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BLN protein induces cardiac hypertrophy and failure

Item Type:Article
Title:BLN protein induces cardiac hypertrophy and failure
Creators Name:Sperling, S.R.
Abstract:BBLN, a protein with predominantly uncharted functions, serves as an instigator of CAMK2D autophosphorylation, leading to subsequent cardiac remodeling and failure in both humans and mice. The induction of BBLN is driven by hypoxia in TOF and/or pressure overload, as evidenced in mouse models.
Keywords:Cardiovascular Diseases, Disease Model, Heart Failure, Animals, Mice
Source:Nature Cardiovascular Research
ISSN:2731-0590
Publisher:Springer Nature
Volume:2
Number:11
Page Range:964-965
Date:November 2023
Official Publication:https://doi.org/10.1038/s44161-023-00357-0
PubMed:View item in PubMed

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