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Jumping retroviruses nudge TADs apart

Item Type:Editorial
Title:Jumping retroviruses nudge TADs apart
Creators Name:Robson, M.I. and Mundlos, S.
Abstract:Far from being junk DNA, the pervasive retrotransposons that populate the genome have a powerful capacity to influence genes and chromatin. A new study demonstrates how the transcription of one such element, HERV-H, can modify the higher-order 3D structure of chromatin during early primate development.
Keywords:Epigenomics, Functional Genomics, Gene Regulation, Stem Cells, Animals
Source:Nature Genetics
ISSN:1061-4036
Publisher:Nature Publishing Group
Volume:51
Number:9
Page Range:1304-1305
Date:September 2019
Official Publication:https://doi.org/10.1038/s41588-019-0491-y
PubMed:View item in PubMed

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