Browse by Research Team

Acta Obstetricia et Gynecologica Scandinavica

Blood pressure and hypertension during pregnancy in women with polycystic ovary syndrome. Odense Child Cohort.
Nielsen, J.H., Birukov, A., Jensen, R.C., Kyhl, H.B., Jørgensen, J.S., Andersen, M.S. and Glintborg, D.
Acta Obstetricia et Gynecologica Scandinavica 99 (10): 1354-1363. October 2020

Acta Physiologica

Metformin modulates microbiota and improves blood pressure and cardiac remodeling in a rat model of hypertension.
Wimmer, M.I., Bartolomaeus, H., Anandakumar, H., Chen, C.Y., Vecera, V., Kedziora, S., Kamboj, S., Schumacher, F., Pals, S., Rauch, A., Meisel, J., Potapenko, O., Yarritu, A., Bartolomaeus, T.U.P., Samaan, M., Thiele, A., Stürzbecher, L., Geisberger, S.Y., Kleuser, B., Oefner, P.J., Haase, N., Löber, U., Gronwald, W., Forslund-Startceva, S.K., Muller, D.N. and Wilck, N.
Acta Physiologica : e14226. 10 September 2024 (In Press)

Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury.
Kusch, A., Hoff, U., Bubalo, G., Zhu, Y., Fechner, M., Schmidt-Ullrich, R., Marko, L., Müller, D.N., Schmidt-Ott, K.M., Gürgen, D., Blum, M., Schunck, W.H. and Dragun, D.
Acta Physiologica 208 (1): 25-40. May 2013

Neutrophil gelatinase-associated lipocalin: pathophysiology and clinical applications.
Singer, E., Markó, L., Paragas, N., Barasch, J., Dragun, D., Müller, D.N., Budde, K. and Schmidt-Ott, K.M.
Acta Physiologica 207 (4): 663-672. April 2013

Advances in Nephrology from the Necker Hospital

Angiotensin-induced inflammation and novel approaches to treatment.
Mueller, D.N., Dechend, R., Fiebeler, A., Park, J.K., Haller, H. and Luft, F.C.
Advances in Nephrology from the Necker Hospital 31 : 89-103. 2001

American Journal of Clinical Nutrition

Ultra-Long-term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion.
Birukov, A., Rakova, N., Lerchl, K., Olde Engberink, R.H.G., Johannes, B., Wabel, P., Moissl, U., Rauh, M., Luft, F.C. and Titze, J.
American Journal of Clinical Nutrition 104 (1): 49-57. July 2016

American Journal of Hypertension

Progression of kidney injury and cardiac remodeling in obese spontaneously hypertensive rats: the role of renal sympathetic innervation.
Linz, D., Hohl, M., Schuetze, J., Mahfoud, F., Speer, T., Linz, B., Hübschle, T., Juretschke, H.P., Dechend, R., Geisel, J., Rütten, H. and Böhm, M.
American Journal of Hypertension 28 (2): 256-265. February 2015

Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertension.
Parrish, M.R., Wallace, K., Tam Tam, K.B., Herse, F., Weimer, A., Wenzel, K., Wallukat, G., Ray, L.F., Arany, M., Cockrell, K., Martin, J.N., Dechend, R. and Lamarca, B.
American Journal of Hypertension 24 (7): 835-840. July 2011

The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancy.
Parrish, M.R., Murphy, S.R., Rutland, S., Wallace, K., Wenzel, K., Wallukat, G., Keiser, S., Ray, L.F., Dechend, R., Martin, J.N., Granger, J.P. and Lamarca, B.
American Journal of Hypertension 23 (8): 911-916. August 2010

Modulating angiotensin II-induced inflammation by HMG Co-A reductase inhibition.
Dechend, R., Fiebler, A., Lindschau, C., Bischoff, H., Mueller, D.N., Park, J.K., Dietz, R., Haller, H. and Luft, F.C.
American Journal of Hypertension 14 : 55S-61S. 1 January 2001

American Journal of Kidney Diseases

Growth arrest specific protein 6/Axl signaling in human inflammatory renal diseases.
Fiebeler, A., Park, J.K., Muller, D.N., Lindschau, C., Mengel, M., Merkel, S., Banas, B., Luft, F.C. and Haller, H.
American Journal of Kidney Diseases 43 (2): 286-295. 1 January 2004

American Journal of Obstetrics and Gynecology

Early pregnancy angiogenic markers and spontaneous abortion: an Odense Child Cohort study.
Andersen, L.B., Dechend, R., Karumanchi, S.A., Nielsen, J., Joergensen, J.S., Jensen, T.K. and Christesen, H.T.
American Journal of Obstetrics and Gynecology 215 (5): 594.e1-594.e11. November 2016

Progesterone supplementation attenuates hypertension and the autoantibody to the angiotensin II type I receptor in response to elevated interleukin-6 during pregnancy.
Amaral, L.M., Kipprono, L., Cornelius, D.C., Shoemaker, C., Wallace, K., Moseley, J., Wallukat, G., Martin, J.N., Dechend, R. and Lamarca, B.
American Journal of Obstetrics and Gynecology 211 (2): 158.e1-158.e6. August 2014

Seeking the mechanism(s) of action for corticosteroids in HELLP syndrome: SMASH study.
Wallace, K., Martin, J.N., Tam, K.T., Wallukat, G., Dechend, R., Lamarca, B. and Owens, M.Y.
American Journal of Obstetrics and Gynecology 208 (5): 380.e1-380.e8. May 2013

American Journal of Pathology

Increased apoptosis, altered oxygen signaling, and antioxidant defenses in first-trimester pregnancies with high-resistance uterine artery blood flow.
Leslie, K., Whitley, G.S.J., Herse, F., Dechend, R., Ashton, S.V., Laing, K., Thilaganathan, B. and Cartwright, J.E.
American Journal of Pathology 185 (10): 2731-2741. October 2015

Placental fractalkine is up-regulated in severe early-onset preeclampsia.
Siwetz, M., Dieber-Rotheneder, M., Cervar-Zivkovic, M., Kummer, D., Kremshofer, J., Weiss, G., Herse, F., Huppertz, B. and Gauster, M.
American Journal of Pathology 185 (5): 1334-1343. May 2015

A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury.
Muller, D.N., Theuer, J., Shagdarsuren, E., Kaergel, E., Honeck, H., Park, J.K., Markovic, M., Barbosa-Sicard, E., Dechend, R., Wellner, M., Kirsch, T., Fiebeler, A., Rothe, M., Haller, H., Luft, F.C. and Schunck, W.H.
American Journal of Pathology 164 (2): 521-532. 1 January 2004

Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
Finckenberg, P., Inkinen, K., Ahonen, J., Merasto, S., Louhelainen, M., Vapaatalo, H., Mueller, D., Ganten, D., Luft, F.C. and Mervaala, E.
American Journal of Pathology 163 (1): 355-366. July 2003

Immunosuppressive treatment protects against angiotensin II-induced renal damage.
Muller, D.N., Shagdarsuren, E., Park, J.K., Dechend, R., Mervaala, E., Hampich, F., Fiebeler, A., Ju, X., Finckenberg, P., Theuer, J., Viedt, C., Kreuzer, J., Heidecke, H., Haller, H., Zenke, M. and Luft, F.C.
American Journal of Pathology 161 (5): 1679-1693. November 2002

Angiotensin II (AT1) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.
Mueller, D.N., Mervaala, E.M.A., Dechend, R., Fiebeler, A., Park, J.K., Schmidt, F., Theuer, J., Breu, V., Mackman, N., Luther, T., Schneider, W., Gulba, D., Ganten, D., Haller, H. and Luft, F.C.
American Journal of Pathology 157 : 111-122. 1 July 2000

American Journal of Physiology Endocrinology and Metabolism

Functional changes in the uterine artery precede the hypertensive phenotype in a transgenic model of hypertensive pregnancy.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C., Bader, M., Dechend, R. and Brosnihan, K.B.
American Journal of Physiology Endocrinology and Metabolism 309 (9): E811-E817. 1 November 2015

American Journal of Physiology Heart and Circulatory Physiology

Angiotensin II-induced sudden arrhythmic death and electrical remodeling.
Fischer, R., Dechend, R., Gapelyuk, A., Shagdarsuren, E., Gruner, K., Gruner, A., Gratze, P., Qadri, F., Wellner, M., Fiebeler, A., Dietz, R., Luft, F.C., Mueller, D.N. and Schirdewan, A.
American Journal of Physiology Heart and Circulatory Physiology 293 (2): H1242-H1253. 1 August 2007

American Journal of Physiology Regulatory Integrative and Comparative Physiology

Blockade of endogenous angiotensin II type I receptor agonistic autoantibody activity improves mitochondria reactive oxygen species and hypertension in a rat model of preeclampsia.
Vaka, V.R., Cunningham, M., Deer, E., Franks, M., Ibrahim, T., Amaral, L., Usry, N., Cornelius, D.C., Dechend, R., Wallukat, G. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 318 (2): R256-R262. 27 January 2020

Interleukin-4 supplementation improves the pathophysiology of hypertension in response to placental ischemia in RUPP rats.
Cottrell, J.N., Amaral, L.M., Harmon, A.C., Cornelius, D.C., Cunningham, M.W., Vaka, V.R., Ibrahim, T., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 316 (2): R165-R171. February 2019

Vitamin D supplementation reduces some AT1-AA induced downstream targets implicated in preeclampsia including hypertension.
Faulkner, J.L., Amaral, L.M., Cornelius, D.C., Cunningham, M.W., Ibrahim, T., Heep, A., Campbell, N., Usry, N., Wallace, K., Herse, F., Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 312 (1): R125-R131. 1 January 2017

Reduced uterine perfusion pressure T-helper 17 cells cause pathophysiology associated with preeclampsia during pregnancy.
Cornelius, D.C., Amaral, L.M., Wallace, K., Campbell, N., Thomas, A.J., Scott, J., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 311 (6): R1192-R1199. 1 December 2016

Vitamin D supplementation improves pathophysiology in a rat model of preeclampsia.
Faulkner, J.L., Cornelius, D.C., Amaral, L.M., Harmon, A.C., Cunningham, M.W., Darby, M.M., Ibrahim, T., Thomas, D.S., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 310 (4): R346-R354. 15 February 2016

Blockade of CD40 ligand for intercellular communication reduces hypertension, placental oxidative stress, and AT1-AA in response to adoptive transfer of CD4(+) T lymphocytes from RUPP rats.
Cornelius, D.C., Castillo, J., Porter, J., Amaral, L.M., Campbell, N., Paige, A., Thomas, A.J., Harmon, A., Cunningham, M.W., Wallace, K., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309 (10): R1243-R1250. 15 November 2015

An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia.
Cornelius, D.C., Amaral, L.M., Harmon, A., Wallace, K., Thomas, A.J., Campbell, N., Scott, J., Herse, F., Haase, N., Moseley, J., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 309 (8): R884-R891. 15 October 2015

IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy.
Dhillion, P., Wallace, K., Herse, F., Scott, J., Wallukat, G., Heath, J., Mosely, J., Martin, J.N., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 303 (4): R353-R358. 15 August 2012

Activating autoantibodies to the angiotensin receptor are important in mediating hypertension in response to adoptive transfer of RUPP CD4+ T lymphocytes.
Novotny, S.R., Wallace, K., Heath, J., Moseley, J., Dhillon, P., Weimer, A., Wallukat, G., Herse, F., Wenzel, K., Martin, J.N., Dechend, R. and Lamarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 302 (10): R1197-R1201. 15 May 2012

American Journal of Physiology Renal Physiology

B2 cells contribute to hypertension and natural killer cell activation possibly via AT1-AA in response to placental ischemia.
Herrock, O.T., Deer, E., Amaral, L.M., Campbell, N., Lemon, J., Ingram, N., Cornelius, D.C., Turner, T., Fitzgerald, S., Ibrahim, T., Dechend, R., Wallukat, G. and LaMarca, B.
American Journal of Physiology Renal Physiology 324 (2): F179-F192. February 2023

Normal-range urinary albumin excretion associates with blood pressure and renal electrolyte handling in pregnancy.
Birukov, A., Andersen, M.S., Jørgensen, J.S., Kitlen, G., Rakova, N., Nielsen, J.H., Andersen, L.B., Dechend, R. and Jensen, B.L.
American Journal of Physiology Renal Physiology 319 (1): F1-F7. July 2020

The direct renin inhibitor aliskiren localizes and persists in rat kidneys.
Feldman, D.L., Jin, L., Xuan, H., Persohn, E., Zhou, W., Schuetz, H., Park, J.K., Mueller, D.N. and Luft, F.C.
American Journal of Physiology Renal Physiology 305 (11): F1593-F1602. December 2013

American Journal of Reproductive Immunology

Soluble B7-H4 blood serum levels are elevated in women at high risk for preeclampsia in the first trimester, as well as in patients with confirmed preeclampsia.
Mach, P., Nolte-Boenigk, L., Droste, L., Fox, L., Frank, M., Schmidt, B., Herse, F., Verlohren, S., Wicherek, L., Iannaccone, A., Birdir, C., Andrikos, D., Kimmig, R., Gellhaus, A. and Köninger, A.
American Journal of Reproductive Immunology 80 (3): e12988. September 2018

Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy.
Ibrahim, T., Przybyl, L., Harmon, A.C., Amaral, L.M., Faulkner, J.L., Cornelius, D., Cunningham, M.W., Hünig, T., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Reproductive Immunology 78 (5): e12724. November 2017

Angiotensin II type 1 receptor autoantibody (AT1-AA)-mediated pregnancy hypertension.
Herse, F. and Lamarca, B.
American Journal of Reproductive Immunology 69 (4): 413-418. April 2013

American Journal of Transplantation

Pretransplant sensitization against angiotensin II type 1 receptor is a risk factor for acute rejection and graft loss.
Giral, M., Foucher, Y., Dufay, A., Van Huyen, J.P.D., Renaudin, K., Moreau, A., Philippe, A., Hegner, B., Dechend, R., Heidecke, H., Brouard, S., Cesbron, A., Castagnet, S., Devys, A., Soulillou, J.P. and Dragun, D.
American Journal of Transplantation 13 (10): 2567-2576. October 2013

Analytical Cellular Pathology

Predictive and prognostic value of sPRR in patients with primary epithelial ovarian cancer.
Kreienbring, K., Franz, A., Richter, R., Dragun, D., Heidecke, H., Dechend, R., Mueller, D.N., Sehouli, J. and Braicu, E.I.
Analytical Cellular Pathology 2016 : 6845213. 2016

Angewandte Chemie International Edition

Direct zinc finger protein persulfidation by H(2)S is facilitated by Zn(2+).
Lange, M., Ok, K., Shimberg, G.D., Bursac, B., Markó, L., Ivanović-Burmazović, I., Michel, S. and Filipovic, M.R.
Angewandte Chemie International Edition 58 (24): 7997-8001. 11 June 2019

Angiology

StaBle angina: peRceptIon of neeDs, quality of life and manaGemEnt of patients (BRIDGE study) - a multinational European physician survey.
Ambrosio, G., Collins, P., Dechend, R., Lopez-Sendon, J., Manolis, A.J. and Camm, A.J.
Angiology 70 (5): 397-406. 1 May 2019

Annals of Medicine

Immune mechanisms in angiotensin II-induced target-organ damage.
Luft, F.C., Dechend, R. and Mueller, D.N.
Annals of Medicine 44 (Suppl 1): S49-S54. June 2012

Prorenin receptor regulates more than the renin-angiotensin system.
Mueller, D.N., Binger, K.J. and Riediger, F.
Annals of Medicine 44 (Suppl 1): S43-S48. June 2012

Annals of the Rheumatic Diseases

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis.
Riemekasten, G., Philippe, A., Naether, M., Slowinski, T., Mueller, D.N., Heidecke, H., Matucci-Cerinic, M., Czirjak, L., Lukitsch, I., Becker, M., Kill, A., van Laar, J.M., Catar, R., Luft, F.C., Burmester, G.R., Hegner, B. and Dragun, D.
Annals of the Rheumatic Diseases 70 (3): 530-536. March 2011

Anticancer Research

The role of PAR1 autoantibodies in patients with primary epithelial ovarian cancer.
Kreienbring, K., Franz, A., Richter, R., Dragun, D., Heidecke, H., Müller, D., Mentze, M., Dechend, R., Sehouli, J. and Braicu, E.I.
Anticancer Research 38 (6): 3619-3625. June 2018

Antioxidants & Redox Signaling

Targeting the ubiquitin-proteasome system in atherosclerosis: status quo, challenges, and perspectives.
Wilck, N. and Ludwig, A.
Antioxidants & Redox Signaling 21 (17): 2344-2363. 24 November 2014

Apoptosis

Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types.
Balogh, A., Németh, M., Koloszár, I., Markó, L., Przybyl, L., Jinno, K., Szigeti, C., Heffer, M., Gebhardt, M., Szeberényi, J., Müller, D.N., Sétáló, G. and Pap, M.
Apoptosis 19 (7): 1080-1098. 1 July 2014

Archives of Gynecology and Obstetrics

Lifting the veil of secrecy: maternal and neonatal outcome of oocyte donation pregnancies in Germany.
Altmann, J., Kummer, J., Herse, F., Hellmeyer, L., Schlembach, D., Henrich, W. and Weichert, A.
Archives of Gynecology and Obstetrics 306 (1): 59-69. July 2022

Arteriosclerosis Thrombosis and Vascular Biology

High-salt diet causes expansion of the lymphatic network and increased lymph flow in skin and muscle of rats.
Karlsen, T.V., Nikpey, E., Han, J., Reikvam, T., Rakova, N., Castorena-Gonzalez, J.A., Davis, M.J., Titze, J.M., Tenstad, O. and Wiig, H.
Arteriosclerosis Thrombosis and Vascular Biology 38 (9): 2054-2064. September 2018

Activation of peroxisome proliferator-activated receptor-δ as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis.
Hytönen, J., Leppänen, O., Braesen, J.H., Schunck, W.H., Mueller, D., Jung, F., Mrowietz, C., Jastroch, M., von Bergwelt-Baildon, M., Kappert, K., Heuser, A., Drenckhahn, J.D., Pieske, B., Thierfelder, L., Ylä-Herttuala, S. and Blaschke, F.
Arteriosclerosis Thrombosis and Vascular Biology 36 (8): 1534-1548. August 2016

Heparin strongly induces soluble fms-like tyrosine kinase 1 release in vivo and in vitro.
Searle, J., Mockel, M., Gwosc, S., Datwyler, S.A., Qadri, F., Albert, G.I., Holert, F., Isbruch, A., Klug, L., Mueller, D.N., Dechend, R., Muller, R., Vollert, J.O., Slagman, A., Mueller, C. and Herse, F.
Arteriosclerosis Thrombosis and Vascular Biology 31 (12): 2972-2974. December 2011

Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells.
Batenburg, W.W., de Bruin, R.J., van Gool, J.M., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.
Arteriosclerosis Thrombosis and Vascular Biology 28 (6): 1151-1157. June 2008

Autoimmunity Reviews

Autoantibodies targeting G protein-coupled receptors: an evolving history in autoimmunity. Report of the 4th international symposium.
Cabral-Marques, O., Moll, G., Catar, R., Preuß, B., Bankamp, L., Pecher, A.C., Henes, J., Klein, R., Kamalanathan, A.S., Akbarzadeh, R., van Oostveen, W., Hohberger, B., Endres, M., Koolmoes, B., Levarht, N., Postma, R., van Duinen, V., van Zonneveld, A.J., de Vries-Bouwstra, J., Fehres, C., Tran, F., do Vale, F.Y.N., da Silva Souza, K.B., Filgueiras, I.S., Schimke, L.F., Baiocchi, G.C., de Miranda, G.C., da Fonseca, D.L.M., Freire, P.P., Hackel, A.M., Grasshoff, H., Stähle, A., Müller, A., Dechend, R., Yu, X., Petersen, F., Sotzny, F., Sakmar, T.P., Ochs, H.D, Schulze-Forster, Kai, Heidecke, H., Scheibenbogen, C., Shoenfeld, Y. and Riemekasten, G.
Autoimmunity Reviews 22 (5): 103310. May 2023

Activating auto-antibodies against the AT1 receptor in preeclampsia.
Dechend, R., Mueller, D.N., Wallukat, G., Homuth, V., Krause, M., Dudenhausen, J. and Luft, F.C.
Autoimmunity Reviews 4 (1): 61-65. 1 January 2005

Autophagy

HIF1A and NFAT5 coordinate Na(+)-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Neubert, P., Weichselbaum, A., Reitinger, C., Schatz, V., Schröder, A., Ferdinand, J.R., Simon, M., Bär, A.L., Brochhausen, C., Gerlach, R.G., Tomiuk, S., Hammer, K., Wagner, S., van Zandbergen, G., Binger, K.J., Müller, D.N., Kitada, K., Clatworthy, M.R., Kurts, C., Titze, J., Abdullah, Z. and Jantsch, J.
Autophagy 15 (11): 1899-1916. November 2019

BMC Cardiovascular Disorders

Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats.
Theuer, J., Dechend, R., Muller, D.N., Park, J.K., Fiebeler, A., Barta, P., Ganten, D., Haller, H., Dietz, R. and Luft, F.C.
BMC Cardiovascular Disorders 2 : 3. 18 January 2002

BMC Medical Genetics

Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study.
Kvehaugen, A.S., Melien, Ø., Holmen, O.L., Laivuori, H., Dechend, R. and Staff, A.C.
BMC Medical Genetics 15 : 28. 5 March 2014

BMC Neurology

Electrocardiographic assessments and cardiac events after fingolimod first dose - a comprehensive monitoring study.
Limmroth, V., Ziemssen, T., Lang, M., Richter, S., Wagner, B., Haas, J., Schmidt, S., Gerbershagen, K., Lassek, C., Klotz, L., Hoffmann, O., Albert, C., Schuh, K., Baier-Ebert, M., Wendt, G., Schieb, H., Hoyer, S., Dechend, R. and Haverkamp, W.
BMC Neurology 17 (1): 11. 18 January 2017

BMC Pregnancy and Childbirth

Maternal COVID-19 causing intrauterine foetal demise with microthrombotic placental insufficiency: a case report.
Nonn, O., Bonstingl, L., Sallinger, K., Neuper, L., Fuchs, J., Gauster, M., Huppertz, B., Brislinger, D., El-Heliebi, A., Fluhr, H., Kampelmühler, E. and Klaritsch, P.
BMC Pregnancy and Childbirth 23 (1): 653. 9 September 2023

BMJ Open

Protocol of the Berlin Long-term Observation of Vascular Events (BeLOVE): a prospective cohort study with deep phenotyping and long-term follow up of cardiovascular high-risk patients.
Weber, J.E., Ahmadi, M., Boldt, L.H., Eckardt, K.U., Edelmann, F., Gerhardt, H., Grittner, U., Haubold, K., Hübner, N., Kollmus-Heege, J., Landmesser, U., Leistner, D.M., Mai, K., Müller, D.N., Nolte, C.H., Pieske, B., Piper, S.K., Rattan, S., Rauch, G., Schmidt, S., Schmidt-Ott, K.M., Schönrath, K., Schulz-Menger, J., Schweizerhof, O., Siegerink, B., Spranger, J., Ramachandran, V.S., Witzenrath, M., Endres, M. and Pischon, T.
BMJ Open 13 (10): e076415. 31 October 2023

Maternal haemodynamics in Hypertensive Disorders of Pregnancy under antihypertensive therapy (HyperDiP): study protocol for a prospective observational case-control study.
Palmrich, P., Haase, N., Sugulle, M., Kalafat, E., Khalil, A. and Binder, J.
BMJ Open 13 (6): e065444. June 2023

Basic Research in Cardiology

The renin-angiotensin system in the vessel wall.
Mueller, D.N. and Luft, F.C.
Basic Research in Cardiology 93 (Suppl 2): 7-14. 1 January 1998

Biochemical Journal

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.
Mueller, D.N., Schmidt, C., Barbosa-Sicard, E., Wellner, M., Gross, V., Hercule, H., Markovic, M., Honeck, H., Luft, F.C. and Schunck, W.H.
Biochemical Journal 403 (1): 109-118. April 2007

Biochemical and Biophysical Research Communications

Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily.
Barbosa-Sicard, E., Markovic, M., Honeck, H., Christ, B., Muller, D.N. and Schunck, W.H.
Biochemical and Biophysical Research Communications 329 (4): 1275-1281. 22 April 2005

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Serotonin-induced stereospecific formation and bioactivity of the eicosanoid 17,18-epoxyeicosatetraenoic acid in the regulation of pharyngeal pumping of C. elegans.
Zhou, Y., Rothe, M., Schunck, W.H., Ruess, L. and Menzel, R.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1868 (5): 159304. May 2023

Biology of Sex Differences

The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats.
Warrington, J.P., Fan, F., Duncan, J., Cunningham, M.W., LaMarca, B.B., Dechend, R., Wallukat, G., Roman, R.J., Drummond, H.A., Granger, J.P. and Ryan, M.J.
Biology of Sex Differences 10 (1): 58. 11 December 2019

Biomedicines

Cortisol dose-dependently impairs migration and tube-like formation in a trophoblast cell line and modulates inflammatory and angiogenic genes.
Húngaro, T.G.R, Gregnani, M.F., Alves-Silva, T., Herse, F., Alenina, N., Bader, M. and Araújo, R.C.
Biomedicines 9 (8): 980. August 2021

Biomolecules

The effects of hypoxia on the immune-metabolic interplay in liver cancer.
He, Y., Xu, H., Liu, Y., Kempa, S., Vechiatto, C., Schmidt, R., Yilmaz, E.Y., Heidemann, L., Schnorr, J., Metzkow, S., Schellenberger, E., Häckel, A., Patzak, A., Müller, D.N. and Savic, L.J.
Biomolecules 14 (8): 1024. 17 August 2024

Three-dimensional histological characterization of the placental vasculature using light sheet microscopy.
Freise, L., Behncke, R.Y., Allerkamp, H.H., Sandermann, T.H., Chu, N.H., Funk, E.M., Hondrich, L.J., Riedel, A., Witzel, C., Hansmeier, N.R., Danyel, M., Gellhaus, A., Dechend, R. and Hägerling, R.
Biomolecules 13 (6): 1009. 17 June 2023

Blood

New role for the (pro)renin receptor in T cell development.
Geisberger, S., Maschke, U., Gebhardt, M., Kleinewietfeld, M., Manzel, A., Linker, R.A., Chidgey, A., Dechend, R., Nguyen, G., Daumke, O., Muller, D.N., Wright, M.D. and Binger, K.J.
Blood 126 (4): 504-507. 23 July 2015

Blood Pressure

Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes.
Biala, A., Tauriainen, E., Siltanen, A., Shi, J., Merasto, S., Louhelainen, M., Martonen, E., Finckenberg, P., Mueller, D.N. and Mervaala, E.
Blood Pressure 19 (3): 196-205. June 2010

Blood Pressure Monitoring

The German Hypertension League (Deutsche Hochdruckliga) Quality Seal Protocol for blood pressure-measuring devices: 15-year experience and results from 105 devices for home blood pressure control.
Tholl, U., Lüders, S., Bramlage, P., Dechend, R., Eckert, S., Mengden, T., Nürnberger, J., Sanner, B. and Anlauf, M.
Blood Pressure Monitoring 21 (4): 197-205. August 2016

Canadian Journal of Cardiology

Taking another "look" at sodium.
Titze, J., Müller, D.N. and Luft, F.C.
Canadian Journal of Cardiology 30 (5): 473-475. May 2014

Cardiovascular Research

VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats.
Samuelsson, A.M., Bartolomaeus, T.U.P., Anandakumar, H., Thowsen, I., Nikpey, E., Han, J., Marko, L., Finne, K., Tenstad, O., Eckstein, J., Berndt, N., Kühne, T., Kedziora, S., Sultan, I., Skogstrand, T., Karlsen, T.V., Nurmi, H., Forslund, S.K., Bollano, E., Alitalo, K., Muller, D.N. and Wiig, H.
Cardiovascular Research 119 (7): 1553-1567. 4 July 2023

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage.
Avery, E.G., Bartolomaeus, H., Rauch, A., Chen, C.Y., N'Diaye, G., Löber, U., Bartolomaeus, T.U.P., Fritsche-Guenther, R., Rodrigues, A.F., Yarritu, A., Zhong, C., Fei, L., Tsvetkov, D., Todiras, M., Park, J.K., Markó, L., Maifeld, A., Patzak, A., Bader, M., Kempa, S., Kirwan, J.A., Forslund, S.K., Müller, D.N. and Wilck, N.
Cardiovascular Research 119 (6): 1441-1452. May 2023

Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications.
Gawałko, M., Agbaedeng, T.A., Saljic, A., Mueller, D.N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, T., Schotten, U., Crijns, H.J.G.M., Kalman, J.M., Sanders, P., Nattel, S., Dobrev, D. and Linz, D.
Cardiovascular Research 118 (11): 2415–2427. July 2022

Targeted diets for the gut microbiota and the potential cardiovascular effects.
Chiva-Blanch, G. and Mueller, D.N.
Cardiovascular Research 117 (11): e135–e137. 1 October 2021

Quantifying technical confounders in microbiome studies.
Bartolomaeus, T.U.P., Birkner, T., Bartolomaeus, H., Löber, U., Avery, E.G., Mähler, A., Weber, D., Kochlik, B., Balogh, A., Wilck, N., Boschmann, M., Müller, D.N., Markó, L. and Forslund, S.K.
Cardiovascular Research 117 (3): 863-875. 1 March 2021

Blood pressure changes correlate with short-chain fatty acid production potential shifts under a synbiotic intervention.
Bartolomaeus, H., Avery, E.G., Bartolomaeus, T.U.P., Kozhakhmetov, S., Zhumadilov, Z., Müller, D.N., Wilck, N., Kushugulova, A. and Forslund, S.K.
Cardiovascular Research 116 (7): 1252-1253. June 2020

B-cell lymphoma/leukemia 10 and angiotensin II-induced kidney injury.
Markó, L., Park, J.K., Henke, N., Rong, S., Balogh, A., Klamer, S., Bartolomaeus, H., Wilck, N., Ruland, J., Forslund, S.K., Luft, F.C., Dechend, R. and Müller, D.N.
Cardiovascular Research 116 (5): 1059-1070. 1 April 2020

Scientists on the Spot: Salt, the microbiome, and cardiovascular diseases.
Czesnikiewicz-Guzik, M. and Mueller, D.N.
Cardiovascular Research 114 (10): e72-e73. 1 August 2018

Cardiovascular Ultrasound

Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction.
Grune, J., Ritter, D., Kräker, K., Pappritz, K., Beyhoff, N., Schütte, T., Ott, C., John, C., van Linthout, S., Tschöpe, C., Dechend, R., Muller, D.N., Haase, N., Grune, T., Kintscher, U. and Kuebler, W.M.
Cardiovascular Ultrasound 17 (1): 7. 22 April 2019

Cell

Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism.
Duscha, A., Gisevius, B., Hirschberg, S., Yissachar, N., Stangl, G.I., Eilers, E., Bader, V., Haase, S., Kaisler, J., David, C., Schneider, R., Troisi, R., Zent, D., Hegelmaier, T., Dokalis, N., Gerstein, S., Del Mare-Roumani, S., Amidror, S., Staszewski, O., Poschmann, G., Stühler, K., Hirche, F., Balogh, A., Kempa, S., Träger, P., Zaiss, M.M., Holm, J.B., Massa, M.G., Nielsen, H.B., Faissner, A., Lukas, C., Gatermann, S.G., Scholz, M., Przuntek, H., Prinz, M., Forslund, S.K., Winklhofer, K.F., Müller, D.N., Linker, R.A., Gold, R. and Haghikia, A.
Cell 180 (6): 1067-1080. 19 March 2020

Cell Metabolism

Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs.
Côrte-Real, B.F., Hamad, I., Arroyo Hornero, R., Geisberger, S., Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M.W., Kurniawan, H., Wagner, A., Yosef, N., Weiss, S.N.Y., Schmetterer, K.G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H., Hellings, N., Saeys, Y., Dubois, L.J., Brenner, D., Kempa, S., Hafler, D.A., Stegbauer, J., Linker, R.A., Jantsch, J., Müller, D.N. and Kleinewietfeld, M.
Cell Metabolism 35 (2): 299-315. 7 February 2023

Cutaneous Na(+) storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense.
Jantsch, J., Schatz, V., Friedrich, D., Schröder, A., Kopp, C., Siegert, I., Maronna, A., Wendelborn, D., Linz, P., Binger, K.J., Gebhardt, M., Heinig, M., Neubert, P., Fischer, F., Teufel, S., David, J.P., Neufert, C., Cavallaro, A., Rakova, N., Küper, C., Beck, F.X., Neuhofer, W., Muller, D.N., Schuler, G., Uder, M., Bogdan, C., Luft, F.C. and Titze, J.
Cell Metabolism 21 (3): 493-501. 3 March 2015

Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance.
Rakova, N., Jüttner, K., Dahlmann, A., Schröder, A., Linz, P., Kopp, C., Rauh, M., Goller, U., Beck, L., Agureev, A., Vassilieva, G., Lenkova, L., Johannes, B., Wabel, P., Moissl, U., Vienken, J., Gerzer, R., Eckardt, K.U., Müller, D.N., Kirsch, K., Morukov, B., Luft, F.C. and Titze, J.
Cell Metabolism 17 (1): 125-131. 8 January 2013

Cell and Bioscience

Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts.
Brugger, B.A., Neuper, L., Guettler, J., Forstner, D., Wernitznig, S., Kummer, D., Lyssy, F., Feichtinger, J., Krappinger, J., El-Heliebi, A., Bonstingl, L., Moser, G., Rodriguez-Blanco, G., Bachkönig, O.A., Gottschalk, B., Gruber, M., Nonn, O., Herse, F., Verlohren, S., Frank, H.G., Barapatre, N., Kampfer, C., Fluhr, H., Desoye, G. and Gauster, M.
Cell and Bioscience 13 (1): 163. 8 September 2023

Cellular and Molecular Life Sciences

Downregulation of p53 drives autophagy during human trophoblast differentiation.
Gauster, M., Maninger, S., Siwetz, M., Deutsch, A., El-Heliebi, A., Kolb-Lenz, D., Hiden, U., Desoye, G., Herse, F. and Prokesch, A.
Cellular and Molecular Life Sciences 75 (10): 1839-1855. May 2018

Environmental factors in autoimmune diseases and their role in multiple sclerosis.
Jörg, S., Grohme, D.A., Erzler, M., Binsfeld, M., Haghikia, A., Müller, D.N., Linker, R.A. and Kleinewietfeld, M.
Cellular and Molecular Life Sciences 73 (24): 4611-4622. December 2016

A potential pathophysiological role for galectins and the renin-angiotensin system in preeclampsia.
Blois, S.M., Dechend, R., Barrientos, G. and Staff, A.C.
Cellular and Molecular Life Sciences 72 (1): 39-50. January 2015

Chesley's Hypertensive Disorders in Pregnancy

Agonistic autoantibody-mediated disease.
Dechend, R., Luft, F.C and Lindheimer, M.D.
In: Chesley's Hypertensive Disorders in Pregnancy. UNSPECIFIED, 287-296. ISBN 978-0-12-374213-1 2009

Circulation

High-sensitivity cardiac troponin I enhances preeclampsia prediction beyond maternal factors and the sFlt-1/PlGF ratio.
Bacmeister, L., Goßling, A., Buellesbach, A., Birukov, A., Myers, J.E., Thomas, S.T., Lee, S., Andersen, M.S., Jorgensen, J.S., Diemert, A., Blois, S.M., Arck, P.C., Hecher, K., Herse, F., Blankenberg, S., Dechend, R., Westermann, D. and Zeller, T.
Circulation 149 (2): 95-106. 9 January 2024

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage.
Ercu, M., Mücke, M.B., Pallien, T., Markó, L., Sholokh, A., Schächterle, C., Aydin, A., Kidd, A., Walter, S., Esmati, Y., McMurray, B.J., Lato, D.F., Sunaga-Franze, D.Y., Dierks, P.H., Flores, B.I.M., Walker-Gray, R., Gong, M., Merticariu, C., Zühlke, K., Russwurm, M., Liu, T., Batolomaeus, T.U.P., Pautz, S., Schelenz, S., Taube, M., Napieczynska, H., Heuser, A., Eichhorst, J., Lehmann, M., Miller, D.C., Diecke, S., Qadri, F., Popova, E., Langanki, R., Movsesian, M.A., Herberg, F.W., Forslund, S.K., Müller, D.N., Borodina, T., Maass, P.G., Bähring, S., Hübner, N., Bader, M. and Klussmann, E.
Circulation 146 (23): 1758-1778. 6 December 2022

Salt transiently inhibits mitochondrial energetics in mononuclear phagocytes.
Geisberger, S., Bartolomaeus, H., Neubert, P., Willebrand, R., Zasada, C., Bartolomaeus, T., McParland, V., Swinnen, D., Geuzens, A., Maifeld, A., Krampert, L., Vogl, M., Mähler, A., Wilck, N., Marko, L., Tilic, E., Forslund, S.K., Binger, K.J., Stegbauer, J., Dechend, R., Kleinewietfeld, M., Jantsch, J., Kempa, S. and Müller, D.N.
Circulation 144 (2): 144-158. 13 July 2021

Phosphodiesterase 3A and arterial hypertension.
Ercu, M., Markó, L., Schächterle, C., Tsvetkov, D., Cui, Y., Maghsodi, S., Bartolomaeus, T.U.P., Maass, P.G., Zühlke, K., Gregersen, N., Hübner, N., Hodge, R., Mühl, A., Pohl, B., Molé-Illas, R., Geelhaar, A., Walter, S., Napieczynska, H., Schelenz, S., Taube, M., Heuser, A., Anistan, Y.M., Qadri, F., Todiras, M., Plehm, R., Popova, E., Langanki, R., Eichhorst, J., Lehmann, M., Wiesner, B., Russwurm, M., Forslund, S.K., Kamer, I., Müller, D.N., Gollasch, M., Aydin, A., Bähring, S., Bader, M., Luft, F.C. and Klussmann, E.
Circulation 142 (2): 133-149. 14 July 2020

Natural compound library screening identifies new molecules for the treatment of cardiac fibrosis and diastolic dysfunction.
Schimmel, K., Jung, M., Foinquinos, A., San José, G., Beaumont, J., Bock, K., Grote-Levi, L., Xiao, K., Bär, C., Pfanne, A., Just, A., Zimmer, K., Ngoy, S., López, B., Ravassa, S., Samolovac, S., Janssen-Peters, H., Remke, J., Scherf, K., Dangwal, S., Piccoli, M.T., Kleemiss, F., Kreutzer, F.P., Kenneweg, F., Leonardy, J., Hobuß, L., Santer, L., Do, Q.T., Geffers, R., Braesen, J.H., Schmitz, J., Brandenberger, C., Müller, D.N., Wilck, N., Kaever, V., Bähre, H., Batkai, S., Fiedler, J., Alexander, K.M., Wertheim, B.M., Fisch, S., Liao, R., Diez, J., González, A. and Thum, T.
Circulation 141 (9): 751-767. 3 March 2020

Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H., Balogh, A., Yakoub, M., Homann, S., Markó, L., Höges, S., Tsvetkov, D., Krannich, A., Wundersitz, S., Avery, E.G., Haase, N., Kräker, K., Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J., Kempa, S., Gollasch, M., Zhumadilov, Z., Kozhakhmetov, S., Kushugulova, A., Eckardt, K.U., Dechend, R., Rump, L.C., Forslund, S.K., Müller, D.N., Stegbauer, J. and Wilck, N.
Circulation 139 (11): 1407-1421. 12 March 2019

Disturbed placental imprinting in preeclampsia leads to altered expression of DLX5, a human-specific early trophoblast marker.
Zadora, J., Singh, M., Herse, F., Przybyl, L., Haase, N., Golic, M., Yung, H.W., Huppertz, B., Cartwright, J.E., Whitley, G.S., Johnsen, G.M., Levi, G., Isbruch, A., Schulz, H., Luft, F.C., Müller, D.N., Staff, A.C., Hurst, L.D., Dechend, R. and Izsvák, Z.
Circulation 136 (19): 1824-1839. 7 November 2017

Clarifying the molecular biology of preeclampsia.
Dechend, R.
Circulation 127 (14): F79-F81. April 2013

Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.
Herse, F., LaMarca, B., Hubel, C.A., Kaartokallio, T., Lokki, A.I., Ekholm, E., Laivuori, H., Gauster, M., Huppertz, B., Sugulle, M., Ryan, M.J., Novotny, S., Brewer, J., Park, J.K., Kacik, M., Hoyer, J., Verlohren, S., Wallukat, G., Rothe, M., Luft, F.C., Muller, D.N., Schunck, W.H., Staff, A.C. and Dechend, R.
Circulation 126 (25): 2990-2999. 18 December 2012

Spotlight: Dominik N. Mueller, PhD.
Taylor, J. and Müller, D.N.
Circulation 121 (24): F139-F141. 22 June 2010

Regulatory T cells ameliorate angiotensin II-induced cardiac damage.
Kvakan, H., Kleinewietfeld, M., Qadri, F., Park, J.K., Fischer, R., Schwarz, I., Rahn, H.P., Plehm, R., Wellner, M., Elitok, S., Gratze, P., Dechend, R., Luft, F.C. and Mueller, D.N.
Circulation 119 (22): 2904-2912. 9 June 2009

Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Gratze, P., Dechend, R., Stocker, C., Park, J.K., Feldt, S., Shagdarsuren, E., Wellner, M., Gueler, F., Rong, S., Gross, V., Obst, M., Plehm, R., Alenina, N., Zenclussen, A., Titze, J., Small, K., Yokota, Y., Zenke, M., Luft, F.C. and Mueller, D.N.
Circulation 117 (20): 2645-2656. 20 May 2008

Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.
Fiebeler, A., Nussberger, J., Shagdarsuren, E., Rong, S., Hilfenhaus, G., Al-Saadi, N., Dechend, R., Wellner, M., Meiners, S., Maser-Gluth, C., Jeng, A.Y., Webb, R.L., Luft, F.C. and Mueller, D.N.
Circulation 111 (23): 3087-3094. 1 January 2005

Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells.
Mazak, I., Fiebeler, A., Muller, D.N., Park, J.K., Shagdarsuren, E., Lindschau, C., Dechend, R., Viedt, C., Pilz, B., Haller, H. and Luft, F.C.
Circulation 109 (22): 2792-2800. 8 June 2004

AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase.
Dechend, R., Viedt, C., Mueller, D.N., Ugele, B., Brandes, R.P., Wallukat, G., Park, J.K., Janke, J., Barta, P., Theuer, J., Fiebeler, A., Homuth, V., Dietz, R., Haller, H., Kreuzer, J. and Luft, F.C.
Circulation 107 (12): 1632-1639. 1 April 2003

Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
Dechend, R., Fiebeler, A., Park, J.K., Muller, D.N., Theuer, J., Mervaala, E., Bieringer, M., Gulba, D., Dietz, R., Luft, F.C. and Haller, H.
Circulation 104 : 576-581. 1 January 2001

Circulation Research

The gut microbiome in hypertension: recent advances and future perspectives.
Avery, E.G., Bartolomaeus, H., Maifeld, A., Marko, L., Wiig, H., Wilck, N., Rosshart, S.P., Forslund, S.K. and Muller, D.N.
Circulation Research 128 (7): 934-950. 2 April 2021

CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia.
Przybyl, L., Haase, N., Golic, M., Rugor, J., Solano, M.E., Arck, P.C., Gauster, M., Huppertz, B., Emontzpohl, C., Stoppe, C., Bernhagen, J., Leng, L., Bucala, R., Schulz, H., Heuser, A., Weedon-Fekjær, S., Johnsen, G.M., Peetz, D., Luft, F.C., Staff, A.C., Müller, D.N., Dechend, R. and Herse, F.
Circulation Research 119 (1): 55-68. 24 June 2016

Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Henke, N., Schmidt-Ullrich, R., Dechend, R., Park, J.K., Qadri, F., Wellner, M., Obst, M., Gross, V., Dietz, R., Luft, F.C., Scheidereit, C. and Mueller, D.N.
Circulation Research 101 (3): 268-276. 3 August 2007

Complement activation in angiotensin II-induced organ damage.
Shagdarsuren, E., Wellner, M., Braesen, J.H., Park, J.K., Fiebeler, A., Henke, N., Dechend, R., Gratze, P., Luft, F.C. and Mueller, D.N.
Circulation Research 97 (7): 716-724. 18 August 2005

Local angiotensin II generation in the rat heart: role of renin uptake.
Mueller, D.N., Fischli, W., Clozel, J.P., Hilgers, K.F., Bohlender, J., Menard, J., Busjahn, A., Ganten, D. and Luft, F.C.
Circulation Research 82 (1): 13-20. 9 January 1998

Clinical Hemorheology and Microcirculation

Effect of cytochrome P450-dependent epoxyeicosanoids on Ristocetin-induced thrombocyte aggregation.
Jung, F., Schulz, C., Blaschke, F., Muller, D.N., Mrowietz, C., Franke, R.P., Lendlein, A. and Schunck, W.H.
Clinical Hemorheology and Microcirculation 52 (2-4): 403-416. 2012

Clinical Journal of the American Society of Nephrology

New approaches to pathogenesis and management of hypertension.
Ritz, E., Krum, H., Schlaich, M., Whitbourn, R., Sobotka, P.A., Sadowski, J., Bartus, K., Kapelak, B., Walton, A., Sievert, H., Thambar, S., Abraham, W.T., Esler, M., Wang, Y., Tsun, Z., Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J.K., Beck, F.X., Mueller, D.N., Derer, W., Goss, J., Ziomber, A., Dietsch, P., Wagner, H., van Rooijen, N., Kurtz, A., Hilgers, K.F., Alitalo, K., Eckardt, K.U., Luft, F.C., Kerjaschki, D. and Titze, J.
Clinical Journal of the American Society of Nephrology 4 (12): 1886-1891. December 2009

Direct renin inhibition with aliskiren in hypertension and target organ damage.
Mueller, D.N. and Luft, F.C.
Clinical Journal of the American Society of Nephrology 1 (2): 221-228. March 2006

Clinical Nephrology

Angiotensin II and endothelin induce inflammation and thereby promote hypertension-induced end-organ damage.
Mueller, D.N., Fiebeler, A., Park, J.K., Dechend, R. and Luft, F.C.
Clinical Nephrology 60 (Suppl.1): S2-S12. July 2003

Clinical Science

Hypertensive retinopathy in a transgenic angiotensin-based model.
Reichhart, N., Haase, N., Crespo-Garcia, S., Skosyrski, S., Herrspiegel, C., Kociok, N., Fuchshofer, R., Dillinger, A., Poglitsch, M., Müller, D.N., Joussen, A.M., Luft, F.C., Dechend, R. and Strauß, O.
Clinical Science 130 (13): 1075-1088. 1 July 2016

Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation.
Kankuri, E., Mervaala, E.E., Storvik, M., Ahola, A.M.J., Levijoki, J., Müller, D.N., Finckenberg, P. and Mervaala, E.M.
Clinical Science 128 (11): 735-747. 1 June 2015

The direct renin inhibitor aliskiren improves vascular remodelling in transgenic rats harbouring human renin and angiotensinogen genes.
Savoia, C., Arrabito, E., Parente, R., Sada, L., Madaro, L., Nicoletti, C., Zezza, L., Alonzo, A., Rubattu, S., Michelini, S., Muller, D.N. and Volpe, M.
Clinical Science 125 (4): 183-189. 1 August 2013

Angiogenic growth factors in the diagnosis and prediction of pre-eclampsia.
Verlohren, S., Stepan, H. and Dechend, R.
Clinical Science 122 (2): 43-52. 1 January 2012

Clinical and Translational Science

Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease.
van Kraaij, S.J.W., Pereira, D.R., Smal, B., Summo, L., Konkel, A., Lossie, J., Busjahn, A., Grammatopoulos, T.N., Klaassen, E., Fischer, R., Schunck, W.H., Gal, P. and Moerland, M.
Clinical and Translational Science 16 (7): 1258-1271. July 2023

Contributions to Nephrology

Angiotensin-induced inflammation and vascular injury.
Mueller, D.N., Dechend, R., Fiebeler, A., Park, J.K., Haller, H. and Luft, F.C.
Contributions to Nephrology 135 : 138-152. April 2001

Current Allergy and Asthma Reports

Role of "western diet" in inflammatory autoimmune diseases.
Manzel, A., Muller, D.N., Hafler, D.A., Erdman, S.E., Linker, R.A. and Kleinewietfeld, M.
Current Allergy and Asthma Reports 14 (1): 404. January 2014

Current Hypertension Reports

Treating hypertension in pregnancy.
Schlembach, D., Homuth, V. and Dechend, R.
Current Hypertension Reports 17 : 63. July 2015

Renin receptor blockade: a better strategy for renal protection than Renin-Angiotensin system inhibition?
Mueller, D.N. and Luft, F.C.
Current Hypertension Reports 10 (5): 405-409. October 2008

Current Opinion in Nephrology and Hypertension

Immune-related effects in hypertension and target-organ damage.
Mueller, D.N., Kvakan, H. and Luft, F.C.
Current Opinion in Nephrology and Hypertension 20 (2): 113-117. March 2011

Aldosterone, mineralocorticoid receptors, and vascular inflammation.
Fiebeler, A., Mueller, D.N., Shagdarsuren, E. and Luft, F.C.
Current Opinion in Nephrology and Hypertension 16 (2): 134-142. March 2007

Cytokine

Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: a study by the Tumor Bank Ovarian Cancer (TOC).
Rohr, I., Braicu, E.I., En-Nia, A., Heinrich, M., Richter, R., Chekerov, R., Dechend, R., Heidecke, H., Dragun, D., Schäfer, R., Gorny, X., Lindquist, J., Brandt, S., Sehouli, J. and Mertens, P.R.
Cytokine 85 : 157-164. September 2016

Deutsche Medizinische Wochenschrift

Aktueller Standard der Blutdruckmessung - Stellungnahme der Deutschen Hochdruckliga e. V. DHL® - Deutsche Gesellschaft für Hypertonie und Prävention [Actual standard of blood pressure measurement - statement of the German High Blood Pressure League].
Eckert, S., Ott, C., Büchner, N., Dechend, R., Lüders, S., Mengden, T. and Sanner, B.
Deutsche Medizinische Wochenschrift 144 (21): 1522-1527. October 2019

Praxisleitlinien fuer Heimblutdruckmessung [Practice guidelines for home blood pressure measurement].
Mengden, T., Dechend, R., Lueders, S., Eckert, S., Tholl, U. and Sanner, B.
Deutsche Medizinische Wochenschrift 136 (46): 2374-2377. November 2011

Hypertonie und Schwangerschaft [Hypertension and pregnancy].
Homuth, V., Derer, W. and Dechend, R.
Deutsche Medizinische Wochenschrift 134 (5): 195-200. January 2009

Development

A Grhl2-dependent gene network controls trophoblast branching morphogenesis.
Walentin, K., Hinze, C., Werth, M., Haase, N., Varma, S., Morell, R., Aue, A., Pötschke, E., Warburton, D., Qiu, A., Barasch, J., Purfürst, B., Dieterich, C., Popova, E., Bader, M., Dechend, R., Staff, A.C., Yurtdas, Z.Y., Kilic, E. and Schmidt-Ott, K.M.
Development 142 (6): 1125-1136. 15 March 2015

Developmental Cell

The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution.
Taylor, D.M., Aronow, B.J., Tan, K., Bernt, K., Salomonis, N., Greene, C.S., Frolova, A., Henrickson, S.E., Wells, A., Pei, L., Jaiswal, J.K., Whitsett, J., Hamilton, K.E., MacParland, S.A., Kelsen, J., Heuckeroth, R.O., Potter, S.S., Vella, L.A., Terry, N.A., Ghanem, L.R., Kennedy, B.C., Helbig, I., Sullivan, K.E., Castelo-Soccio, L., Kreigstein, A., Herse, F., Nawijn, M.C., Koppelman, G.H., Haendel, M., Harris, N.L., Rokita, J.L., Zhang, Y., Regev, A., Rozenblatt-Rosen, O., Rood, J.E., Tickle, T.L, Vento-Tormo, R., Alimohamed, S., Lek, M., Mar, J.C., Loomes, K.M., Barrett, D.M., Uapinyoying, P., Beggs, A.H., Agrawal, P.B., Chen, Y.W., Muir, A.B., Garmire, L.X., Snapper, S.B., Nazarian, J., Seeholzer, S.H., Fazelinia, H., Singh, L.N., Faryabi, R.B., Raman, P., Dawany, N., Xie, H.M., Devkota, B., Diskin, S.J., Anderson, S.A., Rappaport, E.F., Peranteau, W., Wikenheiser-Brokamp, K.A., Teichmann, S., Wallace, D., Peng, T., Ding, Y.Y., Kim, M.S., Xing, Y., Kong, S.W., Bönnemann, C.G., Mandl, K.D. and White, P.S.
Developmental Cell 49 (1): 10-29. 8 April 2019

Diabetes, Stoffwechsel und Herz

Präeklampsie, das Herz und der Blutdruck [Preeclampsia, the heart and the blood pressure].
Dechend, R.
Diabetes, Stoffwechsel und Herz 23 (5): 292-293. 1 October 2014

Sind ACE-Hemmer besser als Angiotensin-Rezeptor-Blocker fuer Diabetiker? Ueberraschende Ergebnisse aus einer großen Metaanalyse [Are ACE inhibitors better than angiotensin receptor blockers for diabetics? Surprising results from a large-scale meta-analysis].
Derer, W. and Dechend, R.
Diabetes, Stoffwechsel und Herz 23 (3): 174-175. 20 June 2014

Aktuelle Aspekte der Herzinsuffizienz [Current aspects of heart failure].
Dechend, R.
Diabetes, Stoffwechsel und Herz 22 (3): 182-183. 20 June 2013

Die Bedeutung der Herzfrequenz fuer die Hypertonie [The significance of heart rate for hypertension].
Dechend, R.
Diabetes, Stoffwechsel und Herz 22 (1): 50-51. 20 February 2013

Hypertonie und Depression : Zusammenhaenge und Probleme des gemeinsamen ­Auftretens [Hypertension and depression : context and issues of joint appearances].
Dechend, R.
Diabetes, Stoffwechsel und Herz 21 (5): 334-335. October 2012

Diabetologia

Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring-the heart as a target for fetal programming in rats.
Schütte, T., Kedziora, S.M., Haase, N., Herse, F., Alenina, N., Müller, D.N., Bader, M., Schupp, M., Dechend, R., Golic, M. and Kräker, K.
Diabetologia 64 (12): 2829-2842. December 2021

The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.
Reichhart, N., Crespo-Garcia, S., Haase, N., Golic, M., Skosyrski, S., Rübsam, A., Herrspiegel, C., Kociok, N., Alenina, N., Bader, M., Dechend, R., Strauss, O. and Joussen, A.M.
Diabetologia 60 (1): 202-211. January 2017

Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants.
Yung, H.W., Alaes-Katjavivi, P., Jones, C.J.P., El-Bacha, T., Golic, M., Staff, A.C. and Burton, G.J.
Diabetologia 59 (10): 2240-2250. October 2016

Dialyse aktuell

Der Einfluss der Mikrobiota auf den Blutdruck : Wie Darmbakterien Bluthochdruck und Organschäden beeinflussen.
Wilck, N.
Dialyse aktuell 24 (9): 360-366. November 2020

Drug Discovery Today: Disease Mechanisms

Complement activation in vascular remodeling and organ damage.
Shagdarsuren, E., Mueller, D.N., Weber, C. and Zernecke, A.
Drug Discovery Today: Disease Mechanisms 5 (3-4): e299-e306. December 2008

ESC Heart Failure

Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure.
Zweck, E., Karschnia, M., Scheiber, D., Heidecke, H., Dechend, R., Barthuber, C., Kaufmann, S., Kelm, M., Roden, M., Westenfeld, R., Szendrödi, J. and Boege, F.
ESC Heart Failure 10 (2): 1258-1269. April 2023

Nitric oxide metabolites: associations with cardiovascular biomarkers and clinical parameters in patients with HFpEF.
Piatek, K., Feuerstein, A., Zach, V., Rozados da Conceicao, C., Beblo, A., Belyavskiy, E., Pieske-Kraigher, E., Krannich, A., Schwedhelm, E., Hinz, S., Pieske, B. and Edelmann, F.
ESC Heart Failure 9 (6): 3961-3972. December 2022

Environment International

Exposure to perfluoroalkyl substances and blood pressure in pregnancy among 1436 women from the Odense Child Cohort.
Birukov, A., Andersen, L.B., Andersen, M.S., Nielsen, J.H., Nielsen, F.g, Kyhl, H.B., Jørgensen, J.S., Grandjean, P., Dechend, R. and Jensen, T.K.
Environment International 151 : 106442. June 2021

Enzyme and Microbial Technology

A simple fluorescent labeling technique to study virus adsorption in Newcastle disease virus infected cells.
Balogh, A., Pap, M., Marko, L., Koloszar, I., Csatary, L.K. and Szeberenyi, J.
Enzyme and Microbial Technology 49 (3): 255-259. 10 August 2011

European Heart Journal

Autoantibodies against the chemokine receptor 3 predict cardiovascular risk.
Müller, F.S., Aherrahrou, Z., Grasshoff, H., Heidorn, M.W., Humrich, J.Y., Johanson, L., Aherrahrou, R., Reinberger, T., Schulz, A., Ten Cate, V., Robles, A.P., Koeck, T., Rapp, S., Lange, T., Brachaczek, L., Luebber, F., Erdmann, J., Heidecke, H., Schulze-Forster, K., Dechend, R., Lackner, K.J., Pfeiffer, N., Ghaemi Kerahrodi, J., Tüscher, O., Schwarting, A., Strauch, K., Münzel, T., Prochaska, J.H., Riemekasten, G. and Wild, P.S.
European Heart Journal 44 (47): 4935-4949. 14 December 2023

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism.
Haghikia, A., Zimmermann, F., Schumann, P., Jasina, A., Roessler, J., Schmidt, D., Heinze, P., Kaisler, J., Nageswaran, V., Aigner, A., Ceglarek, U., Cineus, R., Hegazy, A.N., van der Vorst, E.P.C., Döring, Y., Strauch, C.M., Nemet, I., Tremaroli, V., Dwibedi, C., Kränkel, N., Leistner, D.M., Heimesaat, M.M., Bereswill, S., Rauch, G., Seeland, U., Soehnlein, O., Müller, D.N., Gold, R., Bäckhed, F., Hazen, S.L., Haghikia, A. and Landmesser, U.
European Heart Journal 43 (6): ehab644. 7 February 2022

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap: results from the prospective translational OPTICO-ACS study.
Leistner, D.M., Kränkel, N., Meteva, D., Abdelwahed, Y.S., Seppelt, C., Stähli, B.E., Rai, H., Skurk, C., Lauten, A., Mochmann, H.C., Fröhlich, G., Rauch-Kröhnert, U., Flores, E., Riedel, M., Sieronski, L., Kia, S., Strässler, E., Haghikia, A., Dirks, F., Steiner, J. K., Mueller, D.N., Volk, H.D., Klotsche, J., Joner, M., Libby, P. and Landmesser, U.
European Heart Journal 41 (37): 3549-3560. 20 October 2020

European Journal of Clinical Investigation

Long-term clopidogrel administration following severe coronary injury reduces proliferation and inflammation via inhibition of nuclear factor-κB and activator protein 1 activation in pigs.
Pels, K., Schwimmbeck, P.L., Rosenthal, P., Loddenkemper, C., Dang-Heine, C., Rauch, U., Martens, H., Schultheiss, H.P., Dechend, R. and Deiner, C.
European Journal of Clinical Investigation 39 (3): 174-182. March 2009

European Journal of Immunology

The role of the gut microbiota and microbial metabolites in neuroinflammation.
Haase, S., Wilck, N., Haghikia, A., Gold, R., Mueller, D.N. and Linker, R.A.
European Journal of Immunology 50 (12): 1863-1870. December 2020

European Journal of Internal Medicine

State of the art approach to managing angina and ischemia: tailoring treatment to the evidence.
Manolis, A.J., Boden, W.E., Collins, P., Dechend, R., Kallistratos, M.S., Lopez Sendon, J., Poulimenos, L.E., Ambrosio, G. and Rosano, G.
European Journal of Internal Medicine 92 : 40-47. October 2021

The ESC 2019 CCS guidelines: have we left our patients and scientific evidence behind?
Manolis, A.J., Kallistratos, M.S., Poulimenos, L.Ε., Ambrosio, G., Dechend, R., Lopez-Sendon, J., Rosano, G. and Collins, P.
European Journal of Internal Medicine 72 : 5-8. February 2020

Impact of stable angina on health status and quality of life perception of currently treated patients. The BRIDGE 2 survey.
Manolis, A.J., Ambrosio, G., Collins, P., Dechend, R., Lopez-Sendon, J., Pegoraro, V. and Camm, A.J.
European Journal of Internal Medicine 70 : 60-67. November 2019

European Journal of Pharmacology

Aptamer BC 007 - a broad spectrum neutralizer of pathogenic autoantibodies against G-protein-coupled receptors.
Haberland, A., Holtzhauer, M., Schlichtiger, A., Bartel, S., Schimke, I., Mueller, J., Dandel, M., Luppa, P.B. and Wallukat, G.
European Journal of Pharmacology 789 : 37-45. 15 October 2016

European Journal of Preventive Cardiology

Risk prediction of maternal cardiovascular disease one year after hypertensive pregnancy complications or gestational diabetes mellitus.
Moe, K., Sugulle, M., Dechend, R. and Staff, A.C.
European Journal of Preventive Cardiology 27 (12): 1273-1283. 1 August 2020

Experimental Neurology

High salt drives Th17 responses in experimental autoimmune encephalomyelitis without impacting myeloid dendritic cells.
Jörg, S., Kissel, J., Manzel, A., Kleinewietfeld, M., Haghikia, A., Gold, R., Müller, D.N. and Linker, R.A.
Experimental Neurology 279 : 212-222. May 2016

Experimental and Translational Stroke Medicine

Report on the 5'th scientific meeting of the "Verein zur Foerderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th - Oct. 27th, 2013.
Linker, R.A., Magnus, T., Korn, T., Kleinschnitz, C. and Meuth, S.G.
Experimental and Translational Stroke Medicine 5 (1): 15. 11 December 2013

Exploration of Medicine

Placental CD4(+) T cells from preeclamptic patients cause autoantibodies to the angiotensin II type I receptor and hypertension in a pregnant rat model of preeclampsia.
Reeve, K.E., Deer, E., Amaral, L.M., Cornelius, D.C., Herrock, O., Harmon, A.C., Campbell, N., Fitzgerald, S., Ibrahim, T., Wallukat, G., Dechend, R. and LaMarca, B.
Exploration of Medicine 3 : 99-111. 25 February 2022

FASEB Journal

Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular K(V) currents and predisposes to ventricular arrhythmia.
David, J.P., Lisewski, U., Crump, S.M., Jepps, T.A., Bocksteins, E., Wilck, N., Lossie, J., Roepke, T.K., Schmitt, N. and Abbott, G.W.
FASEB Journal 33 (2): 2537-2552. February 2019

Cellular and molecular mechanisms of tissue protection by lipophilic calcium channel blockers.
Menne, J., Park, J.K., Agrawal, R., Lindschau, C., Kielstein, J.T., Kirsch, T., Marx, A., Muller, D., Bahlmann, F.H., Meier, M., Bode-Böger, S.M., Haller, H. and Fliser, D.
FASEB Journal 20 (7): 994-996. May 2006

Aspirin inhibits NF-kappa B and protects from angiotensin II-induced organ damage.
Mueller, D.N., Heissmeyer, V., Dechend, R., Hampich, F., Park, J.K., Fiebeler, A., Shagdarsuren, E., Theuer, J., Elger, M., Pilz, B., Breu, V., Schroer, K., Ganten, D., Dietz, R., Haller, H., Scheidereit, C. and Luft, F.C.
FASEB Journal 15 : 1822-1824. 1 January 2001

Farmaco

Piperidine renin inhibitors: from leads to drug candidates.
Maerki, H.P., Binggeli, A., Bittner, B., Bohner-Lang, V., Breu, V., Bur, D., Coassolo, P.H., Clozel, J.P., D'Arcy, A., Doebeli, H., Fischli, W., Funk, C.H., Foricher, J., Giller, T., Grueninger, F., Guenzi, A., Gueller, R., Hartung, T., Hirth, G., Jenny, C.H., Kansy, M., Klinkhammer, U., Lave, T., Lohri, B., Luft, F.C., Mervaala, E.M., Mueller, D.N., Mueller, M., Montavon, F., Oefner, C.H., Qiu, C., Reichel, A., Sanwald-Ducray, P., Scalone, M., Schleimer, M., Schmid, R., Treiber, H., Treiber, A., Valdenaire, O., Vieira, E., Waldmeier, P., Wiegand-Chou, R., Wilhelm, M., Wostl, W., Zell, M. and Zell, R.
Farmaco 56 (1-2): 21-27. 1 March 2001

Frontiers in Bioscience

Regulatory antibodies against GPCR in women ten years after early-onset preeclampsia.
Birukov, A., Muijsers, H.E.C., Heidecke, H., Drost, J.T., Cunnigham, M.W., Kraker, K., Haase, N., Frolova, A., Müller, D.N., Herse, F., Maas, A.H.E.M. and Dechend, R.
Frontiers in Bioscience 24 : 1462-1476. 1 June 2019

Anti-β1-adrenoreceptor auto-antibodies in elderly heart failure patients.
Trippel, T.D., Mueller, D.N., Obradovic, D., Edelmann, F., Tahirovic, E., Wilck, N., Riemekasten, G., Dragun, D., Busjahn, A., Heidecke, H., Junker, J., Pieske, B., Dungen, H.D. and Dechend, R.
Frontiers in Bioscience 24 : 1037-1049. 1 March 2019

The (pro)renin receptor and the mystic HRP -Is there a role in cardiovascular disease?
Maschke, U. and Mueller, D.N.
Frontiers in Bioscience 2 : 1250-1253. 1 June 2010

Frontiers in Bioscience-Landmark

Soluble (pro)renin receptor in elderly chronic heart failure patients.
Obradovic, D., Loncar, G., Radenovic, S., Tahirovic, E., Heidecke, H., Schulze-Forster, K., Muller, D., Busjahn, A., Buttner, P., Veskovic, J., Zdravkovic, M., Li, H., Li, S., Savkovic, V., Pieske, B., Dungen, H.D. and Dechend, R.
Frontiers in Bioscience-Landmark 25 : 1839-1853. 1 June 2020

Frontiers in Cell and Developmental Biology

CD39 abrogates platelet-derived factors induced IL-1β expression in the human placenta.
Forstner, D., Guettler, J., Brugger, B.A., Lyssy, F., Neuper, L., Daxboeck, C., Cvirn, G., Fuchs, J., Kraeker, K., Frolova, A., Valdes, D.S., Stern, C., Hirschmugl, B., Fluhr, H., Wadsack, C., Huppertz, B., Nonn, O., Herse, F. and Gauster, M.
Frontiers in Cell and Developmental Biology 11 : 1183793. 2023

Frontiers in Endocrinology

Cardiovascular programming during and after diabetic pregnancy: role of placental dysfunction and IUGR.
Langmia, I.M., Kräker, K., Weiss, S.E., Haase, N., Schütte, T., Herse, F. and Dechend, R.
Frontiers in Endocrinology 10 : 215. April 2019

Human sFLT1 leads to severe changes in placental differentiation and vascularization in a transgenic hsFLT1/rtTA FGR mouse model.
Vogtmann, R., Kühnel, E., Dicke, N., Verkaik-Schakel, R.N., Plösch, T., Schorle, H., Stojanovska, V., Herse, F., Köninger, A., Kimmig, R., Winterhager, E. and Gellhaus, A.
Frontiers in Endocrinology 10 : 165. March 2019

Continuous blood glucose monitoring reveals enormous circadian variations in pregnant diabetic rats.
Golic, M., Kräker, K., Fischer, C., Alenina, N., Haase, N., Herse, F., Schütte, T., Henrich, W., Müller, D.N., Busjahn, A., Bader, M. and Dechend, R.
Frontiers in Endocrinology 9 : 271. 29 May 2018

Autophagy and the (pro)renin receptor.
Binger, K.J. and Muller, D.N.
Frontiers in Endocrinology 4 : 155. 21 October 2013

Frontiers in Immunology

Amelioration of endotoxemia by a synthetic analog of Omega-3 epoxyeicosanoids.
Shikuma, A., Kami, D., Maeda, R., Suzuki, Y., Sano, A., Taya, T., Ogata, T., Konkel, A., Matoba, S., Schunck, W.H. and Gojo, S.
Frontiers in Immunology 13 : 825171. 24 February 2022

Acute atherosis lesions at the fetal-maternal border: current knowledge and implications for maternal cardiovascular health.
Pitz Jacobsen, D., Fjeldstad, H.E., Johnsen, G.M., Fosheim, I.K., Moe, K., Alnæs-Katjavivi, P., Dechend, R., Sugulle, M. and Staff, A.C.
Frontiers in Immunology 12 : 791606. 14 December 2021

Propionic acid rescues high-fat diet enhanced immunopathology in autoimmunity via effects on Th17 responses.
Haase, S., Mäurer, J., Duscha, A., Lee, D.H., Balogh, A., Gold, R., Müller, D.N., Haghikia, A. and Linker, R.A.
Frontiers in Immunology 12 : 701626. 1 June 2021

Interplay of Na(+) balance and immunobiology of dendritic cells.
Neubert, P., Schröder, A., Müller, D.N. and Jantsch, J.
Frontiers in Immunology 10 : 599. March 2019

Metabolic, mental and immunological effects of normoxic and hypoxic training in multiple sclerosis patients: a pilot study.
Mähler, A., Balogh, A., Csizmadia, I., Klug, L., Kleinewietfeld, M., Steiniger, J., Šušnjar, U., Müller, D.N., Boschmann, M. and Paul, F.
Frontiers in Immunology 9 : 2819. November 2018

Frontiers in Neurology

A comprehensive monitoring study on electrocardiographic assessments and cardiac events after fingolimod first dose - possible predictors of cardiac outcomes.
Limmroth, V., Ziemssen, T., Kleiter, I., Wagner, B., Schmidt, S., Lassek, C., Baier-Ebert, M., Wendt, G., Dechend, R. and Haverkamp, W.
Frontiers in Neurology 11 : 818. 12 August 2020

Frontiers in Physiology

Aging affects K(V)7 channels and perivascular adipose tissue-mediated vascular tone.
Wang, Y., Yildiz, F., Struve, A., Kassmann, M., Markó, L., Köhler, M.B., Luft, F.C., Gollasch, M. and Tsvetkov, D.
Frontiers in Physiology 12 : 749709. 26 November 2021

Macrophages in homeostatic immune function.
Jantsch, J., Binger, K.J., Müller, D.N. and Titze, J.
Frontiers in Physiology 5 : 146. May 2014

Gender Medicine

Angiotensin II type 1 autoantibody induced hypertension during pregnancy is associated with renal endothelial dysfunction.
Parrish, M.R., Ryan, M.J., Glover, P., Brewer, J., Ray, L., Dechend, R., Martin, J.N. and Lamarca, B.B.
Gender Medicine 8 (3): 184-188. June 2011

Health and Quality of Life Outcomes

Converting PROMIS®-29 v2.0 profile data to SF-36 physical and mental component summary scores in patients with cardiovascular disorders.
Liegl, G., Fischer, F.H., Martin, C.N., Rönnefarth, M., Blumrich, A., Ahmadi, M., Boldt, L.H., Eckardt, K.U., Endres, M., Edelmann, F., Gerhardt, H., Grittner, U., Haghikia, A., Hübner, N., Landmesser, U., Leistner, D., Mai, K., Kollmus-Heege, J., Müller, D.N., Nolte, C.H., Piper, S.K., Schmidt-Ott, K.M., Pischon, T., Rattan, S., Rohrpasser-Napierkowski, Ira, Schönrath, K., Schulz-Menger, J., Schweizerhof, O., Spranger, J., Weber, J.E., Witzenrath, M., Schmidt, S. and Rose, M.
Health and Quality of Life Outcomes 22 (1): 64. 15 August 2024

Herz

Darm-Herz-Achse: Wie Darmbakterien kardiovaskuläre Erkrankungen beeinflussen [Gut-heart axis: how gut bacteria influence cardiovascular diseases].
Bartolomaeus, H., McParland, V. and Wilck, N.
Herz 45 (2): 134-141. April 2020

Histochemistry and Cell Biology

Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-α in a gestational age-dependent manner.
Prokesch, A., Blaschitz, A., Bauer, T., Moser, G., Hiden, U., Zadora, J., Dechend, R., Herse, F. and Gauster, M.
Histochemistry and Cell Biology 147 (6): 695-705. June 2017

Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast.
Siwetz, M., Sundl, M., Kolb, D., Hiden, U., Herse, F., Huppertz, B. and Gauster, M.
Histochemistry and Cell Biology 143 (6): 565-574. June 2015

Hypertension

Prospects for leveraging the microbiota as medicine for hypertension.
Durgan, D.J., Zubcevic, J., Vijay-Kumar, M., Yang, T., Manandhar, I., Aryal, S., Muralitharan, R.R., Li, H.B., Li, Y., Abais-Battad, J.M., Pluznick, J.L., Muller, D.N., Marques, F.Z. and Joe, B.
Hypertension 81 (5): 951-963. May 2024

Sodium as an important regulator of immunometabolism.
Miyauchi, H., Geisberger, S., Luft, F.C., Wilck, N., Stegbauer, J., Wiig, H., Dechend, R., Jantsch, J., Kleinewietfeld, M., Kempa, S. and Mueller, D.N.
Hypertension 81 (3): 426-435. March 2024

Genetic engineering of lymphangiogenesis in skin does not affect blood pressure in mouse models of salt-sensitive hypertension.
Thowsen, I.M., Reikvam, T., Skogstrand, T., Samuelsson, A.M., Mueller, D.N., Tenstad, O., Alitalo, K., Karlsen, T. and Wiig, H.
Hypertension 79 (11): 2451-2462. November 2022

Loss of endothelial cytochrome P450 reductase induces vascular dysfunction in mice.
Malacarne, P.F., Ratiu, C., Gajos-Draus, A., Müller, N., Lopez, M., Pflüger-Müller, B., Ding, X., Warwick, T., Oo, J., Siragusa, M., Angioni, C., Günther, S., Weigert, A., Geißlinger, G., Lütjohann, D., Schunck, W.H., Fleming, I., Brandes, R.P. and Rezende, F.
Hypertension 79 (6): 1216-1226. June 2022

Effect of sunitinib treatment on skin sodium accumulation in patients with renal cancer: a pilot study.
Markó, L., Dörr, A., Linz, P., van den Meiracker, A.H., Garrelds, I.M., Kuehne, T., Dechend, R., Danser, A.H.J., Flörcken, A. and Müller, D.N.
Hypertension 79 (5): e103-e105. May 2022

Hypertension in pregnancy: diagnosis, blood pressure goals, and pharmacotherapy: a scientific statement from the American Heart Association.
Garovic, V.D., Dechend, R., Easterling, T., Karumanchi, S.A., McMurtry Baird, S., Magee, L.A., Rana, S., Vermunt, J.V. and August, P.
Hypertension 79 (2): e21-e41. February 2022

Circulating maternal sFLT1 (soluble fms-like tyrosine kinase-1) is sufficient to impair spiral arterial remodeling in a preeclampsia mouse model.
Vogtmann, R., Heupel, J., Herse, F., Matin, M., Hagmann, H., Bendix, I., Kräker, K., Dechend, R., Winterhager, E., Kimmig, R., Köninger, A. and Gellhaus, A.
Hypertension 78 (4): 1067-1079. September 2021

Maternal angiotensin increases placental leptin in early gestation via an alternative renin-angiotensin system pathway: suggesting a link to preeclampsia.
Nonn, O., Fischer, C., Geisberger, S., El-Heliebi, A., Kroneis, T., Forstner, D., Desoye, G., Staff, A.C., Sugulle, M., Dechend, R., Pecks, U., Kollmann, M., Stern, C., Cartwright, J.E., Whitley, G.S., Thilaganathan, B., Wadsack, C., Huppertz, B., Herse, F. and Gauster, M.
Hypertension 77 (5): 1723-1736. May 2021

Intrauterine exposure to diabetic milieu does not induce diabetes and obesity in male adulthood in a novel rat model.
Schütte, T., Kedziora, S.M., Haase, N., Herse, F., Busjahn, A., Birukov, A., Alenina, N., Müller, D.N., Bader, M., Schupp, M., Dechend, R., Kräker, K. and Golic, M.
Hypertension 77 (1): 202-215. January 2021

Will postnatal renin-angiotensin system blockade improve long-term maternal cardiovascular health after preeclampsia?
Staff, A.C. and Dechend, R.
Hypertension 76 (6): 1704-1706. December 2020

Blood pressure and angiogenic markers in pregnancy: contributors to pregnancy-induced hypertension and offspring cardiovascular risk.
Birukov, A.., Herse, F., Nielsen, J.H., Kyhl, H.B., Golic, M., Kräker, K., Haase, N., Busjahn, A., Bruun, S., Jensen, B.L., Müller, D.N., Jensen, T.K., Christesen, H.T., Andersen, M.S., Jørgensen, J.S., Dechend, R. and Andersen, L.B.
Hypertension 76 (3): 901-909. September 2020

Multiplex analysis of circulating maternal cardiovascular biomarkers comparing preeclampsia subtypes.
Lekva, T., Sugulle, M., Moe, K., Redman, C., Dechend, R. and Staff, A.C.
Hypertension 75 (6): 1513-1522. June 2020

Statins reverse postpartum cardiovascular dysfunction in a rat model of preeclampsia.
Kräker, K., O'Driscoll, J.M., Schütte, T., Herse, F., Patey, O., Golic, M., Geisberger, S., Verlohren, S., Birukov, A., Heuser, A., Mueller, D.N., Thilaganathan, B., Dechend, R. and Haase, N.
Hypertension 75 (1): 202-210. January 2020

Aldosterone, salt, and potassium intakes as predictors of pregnancy outcome, including preeclampsia.
Birukov, A., Andersen, L.B., Herse, F., Rakova, N., Kitlen, G., Kyhl, H.B., Golic, M., Haase, N., Kräker, K., Müller, D.N., Jørgensen, J.S., Andersen, M.S., Dechend, R. and Jensen, B.L.
Hypertension 74 (2): 391-398. August 2019

Precarious symbiosis between host and microbiome in cardiovascular health.
Bartolomaeus, H., Markó, L., Wilck, N., Luft, F.C., Forslund, S.K. and Muller, D.N.
Hypertension 73 (5): 926-935. May 2019

Classical cardiovascular risk markers in pregnancy and associations to uteroplacental acute atherosis.
Moe, K., Alnaes-Katjavivi, P., Storvold, G.L., Sugulle, M., Johnsen, G.M., Redman, C.W.G., Dechend, R. and Staff, A.C.S.
Hypertension 72 (3): 695-702. September 2018

Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats.
Morgan, H.L., Butler, E., Ritchie, S., Herse, F., Dechend, R., Beattie, E., McBride, M.W. and Graham, D.
Hypertension 72 (1): 208-218. July 2018

Preeclampsia: What does the brain tell us? Can we blame the eclampsia risk on a malperfused placenta?
Staff, A.C. and Dechend, R.
Hypertension 72 (1): 65-67. July 2018

Cystathionine γ-lyase-produced hydrogen sulfide controls endothelial NO bioavailability and blood pressure.
Szijártó, I.A., Markó, L., Filipovic, M.R., Miljkovic, J.L., Tabeling, C., Tsvetkov, D., Wang, N., Rabelo, L.A., Witzenrath, M., Diedrich, A., Tank, J., Akahoshi, N., Kamata, S., Ishii, I. and Gollasch, M.
Hypertension 71 (6): 1210-1217. June 2018

Diabetes mellitus in pregnancy leads to growth restriction and epigenetic modification of the Srebf2 gene in rat fetuses.
Golic, M., Stojanovska, V., Bendix, I., Wehner, A., Herse, F., Haase, N., Kräker, K., Fischer, C., Alenina, N., Bader, M., Schütte, T., Schuchardt, M., van der Giet, M., Henrich, W., Muller, D.N., Felderhoff-Müser, U., Scherjon, S., Plösch, T. and Dechend, R.
Hypertension 71 (5): 911-920. May 2018

Salt sensitivity of angiogenesis inhibition-induced blood pressure rise: role of interstitial sodium accumulation?
Lankhorst, S., Severs, D., Markó, L., Rakova, N., Titze, J., Müller, D.N., Danser, A.H.J. and van den Meiracker, A.H.
Hypertension 69 (5): 919-926. May 2017

High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph.
Nikpey, E., Karlsen, T.V., Rakova, N., Titze, J.M., Tenstad, O. and Wiig, H.
Hypertension 69 (4): 660-668. April 2017

Agonistic autoantibodies to the angiotensin II type 1 receptor enhance angiotensin II-induced renal vascular sensitivity and reduce renal function during pregnancy.
Cunningham, M.W., Williams, J.M., Amaral, L., Usry, N., Wallukat, G., Dechend, R. and LaMarca, B.
Hypertension 68 (5): 1308-1313. November 2016

Tumor necrosis factor-α, uterine natural killer cells, and pregnancy.
Golic, M., Luft, F.C. and Dechend, R.
Hypertension 68 (5): 1108-1109. November 2016

Natural killer cell reduction and uteroplacental vasculopathy.
Golic, M., Haase, N., Herse, F., Wehner, A., Vercruysse, L., Pijnenborg, R., Balogh, A., Saether, P.C., Dissen, E., Luft, F.C., Przybyl, L., Park, J.K., Alnaes-Katjavivi, P., Staff, A.C., Verlohren, S., Henrich, W., Muller, D.N. and Dechend, R.
Hypertension 68 (4): 964-973. October 2016

Regulatory T cells ameliorate intrauterine growth retardation in a transgenic rat model for preeclampsia.
Przybyl, L., Ibrahim, T., Haase, N., Golic, M., Rugor, J., Luft, F.C., Bendix, I., Serdar, M., Wallukat, G., Staff, A.C., Müller, D.N., Hünig, T., Felderhoff-Müser, U., Herse, F., LaMarca, B. and Dechend, R.
Hypertension 65 (6): 1298-1306. June 2015

Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.
Markó, L., Henke, N., Park, J.K., Spallek, B., Qadri, F., Balogh, A., Apel, I.J., Oravecz-Wilson, K.I., Choi, M., Przybyl, L., Binger, K.J., Haase, N., Wilck, N., Heuser, A., Fokuhl, V., Ruland, J., Lucas, P.C., McAllister-Lucas, L.M., Luft, F.C., Dechend, R. and Müller, D.N.
Hypertension 64 (5): 1032-1039. November 2014

Disproportional decrease in office blood pressure compared with 24-hour ambulatory blood pressure with antihypertensive treatment: dependency on pretreatment blood pressure levels.
Schmieder, R.E., Schmidt, S.T., Riemer, T., Dechend, R., Hagedorn, I., Senges, J., Messerli, F.H. and Zeymer, U.
Hypertension 64 (5): 1067-1072. November 2014

Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis.
Pulgar, V.M., Yamaleyeva, L.M., Varagic, J., McGee, C.M., Bader, M., Dechend, R., Howlett, A.C. and Brosnihan, K.B.
Hypertension 64 (3): 619-625. September 2014

Administration of interleukin-17 soluble receptor C suppresses T(H)17 cells, oxidative stress, and hypertension in response to placental ischemia during pregnancy.
Cornelius, D.C., Hogg, J.P., Scott, J., Wallace, K., Herse, F., Moseley, J., Wallukat, G., Dechend, R. and Lamarca, B.
Hypertension 62 (6): 1068-1073. December 2013

Amyloid-β peptides activate α1-adrenergic cardiovascular receptors.
Haase, N., Herse, F., Spallek, B., Haase, H., Morano, I., Qadri, F., Szijártó, I.A., Rohm, I., Yilmaz, A., Warrington, J.P., Ryan, M.J., Gollasch, M., Müller, D.N., Dechend, R. and Wallukat, G.
Hypertension 62 (5): 966-972. November 2013

Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type I receptor autoantibody-enhanced renal and blood pressure response during pregnancy.
Brewer, J., Liu, R., Lu, Y., Scott, J., Wallace, K., Wallukat, G., Moseley, J., Herse, F., Dechend, R., Martin, J.N. and Lamarca, B.
Hypertension 62 (5): 886-892. November 2013

(23)Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients.
Kopp, C., Linz, P., Dahlmann, A., Hammon, M., Jantsch, J., Müller, D.N., Schmieder, R.E., Cavallaro, A., Eckardt, K.U., Uder, M., Luft, F.C. and Titze, J.
Hypertension 61 (3): 635-640. March 2013

Single nucleotide polymorphisms in G protein signaling pathway genes in preeclampsia.
Kvehaugen, A.S., Melien, O., Holmen, O.L., Laivuori, H., Oian, P., Andersgaard, A.B., Dechend, R. and Staff, A.C.
Hypertension 61 (3): 655-661. March 2013

Interferon-gamma signaling inhibition ameliorates angiotensin II-induced cardiac damage.
Marko, L., Kvakan, H., Park, J.K., Qadri, F., Spallek, B., Binger, K.J., Bowman, E.P., Kleinewietfeld, M., Fokuhl, V., Dechend, R. and Mueller, D.N.
Hypertension 60 (6): 1430-1436. December 2012

CD19+CD5+ cells as indicators of preeclampsia.
Jensen, F., Wallukat, G., Herse, F., Budner, O., El-Mousleh, T., Costa, S.D., Dechend, R. and Zenclussen, A.C.
Hypertension 59 (4): 861-868. April 2012

Cardiovascular biomarker midregional proatrial natriuretic peptide during and after preeclamptic pregnancies.
Sugulle, M., Herse, F., Hering, L., Mockel, M., Dechend, R. and Staff, A.C.
Hypertension 59 (2): 395-401. February 2012

Placenta messages to the mother: not just debris.
Dechend, R. and Staff, A.C.
Hypertension 59 (2): 191-193. February 2012

23Na magnetic resonance imaging of tissue sodium.
Kopp, C., Linz, P., Wachsmuth, L., Dahlmann, A., Horbach, T., Schoefl, C., Renz, W., Santoro, D., Niendorf, T., Mueller, D.N., Neininger, M., Cavallaro, A., Eckardt, K.U., Schmieder, R.E., Luft, F.C., Uder, M. and Titze, J.
Hypertension 59 (1): 167-172. January 2012

Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy.
Finckenberg, P., Eriksson, O., Baumann, M., Merasto, S., Lalowski, M.M., Levijoki, J., Haasio, K., Kytoe, V., Mueller, D.N., Luft, F.C., Oresic, M. and Mervaala, E.
Hypertension 59 (1): 76-84. 2012

Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur?
Batenburg, W.W., Lu, X., Leijten, F., Maschke, U., Mueller, D.N. and Danser, A.H.J.
Hypertension 58 (6): 1111-1119. December 2011

Adipose tissue-derived soluble fms-like tyrosine kinase 1 is an obesity-relevant endogenous paracrine adipokine.
Herse, F., Fain, J.N., Janke, J., Engeli, S., Kuhn, C., Frey, N., Weich, H.A., Bergmann, A., Kappert, K., Karumanchi, S.A., Luft, F.C., Mueller, D.N., Staff, A.C. and Dechend, R.
Hypertension 58 (1): 37-42. July 2011

Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats.
Wenzel, K., Rajakumar, A., Haase, H., Geusens, N., Hubner, N., Schulz, H., Brewer, J., Roberts, L., Hubel, C.A., Herse, F., Hering, L., Qadri, F., Lindschau, C., Wallukat, G., Pijnenborg, R., Heidecke, H., Riemekasten, G., Luft, F.C., Muller, D.N., Lamarca, B. and Dechend, R.
Hypertension 58 (1): 77-84. July 2011

Endothelial function and circulating biomarkers are disturbed in women and children after preeclampsia.
Kvehaugen, A.S., Dechend, R., Ramstad, H.B., Troisi, R., Fugelseth, D. and Staff, A.C.
Hypertension 58 (1): 63-69. July 2011

Hypertension in response to placental ischemia during pregnancy: role of B lymphocytes.
Lamarca, B., Wallace, K., Herse, F., Wallukat, G., Martin, J.N., Weimer, A. and Dechend, R.
Hypertension 57 (4): 865-871. April 2011

Learning from the placenta: acute atherosis and vascular remodeling in preeclampsia-novel aspects for atherosclerosis and future cardiovascular health.
Staff, A.C., Dechend, R. and Pijnenborg, R.
Hypertension 56 (6): 1026-1034. December 2010

Effects of circulating and local uteroplacental angiotensin II in rat pregnancy.
Hering, L., Herse, F., Geusens, N., Verlohren, S., Wenzel, K., Staff, A.C., Brosnihan, K.B., Huppertz, B., Luft, F.C., Mueller, D.N., Pijnenborg, R., Cartwright, J.E. and Dechend, R.
Hypertension 56 (2): 311-318. August 2010

Inhibition of trophoblast-induced spiral artery remodeling reduces placental perfusion in rat pregnancy.
Verlohren, S., Geusens, N., Morton, J., Verhaegen, I., Hering, L., Herse, F., Dudenhausen, J.W., Mueller, D.N., Luft, F.C., Cartwright, J.E., Davidge, S.T., Pijnenborg, R. and Dechend, R.
Hypertension 56 (2): 304-310. August 2010

Response to Blood pressure control: a facelift for macrophages?
Titze, J., Mueller, D.N. and Luft, F.C.
Hypertension 56 (2): E24. August 2010

Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats.
Machnik, A., Dahlmann, A., Kopp, C., Goss, J., Wagner, H., van Rooijen, N., Eckardt, K.U., Mueller, D.N., Park, J.K., Luft, F.C., Kerjaschki, D. and Titze, J.
Hypertension 55 (3): 755-761. March 2010

Increased angiotensin II in the mesometrial triangle of a transgenic rat model of preeclampsia.
Brosnihan, K.B., Hering, L., Dechend, R., Chappell, M.C. and Herse, F.
Hypertension 55 (2): 562-566. February 2010

Metabolomics in angiotensin II-induced cardiac hypertrophy.
Mervaala, E., Biala, A., Merasto, S., Lempiaeinen, J., Mattila, I., Martonen, E., Eriksson, O., Louhelainen, M., Finckenberg, P., Kaheinen, P., Mueller, D.N., Luft, F.C., Lapatto, R. and Oresic, M.
Hypertension 55 (2): 508-515. February 2010

Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats - role of endothelin-1.
Lamarca, B., Parrish, M., Ray, L.F., Murphy, S.R., Roberts, L., Glover, P., Wallukat, G., Wenzel, K., Cockrell, K., Martin, J.N., Ryan, M.J. and Dechend, R.
Hypertension 54 (4): 905-909. October 2009

Immunology in hypertension, preeclampsia, and target-organ damage.
Verlohren, S., Mueller, D.N., Luft, F.C. and Dechend, R.
Hypertension 54 (3): 439-443. September 2009

Growth arrest specific protein 6 participates in DOCA-induced target-organ damage.
Park, J.K., Theuer, S., Kirsch, T., Lindschau, C., Klinge, U., Heuser, A., Plehm, R., Todiras, M., Carmeliet, P., Haller, H., Luft, F.C., Mueller, D.N. and Fiebeler, A.
Hypertension 54 (2): 359-364. August 2009

Circulating and placental growth-differentiation factor 15 in preeclampsia and in pregnancy complicated by diabetes mellitus.
Sugulle, M., Dechend, R., Herse, F., Weedon-Fekjaer, M.S., Johnsen, G.M., Brosnihan, K.B., Anton, L., Luft, F.C., Wollert, K.C., Kempf, T. and Staff, A.C.
Hypertension 54 (1): 106-112. July 2009

Energy metabolism in human renin-gene transgenic rats. Does renin contribute to obesity?
Gratze, P., Boschmann, M., Dechend, R., Qadri, F., Malchow, J., Graeske, S., Engeli, S., Janke, J., Springer, J., Contrepas, A., Plehm, R., Klaus, S., Nguyen, G., Luft, F.C. and Mueller, D.N.
Hypertension 53 (3): 516-523. March 2009

Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study.
Herse, F., Verlohren, S., Wenzel, K., Pape, J., Mueller, D.N., Modrow, S., Wallukat, G., Luft, F.C., Redman, C.W. and Dechend, R.
Hypertension 53 (2): 393-398. February 2009

Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mREN-2)27 rats.
Feldman, D.L., Jin, L., Xuan, H., Contrepas, A., Zhou, Y., Webb, R.L., Mueller, D.N., Feldt, S., Cumin, F., Maniara, W., Persohn, E., Schuetz, H., Jan Danser, A.H. and Nguyen, G.
Hypertension 52 (1): 130-136. July 2008

Glucocorticoid-related signaling effects in vascular smooth muscle cells.
Molnar, G.A., Lindschau, C., Dubrovska, G., Mertens, P.R., Kirsch, T., Quinkler, M., Gollasch, M., Wresche, S., Luft, F.C., Mueller, D.N. and Fiebeler, A.
Hypertension 51 (5): 1372-1378. May 2008

(Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in goldblatt rats.
Mueller, D.N., Klanke, B., Feldt, S., Cordasic, N., Hartner, A., Schmieder, R.E., Luft, F.C. and Hilgers, K.F.
Hypertension 51 (3): 676-681. March 2008

Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide.
Feldt, S., Batenburg, W.W., Mazak, I., Maschke, U., Wellner, M., Kvakan, H., Dechend, R., Fiebeler, A., Burckle, C., Contrepas, A., Danser, A.H., Bader, M., Nguyen, G., Luft, F.C. and Mueller, D.N.
Hypertension 51 (3): 682-688. March 2008

Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension.
Fischer, R., Dechend, R., Qadri, F., Markovic, M., Feldt, S., Herse, F., Park, J.K., Gapelyuk, A., Schwarz, I., Zacharzowsky, U.B., Plehm, R., Safak, E., Heuser, A., Schirdewan, A., Luft, F.C., Schunck, W.H. and Mueller, D.N.
Hypertension 51 (2): 540-546. February 2008

Trophoblasts reduce the vascular smooth muscle cell proatherogenic response.
Hering, L., Herse, F., Verlohren, S., Park, J.K., Wellner, M., Qadri, F., Pijnenborg, R., Staff, A.C., Huppertz, B., Mueller, D.N., Luft, F.C. and Dechend, R.
Hypertension 51 (2): 554-559. February 2008

Uterine vascular function in a transgenic preeclampsia rat model.
Verlohren, S., Niehoff, M., Hering, L., Geusens, N., Herse, F., Tintu, A.N., Plagemann, A., le Noble, F., Pijnenborg, R., Mueller, D.N., Luft, F.C., Dudenhausen, J.W., Gollasch, M. and Dechend, R.
Hypertension 51 (2): 547-553. February 2008

Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia.
Herse, F., Dechend, R., Harsem, N.K., Wallukat, G., Janke, J., Qadri, F., Hering, L., Mueller, D.N., Luft, F.C. and Staff, A.C.
Hypertension 49 (3): 604-611. March 2007

p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage.
Park, J.K., Fischer, R., Dechend, R., Shagdarsuren, E., Gapeljuk, A., Wellner, M., Meiners, S., Gratze, P., Al-Saadi, N., Feldt, S., Fiebeler, A., Madwed, J.B., Schirdewan, A., Haller, H., Luft, F.C. and Mueller, D.N.
Hypertension 49 (3): 481-489. March 2007

Elevated blood pressure and heart rate in human renin receptor transgenic rats.
Burckle, C.A., Danser, A.H.J., Mueller, D.N., Garrelds, I.M., Gasc, J.M., Popova, E., Plehm, R., Peters, J., Bader, M. and Nguyen, G.
Hypertension 47 (3): 552-556. March 2006

Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats.
Pilz, B., Shagdarsuren, E., Wellner, M., Fiebeler, A., Dechend, R., Gratze, P., Meiners, S., Feldman, D.L., Webb, R.L., Garrelds, I.M., Danser, A.H.J., Luft, F.C. and Mueller, D.N.
Hypertension 46 (3): 569-576. 15 August 2005

Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia.
Dechend, R., Gratze, P., Wallukat, G., Shagdarsuren, E., Plehm, R., Braesen, J.H., Fiebeler, A., Schneider, W., Caluwaerts, S., Vercruysse, L., Pijnenborg, R., Luft, F.C. and Mueller, D.N.
Hypertension 45 (4): 742-746. 1 January 2005

Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage.
Muller, D.N., Mullally, A., Dechend, R., Park, J.K., Fiebeler, A., Pilz, B., Loeffler, B.M., Blum-Kaelin, D., Masur, S., Dehmlow, H., Aebi, J.D., Haller, H. and Luft, F.C.
Hypertension 40 (6): 840-846. December 2002

P450-dependent arachidonic acid metabolism and angiotensin II-induced renal damage.
Kaergel, E., Mueller, D.N., Honeck, H., Theuer, J., Shagdarsuren, E., Mullally, A., Luft, F.C. and Schunck, W.H.
Hypertension 40 (3): 273-279. 1 September 2002

Lacidipine inhibits adhesion molecule and oxidase expression independent of blood pressure reduction in angiotensin-induced vascular injury.
Park, J.K., Fiebeler, A., Muller, D.N., Mervaala, E.M.A., Dechend, R., Abou-Rebyeh, F., Luft, F.C. and Haller, H.
Hypertension 39 : 685-689. 1 January 2002

Renin uptake by the endothelium mediates vascular angiotensin formation.
Hilgers, K.F., Veelken, R., Mueller, D.N., Kohler, H., Hartner, A., Botkin, S.R., Stumpf, C., Schmieder, R.E. and Gomez, R.A.
Hypertension 38 : 243-248. August 2001

Endothelial dysfunction and salt-sensitive hypertension in spontaneously diabetic Goto-Kakizaki rats.
Cheng, Z.J., Vaskonen, T., Tikkanen, I., Nurminen, K., Ruskoaho, H., Vapaatalo, H., Muller, D., Park, J.K., Luft, F.C. and Mervaala, E.M.A.
Hypertension 37 : 433-439. 1 January 2001

Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Mervaala, E.M.A., Cheng, Z.J., Tikkanen, I., Lapatto, R., Nurminen, K., Vapaatalo, H., Mueller, D.N., Fiebeler, A., Ganten, U., Ganten, D. and Luft, F.C.
Hypertension 37 (2): 414-418. 1 January 2001

Mineralocorticoid receptor affects AP-1 and nuclear factor-kappa B activation in angiotensin II-induced cardiac injury.
Fiebeler, A., Schmidt, F., Mueller, D.N., Park, J.K., Dechend, R., Bieringer, M., Shagdarsuren, E., Breu, V., Haller, H. and Luft, F.C.
Hypertension 37 : 787-793. 1 January 2001

Effect of Bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
Muller, D.N., Mervaala, E.M.A., Schmidt, F., Park, J.K., Dechend, R., Genersch, E., Breu, V., Loeffler, B.M., Ganten, D., Schneider, W., Haller, H. and Luft, F.C.
Hypertension 36 (2): 282-290. 1 August 2000

Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Mervaalo, E., Mueller, D.N., Schmidt, F., Park, J.K., Gross, V., Bader, M., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35 (2): 587-594. 1 February 2000

Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
Mervaala, E., Mueller, D.N., Park, J.K., Dechend, R., Schmidt, F., Fiebeler, A., Bieringer, M., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35 (1): 360-366. 1 January 2000

NF-kappaB Inhibition Ameliorates Angiotensin II-Induced Inflammatory Damage in Rats.
Muller, D.N., Dechend, R., Mervaala, E.M.A., Park, J.K., Schmidt, F., Fiebeler, A., Theuer, J., Breu, V., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 35 (1): 193-201. 1 January 2000

Effects of human prorenin in rats transgenic for human angiotensinogen.
Mueller, D.N., Hilgers, K.F., Mathews, S., Breu, V., Fischli, W., Uhlmann, R. and Luft, F.C.
Hypertension 33 : 312-317. 1 January 1999

Hypertension-induced end-organ damage - A new transgenic approach to an old problem.
Luft, F.C., Mervaala, E., Mueller, D.N., Gross, V., Schmidt, F., Park, J.K., Schmitz, C., Lippoldt, A., Breu, V., Dechend, R., Dragun, D., Schneider, W., Ganten, D. and Haller, H.
Hypertension 33 : 212-218. 1 January 1999

Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension.
Mervaala, E.M.A., Mueller, D.N., Park, J.K., Schmidt, F., Loehn, M., Breu, V., Dragun, D., Ganten, D., Haller, H. and Luft, F.C.
Hypertension 33 : 389-395. 1 January 1999

Angiotensinases restrict locally generated angiotensin II to the blood vessel wall.
Hilgers, K.F., Bingener, E., Stumpf, C., Muller, D.N., Schmieder, R.E. and Veelken, R.
Hypertension 31 : 368-372. 1 January 1998

Vascular angiotensin converting enzyme expression regulates local angiotensin II.
Mueller, D.N., Bohlender, J., Hilgers, K.F., Dragun, D., Costerousse, O., Menard, J. and Luft, F.C.
Hypertension 29 (1 Pt 1): 98-104. 1 January 1997

Effects of human renin in the vasculature of rats transgenic for human angiotensinogen.
Mueller, D.N., Hilgers, K.F., Bohlender, J., Lippoldt, A., Wagner, J., Fischli, W., Ganten, D., Mann, J.F.E. and Luft, F.C.
Hypertension 26 : 272-278. 1 January 1995

Hypertension Research

Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure.
Biala, A., Martonen, E., Kaheinen, P., Levijoki, J., Finckenberg, P., Merasto, S., Louhelainen, M., Mueller, D.N., Luft, F.C. and Mervaala, E.
Hypertension Research 33 (10): 1004-1011. October 2010

Hypertension in Pregnancy

Increased placental sFlt-1 but unchanged PlGF expression in late-onset preeclampsia.
Ehrlich, L., Hoeller, A., Golic, M., Herse, F., Perschel, F.H., Henrich, W., Dechend, R., Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36 (2): 175-185. May 2017

Placental expression of sFlt-1 and PlGF in early preeclampsia vs. early IUGR vs. age-matched healthy pregnancies.
Hoeller, A., Ehrlich, L., Golic, M., Herse, F., Perschel, F.H., Siwetz, M., Henrich, W., Dechend, R., Huppertz, B. and Verlohren, S.
Hypertension in Pregnancy 36 (2): 151-160. May 2017

Prediction of preeclampsia with angiogenic biomarkers. Results from the prospective Odense Child Cohort.
Andersen, L.B., Dechend, R., Jørgensen, J.S., Luef, B.M., Nielsen, J., Barington, T. and Christesen, H.T.
Hypertension in Pregnancy 35 (3): 405-419. August 2016

IL-10 supplementation increases Tregs and decreases hypertension in the RUPP rat model of preeclampsia.
Harmon, A., Cornelius, D., Amaral, L., Paige, A., Herse, F., Ibrahim, T., Wallukat, G., Faulkner, J., Moseley, J., Dechend, R. and LaMarca, B.
Hypertension in Pregnancy 34 (3): 291-306. August 2015

Immunity

Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine.
Haghikia, A., Jörg, S., Duscha, A., Berg, J., Manzel, A., Waschbisch, A., Hammer, A., Lee, D.H., May, C., Wilck, N., Balogh, A., Ostermann, A.I., Schebb, N.H., Akkad, D.A., Grohme, D.A., Kleinewietfeld, M., Kempa, S., Thöne, J., Demir, S., Müller, D.N., Gold, R. and Linker, R.A.
Immunity 43 (4): 817-829. 20 October 2015

Immunology

Impacts of microbiome metabolites on immune regulation and autoimmunity.
Haase, S., Haghikia, A., Wilck, N., Müller, D.N. and Linker, R.A.
Immunology 154 (2): 230-238. June 2018

International Congress Series

Time course of changes in cardiac magnetic field mapping after myocardial infarction in rats.
Fischer, R., Gapelyuk, A., Wessel, N., Gruner, K., Gruner, A., Mueller, D., Dietz, R. and Schirdewan, A.
International Congress Series 1300 (1300): 484-487. June 2007

International Journal of Cardiology

Medical treatment of stable angina: a tailored therapeutic approach.
Manolis, A.J., Poulimenos, L.E., Ambrosio, G., Kallistratos, M.S., Lopez-Sendon, J., Dechend, R., Mancia, G. and Camm, A.J.
International Journal of Cardiology 220 : 445-453. 1 October 2016

1-Year outcomes of hypertension management in 13,000 outpatients under practice conditions: Prospective 3A registry.
Zeymer, U., Dechend, R., Riemer, T., Kaiser, E., Senges, J., Pittrow, D. and Schmieder, R.E.
International Journal of Cardiology 176 (3): 589-594. 20 October 2014

Ambulatory blood pressure monitoring: Is it mandatory for blood pressure control in treated hypertensive patients? Prospective observational study.
Lehmann, M.V., Zeymer, U., Dechend, R., Kaiser, E., Hagedorn, I., Deeg, E., Senges, J. and Schmieder, R.E.
International Journal of Cardiology 168 (3): 2255-2263. 3 October 2013

International Journal of Cerebrovascular Disease and Stroke

AT1-AA infusion during pregnancy impairs CBF autoregulation postpartum.
Campbell, N., Strong, L., Fang, X., Border, J.J., Herrock, O., Turner, T., Deer, E., Amaral, L., Dechend, R., Roman, R.J. and LaMarca, B.
International Journal of Cerebrovascular Disease and Stroke 6 (1): 154. 17 July 2023

International Journal of Clinical Practice

Aliskiren for the treatment of essential hypertension under real-life practice conditions: design and baseline data of the prospective 3A registry.
Zeymer, U., Dechend, R., Deeg, E., Kaiser, E., Senges, J., Pittrow, D. and Schmieder, R.
International Journal of Clinical Practice 66 (3): 251-261. March 2012

International Journal of Interferon, Cytokine and Mediator Research

Hypertension in response to IL-6 during pregnancy: role of AT1-receptor activation.
Lamarca, B., Speed, J., Ray, L.F., Cockrell, K., Wallukat, G., Dechend, R. and Granger, J.
International Journal of Interferon, Cytokine and Mediator Research 2011 (3): 65-70. 3 November 2011

International Journal of Molecular Sciences

The effect of renal denervation on T cells in patients with resistant hypertension.
Kantauskaite, M., Vonend, O., Yakoub, M., Heilmann, P., Maifeld, A., Minko, P., Schimmöller, L., Antoch, G., Müller, D.N., Schmidt, C., Duvnjak, B., Zierhut, U., Potthoff, S.A., Rump, L.C., Fischer, J.C. and Stegbauer, J.
International Journal of Molecular Sciences 24 (3): 2493. 27 January 2023

Placental transcriptome profiling in subtypes of diabetic pregnancies is strongly confounded by fetal sex.
Kedziora, S.M., Obermayer, B., Sugulle, M., Herse, F., Kräker, K., Haase, N., Langmia, I.M., Müller, D.N., Staff, A.C., Beule, D. and Dechend, R.
International Journal of Molecular Sciences 23 (23): 15388. 6 December 2022

Candesartan does not activate PPAR(γ) and its target genes in early gestation trophoblasts.
Neuper, L., Kummer, D., Forstner, D., Guettler, J., Ghaffari-Tabrizi-Wizsy, N., Fischer, C., Juch, H., Nonn, O. and Gauster, M.
International Journal of Molecular Sciences 23 (20): 12326. October 2022

In vivo inhibition of TRPC6 by SH045 attenuates renal fibrosis in a New Zealand Obese (NZO) mouse model of metabolic syndrome.
Zheng, Z., Xu, Y., Krügel, U., Schaefer, M., Grune, T., Nürnberg, B., Köhler, M.B., Gollasch, M., Tsvetkov, D. and Marko, L.
International Journal of Molecular Sciences 23 (12): 6870. 20 June 2022

Kidney injury caused by preeclamptic pregnancy recovers postpartum in a transgenic rat model.
Kedziora, S.M., Kräker, K., Markó, L., Binder, J., Sugulle, M., Gauster, M., Mueller, D.N., Dechend, R., Haase, N. and Herse, F.
International Journal of Molecular Sciences 22 (7): 3762. 5 April 2021

Speckle tracking echocardiography: new ways of translational approaches in preeclampsia to detect cardiovascular dysfunction.
Kräker, K., Schütte, T., O'Driscoll, J., Birukov, A., Patey, O., Herse, F., Mueller, D.N., Thilaganathan, B., Haase, N. and Dechend, R.
International Journal of Molecular Sciences 21 (3): 1162. 10 February 2020

Placental CX3CL1 is deregulated by angiotensin II and contributes to a pro-inflammatory trophoblast-monocyte interaction.
Nonn, O., Güttler, J., Forstner, D., Maninger, S., Zadora, J., Balogh, A., Frolova, A., Glasner, A., Herse, F. and Gauster, M.
International Journal of Molecular Sciences 20 (3): 641. 2 February 2019

The effect of low-dose proteasome inhibition on pre-existing atherosclerosis in LDL receptor-deficient mice.
Wilck, N., Fechner, M., Dan, C., Stangl, V., Stangl, K. and Ludwig, A.
International Journal of Molecular Sciences 18 (4): 781. 7 April 2017

Internist

Ernährung und Hypertonie : Worauf man neben der medikamentösen Therapie achten sollte [Nutrition and hypertension : what one should pay attention to in addition to the pharmaceutical treatment].
McParland, V. and Wilck, N.
Internist 62 (3): 269-276. March 2021

Antikoagulation bei Patienten mit chronischer Niereninsuffizienz: Empfehlungen der Arbeitsgemeinschaft "Herz-Niere" der Deutschen Gesellschaft für Kardiologie - Herz- und Kreislaufforschung und der Deutschen Gesellschaft für Nephrologie [Anticoagulation in patients with chronic kidney disease : Recommendations from the working group "Heart-Kidney" of the German Cardiac Society and the German Society of Nephrology].
Schlieper, G., Schwenger, V., Remppis, A., Keller, T., Dechend, R., Massberg, S., Baldus, S., Weinreich, T., Hetzel, G., Floege, J., Mahfoud, F. and Fliser, D.
Internist 58 (5): 512-521. May 2017

JACC: Cardiovascular Imaging

Myocardial evaluation of post-preeclamptic women by CMR: is early risk stratification possible?
Birukov, A., Wiesemann, S., Golic, M., Balogh, A., Marko, L., Rakova, N., Wilck, N., Blaszczyk, E., Lim, C., Weiss, S., Kräker, K., Haase, N., Frolova, A., Jørgensen, J.S., Daub, S., Mueller, D.N., Herse, F., Schulz-Menger, J. and Dechend, R.
JACC: Cardiovascular Imaging 13 (5): 1291-1293. May 2020

JCI Insight

The longevity gene mIndy (I'm Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms.
Willmes, D.M., Daniels, M., Kurzbach, A., Lieske, S., Bechmann, N., Schumann, T., Henke, C., El-Agroudy, N.N., Da Costa Goncalves, A.C., Peitzsch, M., Hofmann, A., Kanczkowski, W., Kräker, K., Müller, D.N., Morawietz, H., Deussen, A., Wagner, M., El-Armouche, A., Helfand, S.L., Bornstein, S.R., de Cabo, R., Bernier, M., Eisenhofer, G., Tank, J., Jordan, J. and Birkenfeld, A.L.
JCI Insight 6 (2): 136083. 25 January 2021

Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.
Wilck, N., Markó, L., Balogh, A., Kräker, K., Herse, F., Bartolomaeus, H., Szijártó, I.A., Gollasch, M., Reichhart, N., Strauss, O., Heuser, A., Brockschnieder, D., Kretschmer, A., Lesche, R., Sohler, F., Stasch, J.P., Sandner, P., Luft, F., Müller, D.N., Dechend, R. and Haase, N.
JCI Insight 3 (4): e96006. 22 February 2018

Journal of Alzheimer's Disease

Antibodies to signaling molecules and receptors in Alzheimer's disease are associated with psychomotor slowing, depression, and poor visuospatial function.
Giil, L.M., Vedeler, C.A., Kristoffersen, E.K., Nordrehaug, J.E., Heidecke, H., Dechend, R., Schulze-Forster, K., Muller, D.N., von Goetze, V.S., Cabral-Marques, O., Riemekasten, G., Vogelsang, P., Nygaard, S., Lund, A. and Aarsland, D.
Journal of Alzheimer's Disease 59 (3): 929-939. 29 July 2017

Journal of Biological Chemistry

Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids.
Kranrod, J., Konkel, A., Valencia, R., Darwesh, A., Fischer, R., Schunck, W.H. and Seubert, J.M.
Journal of Biological Chemistry 300 (6): 107372. June 2024

Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of omega-3 fatty acids.
Arnold, C., Markovic, M., Blossey, K., Wallukat, G., Fischer, R., Dechend, R., Konkel, A., von Schacky, C., Luft, F.C., Mueller, D.N., Rothe, M. and Schunck, W.H.
Journal of Biological Chemistry 285 (43): 32720-32733. 22 October 2010

Journal of Cellular Biochemistry

Placental-specific overexpression of sFlt-1 alters trophoblast differentiation and nutrient transporter expression in an IUGR mouse model.
Kuehnel, E., Kleff, V., Stojanovska, V., Kaiser, S., Waldschuetz, R., Herse, F., Ploesch, T., Winterhager, E. and Gellhaus, A.
Journal of Cellular Biochemistry 118 (6): 1316-1329. June 2017

Journal of Cerebral Blood Flow and Metabolism

Stroke-prone salt-sensitive spontaneously hypertensive rats show higher susceptibility to spreading depolarization (SD) and altered hemodynamic responses to SD.
Kang, E.J., Prager, O., Lublinsky, S., Oliveira-Ferreira, A.I., Reiffurth, C., Major, S., Mueller, D.N., Friedman, A. and Dreier, J.P.
Journal of Cerebral Blood Flow and Metabolism 43 (2): 210-230. February 2023

Journal of Clinical Endocrinology and Metabolism

Cardiac phenotype and tissue sodium content in adolescents with defects in the melanocortin system.
Puder, L., Roth, S., Krabusch, P., Wiegand, S., Opitz, R., Bald, M., Flück, C., Schulz, E., Voss, E., Markó, L., Linz, P., Berger, F., Müller, D.N., Kuehne, T., Litt, M.J., Cone, R.D., Kühnen, P. and Kelm, M.
Journal of Clinical Endocrinology and Metabolism 106 (9): 2606–2616. September 2021

A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is up-regulated in hypoxia and preeclampsia.
Thomas, C.P., Andrews, J.I., Raikwar, N.S., Kelley, E.A., Herse, F., Dechend, R., Golos, T.G. and Liu, K.Z.
Journal of Clinical Endocrinology and Metabolism 94 (7): 2524-2530. July 2009

Journal of Clinical Hypertension

Benefits and risks of aliskiren treatment in patients with type 2 diabetes: analyses of the 3A registry.
Kistner, I., Zeymer, U., Dechend, R., Hagedorn, I., Riemer, T., Bramlage, P., Pittrow, D., Senges, J. and Schmieder, R.E.
Journal of Clinical Hypertension 18 (10): 1045-1053. October 2016

Two-year outcomes of patients treated with aliskiren under clinical practice conditions: non-interventional prospective study.
Zeymer, U., Dechend, R., Riemer, T., Deeg, E., Senges, J., Pittrow, D. and Schmieder, R.
Journal of Clinical Hypertension 18 (7): 647-654. July 2016

Guideline adherence in cardiovascular risk assessment and analysis in 15,000 hypertensive German patients in real life: results of the Prospective 3A Registry.
Dechend, R., Kaiser, E., Derer, W., Deeg, E., Busjahn, A., Schmieder, R.E. and Zeymer, U.
Journal of Clinical Hypertension 14 (8): 496-501. August 2012

Journal of Clinical Investigation

RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase, N., Foster, D.J., Cunningham, M.W., Bercher, J., Nguyen, T., Shulga-Morskaya, S., Milstein, S., Shaikh, S., Rollins, J., Golic, M., Herse, F., Kräker, K., Bendix, I., Serdar, M., Napieczynska, H., Heuser, A., Gellhaus, A., Thiele, K., Wallukat, G., Müller, D.N., LaMarca, B. and Dechend, R.
Journal of Clinical Investigation 130 (6): 2928-2942. 1 June 2020

SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
Voelkl, J., Luong, T.T., Tuffaha, R., Musculus, K., Auer, T., Lian, X., Daniel, C., Zickler, D., Boehme, B., Sacherer, M., Metzler, B., Kuhl, D., Gollasch, M., Amann, K., Müller, D.N., Pieske, B., Lang, F. and Alesutan, I.
Journal of Clinical Investigation 128 (7): 3024-3040. 2 July 2018

High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
Kitada, K., Daub, S., Zhang, Y., Klein, J. D., Nakano, D., Pedchenko, T., Lantier, L., LaRocque, L.M., Marton, A., Neubert, P., Schröder, A., Rakova, N., Jantsch, J., Dikalova, A.E., Dikalov, S.I., Harrison, D.G., Müller, D.N., Nishiyama, A., Rauh, M., Harris, R. C., Luft, F.C., Wassermann, D.H., Sands, J.M. and Titze, J.
Journal of Clinical Investigation 127 (5): 1944-1959. 1 May 2017

Increased salt consumption induces body water conservation and decreases fluid intake.
Rakova, N., Kitada, K., Lerchl, K., Dahlmann, A., Birukov, A., Daub, S., Kopp, C., Pedchenko, T., Zhang, Y., Beck, L., Johannes, B., Marton, A., Müller, D.N., Rauh, M., Luft, F.C. and Titze, J.
Journal of Clinical Investigation 127 (5): 1932-1943. 1 May 2017

High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.
Binger, K.J., Gebhardt, M., Heinig, M., Rintisch, C., Schroeder, A., Neuhofer, W., Hilgers, K., Manzel, A., Schwartz, C., Kleinewietfeld, M., Voelkl, J., Schatz, V., Linker, R.A., Lang, F., Voehringer, D., Wright, M.D., Hubner, N., Dechend, R., Jantsch, J., Titze, J. and Müller, D.N.
Journal of Clinical Investigation 125 (11): 4223-4238. 2 November 2015

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure.
Wiig, H., Schröder, A., Neuhofer, W., Jantsch, J., Kopp, C., Karlsen, T.V., Boschmann, M., Goss, J., Bry, M., Rakova, N., Dahlmann, A., Brenner, S., Tenstad, O., Nurmi, H., Mervaala, E., Wagner, H., Beck, F.X., Müller, D.N., Kerjaschki, D., Luft, F.C., Harrison, D.G., Alitalo, K. and Titze, J.
Journal of Clinical Investigation 123 (7): 2803-2815. 1 July 2013

Journal of Clinical Medicine

Age of red cells for transfusion and outcomes in patients with ARDS.
Graw, J.A., Bünger, V., Materne, L.A., Krannich, A., Balzer, F., Francis, R.C.E., Pruß, A., Spies, C.D., Kuebler, W.M., Weber-Carstens, S., Menk, M. and Hunsicker, O.
Journal of Clinical Medicine 11 (1): 245. 4 January 2022

Tissue sodium content and arterial hypertension in obese adolescents.
Roth, S., Markó, L., Birukov, A., Hennemuth, A., Kühnen, P., Jones, A., Ghorbani, N., Linz, P., Müller, D.N., Wiegand, S., Berger, F., Kuehne, T. and Kelm, M.
Journal of Clinical Medicine 8 (12): 2036. 21 November 2019

Journal of Hepatocellular Carcinoma

Decision-tree models indicative of microvascular invasion on MRI predict survival in patients with hepatocellular carcinoma following tumor ablation.
Schmidt, R., Hamm, C.A., Rueger, C., Xu, H., He, Y., Gottwald, L.A., Gebauer, B. and Savic, L.J.
Journal of Hepatocellular Carcinoma 11 : 1279-1293. 3 July 2024

Journal of Human Hypertension

The impact of age on the benefits and risks of aliskiren treatment: analyses of the 3A registry.
Friedrich, S., Zeymer, U., Dechend, R., Hagedorn, I., Riemer, T., Zemmrich, C., Bramlage, P., Pittrow, D., Senges, J. and Schmieder, R.E.
Journal of Human Hypertension 29 (5): 316-323. May 2015

Journal of Hypertension

Elevated blood pressure in pregnant women with gestational diabetes according to the WHO criteria: importance of overweight.
Birukov, A., Glintborg, D., Schulze, M.B., Jensen, T.K., Kuxhaus, O., Andersen, L.B., Kräker, K., Polemiti, E., Jensen, B.L., Jørgensen, J.S., Dechend, R. and Andersen, M.S.
Journal of Hypertension 40 (8): 1614-1623. August 2022

High-sensitivity cardiac troponin I in women with a history of early-onset preeclampsia.
Muijsers, H.E.C., Westermann, D., Birukov, A., van der Heijden, O.W.H., Drost, J.T., Kräker, K., Haase, N., Müller, D.N., Herse, F., Maas, A.H.E M, Dechend, R., Zeller, T. and Roeleveld, N.
Journal of Hypertension 38 (10): 1948-1954. October 2020

Angiotensin II responsiveness after preeclampsia: translational data from an experimental rat model and early-onset human preeclampsia.
van der Graaf, A.M., Toering, T.J., van der Wiel, M.W.K., Frenay, A.R.S., Wallukat, G., Dechend, R., Navis, G., Groen, H., Lely, A.T. and Faas, M.M.
Journal of Hypertension 35 (12): 2468-2478. December 2017

Inhibition of the renin-angiotensin-aldosterone system: is there room for dual blockade in the cardiorenal continuum?
Volpe, M., Danser, A.H., Menard, J., Waeber, B., Mueller, D.N., Maggioni, A.P. and Ruilope, L.M.
Journal of Hypertension 30 (4): 647-654. April 2012

Rosuvastatin protects against angiotensin II-induced renal injury in a dose-dependent fashion.
Park, J.K., Mervaala, E.M., Mueller, D.N., Menne, J., Fiebeler, A., Luft, F.C. and Haller, H.
Journal of Hypertension 27 (3): 599-605. March 2009

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor.
Batenburg, W.W., Krop, M., Garrelds, I.M., de Vries, R., de Bruin, R.J.A., Burckle, C.A., Mueller, D.N., Bader, M., Nguyen, G. and Danser, A.H.J.
Journal of Hypertension 25 (12): 2441-2453. December 2007

Magnesium supplementation prevents angiotensin II-induced myocardial damage and CTGF overexpression.
Finckenberg, P., Merasto, S., Louhelainen, M., Lindgren, L., Vapaatalo, H., Mueller, D.N., Luft, F.C. and Mervaala, E.M.
Journal of Hypertension 23 : 375-380. 1 January 2005

Cardiac hypertrophy and fibrosis in chronic L-NAME-treated AT2 receptor-deficient mice.
Gross, V., Obst, M., Kiss, E., Janke, J., Mazak, I., Shagdarsuren, E., Mueller, D.N., Langenickel, T.H., Groene, H.J. and Luft, F.C.
Journal of Hypertension 22 (5): 997-1005. May 2004

Entacapone protects from angiotensin II-induced inflammation and renal injury.
Helkamaa, T., Finckenberg, P., Louhelainen, M., Merasto, S., Rauhala, P., Lapatto, R., Cheng, Z.J., Reenilae, I., Maennistoe, P., Mueller, D.N., Luft, F.C. and Mervaala, E.M.
Journal of Hypertension 21 : 2353-2363. 1 January 2003

A gene expression analysis in rat kidney following high and low salt intake.
Barta, P., Monti, J., Maass, P.G., Gorzelniak, K., Müller, D.N., Dechend, R., Luft, F.C., Hübner, N. and Sharma, A.M.
Journal of Hypertension 20 : 1115-1120. 1 January 2002

Journal of Hypertension : Open Access

CD4(+) T cells play a critical role in mediating hypertension in response to placental ischemia.
Novotny, S., Wallace, K., Herse, F., Moseley, J., Darby, M., Heath, J., Gill, J., Wallukat, G., Martin, J.N., Dechend, R. and LaMarca, B.
Journal of Hypertension : Open Access 2 : 116. 17 June 2013

Journal of Investigative Dermatology

Skin sodium accumulates in psoriasis and reflects disease severity.
Maifeld, A., Wild, J., Karlsen, T.V., Rakova, N., Wistorf, E., Linz, P., Jung, R., Birukov, A., Gimenez-Rivera, V.A., Wilck, N., Bartolomaeus, T., Dechend, R., Kleinewietfeld, M., Forslund, S.K., Krause, A., Kokolakis, G., Philipp, S., Clausen, B.E., Brand, A., Waisman, A., Kurschus, F.C., Wegner, J., Schultheis, M., Luft, F.C., Boschmann, M., Kelm, M., Wiig, H., Kuehne, T., Müller, D.N., Karbach, S. and Markó, L.
Journal of Investigative Dermatology 142 (1): 166-178. January 2022

Journal of Lipid Research

Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway.
Fischer, R., Konkel, A., Mehling, H., Blossey, K., Gapelyuk, A., Wessel, N., von Schacky, C., Dechend, R., Muller, D.N., Rothe, M., Luft, F.C., Weylandt, K. and Schunck, W.H.
Journal of Lipid Research 55 (6): 1150-1164. June 2014

Journal of Maternal-Fetal & Neonatal Medicine

Prediction of birth weight small for gestational age with and without preeclampsia by angiogenic markers: an Odense Child Cohort Study.
Bækgaard Thorsen, L.H., Bjørkholt Andersen, L., Birukov, A., Lykkedegn, S., Dechend, R., Stener Jørgensen, J. and Thybo Christesen, H.
Journal of Maternal-Fetal & Neonatal Medicine 33 (8): 1377-1384. April 2020

Journal of Medicinal Chemistry

17(R),18(S)-epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: structure-activity relationships and stable analogues.
Falck, J.R., Wallukat, G., Puli, N., Goli, M., Arnold, C., Konkel, A., Rothe, M., Fischer, R., Mueller, D.N. and Schunck, W.H.
Journal of Medicinal Chemistry 54 (12): 4109-4118. 23 June 2011

Journal of Molecular Medicine

Spinophilin regulates central angiotensin II-mediated effect on blood pressure.
da Costa Goncalves, A.C., Fontes, M.A., Klussmann, E., Qadri, F., Janke, J., Gollasch, M., Schleifenbaum, J., Mueller, D., Jordan, J., Tank, J., Luft, F.C. and Gross, V.
Journal of Molecular Medicine 89 (12): 1219-1229. December 2011

AT1-receptor autoantibodies and uteroplacental RAS in pregnancy and pre-eclampsia.
Herse, F., Staff, A.C., Hering, L., Mueller, D.N., Luft, F.C. and Dechend, R.
Journal of Molecular Medicine 86 (6): 697-703. June 2008

Aliskiren-mode of action and preclinical data.
Mueller, D.N., Derer, W. and Dechend, R.
Journal of Molecular Medicine 86 (6): 659-662. June 2008

Dysfunction of dysferlin-deficient hearts.
Wenzel, K., Geier, C., Qadri, F., Huebner, N., Schulz, H., Erdmann, B., Gross, V., Bauer, D., Dechend, R., Dietz, R., Osterziel, K.J., Spuler, S. and Oezcelik, C.
Journal of Molecular Medicine 85 (11): 1203-1214. November 2007

Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research.
Bader, M., Peters, J., Baltatu, O., Mueller, D.N., Luft, F.C. and Ganten, D.
Journal of Molecular Medicine 79 (2): 76-102. 1 January 2001

Journal of Neuroimmune Pharmacology

Angiotensin IV is induced in experimental autoimmune encephalomyelitis but fails to influence the disease.
Manzel, A., Domenig, O., Ambrosius, B., Kovacs, A., Stegbauer, J., Poglitsch, M., Mueller, D.N., Gold, R. and Linker, R.A.
Journal of Neuroimmune Pharmacology 9 (4): 533-543. September 2014

Journal of Neuroimmunology

Sodium chloride triggers Th17 mediated autoimmunity.
Haase, S., Wilck, N., Kleinewietfeld, M., Müller, D.N. and Linker, R.A.
Journal of Neuroimmunology 329 : 9-13. 15 April 2019

Journal of Neuroinflammation

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation.
Hammer, A., Schliep, A., Jörg, S., Haghikia, A., Gold, R., Kleinewietfeld, M., Müller, D.N. and Linker, R.A.
Journal of Neuroinflammation 14 (1): 184. 12 September 2017

Journal of Nutrition and Metabolism

Milk products containing bioactive tripeptides have an antihypertensive effect in double transgenic rats (dTGR) harbouring human renin and human angiotensinogen genes.
Jauhiainen, T., Pilvi, T., Cheng, Z.J., Kautiainen, H., Mueller, D.N., Vapaatalo, H., Korpela, R. and Mervaala, E.
Journal of Nutrition and Metabolism 2010 : 287030. 2010

Journal of Parenteral and Enteral Nutrition

Impact of intravenous fish oil on omega-3 fatty acids and their derived lipid metabolites in patients with parenteral nutrition.
Weylandt, K.H., Karber, M., Xiao, Y., Zhang, I.W., Pevny, S., Blüthner, E., von Schacky, C., Rothe, M., Schunck, W.H. and Pape, U.F.
Journal of Parenteral and Enteral Nutrition 47 (2): 287-300. 26 September 2022

Journal of Reproductive Immunology

Can single-cell and spatial omics unravel the pathophysiology of pre-eclampsia?
Hartmann, S., Botha, S.M., Gray, C.M., Valdes, D.S., Tong, S., Kaitu’u-Lino, T.J., Herse, F., Bergman, L., Cluver, C.A., Dechend, R. and Nonn, O.
Journal of Reproductive Immunology 159 : 104136. September 2023

Circulating angiotensin II type I receptor – autoantibodies in diabetic pregnancies.
Linge, L.L., Sugulle, M., Wallukat, G., Dechend, R. and Staff, A.C.
Journal of Reproductive Immunology 155 : 103777. February 2023

Circulating HLA-G and its association with cardiovascular markers in pregnancy.
Lekva, T., Jacobsen, D.P., Sugulle, M., Moe, K., Fjeldstad, H.E.S., Dechend, R. and Staff, A.C.
Journal of Reproductive Immunology 146 : 103331. August 2021

Lymphocyte characterization of decidua basalis spiral arteries with acute atherosis in preeclamptic and normotensive pregnancies.
Johnsen, G.M., Størvold, G.L., Alnaes-Katjavivi, P.H., Roald, B., Golic, M., Dechend, R., Redman, C.W.G. and Staff, A.C.
Journal of Reproductive Immunology 132 : 42-48. April 2019

Auto-antibodies against the angiotensin II type I receptor in women with uteroplacental acute atherosis and preeclampsia at delivery and several years postpartum.
Rieber-Mohn, A.B., Sugulle, M., Wallukat, G., Alnæs-Katjavivi, P., Leite Størvold, G., Bolstad, N., Redman, C.W., Dechend, R. and Staff, A.C.
Journal of Reproductive Immunology 128 : 23-29. August 2018

The association between angiogenic markers and fetal sex: implications for preeclampsia research.
Andersen, L.B., Jørgensen, J.S., Herse, F., Andersen, M.S., Christesen, H.T. and Dechend, R.
Journal of Reproductive Immunology 117 : 24-29. September 2016

Novel ideas about salt, blood pressure, and pregnancy.
Rakova, N., Muller, D.N., Staff, A.C., Luft, F.C. and Dechend, R.
Journal of Reproductive Immunology 101-102 : 135-139. March 2014

Preeclampsia and uteroplacental acute atherosis: immune and inflammatory factors.
Staff, A.C., Johnsen, G.M., Dechend, R. and Redman, C.W.G.
Journal of Reproductive Immunology 101-102 : 120-126. February 2014

Journal of Vascular Research

Protective function of Ahnak1 in vascular healing after wire injury.
Haase, N., Rüder, C., Haase, H., Kamann, S., Kouno, M., Morano, I., Dechend, R., Zohlnhöfer, D. and Haase, T.
Journal of Vascular Research 54 (3): 131-142. May 2017

Journal of the American College of Cardiology

Subacute coronary stent thrombosis in cancer patients.
Gross, C.M., Posch, M.G., Geier, C., Olthoff, H., Kraemer, J., Dechend, R., Dietz, R. and Oezcelik, C.
Journal of the American College of Cardiology 51 (12): 1232-1233. 25 March 2008

Journal of the American Heart Association

Vitamin D depletion aggravates hypertension and target-organ damage.
Andersen, L.B., Przybyl, L., Haase, N., von Versen-Höynck, F., Qadri, F., Jørgensen, J.S., Sorensen, G.L., Fruekilde, P., Poglitsch, M., Szijártó, I., Gollasch, M., Peters, J., Muller, D.N., Christesen, H.T. and Dechend, R.
Journal of the American Heart Association 4 (2): e001417. February 2015

Journal of the American Society of Hypertension

Soluble (pro)renin receptor in preeclampsia and diabetic pregnancies.
Sugulle, M., Heidecke, H., Maschke, U., Herse, F., Danser, A.H.J., Mueller, D.N., Staff, A.C. and Dechend, R.
Journal of the American Society of Hypertension 11 (10): 644-652. October 2017

Vitamin D depletion does not affect key aspects of the preeclamptic phenotype in a transgenic rodent model for preeclampsia.
Andersen, L.B., Golic, M., Przybyl, L., Sorensen, G.L., Jørgensen, J.S., Fruekilde, P., von Versen-Höynck, F., Herse, F., Højskov, C.S., Dechend, R., Christesen, H.T. and Haase, N.
Journal of the American Society of Hypertension 10 (7): 597-607.e1. July 2016

Diagnosis of preeclampsia with soluble Fms-like tyrosine kinase 1/placental growth factor ratio: an inter-assay comparison.
Andersen, L.B., Frederiksen-Møller, B., Work Havelund, K., Dechend, R., Jørgensen, J.S., Jensen, B.L., Nielsen, J., Lykkedegn, S., Barington, T. and Christesen, H.T.
Journal of the American Society of Hypertension 9 (2): 86-96. February 2015

Gunfight at O.K. CORAL.
Luft, F.C., Safak, E. and Dechend, R.
Journal of the American Society of Hypertension 8 (4): 276-280. April 2014

Long-term follow-up of patients with atherosclerotic renal artery disease.
Safak, E., Wilke, C., Derer, W., Busjahn, A., Gross, M., Moeckel, M., Mueller, D.N., Luft, F.C. and Dechend, R.
Journal of the American Society of Hypertension 7 (1): 24-31. January 2013

Agonistic antibodies directed at cell surface receptors and cardiovascular disease.
Luft, F.C., Dechend, R., Dragun, D., Mueller, D.N. and Wallukat, G.
Journal of the American Society of Hypertension 2 (1): 8-14. January 2008

Journal of the American Society of Nephrology

Inflammation in children with chronic kidney disease linked to gut dysbiosis and metabolite imbalance.
Holle, J., Bartolomaeus, H., Löber, U., Behrens, F., Bartolomaeus, T.U.P., Anandakumar, H., Wimmer, M., Vu, D.L., Kuhring, M., Brüning, U., Maifeld, A., Geisberger, S., Kempa, S., Schumacher, F., Kleuser, B., Bufler, P., Querfeld, U., Kitschke, S., Engler, D., Kuhrt, L.D., Drechsel, O., Eckardt, K.U., Forslund, S., Thürmer, A., McParland, V., Kirwan, J., Wilck, N. and Mueller, D.
Journal of the American Society of Nephrology 33 (12): 2259-2275. December 2022

Tubular epithelial NF-κB activity regulates ischemic AKI.
Markó, L., Vigolo, E., Hinze, C., Park, J.K., Roël, G., Balogh, A., Choi, M., Wübken, A., Cording, J., Blasig, I.E., Luft, F.C., Scheidereit, C., Schmidt-Ott, K.M., Schmidt-Ullrich, R. and Müller, D.N.
Journal of the American Society of Nephrology 27 (9): 2658-2669. September 2016

Prorenin receptor is essential for podocyte autophagy and survival.
Riediger, F., Quack, I., Qadri, F., Hartleben, B., Park, J.K., Potthoff, S.A., Sohn, D., Sihn, G., Rousselle, A., Fokuhl, V., Maschke, U., Purfürst, B., Schneider, W., Rump, L.C., Luft, F.C., Dechend, R., Bader, M., Huber, T.B., Nguyen, G. and Mueller, D.N.
Journal of the American Society of Nephrology 22 (12): 2193-2202. December 2011

The biology of the (pro)renin receptor.
Nguyen, G. and Mueller, D.N.
Journal of the American Society of Nephrology 21 (1): 18-23. January 2010

The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling.
Feldt, S., Maschke, U., Dechend, R., Luft, F.C. and Mueller, D.N.
Journal of the American Society of Nephrology 19 (4): 743-748. April 2008

Postischemic acute renal failure is reduced by short-term statin treatment in a rat model.
Gueler, F., Rong, S., Park, J.K., Fiebeler, A., Menne, J., Elger, M., Mueller, D.N., Hampich, F., Dechend, R., Kunter, U., Luft, F.C. and Haller, H.
Journal of the American Society of Nephrology 13 (9): 2288-2298. 1 September 2002

Journal of the Renin Angiotensin Aldosterone System

Vitamin D review.
Mueller, D.N., Kleinewietfeld, M. and Kvakan, H.
Journal of the Renin Angiotensin Aldosterone System 12 (2): 125-128. June 2011

Spotlight on renin. Mechanisms of hypertension-induced target organ damage.
Mueller, D.N.
Journal of the Renin Angiotensin Aldosterone System 8 (3): 148-150. September 2007

Low-dose renin inhibitor and low-dose AT(1)-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes.
Dechend, R., Shagdarsuren, E., Gratze, P., Fiebeler, A., Pilz, B., Meiners, S., Derer, W., Feldman, D.L., Webb, R. and Mueller, D.N.
Journal of the Renin Angiotensin Aldosterone System 8 (2): 81-84. June 2007

Journal of the Society for Gynecologic Investigation

Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia.
Dechend, R., Homuth, V., Wallukat, G., Mueller, D.N., Krause, M., Dudenhausen, J., Haller, H. and Luft, F.C.
Journal of the Society for Gynecologic Investigation 13 : 79-86. February 2006

Kardiologe

Besondere Bluthochdruckfälle: Leitlinienempfehlungen der European Society of Cardiology und European Society of Hypertension [Special cases of high blood pressure: Guideline recommendations of the European Society of Cardiology and European Society of Hypertension].
Derer, W. and Dechend, R.
Kardiologe 8 (5): 419-428. October 2014

24-h-Langzeitblutdruckmessung (ABDM): Statement der Deutschen Hochdruckliga e. V. DHL (Deutsche Gesellschaft für Hypertonie und Praevention), Sektion Hochdruckdiagnostik [Ambulatory blood pressure monitoring (ABPM): Statement of the German Hypertension League DHL (German Society of Hypertension and Prevention), working group for hypertension diagnostics].
Lüders, S., Dechend, R., Eckert, S., Mengden, T., Nürnberger, J., Tholl, U. and Sanner, B.
Kardiologe 7 (3): 194-208. June 2013

Kardiologie

Influenzaimpfung – Mehr als nur Influenzaschutz [Influenza vaccination – more than just protection against the flu].
Dechend, R.
Kardiologie 17 (6): 434-440. December 2023

Lösliche Guanylatzyklase(sGC)-Stimulation mit Vericiguat: Von der pharmakologischen Idee bis zur Therapie der chronischen Herzinsuffizienz [Soluble guanylate cyclase (sGC) stimulation with vericiguat : from the pharmacological idea to the treatment of chronic heart failure].
Haase, N., Kedziora, S.M., Mueller, D.N. and Dechend, R.
Kardiologie 16 (6): 466-478. December 2022

Kidney International

Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury.
Vigolo, E., Markó, L., Hinze, C., Müller, D.N., Schmidt-Ullrich, R. and Schmidt-Ott, K.M.
Kidney International 95 (1): 108-122. January 2019

Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients.
Dahlmann, A., Dörfelt, K., Eicher, F., Linz, P., Kopp, C., Mössinger, I., Horn, S., Büschges-Seraphin, B., Wabel, P., Hammon, M., Cavallaro, A., Eckardt, K.U., Kotanko, P., Levin, N.W., Johannes, B., Uder, M., Luft, F.C., Müller, D.N. and Titze, J.M.
Kidney International 87 (2): 434-441. February 2015

Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury.
Hoff, U., Lukitsch, I., Chaykovska, L., Ladwig, M., Arnold, C., Manthati, V.L., Fuller, T.F., Schneider, W., Gollasch, M., Mueller, D.N., Flemming, B., Seeliger, E., Luft, F.C., Falck, J.R., Dragun, D. and Schunck, W.H.
Kidney International 79 (1): 57-65. January 2011

Effect of (pro)renin receptor inhibition by a decoy peptide on renal damage in the clipped kidney of Goldblatt rats.
Krebs, C., Weber, M., Steinmetz, O., Meyer-Schwesinger, C., Stahl, R., Danser, A.H., Garrelds, I., van Goor, H., Nguyen, G., Mueller, D.N. and Wenzel, U.
Kidney International 74 (6): 823-824. 2 September 2008

Inducible NOS inhibition, eicosapentaenoic acid supplementation, and angiotensin II-induced renal damage.
Theuer, J., Shagdarsuren, E., Muller, D.N., Kaergel, E., Honeck, H., Park, J.K., Fiebeler, A., Dechend, R., Haller, H., Luft, F.C. and Schunck, W.H.
Kidney International 67 : 248-258. 1 January 2005

Nitric oxide synthase expression in AT receptor-deficient mice after DOCA-salt.
Obst, M., Gross, V., Bonartsev, A., Janke, J., Mueller, D.N., Park, J.K., Kaergel, E. and Luft, F.C.
Kidney International 65 (6): 2268-2278. June 2004

Lipoic acid supplementation prevents angiotensin II-induced renal injury.
Mervaala, E., Finckenberg, P., Lapatto, R., Mueller, D.N., Park, J.K., Dechend, R., Ganten, D., Vapaatalo, H. and Luft, F.C.
Kidney International 64 (2): 501-508. August 2003

Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects.
Park, J.K., Mueller, D.N., Mervaala, E.M.A., Dechend, R., Fiebeler, A., Schmidt, F., Bieringer, M., Schaefer, O., Lindschau, C., Schneider, W., Ganten, D., Luft, F.C. and Haller, H.
Kidney International 58 (4): 1420-1430. 1 October 2000

Kidney International Reports

Reduction of tissue Na(+) accumulation after renal transplantation.
Dahlmann, A., Linz, P., Zucker, I., Haag, V., Jantsch, J., Dienemann, T., Nagel, A.M., Neubert, P., Rosenhauer, D., Rauh, M., Horn, S., Müller, D.N., Schiffer, M., Luft, F.C., Uder, M. and Kopp, C.
Kidney International Reports 6 (9): 2338-2347. September 2021

Klinikarzt

Behandlung der arteriellen Hypertonie - Aspekte der neuen europäischen Leitlinien [Treatment of arterial hypertension - Issues of the new european guidelines].
Derer, W., Dechend, R. and Baberg, H.
Klinikarzt 43 (3): 130-135. March 2014

Laboratory Animals

Influence of estrogen on individual exercise motivation and bone protection in ovariectomized rats.
Müller, S.T., Keiler, A.M., Kräker, K., Zierau, O. and Bernhardt, R.
Laboratory Animals 52 (5): 479-489. October 2018

Lancet

Endothelin antagonists and the quest for a new therapeutic option in resistant hypertension.
Dechend, R. and Delles, C.
Lancet 400 (10367): 1900-1901. 3 December 2022

Lancet Global Health

A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test.
Scioscia, M., Dekker, G.A., Chaouat, G., Dawonauth, L., Dechend, R., Goldman-Wohl, D., Gumilar, E., Karumanchi, S.A., Kell, D.B., Rademacher, T.W., Robertson, S., Saito, S., Scherjon, S., Staff, A.C., Vatish, M. and Robillard, P.Y.
Lancet Global Health 7 (10): e1312-e1313. October 2019

MMW Fortschritte der Medizin

Diagnostik, Therapie und die Bedeutung der Lebensqualität von Patienten mit chronischem Koronarsyndrom [Diagnostics, therapy and the importance of quality of life in patients with chronic coronary syndrome. Results oft the general practitioner care study ALTHEA].
Dechend, R.
MMW Fortschritte der Medizin 164 (Suppl 6): 11-17. 22 April 2022

Neue Antihypertensiva in Sicht [New antihypertensive drugs].
Derer, W., Mueller, D.N. and Dechend, R.
In: UNSPECIFIED. 8 March 2012

MMW: Fortschritte der Medizin

Stellenwert der fixen Dreierkombination [The role of triple-drug, fixed-dose combinations for the treatment of hypertension].
Derer, W., Mueller, D.N. and Dechend, R.
In: UNSPECIFIED. 17 November 2011

Aldosteronantagonisten: Welchen Stellenwert haben sie in der antihypertensien Therapie? [Mineralocorticoid receptor antagonists: inhibition of the renin angiotensin system].
Derer, W., Dechend, R. and Mueller, D.N.
MMW: Fortschritte der Medizin 152 (6): 48-49. 11 February 2010

Antihypertensive Behandlung. Bei Risikopatienten von Anfang an fix kombinieren [Fixed-dose combinations in antihypertensive treatment: is it necessary to examine the effectiveness of each component?].
Dechend, R., Derer, W. and Mueller, D.N.
MMW: Fortschritte der Medizin 151 (45): 46-47. 5 November 2009

Microbial Ecology

Microbiome dynamics and functional composition in Coelopa frigida (Diptera, Coelopidae): insights into trophic specialization of kelp flies.
Bischof, P.S.P., Bartolomaeus, T.U.P., Löber, U. and Bleidorn, C.
Microbial Ecology 87 (1): 91. 3 July 2024

Molecular Neurodegeneration

Increase of angiotensin II type 1 receptor auto-antibodies in Huntington's disease.
Lee, D.H., Heidecke, H., Schröder, A., Paul, F., Wachter, R., Hoffmann, R., Ellrichmann, G., Dragun, D., Waschbisch, A., Stegbauer, J., Klotz, P., Gold, R., Dechend, R., Müller, D.N., Saft, C. and Linker, R.A.
Molecular Neurodegeneration 9 (1): 49. 15 November 2014

NMR in Biomedicine

Skin sodium measured with (23)Na MRI at 7.0 T.
Linz, P., Santoro, D., Renz, W., Rieger, J., Ruehle, A., Ruff, J., Deimling, M., Rakova, N., Muller, D.N., Luft, F.C., Titze, J. and Niendorf, T.
NMR in Biomedicine 28 (1): 54-62. January 2015

Nature

Salt-responsive gut commensal modulates T(H)17 axis and disease.
Wilck, N., Matus, M.G., Kearney, S.M., Olesen, S.W., Forslund, K., Bartolomaeus, H., Haase, S., Mähler, A., Balogh, A., Markó, L., Vvedenskaya, O., Kleiner, F.H., Tsvetkov, D., Klug, L., Costea, P.I., Sunagawa, S., Maier, L., Rakova, N., Schatz, V., Neubert, P., Frätzer, C., Krannich, A., Gollasch, M., Grohme, D.A., Côrte-Real, B.F., Gerlach, R.G., Basic, M., Typas, A., Wu, C., Titze, J.M., Jantsch, J., Boschmann, M., Dechend, R., Kleinewietfeld, M., Kempa, S., Bork, P., Linker, R.A., Alm, E.J. and Müller, D.N.
Nature 551 (7682): 585-589. 30 November 2017

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Kleinewietfeld, M., Manzel, A., Titze, J., Kvakan, H., Yosef, N., Linker, R.A., Muller, D.N. and Hafler, D.A.
Nature 496 (7446): 518-522. 25 April 2013

Nature Communications

Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity.
Cabral-Marques, O., Halpert, G., Schimke, L.F., Ostrinski, Y., Vojdani, A., Baiocchi, G.C., Freire, P.P., Filgueiras, I.S., Zyskind, I., Lattin, M.T., Tran, F., Schreiber, S., Marques, A.H.C., Plaça, D.R., Fonseca, D.L.M., Humrich, J.Y., Müller, A., Giil, L.M., Graßhoff, H., Schumann, A., Hackel, A., Junker, J., Meyer, C., Ochs, H.D., Lavi, Y.B., Scheibenbogen, C., Dechend, R., Jurisica, I., Schulze-Forster, K., Silverberg, J.I., Amital, H., Zimmerman, J., Heidecke, H., Rosenberg, A.Z., Riemekasten, G. and Shoenfeld, Y.
Nature Communications 13 (1): 1220. 9 March 2022

Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients.
Maifeld, A., Bartolomaeus, H., Löber, U., Avery, E.G., Steckhan, N., Markó, L., Wilck, N., Hamad, I., Šušnjar, U., Mähler, A., Hohmann, C., Chen, C.Y., Cramer, H., Dobos, G., Lesker, T.R., Strowig, T., Dechend, R., Bzdok, D., Kleinewietfeld, M., Michalsen, A., Müller, D.N. and Forslund, S.K.
Nature Communications 12 (1): 1970. 30 March 2021

Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Schewe, J., Seidel, E., Forslund, S., Marko, L., Peters, J., Muller, D.N., Fahlke, C., Stölting, G. and Scholl, U.
Nature Communications 10 (1): 5155. 14 November 2019

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis.
Cabral-Marques, O., Marques, A., Giil, L.M., De Vito, R., Rademacher, J., Günther, J., Lange, T., Humrich, J.Y., Klapa, S., Schinke, S., Schimke, L.F., Marschner, G., Pitann, S., Adler, S., Dechend, R., Müller, D.N., Braicu, I., Sehouli, J., Schulze-Forster, K., Trippel, T., Scheibenbogen, C., Staff, A., Mertens, P.R., Löbel, M., Mastroianni, J., Plattfaut, C., Gieseler, F., Dragun, D., Engelhardt, B.E., Fernandez-Cabezudo, M.J., Ochs, H.D., Al-Ramadi, B.K., Lamprecht, P., Mueller, A., Heidecke, H. and Riemekasten, G.
Nature Communications 9 (1): 5224. 6 December 2018

Nature Medicine

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Machnik, A., Neuhofer, W., Jantsch, J., Dahlmann, A., Tammela, T., Machura, K., Park, J.K., Beck, F.X., Mueller, D.N., Derer, W., Goss, J., Ziomber, A., Dietsch, P., Wagner, H., van Rooijen, N., Kurtz, A., Hilgers, K.F., Alitalo, K., Eckardt, K.U., Luft, F.C., Kerjaschki, D. and Titze, J.
Nature Medicine 15 (5): 545-552. May 2009

Nature Neuroscience

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Kierdorf, K., Erny, D., Goldmann, T., Sander, V., Schulz, C., Perdiguero, E.G., Wieghofer, P., Heinrich, A., Riemke, P., Hoelscher, C., Müller, D.N., Luckow, B., Brocker, T., Debowski, K., Fritz, G., Opdenakker, G., Diefenbach, A., Biber, K., Heikenwalder, M., Geissmann, F., Rosenbauer, F. and Prinz, M.
Nature Neuroscience 16 (3): 273-280. March 2013

Nature Reviews Immunology

Salt sensitivity includes effects on immune cell signalling and metabolism.
Müller, D.N., Geisberger, S., Kleinewietfeld, M. and Jantsch, J.
Nature Reviews Immunology 23 (6): 341-342. June 2023

Sodium in the microenvironment regulates immune responses and tissue homeostasis.
Müller, D.N., Wilck, N., Haase, S., Kleinewietfeld, M. and Linker, R.A.
Nature Reviews Immunology 19 (4): 243-254. April 2019

Nature Reviews Nephrology

The (pro)renin receptor: what's in a name?
Simons, M., Bader, M. and Müller, D.N.
Nature Reviews Nephrology 16 (5): 304. May 2020

The role of sodium in modulating immune cell function.
Wilck, N., Balogh, A., Markó, L., Bartolomaeus, H. and Müller, D.N.
Nature Reviews Nephrology 15 (9): 546-558. September 2019

Nephrologe

Nicht-Vitamin-K-abhängige orale Antikoagulanzien (NOAK) bei chronischer Niereninsuffizienz [Non-vitamin K antagonist oral anticoagulants (NOAC) in chronic kidney disease].
Schlieper, G., Remppis, A., Schwenger, V., Keller, T., Dechend, R., Massberg, S., Baldus, S., Weinreich, T., Hetzel, G., Floege, J., Hoyer, J., Mahfoud, F. and Fliser, D.
Nephrologe 13 (2): 91-98. March 2018

Neue Entwicklungen auf dem Gebiet der Präeklampsie [New developments in the field of preeclampsia].
Golic, M. and Dechend, R.
Nephrologe 12 (2): 115-120. March 2017

Nephrology Dialysis Transplantation

Battle against the renin-angiotensin system: help from an unexpected party.
Mueller, D. and Mueller, D.N.
Nephrology Dialysis Transplantation 24 (4): 1110-1112. April 2009

Statins and angiotensin II-induced vascular injury.
Dechend, R., Müller, D., Park, J.K., Fiebeler, A., Haller, H. and Luft, F.C.
Nephrology Dialysis Transplantation 17 : 349-353. 1 January 2002

New England Journal of Medicine

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection (authors reply inN Engl J Med. 2005 May 12;352(19):2027-8).
Dragun, D., Mueller, D.N., Braesen, J.H., Fritsche, L., Nieminen-Kelhae, M., Dechend, R., Kintscher, U., Rudolph, B., Hoebeke, J., Eckert, D., Mazak, I., Plehm, R., Schoenemann, C., Unger, T., Budde, K., Neumayer, H.H., Luft, F.C. and Wallukat, G.
New England Journal of Medicine 352 (6): 558-569. 1 January 2005

Nieren- und Hochdruckkrankheiten

Dieter Klaus und die Bluthochdruckforschung.
Gollasch, M., Tsvetkov, D. and Müller, D.
Nieren- und Hochdruckkrankheiten 47 (1): 40-46. January 2018

Die direkte Renin-Inhibition - ein neuer Ansatz in der therapeutischen Blockade des Renin-Angiotensin-Systems [Direct renin inhibition - a new approach in the therapeutic blockade of the renin-angiotensin system].
Derer, W. and Mueller, D.N.
Nieren- und Hochdruckkrankheiten 36 (11): 549-550. November 2007

Nutrients

Impact of high salt-intake on a natural gut ecosystem in wildling mice.
Cardilli, A., Hamad, I., Dyczko, A., Thijs, S., Vangronsveld, J., Müller, D.N., Rosshart, S.P. and Kleinewietfeld, M.
Nutrients 15 (7): 1565. 23 March 2023

Increased salt intake decreases diet-induced thermogenesis in healthy volunteers: a randomized placebo-controlled study.
Mähler, A., Klamer, S., Maifeld, A., Bartolomaeus, H., Markó, L., Chen, C.Y., Forslund, S.K., Boschmann, M., Müller, D.N. and Wilck, N.
Nutrients 14 (2): 253. 7 January 2022

Optics InfoBase Conference Papers

Microscopy with undetected photons in the mid-infrared.
Kviatkovsky, I., Chrzanowski, H.M., Avery, E.G., Bartolomaeus, H. and Ramelow, S.
In: Conference on Lasers and Electro-Optics 2021, 9-14 May 2021, San Jose, CA, USA. May 2021

PLoS Biology

NCX1 represents an ionic Na(+) sensing mechanism in macrophages.
Neubert, P., Homann, A., Wendelborn, D., Bär, A.L., Krampert, L., Trum, M., Schröder, A., Ebner, S., Weichselbaum, A., Schatz, V., Linz, P., Veelken, R., Schulte-Schrepping, J., Aschenbrenner, A.C., Quast, T., Kurts, C., Geisberger, S., Kunzelmann, K., Hammer, K., Binger, K.J., Titze, J., Müller, D.N., Kolanus, W., Schultze, J.L., Wagner, S. and Jantsch, J.
PLoS Biology 18 (6): e3000722. 22 June 2020

PLoS Computational Biology

Ten simple rules for implementing open and reproducible research practices after attending a training course.
Heise, V., Holman, C., Lo, H., Lyras, E.M., Adkins, M.C., Aquino, M.R.J., Bougioukas, K.I., Bray, K.O., Gajos, M., Guo, X., Hartling, C., Huerta-Gutierrez, R., Jindrová, M., Kenney, J.P.M., Kępińska, A.P., Kneller, L., Lopez-Rodriguez, E., Mühlensiepen, F., Richards, A., Richards, G., Siebert, M., Smith, J.A., Smith, N., Stransky, N., Tarvainen, S., Valdes, D.S., Warrington, K.L., Wilpert, N.M., Witkowska, D., Zaneva, M., Zanker, J. and Weissgerber, T.L.
PLoS Computational Biology 19 (1): e1010750. 5 January 2023