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Item Type: | Review |
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Title: | Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective] |
Creators Name: | Faustino Martins, J.M., Nguyen, L.V.N. and Gouti, M. |
Abstract: | Organoids are miniature, organ-like structures derived from stem cells. While techniques for developing organoids for different tissues have advanced in the past decade, it has remained a challenge to simultaneously grow two different tissues into a single functional organoid. We have recently developed a 3D neuromuscular organoid that allows the simultaneous generation of spinal neurons and skeletal muscles. Here we discuss their future applications in modeling neuromuscular disorders. |
Source: | BIOspektrum |
ISSN: | 0947-0867 |
Publisher: | Springer / Spektrum Akademischer Verlag |
Volume: | 27 |
Number: | 2 |
Page Range: | 135-138 |
Date: | March 2021 |
Official Publication: | https://doi.org/10.1007/s12268-021-1553-0 |
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