Item Type: | Review |
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Title: | Promoting developmental transcription |
Creators Name: | Ohler, U. and Wassarman, D.A. |
Abstract: | Animal growth and development depend on the precise control of gene expression at the level of transcription. A central role in the regulation of developmental transcription is attributed to transcription factors that bind DNA enhancer elements, which are often located far from gene transcription start sites. Here, we review recent studies that have uncovered significant regulatory functions in developmental transcription for the TFIID basal transcription factors and for the DNA core promoter elements that are located close to transcription start sites. |
Keywords: | Biological Models, Developmental Gene Expression Regulation, Genetic Promoter Regions, Genetic Transcription, Transcription Factor TFIID, Transcription Initiation Site, Animals |
Source: | Development |
ISSN: | 0950-1991 |
Publisher: | Company of Biologists |
Volume: | 137 |
Number: | 1 |
Page Range: | 15-26 |
Date: | January 2010 |
Official Publication: | https://doi.org/10.1242/dev.035493 |
PubMed: | View item in PubMed |
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