Item Type: | Article |
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Title: | Die Rolle der Polychemotherapie im multimodalen Behandlungskonzept der malignen Knochentumoren [The role of polychemotherapy in the management of malignant bone tumors] |
Creators Name: | Reichardt, P. and Doerken, B. |
Abstract: | Osteosarcoma,chondrosarcoma and Ewingtumors are the most common primary malignant bone tumors.Due to early hematogenous dissemination, surgery alone is able to cure less than 20% of patients with osteosarcoma. In Ewing-tumors less than 10% of patients will be cured with local treatment alone.By the use of aggressive polychemotherapy, given both pre- and post-surgery, cure rates of more than 50% for Ewing-tumors and about 70% for osteosarcoma could be achieved.Thus,chemotherapy is an indispensable part of the multimodal treatment of these tumor types. Chondrosarcomas are usually more highly differentiated and therefore show a lower rate of metastasis. The use of chemotherapy is not established in these tumors. |
Keywords: | Osteosarcoma, Ewing Tumors, Chondrosarcoma, Multimodality Treatment, Polychemotherapy |
Source: | Chirurg |
ISSN: | 0009-4722 |
Publisher: | Springer |
Volume: | 73 |
Number: | 12 |
Page Range: | 1170-1173 |
Date: | 1 December 2002 |
Official Publication: | https://doi.org/10.1007/s00104-002-0555-9 |
PubMed: | View item in PubMed |
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