Browse by Research Team

Article

Enhanced resolution of sedimentation coefficient distribution profiles by extrapolation to infinite time.
Behlke, J. and Ristau, O.
European Biophysics Journal 39 (3): 449-455. February 2010

Structural and functional characterization of human Iba proteins.
Schulze, J.O., Quedenau, C., Roske, Y., Adam, T., Schueler, H., Behlke, J., Turnbull, A.P., Sievert, V., Scheich, C., Mueller, U., Heinemann, U. and Buessow, K.
FEBS Journal 275 (18): 4627-4640. September 2008

Crystal structures of human saposins C and D: implications for lipid recognition and membrane interactions.
Rossmann, M., Schultz-Heienbrok, R., Behlke, J., Remmel, N., Alings, C., Sandhoff, K., Saenger, W. and Maier, T.
Structure 16 (5): 809-817. 7 May 2008

Self-association of adrenodoxin studied by using analytical ultracentrifugation.
Behlke, J., Ristau, O., Mueller, E.C., Hannemann, F. and Bernhardt, R.
Biophysical Chemistry 125 (1): 159-165. January 2007

Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats.
Haase, H., Dobbernack, G., Tünnemann, G., Karczewski, P., Cardoso, C., Petzhold, D., Schlegel, W.P., Lutter, S., Pierschalek, P., Behlke, J. and Morano, I.
FASEB Journal 20 (7): 865-873. May 2006

Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.
Andersen, O.M., Schmidt, V., Spoelgen, R., Gliemann, J., Behlke, J., Galatis, D., McKinstry, W.J., Parker, M.W., Masters, C.L., Hyman, B.T., Cappai, R. and Willnow, T.E.
Biochemistry 45 (8): 2618-2628. 28 February 2006

A new possibility to recognize the concentration dependence of sedimentation coefficients.
Behlke, J. and Ristau, O.
2006

X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
Manjasetty, B.A., Niesen, F.H., Scheich, C., Roske, Y., Goetz, F., Behlke, J., Sievert, V., Heinemann, U. and Buessow, K.
BMC Structural Biology 5 (14): 21. 14 December 2005

Ahnak is critical for cardiac Ca(v)1.2 calcium channel function and its beta-adrenergic regulation.
Haase, H., Alvarez, J., Petzhold, D., Doller, A., Behlke, J., Erdmann, J., Hetzer, R., Regitz-Zagrosek, V., Vassort, G. and Morano, I.
FASEB Journal 19 (14): 1969-1977. December 2005

Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation.
Behlke, J., Koellner, G. and Bzowska, A.
Zeitschrift fuer Naturforschung C, A Journal of Biosciences 60 (11-12): 927-931. November 2005

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen, O.M., Reiche, J., Schmidt, V., Gotthardt, M., Spoelgen, R., Behlke, J., von Arnim, C.A.F., Breiderhoff, T., Jansen, P., Wu, X., Bales, K.R., Cappai, R., Masters, C.L., Gliemann, J., Mufson, E.J., Hyman, B.T., Paul, S.M., Nykjaer, A. and Willnow, T.E.
Proceedings of the National Academy of Sciences of the United States of America 102 (38): 13461-13466. 7 September 2005

Size determination of cyanobacterial and higher plant photosystem II by gel permeation chromatography, light scattering, and ultracentrifugation.
Zouni, A., Kern, J., Frank, J., Hellweg, T., Behlke, J., Saenger, W. and Irrgang, K.D.
Biochemistry 44 : 4572-4581. 1 January 2005

Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization.
Turnbull, A.P., Kuemmel, D., Prinz, B., Holz, C., Schultchen, J., Lang, C., Niesen, F.H., Hofmann, K.P., Delbrueck, H., Behlke, J., Mueller, E.C., Jarosch, E., Sommer, T. and Heinemann, U.
EMBO Journal 24 (5): 875-884. 1 January 2005

Sedimentation equilibrium: a valuable tool to study homologous and heterogeneous interactions of proteins or proteins and nucleic acids.
Behlke, J. and Ristau, O.
European Biophysics Journal with Biophysics Letters 32 (5): 427-431. 1 August 2003

Human CYP1A1 allelic variants: baculovirus expression and purification, hydrodynamic, spectral, and catalytical properties and their potency in the formation of all-trans-retinoic acid.
Chernogolov, A., Behlke, J., Schunck, W.H., Roots, I. and Schwarz, D.
Protein Expression and Purification 28 (2): 259-269. April 2003

The tailspike protein of Shigella phage Sf6 - A structural homolog of Salmonella phage p22 tailspike protein without sequence similarity in the beta-helix domain.
Freiberg, A., Morona, R., Van den Bosch, L., Jung, C., Behlke, J., Carlin, N., Seckler, R. and Baxa, U.
Journal of Biological Chemistry 278 (3): 1542-1548. 17 January 2003

In vitro and in vivo stability of the epsilon2zeta2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system.
Camacho, A.G., Misselwitz, R., Behlke, J., Ayora, S., Welfle, K., Meinhart, A., Lara, B., Saenger, W., Welfle, H. and Alonso, J.C.
Biological Chemistry 383 (11): 1701-1713. November 2002

Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition.
Izsvak, Z., Khare, D., Behlke, J., Heinemann, U., Plasterk, R.H. and Ivics, Z.
Journal of Biological Chemistry 277 (37): 34581-34588. 13 September 2002

CopR binds and bends its target DNA: a footprinting and fluorescence resonance energy transfer study.
Steinmetzer, K., Behlke, J., Brantl, S. and Lorenz, M.
Nucleic Acids Research 30 (9): 2052-2060. 1 May 2002

A new approximate whole boundary solution of the Lamm differential equation for the analysis of sedimentation velocity experiments.
Behlke, J. and Ristau, O.
Biophysical Chemistry 95 (1): 59-68. 1 January 2002

Plasmid pIP501 encoded transcriptional repressor CopR: single amino acids involved in dimerization are also important for folding of the monomer.
Steinmetzer, K., Kuhn, K., Behlke, J., Golbik, R. and Brantl, S.
Plasmid 47 (3): 201-209. 1 January 2002

Cellular uptake of the Clostridium perfringens binary iota-toxin.
Bloecker, D., Behlke, J., Aktories, K. and Barth, H.
Infection and Immunity 69 : 2980-2987. 1 January 2001

Interaction of fluorescence labeled single-stranded DNA with hexameric DNA-helicase RepA: A photon and fluorescence correlation spectroscopy study.
Xu, H., Frank, J., Trier, U., Hammer, S., Schroeder, W., Behlke, J., Schaefer-Korting, M., Holzwarth, J.F. and Saenger, W.
Biochemistry 40 (24): 7211-7218. 1 January 2001

Protein oligomerization requires correct folding of the protomers.
Behlke, J.
Nova Acta Leopoldina Suppl. 16 : 93-95. 1 January 2001

Regulation of phosphotransferase activity of hexokinase 2 from Saccharomyces cerevisiae by modification at serine-14.
Golbik, R., Naumann, M., Otto, A., Mueller, E.C., Behlke, J., Reuter, R. and Kriegel, T.M.
Biochemistry 40 (4): 1083-1090. 1 January 2001

Self-association studies on the EphB2 receptor SAM domain using analytical ultracentrifugation.
Behlke, J., Labudde, D. and Ristau, O.
European Biophysics Journal with Biophysics Letters 30 (6): 411-415. 1 January 2001

Colloidal properties of human transferrin receptor in detergent free solution.
Schueler, J., Frank, J., Behlke, J., Saenger, W. and Georgalis, Y.
Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology 1480 (1-2): 211-221. 14 July 2000

Transcriptional repressor CopR: Structure model-based localization of the deoxyribonucleic acid binding motif.
Steinmetzer, K., Hillisch, A., Behlke, J. and Brantl, S.
Proteins: Structure, Function, and Bioinformatics 38 (4): 393-406. 1 March 2000

Analysis of protein self-association under conditions of the thermodynamic non-ideality.
Behlke, J. and Ristau, O.
Biophysical Chemistry 87 (1): 1-13. 1 January 2000

Cellular uptake of Clostridium botulinum C2 toxin requires oligomerization and acidification.
Barth, H., Bloecker, D., Behlke, J., Bergsma-Schutter, W., Brisson, A., Benz, R. and Aktories, K.
Journal of Biological Chemistry 275 (25): 18704-18711. 1 January 2000

Imaging DNA loops induced by restriction endonuclease EcoRII. A single amino acid substitution uncouples target recognition from cooperative DNA interaction and cleavage.
Muecke, M., Lurz, R., Mackeldanz, P., Behlke, J., Krueger, D.H. and Reuter, M.
Journal of Biological Chemistry 275 (39): 30631-30637. 1 January 2000

Interaction of different oligomeric states of hexameric DNA-helicase RepA with single-stranded DNA studied by analytical ultracentrifugation.
Xu, H., Frank, J., Holzwarth, J.F., Saenger, W. and Behlke, J.
FEBS Letters 482 (3): 180-184. 1 January 2000

epsilon-Crystallin from duck eye lens. Comparisonof its quaternary structure and stability with other lactate dehydrogenases and complex formation with alpha-crystallin.
Berr, K., Wassenberg, D., Lilie, H., Behlke, J. and Jaenicke, R.
European Journal of Biochemistry 267 (17): 5413-5420. 1 January 2000

A 6 bp Z-DNA hairpin binds two Zalpha domains from the human RNA editing enzyme ADAR1.
Schade, M., Behlke, J., Lowenhaupt, K., Herbert, A., Rich, A. and Oschkinat, H.
FEBS Letters 458 : 27-31. 1 January 1999

Analysis of the thermodynamic non-ideality of proteins by sedimentation equilibrium experiments.
Behlke, J. and Ristau, O.
Biophysical Chemistry 76 : 13-23. 1 January 1999

Effect of the ionic environment on the molecular structure of bacteriophage SPP1 portal protein.
Jekow, P., Behlke, J., Tichelaar, W., Lurz, R., Regalla, M., Hinrichs, W. and Tavares, P.
European Journal of Biochemistry 264 : 724-735. 1 January 1999

Interaction of the capsid protein p24 (HIV-1) with sequence-derived peptides: influence on p24 dimerization.
Hilpert, K., Behlke, J., Scholz, C., Misselwitz, R., Schneider-Mergener, J. and Hoehne, W.
Virology 254 : 6-10. 1 January 1999

Water-soluble beta-sheet models which self-assemble into fibrillar structures.
Janek, K., Behlke, J., Zipper, J., Fabian, H., Georgalis, Y., Beyermann, M., Bienert, M. and Krause, E.
Biochemistry 38 : 8246-8252. 1 January 1999

Analytical ultracentrifugation of the nitrogenase of Azotobacter vinelandii under anaerobic conditions.
Behlke, J. and Ristau, O.
Progress Colloid Polymers Science 113 : 182-184. 1999

Plasmid pIP501 encoded transcriptional repressor CopR binds to its target DNA as a dimer.
Steinmetzer, K., Behlke, J. and Brantl, S.
Journal of Molecular Biology 283 : 595-603. 30 October 1998

An improved approximate solution of the Lamm equation for the simultaneous estimation of sedimentation and diffusion coefficients from sedimentation velocity experiments.
Behlke, J. and Ristau, O.
Biophysical Chemistry 70 : 133-146. 16 February 1998

Gross conformation of dissolved angiotensin derived from sedimentation and diffusion coefficients.
Behlke, J. and Ristau, O.
Biochemical Society Transactions 26 : 758-761. 1 January 1998

Protein crystallization with and without precipitants.
Behlke, J., Marg, A. and Paeschke, M.
Journal of Applied Crystallography 30 (5/1): 559-560. 1 October 1997

Nucleotide-dependent complex formation between the Escherichia coli chaperonins GroEL and GroES studied under equilibrium conditions.
Behlke, J., Ristau, O. and Schoenfeld, H.J.
Biochemistry 36 (17): 5149-5156. 29 April 1997

Hairpin-dimer equilibrium of a parallel-stranded DNA hairpin: formation of a four-stranded complex.
Dornberger, U., Behlke, J., Birch-Hirschfeld, E. and Fritzsche, H.
Nucleic Acids Research 25 (4): 822-829. 15 February 1997

Analysis of interacting biopolymer systems by analytical ultracentrifugation.
Behlke, J. and Ristau, O.
European Biophysics Journal with Biophysics Letters 25 : 325-332. 1 January 1997

Rapid molecular mass determination by sedimentation velocity experiments and direct fitting of the concentration profiles.
Behlke, J. and Ristau, O.
Progress Colloid Polymers Science 107 : 27-35. 1 January 1997

Recent developments of analytical ultracentrifugation in biopolymer research.
Behlke, J.
European Biophysics Journal with Biophysics Letters 25 : 319-323. 1 January 1997

Molecular mass determination by sedimentation velocity experiments and direct fitting of the concentration profiles.
Behlke, J. and Ristau, O.
Biophysical Journal 72 (1): 428-434. January 1997

Pyridoxal phosphate induced association reactions of adrenodoxin and adrenodoxin-reductase.
Behlke, J. and Ristau, O.
Biochemical and Biophysical Research Communications 219 : 663-667. 1 January 1996

Complex formation and crystallization of adrenodoxin-reductase with adrenodoxin.
Behlke, J., Ristau, O. and Marg, A.
Progress Colloid Polymers Science 99 : 63-68. 1 January 1995

Supramolecular structure of the small heat shock protein Hsp25.
Behlke, J., Dube, P., van Heel, M., Wieske, M., Hayess, K., Benndorf, R. and Lutsch, G.
Progress Colloid Polymers Science 99 : 87-93. 1 January 1995

Crystallization and x-ray examination of bovine adrenodoxin.
Marg, A., Kuban, R.J., Behlke, J., Dettmer, R. and Ruckpaul, K.
Journal of Molecular Biology 227 : 945-947. 1 January 1992

Modulation of the beta-adrenergic-response in cultured rat heart cells. II. Mammary derived growth inhibitor (MGDI) blocks induction of beta-adrenergic supersensitivity. Dissocition from lipid-binding activity of MDGI.
Wallukat, G., Boehmer, F.D., Engstroem, U., Langen, P., Hollenberg, M., Behlke, J., Kuehn, H. and Grosse, R.
Molecular and Cellular Biochemistry 102 : 49-60. 1 January 1991

Book Section

LAMMNUM: A program to study self-associating macromolecules in sedimentation velocity experiments.
Behlke, J. and Ristau, O.
In: Analytical Ultracentrifugation: Techniques and Methods. RSC Publishing, Cambridge, U.K., 122-132. ISBN 0-854-04547-3 2006

Analytical ultracentrifugation: a valuable tool to recognize crystallization conditions of proteins.
Behlke, J. and Ristau, O.
In: Processing by Centrifugation. Kluwer, New York, 61-70. ISBN 0306-46654-6 20 January 2001

Thesis

Beitraege zur Struktur und Funktion des kleinen Saeuger-Stressproteins HSP25 unter besonderer Beruecksichtigung der Wechselwirkung mit Actin.
Wieske, M.
UNSPECIFIED thesis, UNSPECIFIED. 22 September 1998

Patent

Verfahren zur Kristallisation von Proteinen.
Behlke, J. and Knespel, A.
DE19549267A1. 3 July 1997

Review

Molecular parameters from sedimentation velocity experiments: whole boundary fitting using approximate and numerical solutions of lamm equation.
Demeler, B., Behlke, J. and Ristau, O.
Methods in Enzymology 321 : 38-66. 1 January 2000

Molecular chaperones and their interactions investigated by analytical unltracentrifugation and other methodologies.
Schoenfeld, H.J. and Behlke, J.
Methods in Enzymology 290 : 269-296. 1 January 1998

Letter

Observation of precrystallization aggregation in protein solutions during centrifugation.
Behlke, J. and Knespel, A.
Journal of Crystal Growth 158 : 388-391. 1 January 1996