Item Type: | Article |
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Title: | Genome function and nuclear architecture: from gene expression to nanoscience |
Creators Name: | O'Brien, T.P., Bult, C.J., Cremer, C., Grunze, M., Knowles, B.B., Langowski, J., McNally, J., Pederson, T., Politz, J.C., Pombo, A., Schmahl, G., Spatz, J.P. and van Driel, R. |
Abstract: | Biophysical, chemical, and nanoscience approaches to the study of nuclear structure and activity have been developing recently and hold considerable promise. A selection of fundamental problems in genome organization and function are reviewed and discussed in the context of these new perspectives and approaches. Advancing these concepts will require coordinated networks of physicists, chemists, and materials scientists collaborating with cell, developmental, and genome biologists. |
Keywords: | Cell Nucleus, Computational Biology, Gene Expression Regulation, Genome, Nanotechnology, Animals |
Source: | Genome Research |
ISSN: | 1088-9051 |
Publisher: | Cold Spring Harbor Laboratory Press |
Volume: | 13 |
Number: | 6A |
Page Range: | 1029-1041 |
Date: | June 2003 |
Official Publication: | https://doi.org/10.1101/gr.946403 |
PubMed: | View item in PubMed |
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