![[feed]](/style/images/feed-icon-14x14.png){kind=icon}
Tools
Tools
Preview |
PDF (Publisher's version)
- Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
622kB |
| Item Type: | Article |
|---|---|
| Title: | Monitoring renal hemodynamics and oxygenation by invasive probes: experimental protocol |
| Creators Name: | Cantow, K., Ladwig-Wiegard, M., Flemming, B., Pohlmann, A., Niendorf, T. and Seeliger, E. |
| Abstract: | Renal tissue hypoperfusion and hypoxia are early key elements in the pathophysiology of acute kidney injury of various origins, and may also promote progression from acute injury to chronic kidney disease. Here we describe methods to study control of renal hemodynamics and tissue oxygenation by means of invasive probes in anesthetized rats. Step-by-step protocols are provided for two setups, one for experiments in laboratories for integrative physiology and the other for experiments within small-animal magnetic resonance scanners.This publication is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This experimental protocol chapter is complemented by a separate chapter describing the basic concepts of quantitatively assessing renal perfusion and oxygenation with invasive probes. |
| Keywords: | Renal Hemodynamics and Oxygenation, In Vivo Methods, Magnetic Resonance Imaging (MRI), Animals, Rats |
| Source: | Methods in Molecular Biology |
| Series Name: | Methods in Molecular Biology |
| Title of Book: | Preclinical MRI of the kidney : methods and protocols |
| ISSN: | 1064-3745 |
| ISBN: | 978-1-0716-0977-4 |
| Publisher: | Springer / Humana Press |
| Volume: | 2216 |
| Page Range: | 327-347 |
| Date: | 2021 |
| Official Publication: | https://doi.org/10.1007/978-1-0716-0978-1_19 |
| PubMed: | View item in PubMed |
| Related to: |
Repository Staff Only: item control page
