Item Type: | Article |
---|---|
Title: | BLN protein induces cardiac hypertrophy and failure |
Creators Name: | Sperling, S.R. |
Abstract: | BBLN, a protein with predominantly uncharted functions, serves as an instigator of CAMK2D autophosphorylation, leading to subsequent cardiac remodeling and failure in both humans and mice. The induction of BBLN is driven by hypoxia in TOF and/or pressure overload, as evidenced in mouse models. |
Keywords: | Cardiovascular Diseases, Disease Model, Heart Failure, Animals, Mice |
Source: | Nature Cardiovascular Research |
ISSN: | 2731-0590 |
Publisher: | Springer Nature |
Volume: | 2 |
Number: | 11 |
Page Range: | 964-965 |
Date: | November 2023 |
Official Publication: | https://doi.org/10.1038/s44161-023-00357-0 |
PubMed: | View item in PubMed |
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