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New light on a long-known protein family

Item Type:Review
Title:New light on a long-known protein family
Creators Name:Andersen, O.M. and Petersen, H.H.
Abstract:A family affair: The view of the LDLR family has shifted from a family of endocytosis receptors towards a class of membrane proteins participating in complex signaling pathways. The receptors play essential roles in several physiological processes but are also involved in many pathological events, such as atherosclerosis and Alzheimers disease; this makes them attractive drug targets.
Keywords:Alzheimers Disease, Low-density Lipoprotein Receptor, Membrane Proteins, Signal Transduction, Steroid Metabolism, Animals
Source:ChemBioChem
ISSN:1439-4227
Publisher:Wiley-VCH
Volume:4
Number:11
Page Range:1137-1146
Date:7 November 2003
Official Publication:https://doi.org/10.1002/cbic.200300580
PubMed:View item in PubMed

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