Item Type: | Article |
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Title: | cag+ Helicobacter pylori induces homotypic aggregation of macrophage-like cells by up-regulation and recruitment of intracellular adhesion molecule 1 to the cell surface |
Creators Name: | Moese, S., Selbach, M., Meyer, T.F. and Backert, S. |
Abstract: | Infection with cag+ but not cag-negative Helicobacter pylori leads to the formation of large homotypic aggregates of macrophage-like cells. Intracellular adhesion molecule 1 is up-regulated and recruited to the cell surface of infected cells and mediates the aggregation via lymphocyte function-associated molecule 1. This signaling may regulate cell-cell interactions and inflammatory responses. |
Keywords: | Bacterial Antigens, Bacterial Proteins, Cell Aggregation, Cell Membrane, Drosophila Proteins, Helicobacter pylori |
Source: | Infection and Immunity |
ISSN: | 0019-9567 |
Publisher: | American Society for Microbiology |
Volume: | 70 |
Number: | 8 |
Page Range: | 4687-4691 |
Date: | August 2002 |
Official Publication: | https://doi.org/10.1128/IAI.70.8.4687-4691.2002 |
PubMed: | View item in PubMed |
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