and disease-dependent alterations of myocardial ER expression in human aortic stenosis together with the expression of hypertrophy-related genes. |
Keywords: | Aortic Valve Stenosis, Estrogen Receptors, Hypertrophy |
Source: | Circulation |
ISSN: | 0009-7322 |
Publisher: | American Heart Association |
Volume: | 110 |
Number: | 20 |
Page Range: | 3270-3275 |
Date: | 16 November 2004 |
Official Publication: | https://doi.org/10.1161/01.CIR.0000147610.41984.E8 |
PubMed: | View item in PubMed |
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