Browse by Journal Title

2024

Mechanistic insights into the basis of widespread RNA localization.
Chekulaeva, M.
Nature Cell Biology 26 (7): 1037-1046. July 2024

Extraembryonic gut endoderm cells undergo programmed cell death during development.
Batki, J., Hetzel, S., Schifferl, D., Bolondi, A., Walther, M., Wittler, L., Grosswendt, S., Herrmann, B.G. and Meissner, A.
Nature Cell Biology 26 (6): 868-877. June 2024

Next questions in autophagy.
Cuervo, A.M., Elazar, Z., Evans, C., Ge, L., Hansen, M., Jäättelä, M., Liang, J.R.A., Loos, B., Mizushima, N., Simon, A.K., Tooze, S., Yoshimori, T. and Nakamura, S.
Nature Cell Biology 26 (5): 661-666. May 2024

2023

Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert, R., Hetzel, S., Bailly, N., Haggerty, C., Ilik, I.A., Yung, P.Y.K., Navarro, C., Bolondi, A., Kumar, A.S., Anania, C., Brändl, B., Meierhofer, D., Lupianez, D.G., Müller, F.J., Aktas, T., Elsässer, S.J., Kretzmer, H., Smith, Z.D. and Meissner, A.
Nature Cell Biology 25 : 579–591. April 2023

A guide to naming eukaryotic circular RNAs.
Chen, L.L., Bindereif, A., Bozzoni, I., Chang, H.Y., Matera, A.G., Gorospe, M., Hansen, T.B., Kjems, J., Ma, X.K., Pek, J.W., Rajewsky, N., Salzman, J., Wilusz, J.E., Yang, L. and Zhao, F.
Nature Cell Biology 25 (1): 1-5. January 2023

2022

Proton-gated anion transport governs macropinosome shrinkage.
Zeziulia, M., Blin, S., Schmitt, F.W., Lehmann, M. and Jentsch, T.J.
Nature Cell Biology 24 (6): 885-895. June 2022

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation.
Blassberg, R., Patel, H., Watson, T., Gouti, M., Metzis, V., Delás, M.J. and Briscoe, J.
Nature Cell Biology 24 (5): 633-644. May 2022

2021

Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
Cereghetti, G., Wilson-Zbinden, C., Kissling, V.M., Diether, M., Arm, A., Yoo, H., Piazza, I., Saad, S., Picotti, P., Drummond, D.A., Sauer, U., Dechant, R. and Peter, M.
Nature Cell Biology 23 (10): 1085-1094. October 2021

Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis.
Moreno-Layseca, P., Jäntti, N.Z., Godbole, R., Sommer, C., Jacquemet, G., Al-Akhrass, H., Conway, J.R.W., Kronqvist, P., Kallionpää, R.E., Oliveira-Ferrer, L., Cervero, P., Linder, S., Aepfelbacher, M., Zauber, H., Rae, J., Parton, R.G., Disanza, A., Scita, G., Mayor, S., Selbach, M., Veltel, S. and Ivaska, J.
Nature Cell Biology 23 (10): 1073-1084. October 2021

Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility.
Koester, J., Miroshnikova, Y.A., Ghatak, S., Chacón-Martínez, C.A., Morgner, J., Li, X., Atanassov, I., Altmüller, J., Birk, D.E., Koch, M., Bloch, W., Bartusel, M., Niessen, C.M., Rada-Iglesias, A. and Wickström, S.A.
Nature Cell Biology 23 (7): 771-781. July 2021

Control of endothelial quiescence by FOXO-regulated metabolites.
Andrade, J., Shi, C., Costa, A.S.H., Choi, J., Kim, J., Doddaballapur, A., Sugino, T., Ong, Y.T., Castro, M., Zimmermann, B., Kaulich, M., Guenther, S., Wilhelm, K., Kubota, Y., Braun, T., Koh, G.Y., Grosso, A.R., Frezza, C. and Potente, M.
Nature Cell Biology 23 : 413-423. April 2021

Depletion of aneuploid cells in human embryos and gastruloids.
Yang, M., Rito, T., Metzger, J., Naftaly, J., Soman, R., Hu, J., Albertini, D.F., Barad, D.H., Brivanlou, A.H. and Gleicher, N.
Nature Cell Biology 23 (4): 314-321. April 2021

2020

Beth Levine 1960-2020.
Simon, A.K. and Mizushima, N.
Nature Cell Biology 22 (8): 909-910. August 2020

AP-1 imprints a reversible transcriptional programme of senescent cells.
Martínez-Zamudio, R.I., Roux, P.F., de Freitas, J.A.N.L.F., Robinson, L., Doré, G., Sun, B., Belenki, D., Milanovic, M., Herbig, U., Schmitt, C.A., Gil, J. and Bischof, O.
Nature Cell Biology 22 (7): 842-855. July 2020

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
Müller, P.M., Rademacher, J., Bagshaw, R.D., Wortmann, C., Barth, C., van Unen, J., Alp, K.M., Giudice, G., Eccles, R.L., Heinrich, L.E., Pascual-Vargas, P., Sanchez-Castro, M., Brandenburg, L., Mbamalu, G., Tucholska, M., Spatt, L., Czajkowski, M.T., Welke, R.W., Zhang, S., Nguyen, V., Rrustemi, T., Trnka, P., Freitag, K., Larsen, B., Popp, O., Mertins, P., Gingras, A.C., Roth, F.P., Colwill, K., Bakal, C., Pertz, O., Pawson, T., Petsalaki, E. and Rocks, O.
Nature Cell Biology 22 (4): 498-511. April 2020

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization.
Baccin, C., Al-Sabah, J., Velten, L., Helbling, P.M., Grünschläger, F., Hernández-Malmierca, P., Nombela-Arrieta, C., Steinmetz, L.M., Trumpp, A. and Haas, S.
Nature Cell Biology 22 (1): 38-48. January 2020

2019

A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.
Sharir, A., Marangoni, P., Zilionis, R., Wan, M., Wald, T., Hu, J.K., Kawaguchi, K., Castillo-Azofeifa, D., Epstein, L., Harrington, K., Pagella, P., Mitsiadis, T., Siebel, C.W., Klein, A.M. and Klein, O.D.
Nature Cell Biology 21 (9): 1102-1112. September 2019

R-spondin-3 induces secretory, antimicrobial Lgr5(+) cells in the stomach.
Sigal, M., Del Mar Reinés, M., Müllerke, S., Fischer, C., Kapalczynska, M., Berger, H., Bakker, E.R.M., Mollenkopf, H.J., Rothenberg, M.E., Wiedenmann, B., Sauer, S. and Meyer, T.F.
Nature Cell Biology 21 (7): 812-823. July 2019

A 3D model of a human epiblast reveals BMP4-driven symmetry breaking.
Simunovic, M., Metzger, J.J., Etoc, F., Yoney, A., Ruzo, A., Martyn, I., Croft, G., You, D.S., Brivanlou, A.H. and Siggia, E.D.
Nature Cell Biology 21 (7): 900-910. July 2019

The dynamic nature of senescence in cancer.
Lee, S. and Schmitt, C.A.
Nature Cell Biology 21 (1): 94-101. January 2019

2018

Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon(+) α-cells.
Cigliola, V., Ghila, L., Thorel, F., van Gurp, L., Baronnier, D., Oropeza, D., Gupta, S., Miyatsuka, T., Kaneto, H., Magnuson, M.A., Osipovich, A.B., Sander, M., Wright, C.E.V., Thomas, M.K., Furuyama, K., Chera, S. and Herrera, P.L.
Nature Cell Biology 20 (11): 1267-1277. November 2018

2017

Human haematopoietic stem cell lineage commitment is a continuous process.
Velten, L., Haas, S.F., Raffel, S., Blaszkiewicz, S., Islam, S., Hennig, B.P., Hirche, C., Lutz, C., Buss, E.C., Nowak, D., Boch, T., Hofmann, W.K., Ho, A.D., Huber, W., Trumpp, A., Essers, M.A.G. and Steinmetz, L.M.
Nature Cell Biology 19 (4): 271-281. April 2017

2016

Asymmetric division coordinates collective cell migration in angiogenesis.
Costa, G., Harrington, K.I., Lovegrove, H.E., Page, D.J., Chakravartula, S., Bentley, K. and Herbert, S.P.
Nature Cell Biology 18 (12): 1292-1301. December 2016

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Kaminski, M.M., Tosic, J., Kresbach, C., Engel, H., Klockenbusch, J., Müller, A.L., Pichler, R., Grahammer, F., Kretz, O., Huber, T.B., Walz, G., Arnold, S.J. and Lienkamp, S.S.
Nature Cell Biology 18 (12): 1269-1280. December 2016

The persistent dynamic secrets of senescence.
Schmitt, C.A.
Nature Cell Biology 18 (9): 913-915. September 2016

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment.
Le, H.Q., Ghatak, S., Yeung, C.Y.C., Tellkamp, F., Günschmann, C., Dieterich, C., Yeroslaviz, A., Habermann, B., Pombo, A., Niessen, C.M. and Wickström, S.A.
Nature Cell Biology 18 (8): 864-875. August 2016

Orchestrating Wnt signalling for metabolic liver zonation.
Birchmeier, W.
Nature Cell Biology 18 (5): 463-465. May 2016

Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo.
Gebala, V., Collins, R., Geudens, I., Phng, L.K. and Gerhardt, H.
Nature Cell Biology 18 (4): 443-450. April 2016

Stem cells versus plasticity in liver and pancreas regeneration.
Kopp, J.L., Grompe, M. and Sander, M.
Nature Cell Biology 18 (3): 238-45. March 2016

2015

In vivo reprogramming for tissue repair.
Heinrichs, C., Spagnoli, F.M. and Berninger, B.
Nature Cell Biology 17 (3): 204-211. 27 February 2015

2014

Rsp5/Nedd4 clears cells of heat-damaged proteins.
Sommer, T., Weber, A. and Jarosch, E.
Nature Cell Biology 16 (12): 1130-1132. 1 December 2014

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.
Bentley, K., Franco, C.A., Philippides, A., Blanco, R., Dierkes, M., Gebala, V., Stanchi, F., Jones, M., Aspalter, I.M., Cagna, G., Weström, S., Claesson-Welsh, L., Vestweber, D. and Gerhardt, H.
Nature Cell Biology 16 (4): 309-321. April 2014

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane.
Mehnert, M., Sommer, T. and Jarosch, E.
Nature Cell Biology 16 (1): 77-86. January 2014

2013

SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.
Fernández-Sáiz, V., Targosz, B.S., Lemeer, S., Eichner, R., Langer, C., Bullinger, L., Reiter, C., Slotta-Huspenina, J., Schroeder, S., Knorn, A.M., Kurutz, J., Peschel, C., Pagano, M., Kuster, B. and Bassermann, F.
Nature Cell Biology 15 (1): 72-81. January 2013

2012

Diverse epigenetic strategies interact to control epidermal differentiation.
Mulder, K.W., Wang, X., Escriu, C., Ito, Y., Schwarz, R.F., Gillis, J., Sirokmany, G., Donati, G., Uribe-Lewis, S., Pavlidis, P., Murrell, A., Markowetz, F. and Watt, F.M.
Nature Cell Biology 14 (7): 753-763. 24 June 2012

2011

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.
Tammela, T., Zarkada, G., Nurmi, H., Jakobsson, L., Heinolainen, K., Tvorogov, D., Zheng, W., Franco, C.A., Murtomäki, A., Aranda, E., Miura, N., Ylä-Herttuala, S., Fruttiger, M., Mäkinen, T., Eichmann, A., Pollard, J.W., Gerhardt, H. and Alitalo, K.
Nature Cell Biology 13 (10): 1202-1213. 11 September 2011

FOXO1 is an essential regulator of pluripotency in human embryonic stem cells.
Zhang, X., Yalcin, S., Lee, D.F., Yeh, T.Y., Lee, S.M., Su, J., Mungamuri, S.K., Rimmele, P., Kennedy, M., Sellers, R., Landthaler, M., Tuschl, T., Chi, N.W., Lemischka, I., Keller, G. and Ghaffari, S.
Nature Cell Biology 13 (9): 1092-1099. 31 July 2011

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.
Di Micco, R., Sulli, G., Dobreva, M., Liontos, M., Botrugno, O.A., Gargiulo, G., dal Zuffu, R., Matti, V., d'Ario, G., Montani, E., Mercurio, C., Hahn, W.C., Gorgoulis, V., Minucci, S. and d'Adda di Fagagna, F.
Nature Cell Biology 13 (3): 292-302. March 2011

2010

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.
Jakobsson, L., Franco, C.A., Bentley, K., Collins, R.T., Ponsioen, B., Aspalter, I.M., Rosewell, I., Busse, M., Thurston, G., Medvinsky, A., Schulte-Merker, S. and Gerhardt, H.
Nature Cell Biology 12 (10): 943-953. October 2010

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.
Landeira, D., Sauer, S., Poot, R., Dvorkina, M., Mazzarella, L., Jorgensen, H.F., Pereira, C.F., Leleu, M., Piccolo, F.M., Spivakov, M., Brookes, E., Pombo, A., Fisher, C., Skarnes, W.C., Snoek, T., Bezstarosti, K., Demmers, J., Klose, R.J., Casanova, M., Tavares, L., Brockdorff, N., Merkenschlager, M. and Fisher, A.G.
Nature Cell Biology 12 (6): 618-624. June 2010

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.
Zaltsman, Y., Shachnai, L., Yivgi-Ohana, N., Schwarz, M., Maryanovich, M., Houtkooper, R.H., Vaz, F.M., De Leonardis, F., Fiermonte, G., Palmieri, F., Gillissen, B., Daniel, P.T., Jimenez, E., Walsh, S., Koehler, C.M., Roy, S.S., Walter, L., Hajnoczky, G. and Gross, A.
Nature Cell Biology 12 (6): 553-562. June 2010

The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells.
Stolz, A., Ertych, N., Kienitz, A., Vogel, C., Schneider, V., Fritz, B., Jacob, R., Dittmar, G., Weichert, W., Petersen, I. and Bastians, H.
Nature Cell Biology 12 (5): 492-499. May 2010

2009

Ageing-related chromatin defects through loss of the NURD complex.
Pegoraro, G., Kubben, N., Wickert, U., Goehler, H., Hoffmann, K. and Misteli, T.
Nature Cell Biology 11 (10): 1261-1267. October 2009

2008

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.
Taddei, A., Giampietro, C., Conti, A., Orsenigo, F., Breviario, F., Pirazzoli, V., Potente, M., Daly, C., Dimmeler, S. and Dejana, E.
Nature Cell Biology 10 (8): 923-934. August 2008

Sirt1 contributes critically to the redox-dependent fate of neural progenitors.
Prozorovski, T., Schulze-Topphoff, U., Glumm, R., Baumgart, J., Schroeter, F., Ninnemann, O., Siegert, E., Bendix, I., Bruestle, O., Nitsch, R., Zipp, F. and Aktas, O.
Nature Cell Biology 10 (4): 385-394. April 2008

2007

Normal brain development in importin-alpha5 deficient-mice.
Shmidt, T., Hampich, F., Ridders, M., Schultrich, S., Hans, V.H., Tenner, K., Vilianovich, L., Qadri, F., Alenina, N., Hartmann, E., Koehler, M. and Bader, M.
Nature Cell Biology 9 (12): 1337-1338. December 2007

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells.
Stock, J.K., Giadrossi, S., Casanova, M., Brookes, E., Vidal, M., Koseki, H., Brockdorff, N., Fisher, A.G. and Pombo, A.
Nature Cell Biology 9 (12): 1428-1435. December 2007

Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
Qi, M.L., Tagawa, K., Enokido, Y., Yoshimura, N., Wada, Y.I., Watase, K., Ishiura, S.I., Kanazawa, I., Botas, J., Saitoe, M., Wanker, E.E. and Okazawa, H.
Nature Cell Biology 9 (4): 402-414. April 2007

2006

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
Gauss, R., Jarosch, E., Sommer, T. and Hirsch, C.
Nature Cell Biology 8 (8): 849-854. August 2006

Chromatin signatures of pluripotent cell lines.
Azuara, V., Perry, P., Sauer, S., Spivakov, M., Jorgensen, H.F., John, R.M., Gouti, M., Casanova, M., Warnes, G., Merkenschlager, M. and Fisher, A.G.
Nature Cell Biology 8 (5): 532-538. May 2006

2005

Ubx2 links the Cdc48 complex to ER-associated protein degradation.
Neuber, O., Jarosch, E., Volkwein, C., Walter, J. and Sommer, T.
Nature Cell Biology 7 (10): 993-998. 18 September 2005

ERAD: the long road to destruction.
Meusser, B., Hirsch, C., Jarosch, E. and Sommer, T.
Nature Cell Biology 7 (8): 766-772. August 2005

2004

Ion channels: function unravelled by dysfunction.
Jentsch, T.J., Huebner, C.A. and Fuhrmann, J.C.
Nature Cell Biology 6 (11): 1039-1047. November 2004

2003

EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation.
Reynolds, A.R., Tischer, C., Verveer, P.J., Rocks, O. and Bastiaens, P.I.
Nature Cell Biology 5 (5): 447-453. May 2003

2002

Proteasome subunit Rpn1 binds ubiquitin-like protein domains.
Elsasser, S., Gali, R.R., Schwickart, M., Larsen, C.N., Leggett, D.S., Mueller, B., Feng, M.T., Tuebing, F., Dittmar, G.A.G. and Finley, D.
Nature Cell Biology 4 : 725-730. 1 September 2002

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Fujita, Y., Krause, G., Scheffner, M., Zechner, D., Leddy, H.E.M., Behrens, J., Sommer, T. and Birchmeier, W.
Nature Cell Biology 4 (3): 222-231. 1 March 2002

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.
Jarosch, E., Taxis, C., Volkwein, C., Bordallo, J., Finley, D., Wolf, D.H. and Sommer, T.
Nature Cell Biology 4 (2): 134-139. 1 February 2002

2000

A regulatory link between ER-associated protein degradation and the unfolded-protein response.
Friedlander, R., Jarosch, E., Urban, J., Volkwein, C. and Sommer, T.
Nature Cell Biology 2 (7): 379-384. 1 July 2000

Smooth-muscle contraction without smooth-muscle myosin.
Morano, I., Chai, G.X., Baltas, L.G., Lamounier-Zepter, V., Lutsch, G., Kott, M., Haase, H. and Bader, M.
Nature Cell Biology 2 (6): 371-375. 1 June 2000

1999

Lipoprotein receptors: new roles for ancient proteins.
Willnow, T.E., Nykjaer, A. and Herz, J.
Nature Cell Biology 1 : E157-E162. 1 October 1999

The base of the proteasome regulatory particle exhibits chaperone-like activity.
Braun, B.C., Glickman, M., Kraft, R., Dahlmann, B., Kloetzel, P.M., Finley, D. and Schmidt, M.
Nature Cell Biology 1 (4): 221-226. 1 August 1999

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.
Kotlyarov, A., Neininger, A., Schubert, C., Eckert, R., Birchmeier, C., Volk, H.D. and Gaestel, M.
Nature Cell Biology 1 : 94-97. 1 June 1999

Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans.
Scheel, J., Srinivasan, J., Honnert, U., Henske, A. and Kurzchalia, T.V.
Nature Cell Biology 1 : 127-129. 1 January 1999