Browse by Research Team

2022

Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve.
Kleineidam, L., Wolfsgruber, S., Weyrauch, A.S., Zulka, L.E., Forstmeier, S., Roeske, S., van den Bussche, H., Kaduszkiewicz, H., Wiese, B., Weyerer, S., Werle, J., Fuchs, A., Pentzek, M., Brettschneider, C., König, H.H., Weeg, D., Bickel, H., Luppa, M., Rodriguez, F.S., Freiesleben, S.D., Erdogan, S., Unterfeld, C., Peters, O., Spruth, E.J., Altenstein, S., Lohse, A., Priller, J., Fliessbach, K., Kobeleva, X., Schneider, A., Bartels, C., Schott, B.H., Wiltfang, J., Maier, F., Glanz, W., Incesoy, E.I., Butryn, M., Düzel, E., Buerger, K., Janowitz, D., Ewers, M., Rauchmann, B.S., Perneczky, R., Kilimann, I., Görß, D., Teipel, S., Laske, C., Munk, M.H.J., Spottke, A., Roy, N., Brosseron, F., Heneka, M.T., Ramirez, A., Yakupov, R., Scherer, M., Maier, W., Jessen, F., Riedel-Heller, S.G. and Wagner, M.
Frontiers in Psychology 13 : 957308. 8 December 2022

2021

Overcoming barriers to the adoption of locating technologies in dementia care: a multi-stakeholder focus group study.
Freiesleben, S.D., Megges, H., Herrmann, C., Wessel, L. and Peters, O.
BMC Geriatrics 21 (1): 378. 21 June 2021

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas, I., Moreno-Grau, S., Tesi, N., Grenier-Boley, B., Andrade, V., Jansen, I.E., Pedersen, N.L., Stringa, N., Zettergren, A., Hernández, I., Montrreal, L., Antúnez, C., Antonell, A., Tankard, R.M., Bis, J.C., Sims, R., Bellenguez, C., Quintela, I., González-Perez, A., Calero, M., Franco-Macías, E., Macías, J., Blesa, R., Cervera-Carles, L., Menéndez-González, M., Frank-García, A., Royo, J.L., Moreno, F., Huerto Vilas, R., Baquero, M., Diez-Fairen, M., Lage, C., García-Madrona, S., García-González, P., Alarcón-Martín, E., Valero, S., Sotolongo-Grau, O., Ullgren, A., Naj, A.C., Lemstra, A.W., Benaque, A., Pérez-Cordón, A., Benussi, A., Rábano, A., Padovani, A., Squassina, A., de Mendonça, A., Arias Pastor, A., Kok, A.A.L., Meggy, A., Pastor, A.B., Espinosa, A., Corma-Gómez, A., Martín Montes, A., Sanabria, Á., DeStefano, A.L., Schneider, A., Haapasalo, A., Kinhult Ståhlbom, A., Tybjærg-Hansen, A., Hartmann, A.M., Spottke, A., Corbatón-Anchuelo, A., Rongve, A., Borroni, B., Arosio, B., Nacmias, B., Nordestgaard, B.G., Kunkle, B.W., Charbonnier, C., Abdelnour, C., Masullo, C., Martínez Rodríguez, C., Muñoz-Fernandez, C., Dufouil, C., Graff, C., Ferreira, C.B., Chillotti, C., Reynolds, C.A., Fenoglio, C., Van Broeckhoven, C., Clark, C., Pisanu, C., Satizabal, C.L., Holmes, C., Buiza-Rueda, D., Aarsland, D., Rujescu, D., Alcolea, D., Galimberti, D., Wallon, D., Seripa, D., Grünblatt, E., Dardiotis, E., Düzel, E., Scarpini, E., Conti, E., Rubino, E., Gelpi, E., Rodriguez-Rodriguez, E., Duron, E., Boerwinkle, E., Ferri, E., Tagliavini, F., Küçükali, F., Pasquier, F., Sanchez-Garcia, F., Mangialasche, F., Jessen, F., Nicolas, G., Selbæk, G., Ortega, G., Chêne, G., Hadjigeorgiou, G., Rossi, G., Spalletta, G., Giaccone, G., Grande, G., Binetti, G., Papenberg, G., Hampel, H., Bailly, H., Zetterberg, H., Soininen, H., Karlsson, I.K., Alvarez, I., Appollonio, I., Giegling, I., Skoog, I., Saltvedt, I., Rainero, I., Rosas Allende, I., Hort, J., Diehl-Schmid, J., Van Dongen, J., Vidal, J.S., Lehtisalo, J., Wiltfang, J., Thomassen, J.Q., Kornhuber, J., Haines, J.L., Vogelgsang, J., Pineda, J.A., Fortea, J., Popp, J., Deckert, J., Buerger, K., Morgan, K., Fließbach, K., Sleegers, K., Molina-Porcel, L., Kilander, L., Weinhold, L., Farrer, L.A., Wang, L.S., Kleineidam, L., Farotti, L., Parnetti, L., Tremolizzo, L., Hausner, L., Benussi, L., Froelich, L., Ikram, M.A., Deniz-Naranjo, M.C., Tsolaki, M., Rosende-Roca, M., Löwenmark, M., Hulsman, M., Spallazzi, M., Pericak-Vance, M.A., Esiri, M., Bernal Sánchez-Arjona, M., Dalmasso, M.C., Martínez-Larrad, M.T., Arcaro, M., Nöthen, M.M., Fernández-Fuertes, M., Dichgans, M., Ingelsson, M., Herrmann, M.J., Scherer, M., Vyhnalek, M., Kosmidis, M.H., Yannakoulia, M., Schmid, M., Ewers, M., Heneka, M.T., Wagner, M., Scamosci, M., Kivipelto, M., Hiltunen, M., Zulaica, M., Alegret, M., Fornage, M., Roberto, N., van Schoor, N.M., Seidu, N.M., Banaj, N., Armstrong, N.J., Scarmeas, N., Scherbaum, N., Goldhardt, O., Hanon, O., Peters, O., Skrobot, O.A., Quenez, O., Lerch, O., Bossù, P., Caffarra, P., Dionigi Rossi, P., Sakka, P., Mecocci, P., Hoffmann, P., Holmans, P.A., Fischer, P., Riederer, P., Yang, Q., Marshall, R., Kalaria, R.N., Mayeux, R., Vandenberghe, R., Cecchetti, R., Ghidoni, R., Frikke-Schmidt, R., Sorbi, S., Hägg, S., Engelborghs, S., Helisalmi, S., Botne Sando, S., Kern, S., Archetti, S., Boschi, S., Fostinelli, S., Gil, S., Mendoza, S., Mead, S., Ciccone, S., Djurovic, S., Heilmann-Heimbach, S., Riedel-Heller, S., Kuulasmaa, T., Del Ser, T., Lebouvier, T., Polak, T., Ngandu, T., Grimmer, T., Bessi, V., Escott-Price, V., Giedraitis, V., Deramecourt, Vi., Maier, W., Jian, X., Pijnenburg, Y.A.L., Kehoe, P.G., Garcia-Ribas, G., Sánchez-Juan, P., Pastor, P., Pérez-Tur, J., Piñol-Ripoll, G., Lopez de Munain, A., García-Alberca, J.M., Bullido, M.J., Álvarez, V., Lleó, A., Real, L.M., Mir, P., Medina, M., Scheltens, P., Holstege, H., Marquié, M., Sáez, M.E., Carracedo, Á., Amouyel, P., Schellenberg, G.D., Williams, J., Seshadri, S., van Duijn, C.M., Mather, K.A., Sánchez-Valle, R., Serrano-Ríos, M., Orellana, A., Tárraga, L., Blennow, K., Huisman, M., Andreassen, O.A., Posthuma, D., Clarimón, J., Boada, M., van der Flier, W.M., Ramirez, A., Lambert, J.C., van der Lee, S.J. and Ruiz, A.
Nature Communications 12 (1): 3417. 7 June 2021

2020

Value of neuropsychological tests to identify patients with depressive symptoms on the Alzheimer's disease continuum.
Menne, F., Schipke, C.G., Klostermann, A., Fuentes-Casañ, M., Freiesleben, S.D., Bauer, C. and Peters, O.
Journal of Alzheimer's Disease 78 (2): 819-826. 10 November 2020

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Dembny, P., Newman, A.G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., Kleinau, G., Derkow, K., Richard, B.C., Schipke, C., Scheidereit, C., Stachelscheid, H., Golenbock, D., Peters, O., Coleman, M., Heppner, F.L., Scheerer, P., Tarabykin, V., Ruprecht, K., Izsvák, Z., Mayer, J. and Lehnardt, S.
JCI Insight 5 (7): e131093. 9 April 2020

2019

A combined miRNA-piRNA signature to detect Alzheimer's disease.
Jain, G., Stuendl, A., Rao, P., Berulava, T., Pena Centeno, T., Kaurani, L., Burkhardt, S., Delalle, I., Kornhuber, J., Hüll, M., Maier, W., Peters, O., Esselmann, H., Schulte, C., Deuschle, C., Synofzik, M., Wiltfang, J., Mollenhauer, B., Maetzler, W., Schneider, A. and Fischer, A.
Translational Psychiatry 9 (1): 250. 7 October 2019

2018

User experience and clinical effectiveness with two wearable global positioning system devices in home dementia care.
Megges, H., Freiesleben, S.D., Rösch, C., Knoll, N., Wessel, L. and Peters, O.
Alzheimer's and Dementia: Translational Research and Clinical Interventions 4 : 636-644. 9 November 2018

Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease.
Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. and Jankowski, V.
Neurology 91 (19): e1799-e1808. 6 November 2018

2017

Correlation of florbetaben PET imaging and the amyloid peptide Aβ42 in cerebrospinal fluid.
Schipke, C.G., Koglin, N., Bullich, S., Joachim, L.K., Haas, B., Seibyl, J., Barthel, H., Sabri, O. and Peters, O.
Psychiatry Research 265 : 98-101. 30 July 2017

2015

Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naive patients with mild-to-moderate Alzheimer's disease.
Peters, O., Fuentes, M., Joachim, L.K., Jessen, F., Luckhaus, C., Kornhuber, J., Pantel, J., Huell, M., Schmidtke, K., Ruether, E., Moeller, H.J., Kurz, A., Wiltfang, J., Maier, W., Wiese, B., Froelich, L. and Heuser, I.
Alzheimer's and Dementia 1 (3): 198-204. November 2015

Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood.
Memczak, S., Papavasileiou, P., Peters, O. and Rajewsky, N.
PLoS ONE 10 (10): e0141214. 20 October 2015

The latent dementia phenotype δ is associated with cerebrospinal fluid biomarkers of Alzheimer's disease and predicts conversion to dementia in subjects with mild cognitive impairment.
Koppara, A., Wolfsgruber, S., Kleineidam, L., Schmidtke, K., Froelich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F.M., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Pantel, J., Rienhoff, O., Ruether, E., Henn, F., Wiltfang, J., Maier, W., Jessen, F., Kornhuber, J. and Wagner, M.
Journal of Alzheimer's Disease 49 (2): 547-560. 17 October 2015

Validation of the Erlangen score algorithm for the prediction of the development of dementia due to Alzheimer's disease in pre-dementia subjects.
Lewczuk, P., Kornhuber, J., Toledo, J.B., Trojanowski, J.Q., Knapik-Czajka, M., Peters, O., Wiltfang, J. and Shaw, L.M.
Journal of Alzheimer's Disease 48 (2): 433-441. 9 September 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.
Jansen, W.J., Ossenkoppele, R., Knol, D.L., Tijms, B.M., Scheltens, P., Verhey, F.R.J. and Visser, P.J.
JAMA: Journal of the American Medical Association 313 (19): 1924-1938. 19 May 2015

Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study.
Morgen, K., Schneider, M., Frölich, L., Tost, H., Plichta, M.M., Kölsch, H., Rakebrandt, F., Rienhoff, O., Jessen, F., Peters, O., Jahn, H., Luckhaus, C., Hüll, M., Gertz, H.J., Schröder, J., Hampel, H., Teipel, S.J., Pantel, J., Heuser, I., Wiltfang, J., Rüther, E., Kornhuber, J., Maier, W. and Meyer-Lindenberg, A.
Alzheimer's Research & Therapy 7 (1): 27. 15 May 2015

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage.
Vos, S.J.B., Verhey, F., Froelich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Ruether, E., Nobili, F., Morbelli, S., Frisoni, G.B., Drzezga, A., Didic, M., van Berckel, B.N.M., Simmons, A., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Muscio, C., Herukka, S.K., Salmon, E., Bastin, C., Wallin, A., Nordlund, A., de Mendonca, A., Silva, D., Santana, I., Lemos, R., Engelborghs, S., Van der Mussele, S., Freund-Levi, Y., Wallin, A.K., Hampel, H., van der Flier, W., Scheltens, P. and Visser, P.J.
Brain 138 (Pt 5): 1327-1338. May 2015

PLD3 in non-familial Alzheimer's disease.
Heilmann, S., Drichel, D., Clarimon, J., Fernández, V., Lacour, A., Wagner, H., Thelen, M., Hernández, I., Fortea, J., Alegret, M., Blesa, R., Mauleón, A., Roca, M.R., Kornhuber, J., Peters, O., Heun, R., Frölich, L., Hüll, M., Heneka, M.T., Rüther, E., Riedel-Heller, S., Scherer, M., Wiltfang, J., Jessen, F., Becker, T., Tárraga, L., Boada, M., Maier, W., Lleó, A., Ruiz, A., Nöthen, M.M. and Ramirez, A.
Nature 520 (7545): E3-E5. 2 April 2015

Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI.
Wolfsgruber, S., Jessen, F., Koppara, A., Kleineidam, L., Schmidtke, K., Froelich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F.M., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Pantel, J., Rienhoff, O., Ruether, E., Henn, F., Wiltfang, J., Maier, W., Kornhuber, J. and Wagner, M.
Neurology 84 (12): 1261-1268. 24 March 2015

The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease.
Louwersheimer, E., Ramirez, A., Cruchaga, C., Becker, T., Kornhuber, J., Peters, O., Heilmann, S., Wiltfang, J., Jessen, F., Visser, P.J., Scheltens, P., Pijnenburg, Y.A.L., Teunissen, C.E., Barkhof, F., van Swieten, J.C., Holstege, H. and van der Flier, W.M.
Neurobiology of Aging 36 (3): 1605.e13-1605.e20. March 2015

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type.
Popp, J., Wolfsgruber, S., Heuser, I., Peters, O., Huell, M., Schroeder, J., Moeller, H.J., Lewczuk, P., Schneider, A., Jahn, H., Luckhaus, C., Perneczky, R., Froelich, L., Wagner, M., Maier, W., Wiltfang, J., Kornhuber, J. and Jessen, F.
Neurobiology of Aging 36 (2): 601-607. February 2015

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey.
Bocchetta, M., Galluzzi, S., Kehoe, P.G., Aguera, E., Bernabei, R., Bullock, R., Ceccaldi, M., Dartigues, J.F., de Mendonca, A., Didic, M., Eriksdotter, M., Felician, O., Froelich, L., Gertz, H.J., Hallikainen, M., Hasselbalch, S.G., Hausner, L., Heuser, I., Jessen, F., Jones, R.W., Kurz, A., Lawlor, B., Lleo, A., Martinez-Lage, P., Mecocci, P., Mehrabian, S., Monsch, A., Nobili, F., Nordberg, A., Rikkert, M.O., Orgogozo, J.M., Pasquier, F., Peters, O., Salmon, E., Sanchez-Castellano, C., Santana, I., Sarazin, M., Traykov, L., Tsolaki, M., Visser, P.J., Wallin, A.K., Wilcock, G., Wilkinson, D., Wolf, H., Yener, G., Zekry, D. and Frisoni, G.B.
Alzheimer's & Dementia 11 (2): 195-206. February 2015

Alzheimer amyloid Peptide aβ42 regulates gene expression of transcription and growth factors.
Barucker, C., Sommer, A., Beckmann, G., Eravci, M., Harmeier, A., Schipke, C.G., Brockschnieder, D., Dyrks, T., Althoff, V., Fraser, P.E., Hazrati, L.N., St George-Hyslop, P., Breitner, J.C.S., Peters, O. and Multhaup, G.
Journal of Alzheimer's Disease 44 (2): 613-624. 1 January 2015

2014

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
Ramirez, A., van der Flier, W.M., Herold, C., Ramonet, D., Heilmann, S., Lewczuk, P., Popp, J., Lacour, A., Drichel, D., Louwersheimer, E., Kummer, M.P., Cruchaga, C., Hoffmann, P., Teunissen, C., Holstege, H., Kornhuber, J., Peters, O., Naj, A.C., Chouraki, V., Bellenguez, C., Gerrish, A., Heun, R., Froelich, L., Huell, M., Buscemi, L., Herms, S., Koelsch, H., Scheltens, P., Breteler, M.M., Ruether, E., Wiltfang, J., Goate, A., Jessen, F., Maier, W., Heneka, M.T., Becker, T. and Noethen, M.M.
Human Molecular Genetics 23 (24): 6644-6658. 15 December 2014

Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes.
Thelen, M., Razquin, C., Hernandez, I., Gorostidi, A., Sanchez-Valle, R., Ortega-Cubero, S., Wolfsgruber, S., Drichel, D., Fliessbach, K., Duenkel, T., Damian, M., Heilmann, S., Slotosch, A., Lennarz, M., Seijo-Martinez, M., Rene, R., Kornhuber, J., Peters, O., Luckhaus, C., Jahn, H., Huell, M., Ruether, E., Wiltfang, J., Lorenzo, E., Gascon, J., Lleo, A., Llado, A., Campdelacreu, J., Moreno, F., Ahmadzadehfar, H., Fortea, J., Indakoetxea, B., Heneka, M.T., Wetter, A., Pastor, M.A., Riverol, M., Becker, T., Froelich, L., Tarraga, L., Boada, M., Wagner, M., Jessen, F., Maier, W., Clarimon, J., Lopez de Munain, A., Ruiz, A., Pastor, P. and Ramirez, A.
Neurobiology of Aging 35 (11): 2657.e13-2657.e19. November 2014

The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.
Hooli, B.V., Parrado, A.R., Mullin, K., Yip, W.K., Liu, T., Roehr, J.T., Qiao, D., Jessen, F., Peters, O., Becker, T., Ramirez, A., Lange, C., Bertram, L. and Tanzi, R.E.
Neurology 83 (15): 1353-1358. 7 October 2014

Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease.
Morgen, K., Ramirez, A., Froelich, L., Tost, H., Plichta, M.M., Koelsch, H., Rakebrandt, F., Rienhoff, O., Jessen, F., Peters, O., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Hampel, H., Teipel, S.J., Pantel, J., Heuser, I., Wiltfang, J., Ruether, E., Kornhuber, J., Maier, W. and Meyer-Lindenberg, A.
Alzheimer's & Dementia 10 (5 Suppl): S269-S276. October 2014

Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment.
Wolfsgruber, S., Wagner, M., Schmidtke, K., Froelich, L., Kurz, A., Schulz, S., Hampel, H., Heuser, I., Peters, O., Reischies, F.M., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Pantel, J, Rienhoff, O., Ruether, E., Henn, F., Wiltfang, J., Maier, W., Kornhuber, J. and Jessen, F.
PLoS ONE 9 (7): e100812. 14 July 2014

2013

Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism.
de Souza Silva, M.A., Lenz, B., Rotter, A., Biermann, T., Peters, O., Ramirez, A., Jessen, F., Maier, W., Huell, M., Schroeder, J., Froelich, L., Teipel, S., Gruber, O., Kornhuber, J., Huston, J.P., Mueller, C.P. and Schaeble, S.
Proceedings of the National Academy of Sciences of the United States of America 110 (37): 15097-15102. 10 September 2013

APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease.
Morgen, K., Froelich, L., Tost, H., Plichta, M.M., Koelsch, H., Rakebrandt, F., Rienhoff, O., Jessen, F., Peters, O., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Hampel, H., Teipel, S.J., Pantel, J., Heuser, I., Wiltfang, J., Ruether, E., Kornhuber, J., Maier, W. and Meyer-Lindenberg, A.
Journal of Alzheimer's Disease 37 (2): 389-401. 3 July 2013

Liquordiagnostik bei Demenzen [CSF biomarkers in dementia].
Peters, O. and Schipke, C.G.
Nervenheilkunde 32 (10): 733-736. 2013

2012

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.
Vom Berg, J., Prokop, S., Miller, K.R., Obst, J., Kaelin, R.E., Lopategui-Cabezas, I., Wegner, A., Mair, F., Schipke, C.G., Peters, O., Winter, Y., Becher, B. and Heppner, F.L.
Nature Medicine 18 (12): 1812-1819. December 2012

Morbus Alzheimer: Sind nicht-steroidale Antiphlogistika und Steroide wirksam? [Alzheimer's disease: are non-steroidal anti-inflammatory drugs effective?].
Peters, O.
Deutsche Medizinische Wochenschrift 137 (50): 2627. December 2012

A polymorphic microsatellite repeat within the ECE-1c promoter is involved in transcriptional start site determination, human evolution, and Alzheimer's disease.
Li, Y., Seidel, K., Marschall, P., Klein, M., Hope, A., Schacherl, J., Schmitz, J., Menk, M., Schefe, J.H., Reinemund, J., Hugel, R., Walden, P., Schlosser, A., Volkmer, R., Schimkus, J., Koelsch, H., Maier, W., Kornhuber, J., Froelich, L., Klare, S., Kirsch, S., Schmerbach, K., Scheele, S., Grittner, U., Zollmann, F., Goldin-Lang, P., Peters, O., Kintscher, U., Unger, T. and Funke-Kaiser, H.
Journal of Neuroscience 32 (47): 16807-16820. 21 November 2012

Impact of beta-amyloid-specific florbetaben PET imaging on confidence in early diagnosis of Alzheimer's disease.
Schipke, C.G., Peters, O., Heuser, I., Grimmer, T., Sabbagh, M.N., Sabri, O., Hock, C., Kunz, M., Kuhlmann, J., Reininger, C. and Blankenburg, M.
Dementia and Geriatric Cognitive Disorders 33 (6): 416-422. August 2012

A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI.
Peters, O., Lorenz, D., Fesche, A., Schmidtke, K., Hull, M., Perneczky, R., Ruether, E., Moeller, H.J., Jessen, F., Maier, W., Kornhuber, J., Jahn, H., Luckhaus, C., Gertz, H.J., Schroeder, J., Pantel, J., Teipel, S., Wellek, S., Froelich, L. and Heuser, I.
Journal of Nutrition Health & Aging 16 (6): 544-548. June 2012

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann, S.M., Krueger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., Trimbuch, T., Eom, G., Hinz, M., Kaul, D., Habbel, P., Kaelin, R., Franzoni, E., Rybak, A., Nguyen, D., Veh, R., Ninnemann, O., Peters, O., Nitsch, R., Heppner, F.L., Golenbock, D., Schott, E., Ploegh, H.L., Wulczyn, F.G. and Lehnardt, S.
Nature Neuroscience 15 (6): 827-835. June 2012

Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease.
Wagner, M., Wolf, S., Reischies, F.M., Daerr, M., Wolfsgruber, S., Jessen, F., Popp, J., Maier, W., Huell, M., Froelich, L., Hampel, H., Perneczky, R., Peters, O., Jahn, H., Luckhaus, C., Gertz, H.J., Schroeder, J., Pantel, J., Lewczuk, P., Kornhuber, J. and Wiltfang, J.
Neurology 78 (6): 379-386. 7 February 2012

Genome-wide association study of vascular dementia.
Schrijvers, E.M., Schuermann, B., Koudstaal, P.J., van den Bussche, H., Van Duijn, C.M., Hentschel, F., Heun, R., Hofman, A., Jessen, F., Koelsch, H., Kornhuber, J., Peters, O., Rivadeneira, F., Ruether, E., Uitterlinden, A.G., Riedel-Heller, S., Dichgans, M., Wiltfang, J., Maier, W., Breteler, M.M.B. and Ikram, M.A.
Stroke 43 (2): 315-319. February 2012

2011

Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment.
Frings, L., Kloeppel, S., Teipel, S., Peters, O., Froelich, L., Pantel, J., Schroeder, J., Gertz, H.J., Arlt, S., Heuser, I., Kornhuber, J., Wiltfang, J., Maier, W., Jessen, F., Hampel, H. and Huell, M.
Current Alzheimer Research 8 (8): 893-901. December 2011

Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: effect of different processing and analysis approaches on sample sizes.
Teipel, S.J., Peters, O., Heuser, I., Jessen, F., Maier, W., Froelich, L., Arlt, S., Huell, M., Gertz, H.J., Kornhuber, J., Wiltfang, J., Thome, J., Rienhoff, O., Meindl, T., Hampel, H. and Grothe, M.
World Journal of Biological Psychiatry 12 (Suppl 1): 109-113. September 2011

Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study.
Barthel, H., Gertz, H.J., Dresel, S., Peters, O., Bartenstein, P., Buerger, K., Hiemeyer, F., Wittemer-Rump, S.M., Seibyl, J., Reininger, C. and Sabri, O.
Lancet Neurology 10 (5): 424-435. May 2011

Comparison of immunosorbent assays for the quantification of biomarkers for Alzheimer's disease in human cerebrospinal fluid.
Schipke, C.G., Prokop, S., Heppner, F.L., Heuser, I. and Peters, O.
Dementia and Geriatric Cognitive Disorders 31 (2): 139-145. March 2011

Antidepressants act on glial cells: SSRIs and serotonin elicit astrocyte calcium signaling in the mouse prefrontal cortex.
Schipke, C.G., Heuser, I. and Peters, O.
Journal of Psychiatric Research 45 (2): 242-248. February 2011

Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia.
Jessen, F., Lewczuk, P., Guer, O., Block, W., Ende, G., Froelich, L., Hammen, T., Arlt, S., Kornhuber, J., Kucinski, T., Popp, J., Peters, O., Maier, W., Traeber, F. and Wiltfang, J.
Journal of Alzheimer's Disease 27 (2): 393-399. 2011

Long-term stability of Alzheimer's disease biomarker proteins in cerebrospinal fluid.
Schipke, C.G., Jessen, F., Teipel, S., Luckhaus, C., Wiltfang, J., Esselmann, H., Froelich, L., Maier, W., Ruether, E., Heppner, F.L., Prokop, S., Heuser, I. and Peters, O.
Journal of Alzheimer's Disease 26 (2): 255-262. 2011

2010

A novel MRI-biomarker candidate for Alzheimer's disease composed of regional brain volume and perfusion variables.
Luckhaus, C., Jaenner, M., Cohnen, M., Fluess, M.O., Teipel, S.J., Grothe, M., Hampel, H., Kornhuber, J., Ruether, E., Peters, O., Supprian, T., Gaebel, W., Moedder, U. and Wittsack, H.J.
European Journal of Neurology 17 (12): 1437-1444. December 2010

The relation of regional cerebral perfusion and atrophy in mild cognitive impairment (MCI) and early Alzheimer's dementia.
Luckhaus, C., Cohnen, M., Fluess, M.O., Jaenner, M., Grass-Kapanke, B., Teipel, S.J., Grothe, M., Hampel, H., Peters, O., Kornhuber, J., Maier, W., Supprian, T., Gaebel, W., Moedder, U. and Wittsack, H.J.
Psychiatry Research 183 (1): 44-51. 30 July 2010

Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease.
Teipel, S.J., Ewers, M., Wolf, S., Jessen, F., Koelsch, H., Arlt, S., Luckhaus, C., Schoenknecht, P., Schmidtke, K., Heuser, I., Froelich, L., Ende, G., Pantel, J., Wiltfang, J., Rakebrandt, F., Peters, O., Born, C., Kornhuber, J. and Hampel, H.
Psychiatry Research 182 (3): 244-250. 30 June 2010

Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: a multicenter study with multiplexing.
Lewczuk, P., Kornhuber, J., Vanmechelen, E., Peters, O., Heuser, I., Maier, W., Jessen, F., Buerger, K., Hampel, H., Froelich, L., Henn, F., Falkai, P., Ruether, E., Jahn, H., Luckhaus, C., Perneczky, R., Schmidtke, K., Schroeder, J., Kessler, H., Pantel, J., Gertz, H.J., Vanderstichele, H., de Meyer, G., Shapiro, F., Wolf, S., Bibl, M. and Wiltfang, J.
Experimental Neurology 223 (2): 366-370. June 2010

Neuropsychologische Therapie. Grundlagen und Praxis der Behandlung kognitiver Stoerungen bei neurologischen Erkrankungen [Neuropsychological therapy. Fundamentals and practice of the treatments on cognitive disorders in neurological disease].
Beinhoff, U., Buhrsch, N. and Peters, O.
Neuroforum 16 (2): 205-206. June 2010

Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study.
Lewczuk, P., Kamrowski-Kruck, H., Peters, O., Heuser, I., Jessen, F., Popp, J., Buerger, K., Hampel, H., Froelich, L., Wolf, S., Prinz, B., Jahn, H., Luckhaus, C., Perneczky, R., Huell, M., Schroeder, J., Kessler, H., Pantel, J., Gertz, H.J., Klafki, H.W., Koelsch, H., Reulbach, U., Esselmann, H., Maler, J.M., Bibl, M., Kornhuber, J. and Wiltfang, J.
Molecular Psychiatry 15 (2): 138-145. February 2010

2009

A possible new diagnostic biomarker in early diagnosis of Alzheimer's disease.
Kork, F., Holthues, J., Hellweg, R., Jankowski, V., Tepel, M., Ohring, R., Heuser, I., Bierbrauer, J., Peters, O., Schlattmann, P., Zidek, W. and Jankowski, J.
Current Alzheimer Research 6 (6): 519-524. December 2009

Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network.
Kornhuber, J., Schmidtke, K., Froelich, L., Perneczky, R., Wolf, S., Hampel, H., Jessen, F., Heuser, I., Peters, O., Weih, M., Jahn, H., Luckhaus, C., Huell, M., Gertz, H.J., Schroeder, J., Pantel, J., Rienhoff, O., Seuchter, S.A., Ruether, E., Henn, F., Maier, W. and Wiltfang, J.
Dementia and Geriatric Cognitive Disorders 27 (5): 404-417. June 2009

Association of SORL1 gene variants with Alzheimer's disease.
Koelsch, H., Jessen, F., Wiltfang, J., Lewczuk, P., Dichgans, M., Teipel, S.J., Kornhuber, J., Froelich, L., Heuser, I., Peters, O., Wiese, B., Kaduszkiewicz, H., van den Bussche, H., Huell, M., Kurz, A., Ruether, E., Henn, F.A. and Maier, W.
Brain Research 1264 : 1-6. 6 April 2009

Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia.
Alexopoulos, P., Guenther, F., Popp, J., Jessen, F., Peters, O., Wolf, S., Kneib, T., Kurz, A., Richter-Schmidinger, T., Lewczuk, P., Bleich, S., Wiltfang, J. and Kornhuber, J.
Journal of the American Geriatrics Society 57 (4): 737-739. April 2009

Astrocyte function is modified by Alzheimer's disease-like pathology in aged mice.
Peters, O., Schipke, C.G., Philipps, A., Haas, B., Pannasch, U., Wang, L.P., Benedetti, B., Kingston, A.E. and Kettenmann, H.
Journal of Alzheimer's Disease 18 (1): 177-189. 2009

Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form.
Klafki, H.W., Lewczuk, P., Kamrowski-Kruck, H., Maler, J.M., Mueller, K., Peters, O., Heuser, I., Jessen, F., Popp, J., Froelich, L., Wolf, S., Prinz, B., Luckhaus, C., Schroeder, J., Pantel, J., Gertz, H.J., Koelsch, H., Mueller, B.W., Esselmann, H., Bibl, M., Kornhuber, J. and Wiltfang, J.
Journal of Alzheimer's Disease 18 (3): 613-622. 2009

2008

Influence of SORL1 gene variants: association with CSF amyloid-β products in probable Alzheimer's disease.
Koelsch, H., Jessen, F., Wiltfang, J., Lewczuk, P., Dichgans, M., Kornhuber, J., Froelich, L., Heuser, I., Peters, O., Schulz, J.B., Schwab, S.G. and Maier, W.
Neuroscience Letters 440 (1): 68-71. 25 July 2008

Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study.
Lewczuk, P., Kornhuber, J., Vanderstichele, H., Vanmechelen, E., Esselmann, H., Bibl, M., Wolf, S., Otto, M., Reulbach, U., Koelsch, H., Jessen, F., Schroeder, J., Schoenknecht, P., Hampel, H., Peters, O., Weimer, E., Perneczky, R., Jahn, H., Luckhaus, C., Lamla, U., Supprian, T., Maler, J.M. and Wiltfang, J.
Neurobiology of Aging 29 (6): 812-818. June 2008

Temperature and nitric oxide control spontaneous calcium transients in astrocytes.
Schipke, C.G., Heidemann, A., Skupin, A., Peters, O., Falcke, M. and Kettenmann, H.
Cell Calcium 43 (3): 285-295. March 2008

2007

Amyloidβ peptide ratio 42/40 but not Aβ42 correlates with phospho-Tau in patients with low- and high-CSF Aβ40 load.
Wiltfang, J., Esselmann, H., Bibl, M., Huell, M., Hampel, H., Kessler, H., Froelich, L., Schroeder, J., Peters, O., Jessen, F., Luckhaus, C., Perneczky, R., Jahn, H., Fiszer, M., Maler, J.M., Zimmermann, R., Bruckmoser, R., Kornhuber, J. and Lewczuk, P.
Journal of Neurochemistry 101 (4): 1053-1059. May 2007

2006

Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves.
Haas, B., Schipke, C.G., Peters, O., Soehl, G., Willecke, K. and Kettenmann, H.
Cerebral Cortex 16 (2): 237-246. February 2006

2005

Increased extracellular K+ concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression-like depolarizations and spreading ischemia.
Petzold, G.C., Windmueller, O., Haack, S., Major, S., Buchheim, K., Megow, D., Gabriel, S., Lehmann, T.N., Drenckhahn, C., Peters, O., Meierkord, H., Heinemann, U., Dirnagl, U. and Dreier, J.P.
Stroke 36 (6): 1270-1277. June 2005

Zinc ions are endogenous modulators of neurotransmitter-stimulated capacitative Ca2+ entry in both cultured and in situ mouse astrocytes.
Kresse, W., Sekler, I., Hoffmann, A., Peters, O., Nolte, C., Moran, A. and Kettenmann, H.
European Journal of Neuroscience 21 (6): 1626-1634. 1 January 2005

Combination therapy in dementia [Antidementive kombinationstherapie].
Peters, O., Froelich, L. and Heuser, I.
Nervenheilkunde 24 (6): 476-482. 2005

2004

Impaired synaptic plasticity in the surround of perinatally acquired dysplasia in rat cerebral cortex.
Peters, O., Redecker, C., Hagemann, G., Bruehl, C., Luhmann, H.J. and Witte, O.W.
Cerebral Cortex 14 (10): 1081-1087. October 2004

2003

Different mechanisms promote astrocyte Ca2+ waves and spreading depression in the mouse neocortex.
Peters, O., Schipke, C.G., Hashimoto, Y. and Kettenmann, H.
Journal of Neuroscience 23 (30): 9888-9896. 29 October 2003

2001

Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain.
Jander, S., Schroeter, M., Peters, O., Witte, O.W. and Stoll, G.
Journal of Cerebral Blood Flow and Metabolism 21 (3): 218-225. March 2001

1998

Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat.
Peters, O., Back, T., Lindauer, U., Busch, C., Megow, D., Dreier, J. and Dirnagl, U.
Journal of Cerebral Blood Flow and Metabolism 18 (2): 196-205. February 1998