Items where Year is 2016

A

KCNE2 and gastric cancer: bench to bedside.
Abbott, G.W. and Roepke, T.K.
Oncotarget 7 (14): 17286-17287. 5 April 2016

Von Willebrand factor gene variants associate with herpes simplex encephalitis.
Abdelmagid, N., Bereczky-Veress, B., Atanur, S., Musilová, A., Zidek, V., Saba, L., Warnecke, A., Khademi, M., Studahl, M., Aurelius, E., Hjalmarsson, A., Garcia-Diaz, A., Denis, C.V., Bergström, T., Sköldenberg, B., Kockum, I., Aitman, T., Hübner, N., Olsson, T., Pravenec, M. and Diez, M.
PLoS ONE 11 (5): e0155832. 25 May 2016

Personal recollections about N.W. Timoféeff-Ressovsky and his action for radiation biophysics in Berlin-Buch and Dubna.
Abel, H. and Erzgräber, G.
In: Genetics, Evolution and Radiation. Springer, Cham, 33-37. ISBN 978-3-319-48837-0 2016

Radiation risks and confusions.
Abel, H. and Erzgräber, G.
In: Genetics, Evolution and Radiation. Springer, Cham, 187-191. ISBN 978-3-319-48837-0 2016

Structural determinants of sleeping beauty transposase activity.
Abrusán, G., Yant, S.R., Szilágyi, A., Marsh, J.A., Mátés, L., Izsvák, Z., Barabás, O. and Ivics, Z.
Molecular Therapy 24 (8): 1369-1377. August 2016

Exome sequencing identifies biallelic MSH3 germline mutations as a recessive subtype of colorectal adenomatous polyposis.
Adam, R., Spier, I., Zhao, B., Kloth, M., Marquez, J., Hinrichsen, I., Kirfel, J., Tafazzoli, A., Horpaopan, S., Uhlhaas, S., Stienen, D., Friedrichs, N., Altmüller, J., Laner, A., Holzapfel, S., Peters, S., Kayser, K., Thiele, H., Holinski-Feder, E., Marra, G., Kristiansen, G., Nöthen, M.M., Büttner, R., Möslein, G., Betz, R.C., Brieger, A., Lifton, R.P. and Aretz, S.
American Journal of Human Genetics 99 (2): 337-51. 4 August 2016

The metabolic background is a global player in Saccharomyces gene expression epistasis.
Alam, M.T., Zelezniak, A., Mülleder, M., Shliaha, P., Schwarz, R., Capuano, F., Vowinckel, J., Radmaneshfar, E., Krüger, A., Calvani, E., Michel, S., Börno, S., Christen, S., Patil, K.R., Timmermann, B., Lilley, K.S. and Ralser, M.
Nature Microbiology 1 : 15030. 1 February 2016

Circulating omentin as a novel biomarker for colorectal cancer risk: Data from the EPIC - Potsdam cohort study.
Aleksandrova, K., di Giuseppe, R., Isermann, B., Biemann, R., Schulze, M.B., Wittenbecher, C., Fritsche, A., Lehmann, R., Menzel, J., Weikert, C., Pischon, T. and Boeing, H.
Cancer Research 76 (13): 3862-3871. 1 July 2016

Endogenous gibbon ape leukemia virus identified in a rodent (Melomys burtoni subsp.) from Wallacea (Indonesia).
Alfano, N., Michaux, J., Morand, S., Aplin, K., Tsangaras, K., Löber, U., Fabre, P.H., Fitriana, Y., Semiadi, G., Ishida, Y., Helgen, K.M., Roca, A.L., Eiden, M.V. and Greenwood, A.D.
Journal of Virology 90 (18): 8169-8180. 15 September 2016

Standardized benchmarking in the quest for orthologs.
Altenhoff, A.M., Boeckmann, B., Capella-Gutierrez, S., Dalquen, D.A., DeLuca, T., Forslund, K., Huerta-Cepas, J., Linard, B., Pereira, C., Pryszcz, L.P., Schreiber, F., da Silva, A.S., Szklarczyk, D., Train, C.M., Bork, P., Lecompte, O., von Mering, C., Xenarios, I., Sjölander, K., Jensen, L.J., Martin, M.J., Muffato, M., Gabaldón, T., Lewis, S.E., Thomas, P.D., Sonnhammer, E. and Dessimoz, C.
Nature Methods 13 (5): 425-430. May 2016

A systematic comparison of two new releases of exome sequencing products: the aim of use determines the choice of product.
Altmüller, J., Motameny, S., Becker, C., Thiele, H., Chatterjee, S., Wollnik, B. and Nürnberg, P.
Biological Chemistry 397 (8): 791-801. 1 August 2016

Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.
Ammann, S., Schulz, A., Krägeloh-Mann, I., Dieckmann, N.M.G., Niethammer, K., Fuchs, S., Eckl, K.M., Plank, R., Werner, R., Altmüller, J., Thiele, H., Nürnberg, P., Bank, J., Strauss, A., von Bernuth, H., Zur Stadt, U., Grieve, S., Griffiths, G.M., Lehmberg, K., Hennies, H.C. and Ehl, S.
Blood 127 (8): 997-1006. 25 February 2016

ISN Nexus 2016 Symposia: translational immunology in kidney disease -- the Berlin roadmap.
Anders, H.J., Rovin, B., Jayne, D., Brunetta, P., Coppo, R., Davidson, A., Devarapu, S.K., de Zeeuw, D., Duffield, J., Eulberg, D., Fierro, A., Floege, J., Frese, S., Guillevin, L., Holdsworth, S., Hughes, J., Kettritz, R., Kluger, M., Krebs, C., Lapteva, L., Levin, A., Li, J., Lightstone, L., Mack, M., Mansouri, L., McAdoo, S., McKinney, E., Panzer, U., Parikh, S., Pusey, C., Putterman, C., Rabelink, T., Radbruch, A., Rees, A., Reilly, M., Reinders, M., Remuzzi, G., Ruggenenti, P., Sacks, S., Schall, T.J., Meyer-Schwesinger, C., Sharma, K., Suzuki, Y., Tomas, N.M. and Zhao, M.H.
Kidney International Reports 1 (4): 327-339. November 2016

Early pregnancy angiogenic markers and spontaneous abortion: an Odense Child Cohort study.
Andersen, L.B., Dechend, R., Karumanchi, S.A., Nielsen, J., Joergensen, J.S., Jensen, T.K. and Christesen, H.T.
American Journal of Obstetrics and Gynecology 215 (5): 594.e1-594.e11. November 2016

Prediction of preeclampsia with angiogenic biomarkers. Results from the prospective Odense Child Cohort.
Andersen, L.B., Dechend, R., Jørgensen, J.S., Luef, B.M., Nielsen, J., Barington, T. and Christesen, H.T.
Hypertension in Pregnancy 35 (3): 405-419. August 2016

Vitamin D depletion does not affect key aspects of the preeclamptic phenotype in a transgenic rodent model for preeclampsia.
Andersen, L.B., Golic, M., Przybyl, L., Sorensen, G.L., Jørgensen, J.S., Fruekilde, P., von Versen-Höynck, F., Herse, F., Højskov, C.S., Dechend, R., Christesen, H.T. and Haase, N.
Journal of the American Society of Hypertension 10 (7): 597-607.e1. July 2016

The association between angiogenic markers and fetal sex: implications for preeclampsia research.
Andersen, L.B., Jørgensen, J.S., Herse, F., Andersen, M.S., Christesen, H.T. and Dechend, R.
Journal of Reproductive Immunology 117 : 24-29. September 2016

Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease.
Andersen, O.M., Rudolph, I.M. and Willnow, T.E.
Acta Neuropathologica 132 (5): 653-665. November 2016

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
Andlauer, T.F.M., Buck, D., Antony, G., Bayas, A., Bechmann, L., Berthele, A., Chan, A., Gasperi, C., Gold, R., Graetz, C., Haas, J., Hecker, M., Infante-Duarte, C., Knop, M., Kümpfel, T., Limmroth, V., Linker, R.A., Loleit, V., Luessi, F., Meuth, S.G., Muehlau, M., Nischwitz, S., Paul, F., Pütz, M., Ruck, T., Salmen, A., Stangel, M., Stellmann, J.P., Stuerner, K.H., Tackenberg, B., Then Bergh, F., Tumani, H., Warnke, C., Weber, F., Wiendl, H., Wildemann, B., Zettl, U.K., Ziemann, U., Zipp, F., Arloth, J., Weber, P., Radivojkov-Blagojevic, M., Scheinhardt, M.O., Dankowski, T., Bettecken, T., Lichtner, P., Czamara, D., Carrillo-Roa, T., Binder, E.B., Berger, K., Bertram, L., Franke, A., Gieger, C., Herms, S., Homuth, G., Ising, M., Jöckel, K.H., Kacprowski, T., Kloiber, S., Laudes, M., Lieb, W., Lill, C.M., Lucae, S., Meitinger, T., Moebus, S., Mueller-Nurasyid, M., Nöthen, M.M., Petersmann, A., Rawal, R., Schminke, U., Strauch, K., Völzke, H., Waldenberger, M., Wellmann, J., Porcu, E., Mulas, A., Pitzalis, M., Sidore, C., Zara, I., Cucca, F., Zoledziewska, M., Ziegler, A., Hemmer, B. and Müller-Myhsok, B.
Science Advances 2 (6): e1501678. 17 June 2016

destiny: diffusion maps for large-scale single-cell data in R.
Angerer, P., Haghverdi, L., Büttner, M., Theis, F.J., Marr, C. and Buettner, F.
Bioinformatics 32 (8): 1241-1243. 15 April 2016

Membrane fission by dynamin: what we know and what we need to know.
Antonny, B., Burd, C., De Camilli, P., Chen, E., Daumke, O., Faelber, K., Ford, M., Frolov, V.A., Frost, A., Hinshaw, J.E., Kirchhausen, T., Kozlov, M.M., Lenz, M., Low, H.H., McMahon, H., Merrifield, C., Pollard, T.D., Robinson, P.J., Roux, A. and Schmid, S.
EMBO Journal 35 (21): 2270-2284. 2 November 2016

Coelomic epithelium-derived cells in visceral morphogenesis.
Ariza, L., Carmona, R., Canete, A., Cano, E. and Munoz-Chapuli, R.
Developmental Dynamics 245 (3): 307-322. March 2016

Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo.
Arreba-Tutusaus, P., Mack, T.S., Bullinger, L., Schnöder, T.M., Polanetzki, A., Weinert, S., Ballaschk, A., Wang, Z., Deshpande, A.J., Armstrong, S.A., Döhner, K., Fischer, T. and Heidel, F.H.
Leukemia 30 (5): 1220-1225. May 2016

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers.
Arumughan, A., Roske, Y., Barth, C., Lleras Forero, L., Bravo-Rodriguez, K., Redel, Al., Kostova, S., McShane, E., Opitz, R., Faelber, K., Rau, K., Mielke, T., Daumke, O., Selbach, M., Sanchez-Garcia, E., Rocks, O., Panáková, D., Heinemann, U. and Wanker, E.E.
Nature Communications 7 : 13047. 20 October 2016

Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk.
Ashktorab, H., Hermann, P., Nouraie, M., Shokrani, B., Lee, E., Haidary, T., Brim, H. and Stein, U.
Journal of Translational Medicine 14 (1): 215. 20 July 2016

Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study.
Ayzenberg, I., Schöllhammer, J., Hoepner, R., Hellwig, K., Ringelstein, M., Aktas, O., Kümpfel, T., Krumbholz, M., Trebst, C., Paul, F., Pache, F., Obermann, M., Zeltner, L., Schwab, M., Berthele, A., Jarius, S. and Kleiter, I.
Journal of Neurology 263 (3): 575-582. March 2016

Glioma stem cells but not bulk glioma cells upregulate IL-6 secretion in microglia/brain macrophages via toll-like receptor 4 signaling.
a Dzaye, O.D., Hu, F., Derkow, K., Haage, V., Euskirchen, P., Harms, C., Lehnardt, S., Synowitz, M., Wolf, S.A. and Kettenmann, H.
Journal of Neuropathology and Experimental Neurology 75 (5): 429-440. 1 May 2016

B

Associations of anthropometric markers with serum metabolites using a targeted metabolomics approach: results of the EPIC-potsdam study.
Bachlechner, U., Floegel, A., Steffen, A., Prehn, C., Adamski, J., Pischon, T. and Boeing, H.
Nutrition & Diabetes 6 : e215. 27 June 2016

Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same.
Max-Delbrück-Centrum für Molekulare Medizin.
WO/2016/135199. 1 September 2016

Inhibition of DNA-topoisomerase I by acylated triterpene saponins from pittosporum angustifolium Lodd.
Baecker, C., Drwal, M.N., Preissner, R. and Lindequist, U.
Natural Products and Bioprospecting 6 (2): 141-147. April 2016

Computational methods for prediction of in vitro effects of new chemical structures.
Banerjee, P., Siramshetty, V.B., Drwal, M.N. and Preissner, R.
Journal of Cheminformatics 8 (1): 51. 29 September 2016

Dynamics of the ligand binding domain layer during AMPA receptor activation.
Baranovic, J., Chebli, M., Salazar, H., Carbone, A.L., Faelber, K., Lau, A.Y., Daumke, O. and Plested, A.J.R.
Biophysical Journal 110 (4): 896-911. 23 February 2016

OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation.
Barrera, M., Koob, S., Dikov, D., Vogel, F. and Reichert, A.S.
FEBS Letters 590 (19): 3309-3322. October 2016

Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration.
Barrionuevo, F.J., Hurtado, A., Kim, G.J., Real, F.M., Bakkali, M., Kopp, J.L., Sander, M., Scherer, G., Burgos, M. and Jiménez, R.
eLife 5 : e15635. 21 June 2016

Three-layered proteomic characterization of a novel ACTN4 mutation unravels its pathogenic potential in FSGS.
Bartram, M.P., Habbig, S., Pahmeyer, C., Höhne, M., Weber, L.T., Thiele, H., Altmüller, J., Kottoor, N., Wenzel, A., Krueger, M., Schermer, B., Benzing, T., Rinschen, M.M. and Beck, B.B.
Human Molecular Genetics 25 (6): 1152-1164. 15 March 2016

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.
Bartus, K., Galino, J., James, N.D., Hernandez-Miranda, L.R., Dawes, J.M., Fricker, F.R., Garratt, A.N., McMahon, S.B., Ramer, M.S., Birchmeier, C., Bennett, D.L.H. and Bradbury, E.J.
Brain 139 (Pt 5): 1394-1416. May 2016

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function.
Batalha, V.L., Ferreira, D.G., Coelho, J.E., Valadas, J.S., Gomes, R., Temido-Ferreira, M., Shmidt, T., Baqi, Y., Buée, L., Müller, C.E., Hamdane, M., Outeiro, T.F., Bader, M., Meijsing, S.H., Sadri-Vakili, G., Blum, D. and Lopes, L.V.
Scientific Reports 6 : 31493. 11 August 2016

Feedback, mass conservation and reaction kinetics impact the robustness of cellular oscillations.
Baum, K., Politi, A.Z., Kofahl, B., Steuer, R. and Wolf, J.
PLoS Computational Biology 12 (12): e1005298. 27 December 2016

Maximizing information from routine staging computed tomography in functional neuroendocrine neoplasms: are there findings indicating the presence of carcinoid heart disease?
Baur, A.D.J., Kunz, F., Schwenke, C., Pschowski, R., Roepke, T.K., Pavel, M. and Denecke, T.
Journal of Computer Assisted Tomography 40 (2): 277-282. March 2016

Examining topological domain influence on enhancer function.
Beagrie, R.A. and Pombo, A.
Developmental Cell 39 (5): 523-524. 5 December 2016

Gene activation by metazoan enhancers: diverse mechanisms stimulate distinct steps of transcription.
Beagrie, R.A. and Pombo, A.
BioEssays 38 (9): 881-893. September 2016

Proteomic techniques to probe the ubiquitin landscape.
Beaudette, P., Popp, O. and Dittmar, G.
Proteomics 16 (2): 273-287. January 2016

Uwe Heinemann (17.2.1944-8.9.2016).
Beck, H., Draguhn, A., Luhmann, H. and Schmitz, D.
Neuroforum 22 (4): 137-138. December 2016

Poly(ADP-ribosyl)ation of Methyl CpG binding domain protein 2 regulates chromatin structure.
Becker, A., Zhang, P., Allmann, L., Meilinger, D., Bertulat, B., Eck, D., Hofstaetter, M., Bartolomei, G., Hottiger, M.O., Schreiber, V., Leonhardt, H. and Cardoso, M.C.
Journal of Biological Chemistry 291 (10): 4873-4881. 4 March 2016

The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration.
Becker, M.S., Müller, P.M., Bajorat, J., Schroeder, A., Giaisi, M., Amin, E., Ahmadian, M.R., Rocks, O., Köhler, R., Krammer, P.H. and Li-Weber, M.
Oncotarget 7 (32): 51908-51921. 9 August 2016

Metabolomics enables precision medicine: "A White Paper, Community Perspective".
Beger, R.D., Dunn, W., Schmidt, M.A., Gross, S.S., Kirwan, J.A., Cascante, M., Brennan, L., Wishart, D.S., Oresic, M., Hankemeier, T., Broadhurst, D.I., Lane, A.N., Suhre, K., Kastenmüller, G., Sumner, S.J., Thiele, I., Fiehn, O. and Kaddurah-Daouk, R.
Metabolomics 12 (9): 149. September 2016

Low 25-hydroxyvitamin D, but not the bioavailable fraction of 25-hydroxyvitamin D, is a risk factor for multiple sclerosis.
Behrens, J.R., Rasche, L., Giess, R.M., Pfuhl, C., Wakonig, K., Freitag, E., Deuschle, K., Bellmann-Strobl, J., Paul, F., Ruprecht, K. and Doerr, J.
European Journal of Neurology 23 (1): 62-67. January 2016

Validity of visual perceptive computing for static posturography in patients with multiple sclerosis.
Behrens, J.R., Mertens, S., Krüger, T., Grobelny, A., Otte, K., Mansow-Model, S., Gusho, E., Paul, F., Brandt, A.U. and Schmitz-Hübsch, T.
Multiple Sclerosis Journal 22 (12): 1596-1606. October 2016

Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles.
Bel Abed, H., Schoene, J., Christmann, M. and Nazare, M.
Organic & Biomolecular Chemistry 14 (36): 8520-8528. 28 September 2016

Human genetics of ventricular septal defect.
Bellmann, K., Perrot, A. and Rickert-Sperling, S.
In: Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways. Springer, Vienna, 307-328. ISBN 978-3-7091-1882-5 2016

A c-Myc/miR17-92/Pten axis controls PI3K-mediated positive and negative selection in B cell development and reconstitutes CD19 deficiency.
Benhamou, D., Labi, V., Novak, R., Dai, I., Shafir-Alon, S., Weiss, A., Gaujoux, R., Arnold, R., Shen-Orr, S.S., Rajewsky, K. and Melamed, D.
Cell Reports 16 (2): 419-431. 12 July 2016

Advances in β cell replacement and regeneration strategies for treating diabetes.
Benthuysen, J.R., Carrano, A.C. and Sander, M.
Journal of Clinical Investigation 126 (10): 3651-3660. 3 October 2016

A mutation in the glutamate-rich region of RBM20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism.
Beqqali, A., Bollen, I.A.E., Rasmussen, T.B., van den Hoogenhof, M.M., van Deutekom, H.W.M., Schafer, S., Haas, J., Meder, B., Sorensen, K.E., van Oort, R.J., Mogensen, J., Hubner, N., Creemers, E.E., van der Velden, J. and Pinto, Y.M.
Cardiovascular Research 112 (1): 452-463. 1 October 2016

Isolation of eosinophils from the lamina propria of the murine small intestine.
Berek, C., Beller, A. and Chu, V.T.
Methods in Molecular Biology 1422 : 213-221. 2016

Multiple myeloma cells modify VEGF/IL-6 levels and osteogenic potential of bone marrow stromal cells via Notch/miR-223.
Berenstein, R., Nogai, A., Waechter, M., Blau, O., Kuehnel, A., Schmidt-Hieber, M., Kunitz, A., Pezzutto, A., Dörken, B. and Blau, I.W.
Molecular Carcinogenesis 55 (12): 1927-1939. December 2016

A germline chromothripsis event stably segregating in 11 individuals through three generations.
Bertelsen, B., Nazaryan-Petersen, L., Sun, W., Mehrjouy, M.M., Xie, G., Chen, W., Hjermind, L.E., Taschner, P.E.M. and Tuemer, Z.
Genetics in Medicine 18 (5): 494-500. May 2016

Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune, M.T., Gee, M.H., Bunse, M., Lee, M.S., Gschweng, E.H., Pagadala, M.S., Zhou, J., Cheng, D., Heath, J.R., Kohn, D.B., Kuhns, M.S., Uckert, W. and Baltimore, D.
eLife 5 : e19095. 8 November 2016

Replication of the association between CHRNA4 rs1044396 and harm avoidance in a large population-based sample.
Bey, K., Lennertz, L., Markett, S., Petrovsky, N., Gallinat, J., Gruender, G., Spreckelmeyer, K.N., Wienker, T.F., Mobascher, A., Dahmen, N., Thuerauf, N., Kornhuber, J., Kiefer, F., Toliat, M.R., Nuernberg, P., Winterer, G. and Wagner, M.
European Neuropsychopharmacology 26 (1): 150-155. January 2016

The immunoproteasomes are key to regulate myokines and MHC class I expression in idiopathic inflammatory myopathies.
Bhattarai, S., Ghannam, K., Krause, S., Benveniste, O., Marg, A., de Bruin, G., Xin, B.T., Overkleeft, H.S., Spuler, S., Stenzel, W. and Feist, E.
Journal of Autoimmunity 75 : 118-129. December 2016

Proteomics quality control : a quality control software for MaxQuant results.
Bielow, C., Mastrobuoni, G. and Kempa, S.
Journal of Proteome Research 15 (3): 777-787. 4 March 2016

Orchestrating Wnt signalling for metabolic liver zonation.
Birchmeier, W.
Nature Cell Biology 18 (5): 463-465. May 2016

Neuregulin/ErbB signaling in developmental myelin formation and nerve repair.
Birchmeier, C. and Bennett, D.L.H.
Current Topics in Developmental Biology 116 : 45-64. 2016

Ultra-Long-term human salt balance studies reveal interrelations between sodium, potassium, and chloride intake and excretion.
Birukov, A., Rakova, N., Lerchl, K., Olde Engberink, R.H.G., Johannes, B., Wabel, P., Moissl, U., Rauh, M., Luft, F.C. and Titze, J.
American Journal of Clinical Nutrition 104 (1): 49-57. July 2016

Angiotensin II type 1 receptor antibodies in childhood kidney transplantation.
Bjerre, A., Tangeraas, T., Heidecke, H., Dragun, D., Dechend, R. and Staff, A.C.
Pediatric Transplantation 20 (5): 627-632. August 2016

Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI.
Blaabjerg, M., Ruprecht, K., Sinnecker, T., Kondziella, D., Niendorf, T., Kerrn-Jespersen, B.M., Lindelof, M., Lassmann, H., Kristensen, B.W., Paul, F. and Illes, Z.
Neurology Neuroimmunology & Neuroinflammation 3 (3): e226. June 2016

Receptor combinations hone T-cell therapy.
Blankenstein, T.
Nature Biotechnology 34 (4): 389-391. 7 April 2016

Systematic errors in peptide and protein identification and quantification by modified peptides.
Bogdanow, B., Zauber, H. and Selbach, M.
Molecular & Cellular Proteomics 15 (8): 2791-2801. 1 August 2016

Strong impact of extramedullary involvement in high-risk AML patients with active disease receiving the FLAMSA conditioning regimen for HSCT.
Bohl, S., von Harsdorf, S., Mulaw, M., Hofmann, S., Babiak, A., Maier, C.P., Schnell, J., Hütter-Krönke, L.M., Scholl, K., Wais, V., Schlenk, R.F., Bullinger, L., Ringhoffer, M., Döhner, H., Bunjes, D., Bommer, M. and Kuchenbauer, F.
Bone Marrow Transplantation 51 (7): 994-996. July 2016

Vasopressin lowers renal epoxyeicosatrienoic acid levels by activating soluble epoxide hydrolase.
Boldt, C., Roeschel, T., Himmerkus, N., Plain, A., Bleich, M., Labes, R., Blum, M., Krause, H., Magheli, A., Giesecke, T., Mutig, K., Rothe, M., Weldon, S.M., Dragun, D., Schunck, W.H., Bachmann, S. and Paliege, A.
American Journal of Physiology Renal Physiology 311 (6): F1198-F1210. 1 December 2016

Calcineurin and sorting-related receptor with A-type repeats interact to regulate the renal Na(+)-K(+)-2Cl(-) cotransporter.
Borschewski, A., Himmerkus, N., Boldt, C., Blankenstein, K.I., McCormick, J.A., Lazelle, R., Willnow, T.E., Jankowski, V., Plain, A., Bleich, M., Ellison, D.H., Bachmann, S. and Mutig, K.
Journal of the American Society of Nephrology 27 (1): 107-119. January 2016

ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss.
Brachs, M., Wiegand, S., Leupelt, V., Ernert, A., Kintscher, U., Jumpertz von Schwarzenberg, R., Decker, A.M., Bobbert, T., Hübner, N., Chen, W., Krude, H., Spranger, J. and Mai, K.
Metabolism 65 (6): 935-943. June 2016

Axial tubule junctions control rapid calcium signaling in atria.
Brandenburg, S., Kohl, T., Williams, G.S.B., Gusev, K., Wagner, E., Rog-Zielinska, E.A., Hebisch, E., Dura, M., Didié, M., Gotthardt, M., Nikolaev, V.O., Hasenfuss, G., Kohl, P., Ward, C.W., Lederer, W.J. and Lehnart, S.E.
Journal of Clinical Investigation 126 (10): 3999-4015. 3 October 2016

Retinal lesion evolution in susac syndrome.
Brandt, A.U., Oberwahrenbrock, T., Costello, F., Fielden, M., Gertz, K., Kleffner, I., Paul, F., Bergholz, R. and Doerr, J.
Retina 36 (2): 366-374. February 2016

Afferent visual pathway affection in patients with PMP22 deletion-related hereditary neuropathy with liability to pressure palsies.
Brandt, A.U., Meinert-Bohn, E., Rinnenthal, J., Zimmermann, H., Mikolajczak, J., Oberwahrenbrock, T., Papazoglou, S., Pfüller, C.F., Schinzel, J., Tackenberg, B., Paul, F., Hahn, K. and Bellmann-Strobl, J.
PLoS ONE 11 (10): e0164617. 17 October 2016

Visual dysfunction, but not retinal thinning, following anti-NMDA receptor encephalitis.
Brandt, A.U., Oberwahrenbrock, T., Mikolajczak, J., Zimmermann, H., Prüss, H., Paul, F. and Finke, C.
Neurology Neuroimmunology & Neuroinflammation 3 (2): e198. April 2016

Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination.
Braten, O., Livneh, I., Ziv, T., Admon, A., Kehat, I., Caspi, L.H., Gonen, H., Bercovich, B., Godzik, A., Jahandideh, S., Jaroszewski, L., Sommer, T., Kwon, Y.T., Guharoy, M., Tompa, P. and Ciechanover, A.
Proceedings of the National Academy of Sciences of the United States of America 113 (32): E4639-E4647. 9 August 2016

Longitudinal intravital imaging of the retina reveals long-term dynamics of immune infiltration and its effects on the glial network in experimental autoimmune uveoretinitis, without evident signs of neuronal dysfunction in the ganglion cell layer.
Bremer, D., Pache, F., Guenther, R., Hornow, J., Andresen, V., Leben, R., Mothes, R., Zimmermann, H., Brandt, A.U., Paul, F., Hauser, A.E., Radbruch, H. and Niesner, R.
Frontiers in Immunology 7 : 642. 23 December 2016

Current approaches toward quantitative mapping of the interactome.
Buntru, A., Trepte, P., Klockmeier, K., Schnoegl, S. and Wanker, E.E.
Frontiers in Genetics 7 : 74. 4 May 2016

Modeling cardiovascular diseases with patient-specific human pluripotent stem cell-derived cardiomyocytes.
Burridge, P.W., Diecke, S., Matsa, E., Sharma, A., Wu, H. and Wu, J.C.
Methods in Molecular Biology 1353 : 119-130. 2016

Adaptation of external counterpulsation based on individual shear rate therapy improves endothelial function and claudication distance in peripheral artery disease.
Buschmann, E.E., Brix, M., Li, L., Doreen, J., Zietzer, A., Li, M., Buschmann, I. and Hillmeister, P.
Vasa - Zeitschrift fuer Gefaesskrankheiten 45 (4): 317-324. 18 July 2016

C-type natriuretic peptide and NPR-B signalling inhibits cardiac sympathetic neurotransmission and autonomic function.
Buttgereit, J., Shanks, J., Li, D., Hao, G., Athwal, A., Langenickel, T.H., Wright, H., da Costa Goncalves, A.C., Monti, J., Plehm, R., Popova, E., Qadri, F., Lapidus, I., Ryan, B., Özcelik, C., Paterson, D.J., Bader, M. and Herring, N.
Cardiovascular Research 112 (3): 637-644. December 2016

C

Identification of parvalbumin interneurons as cellular substrate of fear memory persistence.
Caliskan, G., Mueller, I., Semtner, M., Winkelmann, A., Raza, A.S., Hollnagel, J.O., Roesler, A., Heinemann, U., Stork, O. and Meier, J.C.
Cerebral Cortex 26 (5): 2325-2340. May 2016

Detecting actively translated open reading frames in ribosome profiling data.
Calviello, L., Mukherjee, N., Wyler, E., Zauber, H., Hirsekorn, A., Selbach, M., Landthaler, M., Obermayer, B. and Ohler, U.
Nature Methods 13 (2): 165-170. February 2016

On fine stochastic simulations of liposome-encapsulated PUREsystem(TM).
Calviello, L., Lazzerini-Ospri, L. and Marangoni, R.
In: 10th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2015, 22-25 Sept 2015, Bari, Italy. 2016

Sortilin regulates sorting and secretion of Sonic hedgehog.
Campbell, C., Beug, S., Nickerson, P.E.B., Peng, J., Mazerolle, C., Bassett, E., Ringuette, R., Jama, F.A., Morales, C., Christ, A. and Wallace, V.A.
Journal of Cell Science 129 (20): 3832-3844. 15 October 2016

Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections.
Cano, E., Carmona, R., Ruiz-Villalba, A., Rojas, A., Chau, Y.Y., Wagner, K.D., Wagner, N., Hastie, N.D., Munoz-Chapuli, R. and Perez-Pomares, J.M.
Proceedings of the National Academy of Sciences of the United States of America 113 (3): 656-661. 19 January 2016

Acute effects of ferumoxytol on regulation of renal hemodynamics and oxygenation.
Cantow, K., Pohlmann, A., Flemming, B., Ferrara, F., Waiczies, S., Grosenick, D., Niendorf, T. and Seeliger, E.
Scientific Reports 6 : 29965. 20 July 2016

A medical device-grade T1 and ECV phantom for global T1 mapping quality assurance - the T1 Mapping and ECV Standardization in cardiovascular magnetic resonance (T1MES) program.
Captur, G., Gatehouse, P., Keenan, K.E., Heslinga, F.G., Bruehl, R., Prothmann, M., Graves, M.J., Eames, R.J., Torlasco, C., Benedetti, G., Donovan, J., Ittermann, B., Boubertakh, R., Bathgate, A., Royet, C., Pang, W., Nezafat, Reza, Salerno, M., Kellman, P. and Moon, J.C.
Journal of Cardiovascular Magnetic Resonance 18 (1): 58. 22 September 2016

Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice.
Carmona, R., Canete, A., Cano, E., Ariza, L., Rojas, A. and Munoz-Chapuli, R.
eLife 5 : e16009. 19 September 2016

A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.
Casado-Medrano, V., Barrio-Real, L., García-Rostán, G., Baumann, M., Rocks, O. and Caloca, M.J.
Oncotarget 7 (19): 28301-28319. 10 May 2016

4D visualization of replication foci in mammalian cells corresponding to individual replicons.
Chagin, V.O., Casas-Delucchi, C.S., Reinhart, M., Schermelleh, L., Markaki, Y., Maiser, A., Bolius, J.J., Bensimon, A., Fillies, M., Domaing, P., Rozanov, Y.M., Leonhardt, H. and Cardoso, M.C.
Nature Communications 7 : 11231. 7 April 2016

Welcome to Biomedicine Hub.
Chan, J.Y.H., Chan, S.H.H., Cosci, F., Gardiner, D.M., Gollasch, M., Gwinn, M., Isgaard, J., Kalantar-Zadeh, K., Patrinos, G.P., Rubinstein, I., Schmid, M., Sherman, M., Simon, H.U., Stratakis, C.A., Tanner, M. and Zaenker, K.S.
Biomedicine Hub 1 (1): 1-2. 2016

Insufficient treatment of severe depression in neuromyelitis optica spectrum disorder.
Chavarro, V.S., Mealy, M.A., Simpson, A., Lacheta, A., Pache, F., Ruprecht, K., Gold, S.M., Paul, F., Brandt, A.U. and Levy, M.
Neurology Neuroimmunology & Neuroinflammation 3 (6): e286. December 2016

Iron and non-iron-related characteristics of multiple sclerosis and neuromyelitis optica lesions at 7T MRI.
Chawla, S., Kister, I., Wuerfel, J., Brisset, J.C., Liu, S., Sinnecker, T., Dusek, P., Haacke, E.M., Paul, F. and Ge, Y.
American Journal of Neuroradiology 37 (7): 1223-1230. July 2016

Eyes on translation.
Chekulaeva, M. and Landthaler, M.
Molecular Cell 63 (6): 918-925. 15 September 2016

Energy efficiency trade-offs drive nucleotide usage in transcribed regions.
Chen, W.H., Lu, G., Bork, P., Hu, S. and Lercher, M.J.
Nature Communications 7 : 11334. 21 April 2016

Integration of multi-omics data of a genome-reduced bacterium: prevalence of post-transcriptional regulation and its correlation with protein abundances.
Chen, W.H., van Noort, V., Lluch-Senar, M., Hennrich, M.L., Wodke, J.A.H., Yus, E., Alibes, A., Roma, G., Mende, D.R., Pesavento, C., Typas, A., Gavin, A.C., Serrano, L. and Bork, P.
Nucleic Acids Research 44 (3): 1192-1202. 18 February 2016

In vivo interaction proteomics in Caenorhabditis elegans embryos provides new insights into P granule dynamics.
Chen, J.X., Cipriani, P.G., Mecenas, D., Polanowska, J., Piano, F., Gunsalus, K.C. and Selbach, M.
Molecular & Cellular Proteomics 15 (5): 1642-1657. 1 May 2016

Circular RNAs in brain and other tissues: a functional enigma.
Chen, W. and Schuman, E.
Trends in Neurosciences 39 (9): 597-604. September 2016

Differential dynamics of the mammalian mRNA and protein expression response to misfolding stress.
Cheng, Z., Teo, G., Krueger, S., Rock, T.M., Koh, H.W.L., Choi, H. and Vogel, C.
Molecular Systems Biology 12 (1): 855. 20 January 2016

Striatal adenosine-cannabinoid receptor interactions in rats overexpressing adenosine A2A receptors.
Chiodi, V., Ferrante, A., Ferraro, L., Potenza, R.L., Armida, M., Beggiato, S., Pezzola, A., Bader, M., Fuxe, K., Popoli, P. and Domenici, M.R.
Journal of Neurochemistry 136 (5): 907-917. March 2016

miR-23~27~24 clusters control effector T cell differentiation and function.
Cho, S., Wu, C.J., Yasuda, T., Cruz, L.O., Khan, A.A., Lin, L.L., Nguyen, D.T., Miller, M., Lee, H.M., Kuo, M.L., Broide, D.H., Rajewsky, K., Rudensky, A.Y. and Lu, L.F.
Journal of Experimental Medicine 213 (2): 235-249. 8 February 2016

A diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms.
Choi, I.Y., Piccio, L., Childress, P., Bollman, B., Ghosh, A., Brandhorst, S., Suarez, J., Michalsen, A., Cross, A.H., Morgan, T.E., Wei, M., Paul, F., Bock, M. and Longo, V.D.
Cell Reports 15 (10): 2136-2146. 7 June 2016

T cell PTLD successfully treated with single-agent brentuximab vedotin first-line therapy.
Choi, M., Fink, S., Prasad, V., Anagnostopoulos, I., Reinke, P. and Schmitt, C.A.
Transplantation 100 (3): e8-e10. March 2016

Karyopherin alpha 1 regulates satellite cell proliferation and survival by modulating nuclear import.
Choo, H.J., Cutler, A., Rother, F., Bader, M. and Pavlath, G.K.
Stem Cells 34 (11): 2784-2797. November 2016

LRP2, an auxiliary receptor that controls sonic hedgehog signaling in development and disease.
Christ, A., Herzog, K. and Willnow, T.E.
Developmental Dynamics 245 (5): 569-579. May 2016

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Chu, V.T., Graf, R., Wirtz, T., Weber, T., Favret, J., Li, X., Petsch, K., Tran, N.T., Sieweke, M.H., Berek, C., Kühn, R. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (44): 12514-12519. 1 November 2016

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Chu, V.T., Weber, T., Graf, R., Sommermann, T., Petsch, K., Sack, U., Volchkov, P., Rajewsky, K. and Kühn, R.
BMC Biotechnology 16 (1): 4. 16 January 2016

Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study.
Chuang, S.C., Boeing, H., Vollset, S.E., Midttun, Ø., Ueland, P.M., Bueno-de-Mesquita, B., Lajous, M., Fagherazzi, G., Boutron-Ruault, M.C., Kaaks, R., Kühn, T., Pischon, T., Drogan, D., Tjønneland, A., Overvad, K., Quirós, J.R., Agudo, A., Molina-Montes, E., Dorronsoro, M., Huerta, J.M., Barricarte, A., Khaw, K.T., Wareham, N.J., Travis, R.C., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Masala, G., Agnoli, C., Tumino, R., Mattiello, A., Peeters, P.H., Weiderpass, E., Palmqvist, R., Ljuslinder, I., Gunter, M., Lu, Y., Cross, A.J., Riboli, E., Vineis, P. and Aleksandrova, K.
Immunity & Ageing 13 : 5. 25 February 2016

Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers.
Claes, G.R.F., van Tienen, F.H.J., Lindsey, P., Krapels, I.P.C., Helderman-van den Enden, A.T.J.M., Hoos, M.B., Barrois, Y.E.G., Janssen, J.W.H., Paulussen, A.D.C., Sels, J.W.E.M., Kuijpers, S.H.H., van Tintelen, J.P., van den Berg, M.P., Heesen, W.F., Garcia-Pavia, P., Perrot, A., Christiaans, I., Salemink, S., Marcelis, C.L.M., Smeets, H.J.M., Brunner, H.G., Volders, P.G.A. and van den Wijngaard, A.
European Heart Journal 37 (23): 1815-1822. 14 June 2016

Autophagy in T and B lymphocytes.
Clarke, A.J. and Simon, A.K.
Autophagy Networks in Inflammation : 171-184. 25 August 2016

Low-grade glioma surgery in intraoperative magnetic resonance imaging: Results of a multicenter retrospective assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging.
Coburger, J., Merkel, A., Scherer, M., Schwartz, F., Gessler, F., Roder, C., Pala, A., König, R., Bullinger, L., Nagel, G., Jungk, C., Bisdas, S., Nabavi, A., Ganslandt, O., Seifert, V., Tatagiba, M., Senft, C., Mehdorn, M., Unterberg, A.W., Rössler, K. and Wirtz, C.R.
Neurosurgery 78 (6): 775-86. June 2016

miRNAs are essential for the regulation of the PI3K/AKT/FOXO pathway and receptor editing during B cell maturation.
Coffre, M., Benhamou, D., Riess, D., Blumenberg, L., Snetkova, V., Hines, M.J., Chakraborty, T., Bajwa, S., Jensen, K., Chong, M.M.W., Getu, L., Silverman, G.J., Blelloch, R., Littman, D.R., Calado, D., Melamed, D., Skok, J.A., Rajewsky, K. and Koralov, S.B.
Cell Reports 17 (9): 2271-2285. 22 November 2016

Using concept mapping in the development of the EU-PAD framework (EUropean-Physical Activity Determinants across the life course): a DEDIPAC-study.
Condello, G., Ling, F.C.M., Bianco, A., Chastin, S., Cardon, G., Ciarapica, D., Conte, D., Cortis, C., De Craemer, M., Di Blasio, A., Gjaka, M., Hansen, S., Holdsworth, M., Iacoviello, L., Izzicupo, P., Jaeschke, L., Leone, L., Manoni, L., Menescardi, C., Migliaccio, S., Nazare, J.A., Perchoux, C., Pesce, C., Pierik, F., Pischon, T., Polito, A., Puggina, A., Sannella, A., Schlicht, W., Schulz, H., Simon, C., Steinbrecher, A., MacDonncha, C. and Capranica, L.
BMC Public Health 16 (1): 1145. 9 November 2016

Serial interactome capture of the human cell nucleus.
Conrad, T., Albrecht, A.-S., Rodrigues de Melo Costa, V., Sauer, S., Meierhofer, D. and Ørom, U.A.
Nature Communications 7 : 11212. 4 April 2016

Tracking transient conformational states of T4 lysozyme at room temperature combining X-ray crystallography and site-directed spin labeling.
Consentius, P., Gohlke, U., Loll, B., Alings, C., Mueller, R., Heinemann, U., Kaupp, M., Wahl, M. and Risse, T.
Journal of the American Chemical Society 138 (39): 12868-12875. 5 October 2016

Cyanobacterial symbionts diverged in the late Cretaceous towards lineage-specific nitrogen fixation factories in single-celled phytoplankton.
Cornejo-Castillo, F.M., Cabello, A.M., Salazar, G., Sanchez-Baracaldo, P., Lima-Mendez, G., Hingamp, P., Alberti, A., Sunagawa, S., Bork, P., de Vargas, C., Raes, J., Bowler, C., Wincker, P., Zehr, J.P., Gasol, J.M., Massana, R. and Acinas, S.G.
Nature Communications 7 : 11071. 22 March 2016

Reduced uterine perfusion pressure T-helper 17 cells cause pathophysiology associated with preeclampsia during pregnancy.
Cornelius, D.C., Amaral, L.M., Wallace, K., Campbell, N., Thomas, A.J., Scott, J., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 311 (6): R1192-R1199. 1 December 2016

Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Coscia, F., Watters, K.M., Curtis, M., Eckert, M.A., Chiang, C.Y., Tyanova, S., Montag, A., Lastra, R.R., Lengyel, E. and Mann, M.
Nature Communications 7 : 12645. 26 August 2016

Asymmetric division coordinates collective cell migration in angiogenesis.
Costa, G., Harrington, K.I., Lovegrove, H.E., Page, D.J., Chakravartula, S., Bentley, K. and Herbert, S.P.
Nature Cell Biology 18 (12): 1292-1301. December 2016

Placebo-controlled study in neuromyelitis optica : ethical and design considerations.
Cree, B.A.C., Bennett, J.L., Sheehan, M., Cohen, J., Hartung, H.P., Aktas, O., Kim, H.J., Paul, F., Pittock, S., Weinshenker, B., Wingerchuk, D., Fujihara, K., Cutter, G., Patra, K., Flor, A., Barron, G., Madani, S., Ratchford, J.N. and Katz, E.
Multiple Sclerosis Journal 22 (7): 862-872. June 2016

Genome-wide polyadenylation maps reveal dynamic mRNA 3'-end formation in the failing human heart.
Creemers, E.E., Bawazeer, A., Ugalde, A.P., van Deutekom, H.W.M., van der Made, I., de Groot, N.E., Adriaens, M.E., Cook, S.A., Bezzina, C.R., Hubner, N., van der Velden, J., Elkon, R., Agami, R. and Pinto, Y.M.
Circulation Research 118 (3): 433-438. 5 February 2016

Glycolytic regulation of cell rearrangement in angiogenesis.
Cruys, B., Wong, B.W., Kuchnio, A., Verdegem, D., Cantelmo, A. R., Conradi, L.C., Vandekeere, S., Bouché, A., Cornelissen, I., Vinckier, S., Merks, R.M.H., Dejana, E., Gerhardt, H., Dewerchin, M., Bentley, K. and Carmeliet, P.
Nature Communications 7 : 12240. 20 July 2016

The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.
Cruz-Herranz, A., Balk, L.J., Oberwahrenbrock, T., Saidha, S., Martinez-Lapiscina, E.H., Lagreze, W.A., Schuman, J.S., Villoslada, P., Calabresi, P., Balcer, L., Petzold, A., Green, A.J., Paul, F., Brandt, A.U. and Albrecht, P.
Neurology 86 (24): 2303-2309. 14 June 2016

SignaFish: A zebrafish-specific signaling pathway resource.
Csalyi, K., Fazekas, D., Kadlecsik, T., Tuerei, D., Gul, L., Horvath, B., Modos, D., Demeter, A., Papai, N., Lenti, K., Csermely, P., Vellai, T., Korcsmaros, T. and Varga, M.
Zebrafish 13 (6): 541-544. 1 December 2016

Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA.
Cui, H., Schlesinger, J., Schoenhals, S., Toenjes, M., Dunkel, I., Meierhofer, D., Cano, E., Schulz, K., Berger, M.F., Haack, T., Abdelilah-Seyfried, S., Bulyk, M.L., Sauer, S. and Sperling, S.R.
Nucleic Acids Research 44 (6): 2538-2553. 7 April 2016

Comprehensive profiling of retroviral integration sites using target enrichment methods from historical koala samples without an assembled reference genome.
Cui, P., Löber, U., Alquezar-Planas, D.E., Ishida, Y., Courtiol, A., Timms, P., Johnson, R.N., Lenz, D., Helgen, K.M., Roca, A.L., Hartman, S. and Greenwood, A.D.
PeerJ 4 : e1847. 28 March 2016

Agonistic autoantibodies to the angiotensin II type 1 receptor enhance angiotensin II-induced renal vascular sensitivity and reduce renal function during pregnancy.
Cunningham, M.W., Williams, J.M., Amaral, L., Usry, N., Wallukat, G., Dechend, R. and LaMarca, B.
Hypertension 68 (5): 1308-1313. November 2016

Anchoring a leviathan: how the nuclear membrane tethers the genome.
Czapiewski, R., Robson, M.I. and Schirmer, E.C.
Frontiers in Genetics 7 : 82. 6 May 2016

The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Czimmerer, Z., Varga, T., Kiss, M., Vazquez, C.O., Doan-Xuan, Q.M., Rueckerl, D., Tattikota, S.G., Yan, X., Nagy, Z.S., Daniel, B., Poliska, S., Horvath, A., Nagy, G., Varallyay, E., Poy, M.N., Allen, J.E., Bacso, Z., Abreu-Goodger, C. and Nagy, L.
Genome Medicine 8 (1): 63. 31 May 2016

D

S100A4 in cancer metastasis: Wnt signaling-driven interventions for metastasis restriction.
Dahlmann, M., Kobelt, D., Walther, W., Mudduluru, G. and Stein, U.
Cancers 8 (6): 59. 20 June 2016

Quantitative assessment of muscle injury by (23)Na magnetic resonance imaging.
Dahlmann, A., Kopp, C., Linz, P., Cavallaro, A., Seuss, H., Eckardt, K.U., Luft, F.C., Titze, J., Uder, M. and Hammon, M.
SpringerPlus 5 (1): 661. 23 May 2016

GPR56 contributes to the development of acute myeloid leukemia in mice.
Daria, D., Kirsten, N., Muranyi, A., Mulaw, M., Ihme, S., Kechter, A., Hollnagel, M., Bullinger, L., Döhner, K., Döhner, H., Feuring-Buske, M. and Buske, C.
Leukemia 30 (8): 1734-1741. August 2016

Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily.
Daumke, O. and Praefcke, G.J.
Biopolymers 105 (8): 580-593. August 2016

Protein-mediated membrane remodeling.
Daumke, O. and Unger, V.M.
Journal of Structural Biology 196 (1): 1-2. October 2016

CART - a chemical annotation retrieval toolkit.
Deghou, S., Zeller, G., Iskar, M., Driessen, M., Castillo, M., van Noort, V. and Bork, P.
Bioinformatics 32 (18): 2869-2871. 15 September 2016

Self-organization of human embryonic stem cells on micropatterns.
Deglincerti, A., Etoc, F., Guerra, M.C., Martyn, I., Metzger, J., Ruzo, A., Simunovic, M., Yoney, A., Brivanlou, A.H., Siggia, E. and Warmflash, A.
Nature Protocols 11 (11): 2223-2232. November 2016

Random focusing of tsunami waves.
Degueldre, H., Metzger, J.J., Geisel, T. and Fleischmann, R.
Nature Physics 12 (3): 259-262. March 2016

Interleukin-7 modulates anti-tumor CD8+ T cell responses via its action on host cells.
Deiser, K., Stoycheva, D., Bank, U., Blankenstein, T. and Schüler, T.
PLoS ONE 11 (7): e0159690. 22 July 2016

The A-kinase anchoring protein (AKAP) glycogen synthase kinase 3β interaction protein (GSKIP) regulates β-catenin through its interactions with both protein kinase A (PKA) and GSK3β.
Dema, A., Schröter, M.F., Perets, E., Skroblin, P., Moutty, M.C., Deàk, V.A., Birchmeier, W. and Klussmann, E.
Journal of Biological Chemistry 291 (37): 19618-19630. 9 September 2016

Moyamoya vessel pathology imaged by ultra-high-field magnetic resonance imaging at 7.0 T.
Dengler, N.F., Madai, V.I., Wuerfel, J., von Samson-Himmelstjerna, F.C., Dusek, P., Niendorf, T., Sobesky, J. and Vajkoczy, P.
Journal of Stroke and Cerebrovascular Diseases 25 (6): 1544-1551. June 2016

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.
Derudder, E., Herzog, S., Labi, V., Yasuda, T., Köchert, K., Janz, M., Villunger, A., Schmidt-Supprian, M. and Rajewsky, K.
Proceedings of the National Academy of Sciences of the United States of America 113 (18): 5065-5070. 3 May 2016

Pharmacological interference with protein-protein interactions of A-kinase anchoring proteins as a strategy for the treatment of disease.
Deák, V.A. and Klussmann, E.
Current Drug Targets 17 (10): 1147-1171. 1 August 2016

The A-kinase anchoring protein GSKIP regulates GSK3β activity and controls palatal shelf fusion in mice.
Deák, V.A., Skroblin, P., Dittmayer, C., Knobeloch, K.P., Bachmann, S. and Klussmann, E.
Journal of Biological Chemistry 291 (2): 681-690. 8 January 2016

Update on the ACTG1-associated Baraitser–Winter cerebrofrontofacial syndrome.
Di Donato, N., Kuechler, A., Vergano, S., Heinritz, W., Bodurtha, J., Merchant, S.R., Breningstall, G., Ladda, R., Sell, S., Altmüller, J., Bögershausen, N., Timms, A.E., Hackmann, K., Schrock, E., Collins, S., Olds, C., Rump, A. and Dobyns, W.B.
American Journal of Medical Genetics Part A 170 (10): 2644-2651. October 2016

Mutations in EXOSC2 are associated with a novel syndrome characterised by retinitis pigmentosa, progressive hearing loss, premature ageing, short stature, mild intellectual disability and distinctive gestalt.
Di Donato, N., Neuhann, T., Kahlert, A.K., Klink, B., Hackmann, K., Neuhann, I., Novotna, B., Schallner, J., Krause, C., Glass, I.A., Parnell, S.E., Benet-Pages, A., Nissen, A.M., Berger, W., Altmüller, J., Thiele, H., Weber, B.H.F., Schrock, E., Dobyns, W.B., Bier, A. and Rump, A.
Journal of Medical Genetics 53 (6): 419-425. June 2016

Identification of serum metabolites associated with incident hypertension in the European Prospective Investigation into Cancer and Nutrition-Potsdam Study.
Dietrich, S., Floegel, A., Weikert, C., Pischon, T., Boeing, H. and Drogan, D.
Hypertension 68 (2): 471-477. August 2016

Random survival forest in practice: a method for modelling complex metabolomics data in time to event analysis.
Dietrich, S., Floegel, A., Troll, M., Kühn, T., Rathmann, W., Peters, A., Sookthai, D., von Bergen, M., Kaaks, R., Adamski, J., Prehn, C., Boeing, H., Schulze, M.B., Illig, T., Pischon, T., Knueppel, S., Wang-Sattler, R. and Drogan, D.
International Journal of Epidemiology 45 (5): 1406-1420. October 2016

Neprilysin is a mediator of alternative renin-angiotensin-system activation in the murine and human kidney.
Domenig, O., Manzel, A., Grobe, N., Königshausen, E., Kaltenecker, C.C., Kovarik, J.J., Stegbauer, J., Gurley, S.B., van Oyen, D., Antlanger, M., Bader, M., Motta-Santos, D., Santos, R.A., Elased, K.M., Säemann, M.D., Linker, R.A. and Poglitsch, M.
Scientific Reports 6 : 33678. 21 September 2016

Interaction of ARC and Daxx: a novel endogenous target to preserve motor function and cell loss after focal brain ischemia in mice.
Donath, S., An, J., Lee, S.L.L., Gertz, K., Datwyler, A.L., Harms, U., Mueller, S., Farr, T.D., Fuechtemeier, M., Lättig-Tünnemann, G., Lips, J., Foddis, M., Mosch, L., Bernard, R., Grittner, U., Balkaya, M., Kronenberg, G., Dirnagl, U., Endres, M. and Harms, C.
Journal of Neuroscience 36 (31): 8132-8148. 3 August 2016

Technologies to study genetics and molecular pathways.
Dorn, C., Grunert, M., Dopazo, A., Sanchez-Cabo, F., Gatto, A., Vazquez, J., Rickert-Sperling, S. and Lara-Pezzi, E.
In: Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways. Springer, Vienna, 251-269. ISBN 978-3-7091-1882-5 2016

Human genetics of tetralogy of fallot and double outlet right ventricle.
Dorn, C., Perrot, A. and Rickert-Sperling, S.
In: Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways. Springer, Vienna, 403-416. ISBN 978-3-7091-1882-5 2016

CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
Drachsler, M., Kleber, S., Mateos, A., Volk, K., Mohr, N., Chen, S., Cirovic, B., Tuettenberg, J., Gieffers, C., Sykora, J., Wirtz, C.R., Mueller, W., Synowitz, M. and Martin-Villalba, A.
Cell Death & Disease 7 : e2209. 28 April 2016

Insulin-like growth factor 1 and insulin-like growth factor-binding protein 3 in relation to the risk of type 2 diabetes mellitus: Results from the EPIC-Potsdam Study.
Drogan, D., Schulze, M.B., Boeing, H. and Pischon, T.
American Journal of Epidemiology 183 (6): 553-560. 15 March 2016

Does cortisol modulate emotion recognition and empathy?
Duesenberg, M., Weber, J., Schulze, L., Schaeuffele, C., Roepke, S., Hellmann-Regen, J., Otte, C. and Wingenfeld, K.
Psychoneuroendocrinology 66 : 221-227. April 2016

Basic modelling principles: deterministic models.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of calcium signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 97-161. ISBN 978-3-319-29645-6 2016

Hierarchical and stochastic modelling.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of calcium signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 163-205. ISBN 978-3-319-29645-6 2016

Models of calcium signalling.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland. ISBN 978-3-319-29645-6 2016

Muscle.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of Calcium Signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 295-336. ISBN 978-3-319-29645-6 2016

Neurons and other excitable cells.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of Calcium Signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 337-385. ISBN 978-3-319-29645-6 2016

Nonexcitable cells.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of Calcium Signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 245-294. ISBN 978-3-319-29645-6 2016

Nonlinear dynamics of calcium.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of calcium signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 207-242. ISBN 978-3-319-29645-6 2016

Some background physiology.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of calcium signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 3-27. ISBN 978-3-319-29645-6 2016

The calcium toolbox.
Dupont, G., Falcke, M., Kirk, V. and Sneyd, J.
In: Models of calcium signalling. Interdisciplinary Applied Mathematics, 43 . Springer, Cham, Switzerland, 29-96. ISBN 978-3-319-29645-6 2016

Epigenomic profiling of human CD4(+) T cells supports a linear differentiation model and highlights molecular regulators of memory development.
Durek, P., Nordström, K., Gasparoni, G., Salhab, A., Kressler, C., de Almeida, M., Bassler, K., Ulas, T., Schmidt, F., Xiong, J., Glažar, P., Klironomos, F., Sinha, A., Kinkley, S., Yang, X., Arrigoni, L., Amirabad, A.., Ardakani, F.B., Feuerbach, L., Gorka, O., Ebert, P., Müller, F., Li, N., Frischbutter, S., Schlickeiser, S., Cendon, C., Fröhler, S., Felder, B., Gasparoni, N., Imbusch, C.D., Hutter, B., Zipprich, G., Tauchmann, Y., Reinke, S., Wassilew, G., Hoffmann, U., Richter, A.S., Sieverling, L., Chang, H.D., Syrbe, U., Kalus, U., Eils, J., Brors, B., Manke, T., Ruland, J., Lengauer, T., Rajewsky, N., Chen, W., Dong, J., Sawitzki, B., Chung, H.R., Rosenstiel, P., Schulz, M.H., Schultze, J.L., Radbruch, A., Walter, J., Hamann, A. and Polansky, J.K.
Immunity 45 (5): 1148-1161. 15 November 2016

CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M., Yu, Y., Milanovic, M., Schönlein, M., Rosenfeldt, M.T., Dörr, J.R., Kaufmann, A.M., Dörken, B. and Schmitt, C.A.
Molecular Cancer Therapeutics 15 (5): 1074-1081. May 2016

Ethyl cellulose nanocarriers and nanocrystals differentially deliver dexamethasone into intact, tape-stripped or sodium lauryl sulfate-exposed ex vivo human skin - assessment by intradermal microdialysis and extraction from the different skin layers.
Döge, N., Hönzke, S., Schumacher, F., Balzus, B., Colombo, M., Hadam, S., Rancan, F., Blume-Peytavi, U., Schäfer-Korting, M., Schindler, A., Rühl, E., Skov, P.S., Church, M.K., Hedtrich, S., Kleuser, B., Bodmeier, R. and Vogt, A.
Journal of Controlled Release 242 : 25-34. 28 November 2016

Kinin receptors in skin wound healing.
da Soley, B., Morais, R.L.T., Pesquero, J.B., Bader, M., Otuki, M.F. and Cabrini, D.A.
Journal of Dermatological Science 82 (2): 95-105. May 2016

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: dominant roles of p50 and p52 revealed by genome-wide analyses.
de Oliveira, K.A.P., Kaergel, E., Heinig, M., Fontaine, J.F., Patone, G., Muro, E.M., Mathas, S., Hummel, M., Andrade-Navarro, M.A., Hübner, N. and Scheidereit, C.
Genome Medicine 8 (1): 28. 17 March 2016

E

Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes.
Ebstein, F., Textoris-Taube, K., Keller, C., Golnik, R., Vigneron, N., Van den Eynde, B.J., Schuler-Thurner, B., Schadendorf, D., Lorenz, F.K.M., Uckert, W., Urban, S., Lehmann, A., Albrecht-Koepke, N., Janek, K., Henklein, P., Niewienda, A., Kloetzel, P.M. and Mishto, M.
Scientific Reports 6 : 24032. 6 April 2016

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L., Czajkowski, M.T., Barth, C., Müller, P.M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016

Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak and augments drug response.
Einsele-Scholz, S., Malmsheimer, S., Bertram, K., Stehle, D., Johaenning, J., Manz, M., Daniel, P.T., Gillissen, B.F., Schulze-Osthoff, K. and Essmann, F.
Journal of Cell Science 129 (11): 2213-2223. 1 June 2016

Subunit-selective NMDA receptor signaling through BRAG1 and BRAG2 during synapse maturation.
Elagabani, M.N., Briševac, D., Kintscher, M., Pohle, J., Köhr, G., Schmitz, D. and Kornau, H.C.
Journal of Biological Chemistry 291 (17): 9105-9118. 22 April 2016

Integrin signalling regulates YAP and TAZ to control skin homeostasis.
Elbediwy, A., Vincent-Mistiaen, Z.I., Spencer-Dene, B., Stone, R.K., Boeing, S., Wculek, S.K., Cordero, J., Tan, E.H., Ridgway, R., Brunton, V.G., Sahai, E., Gerhardt, H., Behrens, A., Malanchi, I., Sansom, O.J. and Thompson, B.J.
Development 143 (10): 1674-1687. 15 May 2016

Evaluation of a portable armband device to assess resting energy expenditure in patients with anorexia nervosa.
Elbelt, U., Haas, V., Hofmann, T., Stengel, A., Berger, H., Jeran, S. and Klapp, B.F.
Nutrition in Clinical Practice 31 (3): 362-367. June 2016

Kaliopenic nephropathy revisited.
Elitok, S., Bieringer, M., Schneider, W. and Luft, F.C.
Clinical Kidney Journal 9 (4): 543-546. August 2016

Ranking of dystonia severity by pairwise video comparison.
Ellermeyer, T., Otte, K., Heinrich, F., Mansow-Model, S., Kayser, B., Lipp, A., Seidel, A., Krause, P., Lauritsch, K., Gusho, E., Paul, F., Kühn, A.A., Brandt, A.U. and Schmitz-Hübsch, T.
Movement Disorders Clinical Practice 3 (6): 587-595. November 2016

The European Hematology Association Roadmap for European Hematology Research: a consensus document.
Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Doehner, H., Duyvene' de Wit, T., Eichinger, S., Fibbe, W., Green, T., de Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Salles, G. and Schuringa, J.J.
Haematologica 101 (2): 115-208. February 2016

Full-length dysferlin transfer by the hyperactive Sleeping Beauty transposase restores dysferlin-deficient muscle.
Escobar, H., Schöwel, V., Spuler, S., Marg, A. and Izsvák, Z.
Molecular Therapy - Nucleic Acids 5 : e277. 19 January 2016

Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.
Esteves de Lima, J., Bonnin, M.A., Birchmeier, C. and Duprez, D.
eLife 5 : e15593. 24 August 2016

Characterization of a single genomic locus encoding the clustered protocadherin receptor diversity in Xenopus tropicalis.
Etlioglu, H.E., Sun, W., Huang, Z., Chen, W. and Schmucker, D.
G3 : Genes Genomes Genetics 6 (8): 2309-2318. 1 August 2016

A balance between secreted inhibitors and edge sensing controls gastruloid self-organization.
Etoc, F., Metzger, J., Ruzo, A., Kirst, C., Yoney, A., Ozair, M.Z., Brivanlou, A.H. and Siggia, E.D.
Developmental Cell 39 (3): 302-315. 7 November 2016

Non-equilibrium steady states of stochastic processes with intermittent resetting.
Eule, S. and Metzger, J.J.
New Journal of Physics 18 (3): 033006. March 2016

F

The genomic landscape of core-binding factor acute myeloid leukemias.
Faber, Z.J., Chen, X., Gedman, A.L., Boggs, K., Cheng, J., Ma, J., Radtke, I., Chao, J.R., Walsh, M.P., Song, G., Andersson, A.K., Dang, J., Dong, L., Liu, Y., Huether, R., Cai, Z., Mulder, H., Wu, G., Edmonson, M., Rusch, M., Qu, C., Li, Y., Vadodaria, B., Wang, J., Hedlund, E., Cao, X., Yergeau, D., Nakitandwe, J., Pounds, S.B., Shurtleff, S., Fulton, R.S., Fulton, L.L., Easton, J., Parganas, E., Pui, C.H., Rubnitz, J.E., Ding, L., Mardis, E.R., Wilson, R.K., Gruber, T.A., Mullighan, C.G., Schlenk, R.F., Paschka, P., Döhner, K., Döhner, H., Bullinger, L., Zhang, J., Klco, J.M. and Downing, J.R.
Nature Genetics 48 (12): 1551-1556. December 2016

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma.
Fabian, J., Opitz, D., Althoff, K., Lodrini, M., Hero, B., Volland, R., Beckers, A., de Preter, K., Decock, A., Patil, N., Abba, M., Kopp-Schneider, A., Astrahantseff, K., Wünschel, J., Pfeil, S., Ercu, M., Künkele, A., Hu, J., Thole, T., Schweizer, L., Mechtersheimer, G., Carter, D., Cheung, B.B., Popanda, O., von Deimling, A., Koster, J., Versteeg, R., Schwab, M., Marshall, G.M., Speleman, F., Erb, U., Zoeller, M., Allgayer, H., Simon, T., Fischer, M., Kulozik, A.E., Eggert, A., Witt, O., Schulte, J.H. and Deubzer, H.E.
Oncotarget 7 (41): 66344-66359. 11 October 2016

Concentration profiles of actin-binding molecules in lamellipodia.
Falcke, M.
Physica D: Nonlinear Phenomena 318-319 : 50-57. 1 April 2016

A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis.
Fang, L., Zhu, Q., Neuenschwander, M., Specker, E., Wulf-Goldenberg, A., Weis, W.I., von Kries, J.P. and Birchmeier, W.
Cancer Research 76 (4): 891-901. 15 February 2016

Immunological memory: lessons from the past and a look to the future.
Farber, D.L., Netea, M.G., Radbruch, A., Rajewsky, K. and Zinkernagel, R.M.
Nature Reviews Immunology 16 (2): 124-128. February 2016

Single-vesicle imaging reveals different transport mechanisms between glutamatergic and GABAergic vesicles.
Farsi, Z., Preobraschenski, J., van den Bogaart, G., Riedel, D., Jahn, R. and Woehler, A.
Science 351 (6276): 981-984. 26 February 2016

Generation of human induced pluripotent stem cell line from a patient with a long QT syndrome type 2.
Fatima, A., Ivanyuk, D., Herms, S., Heilmann-Heimbach, S., O'Shea, O., Chapman, C., Izsvák, Z., Farr, M., Hescheler, J. and Šarić, T.
Stem Cell Research 16 (2): 304-307. March 2016

Vitamin D supplementation improves pathophysiology in a rat model of preeclampsia.
Faulkner, J.L., Cornelius, D.C., Amaral, L.M., Harmon, A.C., Cunningham, M.W., Darby, M.M., Ibrahim, T., Thomas, D.S., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 310 (4): R346-R354. 15 February 2016

Higher-resolution MR elastography reveals early mechanical signatures of neuroinflammation in patients with clinically isolated syndrome.
Fehlner, A., Behrens, J.R., Streitberger, K.J., Papazoglou, S., Braun, J., Bellmann-Strobl, J., Ruprecht, K., Paul, F., Würfel, J. and Sack, I.
Journal of Magnetic Resonance Imaging 44 (1): 51-58. July 2016

The impact of epistemological beliefs and cognitive ability on recall and critical evaluation of scientific information.
Feinkohl, I., Flemming, D., Cress, U. and Kimmerle, J.
Cognitive Processing 17 (2): 213-223. May 2016

Reheating breakfast: Age and multitasking on a computer-based and a non-computer-based task.
Feinkohl, I., Cress, U. and Kimmerle, J.
Computers in Human Behavior 55 (Pt A): 432-438. February 2016

Obesity and post-operative cognitive dysfunction: a systematic review and meta-analysis.
Feinkohl, I., Winterer, G. and Pischon, T.
Diabetes/Metabolism Research and Reviews 32 (6): 643-651. September 2016

The translational potential of microRNAs as biofluid markers of urological tumours.
Fendler, A., Stephan, C., Yousef, G.M., Kristiansen, G. and Jung, K.
Nature Reviews Urology 13 (12): 734-752. December 2016

SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin.
Ferone, G., Song, J.Y., Sutherland, K.D., Bhaskaran, R., Monkhorst, K., Lambooij, J.P., Proost, N., Gargiulo, G. and Berns, A.
Cancer Cell 30 (4): 519-532. 10 October 2016

Advanced light microscopy core facilities: Balancing service, science and career.
Ferrando-May, E., Hartmann, H., Reymann, J., Ansari, N., Utz, N., Fried, H.U., Kukat, C., Peychl, J., Liebig, C., Terjung, S., Laketa, V., Sporbert, A., Weidtkamp-Peters, S., Schauss, A., Zuschratter, W. and Avilov, S.
Microscopy Research and Technique 79 (6): 463-479. June 2016

Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene.
Ferrario, C.M., VonCannon, J.L., Jiao, Y., Ahmad, S., Bader, M., Dell'Italia, L.J., Groban, L. and Varagic, J.
American Journal of Physiology Heart and Circulatory Physiology 310 (8): H995-H1002. 15 April 2016

Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL network phase II trial.
Ferrero, S., Pastore, A., Scholz, C.W., Forstpointner, R., Pezzutto, A., Bergmann, L., Truemper, L., Finke, J., Keller, U., Ghione, P., Passera, R., Hiddemann, W., Weigert, O., Unterhalt, M. and Dreyling, M.
Leukemia 30 (4): 984-987. April 2016

Cancer cachexia-when proteasomal inhibition is not enough.
Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (3): 239-245. June 2016

Normal volumes and microstructural integrity of deep gray matter structures in AQP4+ NMOSD.
Finke, C., Heine, J., Pache, F., Lacheta, A., Borisow, N., Kuchling, J., Bellmann-Strobl, J., Ruprecht, K., Brandt, A.U. and Paul, F.
Neurology Neuroimmunology & Neuroinflammation 3 (3): e229. June 2016

Structural hippocampal damage following anti-N-methyl-D-aspartate receptor encephalitis.
Finke, C., Kopp, U.A., Pajkert, A., Behrens, J.R., Leypoldt, F., Wuerfel, J.T., Ploner, C.J., Prüss, H. and Paul, F.
Biological Psychiatry 79 (9): 727-734. 1 May 2016

Hyper-activation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage.
Finzel, A., Grybowski, A., Strasen, J., Cristiano, E. and Loewer, A.
Molecular Biology of the Cell 27 (15): 2360-2367. 1 August 2016

Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18.
Flegel, C., Vogel, F., Hofreuter, A., Wojcik, S., Schoeder, C., Kieć-Kononowicz, K., Brockmeyer, N.H., Müller, C.E., Becker, C., Altmüller, J., Hatt, H. and Gisselmann, G.
Scientific Reports 6 : 32255. 30 August 2016

DC generation from peripheral blood mononuclear cells in patients with chronic myeloid leukemia: Influence of interferons on DC yield and functional properties.
Floercken, A., Kopp, J., Kölsch, U., Meisel, C., Dörken, B., Pezzutto, A. and Westermann, J.
Human Vaccines & Immunotherapeutics 12 (5): 1117-1123. 3 May 2016

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Fox, R.G., Lytle, N.K., Jaquish, D.V., Park, F.D., Ito, T., Bajaj, J., Koechlein, C.S., Zimdahl, B., Yano, M., Kopp, J., Kritzik, M., Sicklick, J., Sander, M., Grandgenett, P.M., Hollingsworth, M.A., Shibata, S., Pizzo, D., Valasek, M., Sasik, R., Scadeng, M., Okano, H., Kim, Y., MacLeod, A.R., Lowy, A.M. and Reya, T.
Nature 534 (7607): 407-411. 16 June 2016

Blood flow boosts BMP signaling to keep vessels in shape.
Franco, C.A. and Gerhardt, H.
Journal of Cell Biology 214 (7): 793-795. 26 September 2016

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling.
Franco, C.A., Jones, M.L., Bernabeu, M.O., Vion, A.C., Barbacena, P., Fan, J., Mathivet, T., Fonseca, C.G., Ragab, A., Yamaguchi, T.P., Coveney, P.V., Lang, R.A. and Gerhardt, H.
eLife 5 : e07727. 4 February 2016

Formation of new chromatin domains determines pathogenicity of genomic duplications.
Franke, M., Ibrahim, D.M., Andrey, G., Schwarzer, W., Heinrich, V., Schoepflin, R., Kraft, K., Kempfer, R., Jerkovic, I., Chan, W.L., Spielmann, M., Timmermann, B., Wittler, L., Kurth, I., Cambiaso, P., Zuffardi, O., Houge, G., Lambie, L., Brancati, F., Pombo, A., Vingron, M., Spitz, F. and Mundlos, S.
Nature 538 (7624): 265-269. 13 October 2016

Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis.
Fritsche-Guenther, R., Witzel, F., Kempa, S., Brummer, T., Sers, C. and Blüthgen, N.
Oncotarget 7 (7): 7960-7969. 20 January 2016

G

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features.
Gaidzik, V.I., Teleanu, V., Papaemmanuil, E., Weber, D., Paschka, P., Hahn, J., Wallrabenstein, T., Kolbinger, B., Köhne, C.H., Horst, H.A., Brossart, P., Held, G., Kündgen, A., Ringhoffer, M., Götze, K., Rummel, M., Gerstung, M., Campbell, P., Kraus, J.M., Kestler, H.A., Thol, F., Heuser, M., Schlegelberger, B., Ganser, A., Bullinger, L., Schlenk, R.F., Döhner, K. and Döhner, H.
Leukemia 30 (11): 2160-2168. November 2016

Benign infantile seizures and paroxysmal dyskinesia caused by an SCN8A mutation.
Gardella, E., Becker, F., Møller, R.S., Schubert, J., Lemke, J.R., Larsen, L.H.G., Eiberg, H., Nothnagel, M., Thiele, H., Altmüller, J., Syrbe, S., Merkenschlager, A., Bast, T., Steinhoff, B., Nürnberg, P., Mang, Y., Bakke Møller, L., Gellert, P., Heron, S.E., Dibbens, L.M., Weckhuysen, S., Dahl, H.A., Biskup, S., Tommerup, N., Hjalgrim, H., Lerche, H., Beniczky, S. and Weber, Y.G.
Annals of Neurology 79 (3): 428-436. March 2016

Polycomb and lung cancer: when the dosage makes the (kind of) poison.
Gargiulo, G., Citterio, E. and Serresi, M.
Molecular & Cellular Oncology 3 (3): e1152345. May 2016

Contemporary use and results of intra-aortic balloon pump counterpulsation.
Gargiulo, G., Stabile, E., Perrino, C., Scudiero, F., Scudiero, L., Schiattarella, G.G., Franzone, A., Sannino, A., Giugliano, G., Trimarco, B. and Esposito, G.
Minerva Cardioangiologica 64 (1): 84-91. February 2016

Identification and re-addressing of a transcriptionally permissive locus in the porcine genome.
Garrels, W., Mukherjee, A., Holler, S., Cleve, N., Talluri, T.R., Barg-Kues, B., Diederich, M., Köhler, P., Petersen, B., Lucas-Hahn, A., Niemann, H., Izsvák, Z., Ivics, Z. and Kues, W.A.
Transgenic Research 25 (1): 63-70. February 2016

Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns.
Gartlan, K.H., Krashias, G., Wegmann, F., Hillson, W.R., Scherer, E.M., Greenberg, P.D., Eisenbarth, S.C., Moghaddam, A.E. and Sattentau, Q.J.
Vaccine 34 (19): 2188-2196. 27 April 2016

Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo.
Gebala, V., Collins, R., Geudens, I., Phng, L.K. and Gerhardt, H.
Nature Cell Biology 18 (4): 443-450. April 2016

Mapping the landscape of a eukaryotic degronome.
Geffen, Y., Appleboim, A., Gardner, R.G., Friedman, N., Sadeh, R. and Ravid, T.
Molecular Cell 63 (6): 1055-1065. 15 September 2016

Structural changes and lack of HCN1 channels in the binaural auditory brainstem of the naked mole-rat (Heterocephalus glaber).
Gessele, N., Garcia-Pino, E., Omerbasic, D., Park, T.J. and Koch, U.
PLoS ONE 11 (1): e0146428. 13 January 2016

Targeted application of human genetic variation can improve red blood cell production from stem cells.
Giani, F.C., Fiorini, C., Wakabayashi, A., Ludwig, L.S., Salem, R.M., Jobaliya, C.D., Regan, S.N., Ulirsch, J.C., Liang, G., Steinberg-Shemer, O., Guo, M.H., Esko, T., Tong, W., Brugnara, C., Hirschhorn, J.N., Weiss, M.J., Zon, L.I., Chou, S.T., French, D.L., Musunuru, K. and Sankaran, V.G.
Cell Stem Cell 18 (1): 73-78. 7 January 2016

TERT core promotor mutations in early-onset bladder cancer.
Giedl, J., Rogler, A., Wild, A., Riener, M.O., Filbeck, T., Burger, M., Ruemmele, P., Hurst, C., Knowles, M., Hartmann, A., Zinnall, U. and Stoehr, R.
Journal of Cancer 7 (8): 915-920. 7 May 2016

Putting chromatin in its place: the pioneer factor NeuroD1 modulates chromatin state to drive cell fate decisions.
Glahs, A. and Zinzen, R.P.
EMBO Journal 35 (1): 1-3. 4 January 2016

SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
Glerup, S., Bolcho, U., Molgaard, S., Bøggild, S., Vaegter, C.B., Smith, A.H., Nieto-Gonzalez, J.L., Ovesen, P.L., Pedersen, L.F., Fjorback, A.N., Kjolby, M., Login, H., Holm, M.M., Andersen, O.M., Nyengaard, J.R., Willnow, T.E., Jensen, K. and Nykjaer, A.
Molecular Psychiatry 21 (12): 1740-1751. December 2016

Genome-wide profiling reveals remarkable parallels between insertion site selection properties of the MLV retrovirus and the piggyBac transposon in primary human CD4(+) T cells.
Gogol-Döring, A., Ammar, I., Gupta, S., Bunse, M., Miskey, C., Chen, W., Uckert, W., Schulz, T.F., Izsvák, Z. and Ivics, Z.
Molecular Therapy 24 (3): 592-606. March 2016

CancerResource - updated database of cancer-relevant proteins, mutations and interacting drugs.
Gohlke, B.O., Nickel, J., Otto, R., Dunkel, M. and Preissner, R.
Nucleic Acids Research 44 (D1): D932-D937. 4 January 2016

Recent progress in structure and dynamics of dual-membrane-spanning bacterial nanomachines.
Gold, V. and Kudryashev, M.
Current Opinion in Structural Biology 39 : 1-7. August 2016

Natural killer cell reduction and uteroplacental vasculopathy.
Golic, M., Haase, N., Herse, F., Wehner, A., Vercruysse, L., Pijnenborg, R., Balogh, A., Saether, P.C., Dissen, E., Luft, F.C., Przybyl, L., Park, J.K., Alnaes-Katjavivi, P., Staff, A.C., Verlohren, S., Henrich, W., Muller, D.N. and Dechend, R.
Hypertension 68 (4): 964-973. October 2016

Tumor necrosis factor-α, uterine natural killer cells, and pregnancy.
Golic, M., Luft, F.C. and Dechend, R.
Hypertension 68 (5): 1108-1109. November 2016

Re: Sun-Kui Ke et al. TRiPping over vasotonus regulation in the lung.
Gollasch, M. and Kuebler, W.M.
Respiratory Physiology & Neurobiology 227 : 71-72. 15 June 2016

Crimea report leaves readers in the cold.
Goushcha, A., Goloverda, G.Z., Kotsyuba, O., Perepichka, D.F., Seumenicht, O. and Ladokhin, A.S.
Science 352 (6287): 780-781. 13 May 2016

A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes.
Grabundzija, I., Messing, S.A., Thomas, J., Cosby, R.L., Bilic, I., Miskey, C., Gogol-Döring, A., Kapitonov, V., Diem, T., Dalda, A., Jurka, J., Pritham, E.J., Dyda, F., Izsvák, Z. and Ivics, Z.
Nature Communications 7 : 10716. 2 March 2016

Structural decoding of the netrin-1/UNC5 interaction and its therapeutical implications in cancers.
Grandin, M., Meier, M., Delcros, J.G., Nikodemus, D., Reuten, R., Patel, T.R., Goldschneider, D., Orriss, G., Krahn, N., Boussouar, A., Abes, R., Dean, Y., Neves, D., Bernet, A., Depil, S., Schneiders, F., Poole, K., Dante, R., Koch, M., Mehlen, P. and Stetefeld, J.
Cancer Cell 29 (2): 173-185. 8 February 2016

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Grauel, M.K., Maglione, M., Reddy-Alla, S., Willmes, C.G., Brockmann, M.M., Trimbuch, T., Rosenmund, T., Pangalos, M., Vardar, G., Stumpf, A., Walter, A.M., Rost, B.R., Eickholt, B.J., Haucke, V., Schmitz, D., Sigrist, S.J. and Rosenmund, C.
Proceedings of the National Academy of Sciences of the United States of America 113 (41): 11615-11620. 11 October 2016

Comparative DNA methylation and gene expression analysis identifies novel genes for structural congenital heart diseases.
Grunert, M., Dorn, C., Cui, H., Dunkel, I., Schulz, K., Schoenhals, S., Sun, W., Berger, F., Chen, W. and Sperling, S.R.
Cardiovascular Research 112 (1): 464-477. 1 October 2016

Cardiac transcription factors and regulatory networks.
Grunert, M., Dorn, C. and Rickert-Sperling, S.
In: Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways. Springer, Vienna, 139-152. ISBN 978-3-7091-1882-5 2016

Plankton networks driving carbon export in the oligotrophic ocean.
Guidi, L., Chaffron, S., Bittner, L., Eveillard, D., Larhlimi, A., Roux, S., Darzi, Y., Audic, S., Berline, L., Brum, J., Coelho, L.P., Espinoza, J.C.I., Malviya, S., Sunagawa, S., Dimier, C., Kandels-Lewis, S., Picheral, M., Poulain, J., Searson, S., Stemmann, L., Not, F., Hingamp, P., Speich, S., Follows, M., Karp-Boss, L., Boss, E., Ogata, H., Pesant, S., Weissenbach, J., Wincker, P., Acinas, S.G., Bork, P., de Vargas, C., Iudicone, D., Sullivan, M.B., Raes, J., Karsenti, E., Bowler, C. and Gorsky, G.
Nature 532 (7600): 465-470. 28 April 2016

Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA): a 2 x 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol.
Gulati, G., Heck, S.L., Ree, A.H., Hoffmann, P., Schulz-Menger, J., Fagerland, M.W., Gravdehaug, B., von Knobelsdorff-Brenkenhoff, F., Bratland, Å., Storås, T.H., Hagve, T.A., Røsjø, H., Steine, K., Geisler, J. and Omland, T.
European Heart Journal 37 (21): 1671-1680. June 2016

Splenic marginal zone granulocytes acquire an accentuated neutrophil B cell-helper phenotype in chronic lymphocytic leukemia.
Gätjen, M., Brand, F., Grau, M., Gerlach, K., Kettritz, R., Westermann, J., Anagnostopoulos, I., Lenz, P., Lenz, G., Höpken, U.E. and Rehm, A.
Cancer Research 76 (18): 5253-5265. 15 September 2016

Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination.
Gödde, K., Gschwend, O., Puchkov, D., Pfeffer, C.K., Carleton, A. and Jentsch, T.J.
Nature Communications 7 : 12043. 8 July 2016

AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Götz, F., Roske, Y., Schulz, M.S., Autenrieth, K., Bertinetti, D., Faelber, K., Zühlke, K., Kreuchwig, A., Kennedy, E., Krause, G., Daumke, O., Herberg, F.W., Heinemann, U. and Klussmann, E.
Biochemical Journal 473 (13): 1881-1894. 28 June 2016

H

Relaxin treatment in an Ang-II-based transgenic reeclamptic-rat model.
Haase, N., Golic, M., Herse, F., Rugor, J., Linz, D., Solano, M.E., Müller, D.N. and Dechend, R.
PLoS ONE 11 (3): e0150743. 10 March 2016

Aptamer BC 007 - a broad spectrum neutralizer of pathogenic autoantibodies against G-protein-coupled receptors.
Haberland, A., Holtzhauer, M., Schlichtiger, A., Bartel, S., Schimke, I., Mueller, J., Dandel, M., Luppa, P.B. and Wallukat, G.
European Journal of Pharmacology 789 : 37-45. 15 October 2016

Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders.
Hadar, R., Edemann-Callesen, H., Reinel, C., Wieske, F., Voget, M., Popova, E., Sohr, R., Avchalumov, Y., Priller, J., van Riesen, C., Puls, I., Bader, M. and Winter, C.
Scientific Reports 6 : 39145. 15 December 2016

Characterization, treatment patterns, and patient-related outcomes of patients with Fragile X syndrome in Germany: final results of the observational EXPLAIN-FXS study.
Haessler, F., Gaese, F., Huss, M., Kretschmar, C., Brinkman, M., Peters, H., Elstner, S., Colla, M. and Pittrow, D.
BMC Psychiatry 16 (1): 318. 10 September 2016

Diffusion pseudotime robustly reconstructs lineage branching.
Haghverdi, L., Büttner, M., Wolf, F.A., Buettner, F. and Theis, F.J.
Nature Methods 13 (10): 845-848. October 2016

The role of microglia and macrophages in glioma maintenance and progression.
Hambardzumyan, D., Gutmann, D.H. and Kettenmann, H.
Nature Neuroscience 19 (1): 20-27. January 2016

Role of the receptor Mas in macrophage-mediated inflammation in vivo.
Hammer, A., Yang, G., Friedrich, J., Kovacs, A., Lee, D.H., Grave, K., Jörg, S., Alenina, N., Grosch, J., Winkler, J., Gold, R., Bader, M., Manzel, A., Rump, L.C., Müller, D.N., Linker, R.A. and Stegbauer, J.
Proceedings of the National Academy of Sciences of the United States of America 113 (49): 14109-14114. 6 December 2016

Genomic resources for wild populations of the house mouse, Mus musculus and its close relative Mus spretus.
Harr, B., Karakoc, E., Neme, R., Teschke, M., Pfeifle, C., Pezer, Ž., Babiker, H., Linnenbrink, M., Montero, I., Scavetta, R., Abai, M.R., Molins, M.P., Schlegel, M., Ulrich, R.G., Altmüller, J., Franitza, M., Büntge, A., Künzel, S. and Tautz, D.
Scientific Data 3 : 160075. 13 September 2016

A circuit basis for morphogenesis.
Harrington, K.I.S.
Theoretical Computer Science 633 : 28-36. 20 June 2016

The clinical outcome study for dysferlinopathy: an international multicenter study.
Harris, E., Bladen, C.L., Mayhew, A., James, M., Bettinson, K., Moore, U., Smith, F.E., Rufibach, L., Cnaan, A., Bharucha-Goebel, D.X., Blamire, A.M., Bravver, E., Carlier, P.G., Day, J.W., Díaz-Manera, J., Eagle, M., Grieben, U., Harms, M., Jones, K.J., Lochmüller, H., Mendell, J.R., Mori-Yoshimura, M., Paradas, C., Pegoraro, E., Pestronk, A., Salort-Campana, E., Schreiber-Katz, O., Semplicini, C., Spuler, S., Stojkovic, T., Straub, V., Takeda, S., Rocha, C.T., Walter, M.C. and Bushby, K.
Neurology Genetics 2 (4): e89. 4 August 2016

SORLA regulates calpain-dependent degradation of synapsin.
Hartl, D., Nebrich, G., Klein, O., Stephanowitz, H., Krause, E. and Rohe, M.
Alzheimer's & Dementia 12 (9): 952-963. September 2016

Alternative splicing substantially diversifies the transcriptome during early photomorphogenesis and correlates with the energy availability in arabidopsis.
Hartmann, L., Drewe-Boss, P., Wiessner, T., Wagner, G., Geue, S., Lee, H.C., Obermueller, D.M., Kahles, A., Behr, J., Sinz, F.H., Raetsch, G. and Wachter, A.
Plant Cell 28 (11): 2715-2734. November 2016

The Lupus autoantigen La prevents Mis-channeling of tRNA fragments into the human microRNA pathway.
Hasler, D., Lehmann, G., Murakawa, Y., Klironomos, F., Jakob, L., Grässer, F.A., Rajewsky, N., Landthaler, M. and Meister, G.
Molecular Cell 63 (1): 110-124. 7 July 2016

Characterizing the phenotype of multiple sclerosis-associated depression in comparison with idiopathic major depression.
Hasselmann, H., Bellmann-Strobl, J., Ricken, R., Oberwahrenbrock, T., Rose, M., Otte, C., Adli, M., Paul, F., Brandt, A.U., Finke, C. and Gold, S.M.
Multiple Sclerosis Journal 22 (11): 1476-1484. October 2016

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit.
Hatzold, J., Beleggia, F., Herzig, H., Altmüller, J., Nürnberg, P., Bloch, W., Wollnik, B. and Hammerschmidt, M.
eLife 5 : e14277. 15 July 2016

Branched-chain and aromatic amino acids, insulin resistance and liver specific ectopic fat storage in overweight to obese subjects.
Haufe, S., Witt, H., Engeli, S., Kaminski, J., Utz, W., Fuhrmann, J.C., Rein, D., Schulz-Menger, J., Luft, F.C., Boschmann, M. and Jordan, J.
Nutrition Metabolism and Cardiovascular Diseases 26 (7): 637-642. July 2016

Intrinsic deregulation of vascular smooth muscle and myofibroblast differentiation in mesenchymal stromal cells from patients with systemic sclerosis.
Hegner, B., Schaub, T., Catar, R., Kusch, A., Wagner, P., Essin, K., Lange, C., Riemekasten, G. and Dragun, D.
PLoS ONE 11 (4): e0153101. 7 April 2016

Immunoadsorption of agonistic autoantibodies against α1-adrenergic receptors in patients with mild to moderate dementia.
Hempel, P., Heinig, B., Jerosch, C., Decius, I., Karczewski, P., Kassner, U., Kunze, R., Steinhagen-Thiessen, E. and Bimmler, M.
Therapeutic Apheresis and Dialysis 20 (5): 523-529. October 2016

CMR first-pass perfusion for suspected inducible myocardial ischemia.
Hendel, R.C., Friedrich, M.G., Schulz-Menger, J., Zemmrich, C., Bengel, F., Berman, D.S., Camici, P.G., Flamm, S.D., Le Guludec, D., Kim, R., Lombardi, M., Mahmarian, J., Sechtem, U. and Nagel, E.
JACC: Cardiovascular Imaging 9 (11): 1338-1348. 7 November 2016

Complex regional pain syndrome and dysautonomia in a 14-year-old girl responsive to therapeutic plasma exchange.
Hendrickson, J.E., Hendrickson, E.T., Gehrie, E.A., Sidhu, D., Wallukat, G., Schimke, I. and Tormey, C.A.
Journal of Clinical Apheresis 31 (4): 368-374. August 2016

Targeting MYCN-driven transcription by BET-bromodomain inhibition.
Henssen, A., Althoff, K., Odersky, A., Beckers, A., Koche, R., Speleman, F., Schäfers, S., Bell, E., Nortmeyer, M., Westermann, F., De Preter, K., Florin, A., Heukamp, L., Spruessel, A., Astrahanseff, K., Lindner, S., Sadowski, N., Schramm, A., Astorgues-Xerri, L., Riveiro, M.E., Eggert, A., Cvitkovic, E. and Schulte, J.H.
Clinical Cancer Research 22 (10): 2470-2481. May 2016

Cytoarchitecture and probability maps of the human medial orbitofrontal cortex.
Henssen, A., Zilles, K., Palomero-Gallagher, N., Schleicher, A., Mohlberg, H., Gerboga, F., Eickhoff, S.B., Bludau, S. and Amunts, K.
Cortex 75 : 87-112. February 2016

Forward genetic screen of human transposase genomic rearrangements.
Henssen, A.G., Jiang, E., Zhuang, J., Pinello, L., Socci, N.D., Koche, R., Gonen, M., Villasante, C.M., Armstrong, S.A., Bauer, D.E., Weng, Z. and Kentsis, A.
BMC Genomics 17 : 548. 4 August 2016

Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.
Herling, C.D., Klaumünzer, M., Rocha, C.K., Altmüller, J., Thiele, H., Bahlo, J., Kluth, S., Crispatzu, G., Herling, M., Schiller, J., Engelke, A., Tausch, E., Döhner, H., Fischer, K., Goede, V., Nürnberg, P., Reinhardt, H.C., Stilgenbauer, S., Hallek, M. and Kreuzer, K.A.
Blood 128 (3): 395-404. 21 July 2016

DNA damage signaling instructs polyploid macrophage fate in granulomas.
Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Münke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S., Sieweke, M.H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M.M., Voll, R.E., Deshmukh, S.D., Prinz, M., Goldmann, T., Hölscher, C., Hauser, A.E., Lopez-Contreras, A.J., Grün, D., Gorgoulis, V., Diefenbach, A., Henneke, P. and Triantafyllopoulou, A.
Cell 167 (5): 1264-1280. 17 November 2016

Identification of signature volatiles to discriminate Candida albicans, glabrata, krusei and tropicalis using gas chromatography and mass spectrometry.
Hertel, M., Hartwig, S., Schuette, E., Gillissen, B., Preissner, R., Schmidt-Westhausen, A.M., Paris, S., Kastner, I. and Preissner, S.
Mycoses 59 (2): 117-126. February 2016

Detection of signature volatiles for cariogenic microorganisms.
Hertel, M., Preissner, R., Gillissen, B., Schmidt-Westhausen, A.M., Paris, S. and Preissner, S.
European Journal of Clinical Microbiology & Infectious Diseases 35 (2): 235-244. February 2016

CX3CR1-dependent recruitment of mature NK cells into the central nervous system contributes to control autoimmune neuroinflammation.
Hertwig, L., Hamann, I., Romero-Suarez, S., Millward, J.M., Pietrek, R., Chanvillard, C., Stuis, H., Pollok, K., Ransohoff, R.M., Cardona, A.E. and Infante-Duarte, C.
European Journal of Immunology 46 (8): 1984-1996. August 2016

Distinct functionality of neutrophils in multiple sclerosis and neuromyelitis optica.
Hertwig, L., Pache, F., Romero-Suarez, S., Stuerner, K.H., Borisow, N., Behrens, J., Bellmann-Strobl, J., Seeger, B., Asselborn, N., Ruprecht, K., Millward, J.M., Infante-Duarte, C. and Paul, F.
Multiple Sclerosis Journal 22 (2): 160-173. February 2016

Physiology unmasks hypertension.
Heusser, K., Brinkmann, J., Topalidis, W., Menne, J., Haller, H., Berliner, D.., Luft, F.C., Tank, J. and Jordan, J.
Hypertension 68 (2): 252-256. August 2016

Preserved autonomic cardiovascular regulation with cardiac pacemaker inhibition: a crossover trial using high-fidelity cardiovascular phenotyping.
Heusser, K., Tank, J., Brinkmann, J., Schroeder, C., May, M., Grosshennig, A., Wenzel, D., Diedrich, A., Sweep, F.C.G.J., Mehling, H., Luft, F.C. and Jordan, J.
Journal of the American Heart Association 5 (1): e002674. 13 January 2016

Identifying prognostic SNPs in clinical cohorts: complementing univariate ynalyses by resampling and multivariable modeling.
Hieke, S., Benner, A., Schlenk, R.F., Schumacher, M., Bullinger, L. and Binder, H.
PLoS ONE 11 (5): e0155226. May 2016

Integrating multiple molecular sources into a clinical risk prediction signature by extracting complementary information.
Hieke, S., Benner, A., Schlenl, R.F., Schumacher, M., Bullinger, L. and Binder, H.
BMC Bioinformatics 17 (1): 327. 30 August 2016

Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.
Hinze, F., Dieterich, C., Radke, M.H., Granzier, H. and Gotthardt, M.
Journal of Molecular Medicine 94 (12): 1349-1358. December 2016

Left ventricular noncompaction.
Hoedemaekers, Y.M. and Klaassen, S.
In: Clinical Cardiogenetics. Springer, Cham, 113-135. ISBN 978-3-319-44202-0 2 December 2016

Early developmental stress negatively affects neuronal recruitment to avian song system nucleus HVC.
Honarmand, M., Thompson, C.K., Schatton, A., Kipper, S. and Scharff, C.
Developmental Neurobiology 76 (1): 107-118. January 2016

Mass spectrometry based metabolomics comparison of liver grafts from donors after circulatory death (DCD) and donors after brain death (DBD) used in human orthotopic liver transplantation.
Hrydziuszko, O., Perera, M.T.P.R., Laing, R., Kirwan, J., Silva, M.A., Richards, D.A., Murphy, N., Mirza, D.F. and Viant, M.R.
PLoS ONE 11 (11): e0165884. 11 November 2016

Super-resolution ribosome profiling reveals unannotated translation events in Arabidopsis.
Hsu, P.Y., Calviello, L., Wu, H.Y.L., Li, F.W., Rothfels, C.J., Ohler, U. and Benfey, P.N.
Proceedings of the National Academy of Sciences of the United States of America 113 (45): E7126-E7135. 8 November 2016

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.
Hu, H., Haas, S.A., Chelly, J., Van Esch, H., Raynaud, M., de Brouwer, A.P.M., Weinert, S., Froyen, G., Frints, S.G.M., Laumonnier, F., Zemojtel, T., Love, M.I., Richard, H., Emde, A.K., Bienek, M., Jensen, C., Hambrock, M., Fischer, U., Langnick, C., Feldkamp, M., Wissink-Lindhout, W., Lebrun, N., Castelnau, L., Rucci, J., Montjean, R., Dorseuil, O., Billuart, P., Stuhlmann, T., Shaw, M., Corbett, M.A., Gardner, A., Willis-Owen, S., Tan, C., Friend, K.L., Belet, S., van Roozendaal, K.E.P., Jimenez-Pocquet, M., Moizard, M.P., Ronce, N., Sun, R., O'Keeffe, S., Chenna, R., van Bömmel, A., Goeke, J., Hackett, A., Field, M., Christie, L., Boyle, J., Haan, E., Nelson, J., Turner, G., Baynam, G., Gillessen-Kaesbach, G., Mueller, U., Steinberger, D., Budny, B., Badura-Stronka, M., Latos-Bieleńska, A., Ousager, L.B., Wieacker, P., Rodríguez Criado, G., Bondeson, M.L., Annerén, G., Dufke, A., Cohen, M., Van Maldergem, L., Vincent-Delorme, C., Echenne, B., Simon-Bouy, B., Kleefstra, T., Willemsen, M., Fryns, J.P., Devriendt, K., Ullmann, R., Vingron, M., Wrogemann, K., Wienker, T.F., Tzschach, A., van Bokhoven, H., Gecz, J., Jentsch, T.J., Chen, W., Ropers, H.H. and Kalscheuer, V.M.
Molecular Psychiatry 21 (1): 133-148. January 2016

Delivery of therapeutics targeting the mRNA-binding protein HuR using 3DNA nanocarriers suppresses ovarian tumor growth.
Huang, Y.H., Peng, W., Furuuchi, N., Gerhart, J., Rhodes, K., Mukherjee, N., Jimbo, M., Gonye, G.E., Brody, J.R., Getts, R.C. and Sawicki, J.A.
Cancer Research 76 (6): 1549-1559. 15 March 2016

SNX27 and SORLA interact to reduce amyloidogenic subcellular distribution and processing of amyloid precursor protein.
Huang, T.Y., Zhao, Y., Li, X., Wang, X., Tseng, I.C., Thompson, R., Tu, S., Willnow, T.E., Zhang, Y.W. and Xu, H.
Journal of Neuroscience 36 (30): 7996-8011. 27 July 2016

Protein abundance control by non-coding antisense transcription.
Huber, F., Bunina, D., Gupta, I., Khmelinskii, A., Meurer, M., Theer, P., Steinmetz, L.M. and Knop, M.
Cell Reports 15 (12): 2625-2636. 21 June 2016

ETE 3: reconstruction, analysis and visualization of phylogenomic data.
Huerta-Cepas, J., Serra, F. and Bork, P.
Molecular Biology and Evolution 33 (6): 1635-1638. June 2016

eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences.
Huerta-Cepas, J., Szklarczyk, D., Forslund, K., Cook, H., Heller, D., Walter, M.C., Rattei, T., Mende, D.R., Sunagawa, S., Kuhn, M., Jensen, L.J., von Mering, C. and Bork, P.
Nucleic Acids Research 44 (D1): D286-D293. 4 January 2016

Retinal imaging and axonal degeneration in later onset multiple sclerosis.
Huhn, K., Laemmer, R., Zimmermann, H., Lämmer, A., Waschbisch, A., Utz, K., Gieß, R.M., Paul, F., Linker, R.A. and Lee, D.H.
Journal of the Neurological Sciences 370 : 1-6. 15 November 2016

Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria: a German-Austrian retrospective multicenter study in patients with a clinically isolated syndrome.
Huss, A.M., Halbgebauer, S., Öckl, P., Trebst, C., Spreer, A., Borisow, N., Harrer, A., Brecht, I., Balint, B., Stich, O., Schlegel, S., Retzlaff, N., Winkelmann, A., Roesler, R., Lauda, F., Yildiz, O., Voss, E., Muche, R., Rauer, S., Bergh, F.T., Otto, M., Paul, F., Wildemann, B., Kraus, J., Ruprecht, K., Stangel, M., Buttmann, M., Zettl, U.K. and Tumani, H.
Journal of Neurology 263 (12): 2499-2504. December 2016

Activation of peroxisome proliferator-activated receptor-δ as novel therapeutic strategy to prevent in-stent restenosis and stent thrombosis.
Hytönen, J., Leppänen, O., Braesen, J.H., Schunck, W.H., Mueller, D., Jung, F., Mrowietz, C., Jastroch, M., von Bergwelt-Baildon, M., Kappert, K., Heuser, A., Drenckhahn, J.D., Pieske, B., Thierfelder, L., Ylä-Herttuala, S. and Blaschke, F.
Arteriosclerosis Thrombosis and Vascular Biology 36 (8): 1534-1548. August 2016

Influence of Th2 cytokines on the cornified envelope, tight junction proteins, and ß-defensins in filaggrin-deficient skin equivalents.
Hönzke, S., Wallmeyer, L., Ostrowski, A., Radbruch, M., Mundhenk, L., Schäfer-Korting, M. and Hedtrich, S.
Journal of Investigative Dermatology 136 (3): 631-639. March 2016

Hermes regulates axon sorting in the optic tract by post-trancriptional regulation of Neuropilin 1.
Hörnberg, H., Cioni, J.M., Harris, W.A. and Holt, C.E.
Journal of Neuroscience 36 (50): 12697-12706. 14 December 2016

I

Using light sheet fluorescence microscopy to image zebrafish eye development.
Icha, J., Schmied, C., Sidhaye, J., Tomancak, P., Preibisch, S. and Norden, C.
Journal of Visualized Experiments 2016 (110): e53966. 10 April 2016

TLR2 controls random motility, while TLR7 regulates chemotaxis of microglial cells via distinct pathways.
Ifuku, M., Buonfiglioli, A., Jordan, P., Lehnardt, S. and Kettenmann, H.
Brain Behavior and Immunity 58 : 338-347. November 2016

MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer.
Ilm, K., Fuchs, S., Mudduluru, G. and Stein, U.
Oncotarget 7 (33): 53443-53458. 16 August 2016

SL2: an interactive webtool for modeling of missing segments in proteins.
Ismer, J., Rose, A.S., Tiemann, J.K.S., Goede, A., Preissner, R. and Hildebrand, P.W.
Nucleic Acids Research 44 (W1): W390-W394. 8 July 2016

Pluripotency and the endogenous retrovirus HERVH: Conflict or serendipity?
Izsvák, Z., Wang, J., Singh, M., Mager, D.L. and Hurst, L.D.
BioEssays 38 (1): 109-117. January 2016

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Automated annotation and evaluation of in-source mass spectra in GC/atmospheric pressure chemical ionization-MS-based metabolomics.
Jaeger, C., Hoffmann, F., Schmitt, C.A. and Lisec, J.
Analytical Chemistry 88 (19): 9386-9390. 4 October 2016

Data integration for identification of important transcription factors of STAT6-mediated cell fate decisions.
Jargosch, M., Kroeger, S., Gralinska, E., Klotz, U., Fang, Z., Chen, W., Leser, U., Selbig, J., Groth, D. and Baumgrass, R.
Genetics and Molecular Research 15 (2): gmr.15028493. 24 June 2016

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome.
Jarius, S., Kleiter, I., Ruprecht, K., Asgari, N., Pitarokoili, K., Borisow, N., Hümmert, M.W., Trebst, C., Pache, F., Winkelmann, A., Beume, L.A., Ringelstein, M., Stich, O., Aktas, O., Korporal-Kuhnke, M., Schwarz, A., Lukas, C., Haas, J., Fechner, K., Buttmann, M., Bellmann-Strobl, J., Zimmermann, H., Brandt, A.U., Franciotta, D., Schanda, K., Paul, F., Reindl, M. and Wildemann, B.
Journal of Neuroinflammation 13 (1): 281. 1 November 2016

Screening for MOG-IgG and 27 other anti-glial and anti-neuronal autoantibodies in 'pattern II multiple sclerosis' and brain biopsy findings in a MOG-IgG-positive case.
Jarius, S., Metz, I., König, F.B., Ruprecht, K., Reindl, M., Paul, F., Brück, W. and Wildemann, B.
Multiple Sclerosis Journal 22 (12): 1541-1549. October 2016

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome.
Jarius, S., Ruprecht, K., Kleiter, I., Borisow, N., Asgari, N., Pitarokoili, K., Pache, F., Stich, O., Beume, L.A., Hümmert, M.W., Ringelstein, M., Trebst, C., Winkelmann, A., Schwarz, A., Buttmann, M., Zimmermann, H., Kuchling, J., Franciotta, D., Capobianco, M., Siebert, E., Lukas, C., Korporal-Kuhnke, M., Haas, J., Fechner, K., Brandt, A.U., Schanda, K., Aktas, O., Paul, F., Reindl, M. and Wildemann, B.
Journal of Neuroinflammation 13 (1): 280. 28 October 2016

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin.
Jarius, S., Ruprecht, K., Kleiter, I., Borisow, N., Asgari, N., Pitarokoili, K., Pache, F., Stich, O., Beume, L.A., Hümmert, M.W., Trebst, C., Ringelstein, M., Aktas, O., Winkelmann, A., Buttmann, M., Schwarz, A., Zimmermann, H., Brandt, A.U., Franciotta, D., Capobianco, M., Kuchling, J., Haas, J., Korporal-Kuhnke, M., Lillevang, S.T., Fechner, K., Schanda, K., Paul, F., Wildemann, B. and Reindl, M.
Journal of Neuroinflammation 13 (1): 279. 26 September 2016

A pipeline for PAR-CLIP data analysis.
Jens, M.
Methods in Molecular Biology 1358 : 197-207. 2016

VRACs and other ion channels and transporters in the regulation of cell volume and beyond.
Jentsch, T.J.
Nature Reviews Molecular Cell Biology 17 (5): 293-307. May 2016

VRAC: molecular identification as LRRC8 heteromers with differential functions.
Jentsch, T.J., Lutter, D., Planells-Cases, R., Ullrich, F. and Voss, F.K.
Pflugers Archiv 468 (3): 385-393. March 2016

Prediction of activity related energy expenditure using accelerometer derived physical activity under free-living conditions-a systematic review.
Jeran, S., Steinbrecher, A. and Pischon, T.
International Journal of Obesity 40 (8): 1187-1197. August 2016

Amyloid-β(1-42) aggregation initiates its cellular uptake and cytotoxicity.
Jin, S., Kedia, N., Illes-Toth, E., Haralampiev, I., Prisner, S., Herrmann, A., Wanker, E.E. and Bieschke, J.
Journal of Biological Chemistry 291 (37): 19590-19606. 9 September 2016

Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.
Jung, B., Messias, A.C., Schorpp, K., Geerlof, A., Schneider, G., Saur, D., Hadian, K., Sattler, M., Wanker, E.E., Hasenöder, S. and Lickert, H.
Scientific Reports 6 : 22540. 2 March 2016

Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes.
Juryńczyk, M., Weinshenker, B., Akman-Demir, G., Asgari, N., Barnes, D., Boggild, M., Chaudhuri, A., D'hooghe, M., Evangelou, N., Geraldes, R., Illes, Z., Jacob, A., Kim, H.J., Kleiter, I., Levy, M., Marignier, R., McGuigan, C., Murray, K., Nakashima, I., Pandit, L., Paul, F., Pittock, S., Selmaj, K., de Sèze, J., Siva, A., Tanasescu, R., Vukusic, S., Wingerchuk, D., Wren, D., Leite, I. and Palace, J.
Journal of Neurology 263 (1): 140-149. January 2016

Environmental factors in autoimmune diseases and their role in multiple sclerosis.
Jörg, S., Grohme, D.A., Erzler, M., Binsfeld, M., Haghikia, A., Müller, D.N., Linker, R.A. and Kleinewietfeld, M.
Cellular and Molecular Life Sciences 73 (24): 4611-4622. December 2016

High salt drives Th17 responses in experimental autoimmune encephalomyelitis without impacting myeloid dendritic cells.
Jörg, S., Kissel, J., Manzel, A., Kleinewietfeld, M., Haghikia, A., Gold, R., Müller, D.N. and Linker, R.A.
Experimental Neurology 279 : 212-222. May 2016

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The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
Kabat, A.M., Harrison, O.J., Riffelmacher, T., Moghaddam, A.E., Pearson, C.F., Laing, A., Abeler-Dörner, L., Forman, S.P., Grencis, R.K., Sattentau, Q., Simon, A.K., Pott, J. and Maloy, K.J.
eLife 5 : e12444. 11 March 2016

Longitudinal study to assess the clinical significance of MSI2 expression in chronic myeloid keukemia patients.
Kaeda, J., Ringel, F., Oberender, C., Gresse, M., Amini, L., Schwarz, M., Doerken, B. and le Coutre, P.
Acta Haematologica 136 (1): 62-64. June 2016

Diagnosis and treatment of cardiac echinococcosis.
Kahlfuss, S., Flieger, R.R., Roepke, T.K. and Yilmaz, K.
Heart 102 (17): 1348-1353. September 2016

Pericardial tamponade in an adult suffering from acute mumps infection.
Kahlfuss, S., Flieger, R.R., Mankertz, A., Yilmaz, K. and Roepke, T.K.
Case Reports in Medicine 2016 : 7980936. 12 October 2016

Genome wide conditional mouse knockout resources.
Kaloff, C., Anastassiadis, K., Ayadi, A., Baldock, R., Beig, J., Birling, M.C., Bradley, A., Brown, S.D.M., Buerger, A., Bushell, W., Chiani, F., Collins, F.S., Doe, B., Eppig, J.T., Finnell, R.H., Fletcher, C., Flicek, P., Fray, M., Friedel, R.H., Gambadoro, A., Gates, H., Hansen, J., Herault, Y., Hicks, G.G., Hoerlein, A., Hrabe de Angelis, M., Iyer, V., de Jong, P.J., Koscielny, G., Kuehn, R., Liu, P., Lloyd, K.C.K, Lopez, R.G., Marschall, S., Martinez, S., McKerlie, C., Meehan, T., von Melchner, H., Moore, M., Murray, S.A., Nagy, A., Nutter, L.M.J., Pavlovic, G., Pombero, A., Prosser, H., Ramirez-Solis, R., Ringwald, M., Rosen, B., Rosenthal, N., Rossant, J., Ruiz Noppinger, P., Ryder, E., Skarnes, W.C., Schick, J., Schnuetgen, F., Schofield, P., Seisenberger, C., Selloum, M., Smedley, D., Simpson, E.M., Stewart, A.F., Teboul, L., Tocchini Valentini, G.P., Valenzuela, D., West, A.P. and Wurst, W.
Drug Discovery Today: Disease Models 20 : 3-12. 2016

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Kaminski, M.M., Tosic, J., Kresbach, C., Engel, H., Klockenbusch, J., Müller, A.L., Pichler, R., Grahammer, F., Kretz, O., Huber, T.B., Walz, G., Arnold, S.J. and Lienkamp, S.S.
Nature Cell Biology 18 (12): 1269-1280. December 2016

Convergent evolution within CEA gene families in mammals: hints for species-specific selection pressures.
Kammerer, R., Herse, F. and Zimmermann, W.
In: Evolutionary Biology : Convergent Evolution, Evolution of Complex Traits, Concepts and Methods. Springer International Publishing, Switzerland, 37-53. ISBN 978-3-319-41323-5 2016

M-CSF improves protection against bacterial and fungal infections after hematopoietic stem/progenitor cell transplantation.
Kandalla, P.K., Sarrazin, S., Molawi, K., Berruyer, C., Redelberger, D., Favel, A., Bordi, C., de Bentzmann, S. and Sieweke, M.H.
Journal of Experimental Medicine 213 (11): 2269-2279. 10 October 2016

Bacteriophage tailspikes and bacterial O-antigens as a model system to study weak-affinity protein-polysaccharide interactions.
Kang, Y., Gohlke, U., Engström, O., Hamark, C., Scheidt, T., Kunstmann, S., Heinemann, U., Widmalm, G., Santer, M. and Barbirz, S.
Journal of the American Chemical Society 138 (29): 9109-9118. 27 July 2016

Systems genetics analysis of a recombinant inbred mouse cell culture panel reveals Wnt pathway member Lrp6 as a regulator of adult hippocampal precursor cell proliferation.
Kannan, S., Nicola, Z., Overall, R.W., Ichwan, M., Ramírez-Rodríguez, G., Grzyb, A., Patone, G., Saar, K., Hübner, N. and Kempermann, G.
Stem Cells 34 (3): 674-684. March 2016

G-quadruplex prediction in E. coli genome reveals a conserved putative G-quadruplex-hairpin-duplex switch.
Kaplan, O.I., Berber, B., Hekim, N. and Doluca, O.
Nucleic Acids Research 44 (19): 9083-9095. 2 November 2016

Autoionization in time-dependent density-functional theory.
Kapoor, V.
Physical Review A 93 (6): 063408. 8 June 2016

Cseq-simulator: a data simulator for CLIP-Seq experiments.
Kassuhn, W., Ohler, U. and Drewe, P.
In: Pacific Symposium on Biocomputing (PSB) 2016, 4-8 Jan 2016, The Big Island of Hawaii, USA. January 2016

Regional regulation of filiform tongue papillae development by Ikkα/Irf6.
Kawasaki, M., Kawasaki, K., Oommen, S., Blackburn, J., Watanabe, M., Nagai, T., Kitamura, A., Maeda, T., Liu, B., Schmidt-Ullrich, R., Akiyama, T., Inoue, J.I., Hammond, N.L., Sharpe, P.T. and Ohazama, A.
Developmental Dynamics 245 (9): 937-946. September 2016

SPIRE, a modular pipeline for eQTL analysis of RNA-Seq data, reveals a regulatory hotspot controlling miRNA expression in C. elegans.
Kel, I., Chang, Z., Galluccio, N., Romeo, M., Beretta, S., Diomede, L., Mezzelani, A., Milanesi, L., Dieterich, C. and Merelli, I.
Molecular BioSystems 12 (11): 3447-3458. 1 November 2016

Power estimation for non-standardized multisite studies.
Keshavan, A., Paul, F., Beyer, M.K., Zhu, A.H., Papinutto, N., Shinohara, R.T., Stern, W., Amann, M., Bakshi, R., Bischof, A., Carriero, A., Comabella, M., Crane, J.C., D'Alfonso, S., Demaerel, P., Dubois, B., Filippi, M., Fleischer, V., Fontaine, B., Gaetano, L., Goris, A., Graetz, C., Gröger, A., Groppa, S., Hafler, D.A., Harbo, H.F., Hemmer, B., Jordan, K., Kappos, L., Kirkish, G., Llufriu, S., Magon, S., Martinelli-Boneschi, F., McCauley, J., Montalban, X., Muhlau, M., Pelletier, D., Pattany, P.M., Pericak-Vance, M., Rebeix, I., Rocca, M., Rovira, A., Schlaeger, R., Saiz, A., Sprenger, T., Stecco, A., Uitdehaag, B.M.J., Villoslada, P., Wattjes, M.P., Weiner, H., Wuerfel, J., Zimmer, C., Zipp, F., Hauser, S., Oksenberg, J.R. and Henry, R.G.
NeuroImage 134 : 281-294. 1 July 2016

FENS Forum 2018 in Berlin.
Kettenmann, H. and Pflueger, H.J.
Neuroforum 22 (4): 109-109. December 2016

Glial cells: neuroglia.
Kettenmann, H. and Verkhratsky, A.
In: Neuroscience in the 21st Century: From Basic to Clinical. UNSPECIFIED, 547-578. ISBN 978-1-4939-3473-7 27 October 2016

The case: nonneurological tetraplegia.
Kettritz, R., Gollasch, B., Zaks, M. and Luft, F.C.
Kidney International 89 (3): 727-728. March 2016

Neutral serine proteases of neutrophils.
Kettritz, R.
Immunological Reviews 273 (1): 232-248. September 2016

Thymus-derived regulatory T cells are positively selected on natural self-antigen through cognate interactions of high functional avidity.
Kieback, E., Hilgenberg, E., Stervbo, U., Lampropoulou, V., Shen, P., Bunse, M., Jaimes, Y., Boudinot, P., Radbruch, A., Klemm, U., Kühl, A.A., Liblau, R., Hoevelmeyer, N., Anderton, S.M., Uckert, W. and Fillatreau, S.
Immunity 44 (5): 1114-1126. 17 May 2016

reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4(+) memory T cells.
Kinkley, S., Helmuth, J., Polansky, J.K., Dunkel, I., Gasparoni, G., Froehler, S., Chen, W., Walter, J., Hamann, A. and Chung, H.R.
Nature Communications 7 : 12514. 17 August 2016

Benefits and risks of aliskiren treatment in patients with type 2 diabetes: analyses of the 3A registry.
Kistner, I., Zeymer, U., Dechend, R., Hagedorn, I., Riemer, T., Bramlage, P., Pittrow, D., Senges, J. and Schmieder, R.E.
Journal of Clinical Hypertension 18 (10): 1045-1053. October 2016

Chemical proteomics reveals ferrochelatase as a common off-target of kinase inhibitors.
Klaeger, S., Gohlke, B., Perrin, J., Gupta, V., Heinzlmeir, S., Helm, D., Qiao, H., Bergamini, G., Handa, H., Savitski, M.M., Bantscheff, M., Medard, G., Preissner, R. and Kuster, B.
ACS Chemical Biology 11 (5): 1245-1254. 20 May 2016

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.
Klawitter, S., Fuchs, N.V., Upton, K.R., Muñoz-Lopez, M., Shukla, R., Wang, J., Garcia-Cañadas, M., Lopez-Ruiz, C., Gerhardt, D.J., Sebe, A., Grabundzija, I., Merkert, S., Gerdes, P., Pulgarin, J.A., Bock, A., Held, U., Witthuhn, A., Haase, A., Sarkadi, B., Löwer, J., Wolvetang, E.J., Martin, U., Ivics, Z., Izsvák, Z., Garcia-Perez, J.L., Faulkner, G.J. and Schumann, G.G.
Nature Communications 7 : 10286. 8 January 2016

Diagnostic criteria for Susac syndrome.
Kleffner, I., Dörr, J., Ringelstein, M., Gross, C.C., Böckenfeld, Y., Schwindt, W., Sundermann, B., Lohmann, H., Wersching, H., Promesberger, J., von Königsmarck, N., Alex, A., Guthoff, R., Frijns, C.J.M., Kappelle, L.J., Jarius, S., Wildemann, B., Aktas, O., Paul, F., Wiendl, H. and Duning, T.
Journal of Neurology Neurosurgery and Psychiatry 87 (12): 1287-1295. 25 December 2016

Optimization of the All-D peptide D3 for Aβ oligomer elimination.
Klein, A.N., Ziehm, T., Tusche, M., Buitenhuis, J., Bartnik, D., Boeddrich, A., Wiglenda, T., Wanker, E., Funke, S.A., Brener, O., Gremer, L., Kutzsche, J. and Willbold, D.
PLoS ONE 11 (4): e0153035. 22 April 2016

Early cortical changes in gamma oscillations in Alzheimer's disease.
Klein, A.S., Donoso, J.R., Kempter, R., Schmitz, D. and Beed, P.
Frontiers in Systems Neuroscience 10 : 83. 26 October 2016

Neuromyelitis optica: evaluation of 871 attacks and 1153 treatment courses.
Kleiter, I., Gahlen, A., Borisow, N., Fischer, K., Wernecke, K.D., Wegner, B., Hellwig, K., Pache, F., Ruprecht, K., Havla, J., Krumbholz, M., Kümpfel, T., Aktas, O., Hartung, H.P., Ringelstein, M., Geis, C., Kleinschnitz, C., Berthele, A., Hemmer, B., Angstwurm, K., Stellmann, J.P., Schuster, S., Stangel, M., Lauda, F., Tumani, H., Mayer, C., Zeltner, L., Ziemann, U., Linker, R., Schwab, M., Marziniak, M., Bergh, F.T., Hofstadt-van Oy, U., Neuhaus, O., Winkelmann, A., Marouf, W., Faiss, J., Wildemann, B., Paul, F., Jarius, S. and Trebst, C.
Annals of Neurology 79 (2): 206-216. February 2016

Monitoring von Blutparametern unter verlaufsmodifizierender MS-Therapie : Substanzspezifische Relevanz und aktuelle Handlungsempfehlungen [Monitoring of blood parameters under course-modified MS therapy : substance-specific relevance and current recommendations for action].
Klotz, L., Berthele, A., Brück, W., Chan, A., Flachenecker, P., Gold, R., Haghikia, A., Hellwig, K., Hemmer, B., Hohlfeld, R., Korn, T., Kümpfel, T., Lang, M., Limmroth, V., Linker, R.A., Meier, U., Meuth, S.G., Paul, F., Salmen, A., Stangel, M., Tackenberg, B., Tumani, H., Warnke, C., Weber, M.S., Ziemssen, T., Zipp, F. and Wiendl, H.
Nervenarzt 87 (6): 645-659. June 2016

Protein-protein interactions of PDE4 family members - Functions, interactions and therapeutic value.
Klussmann, E.
Cellular Signalling 28 (7): 713-718. July 2016

B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G., Liedgens, P., Korovkina, D., Seeger, J.M., Al-Baldawi, Y., Al-Maarri, M., Fritz, C., Vlantis, K., Bezhanova, S., Scheel, A.H., Wolz, O.O., Reimann, M., Möller, P., López, C., Schlesner, M., Lohneis, P., Weber, A.N.R., Trümper, L., Staudt, L.M., Ortmann, M., Pasparakis, M., Siebert, R., Schmitt, C.A., Klatt, A.R., Wunderlich, F.T., Schäfer, S.C., Persigehl, T., Montesinos-Rongen, M., Odenthal, M., Büttner, R., Frenzel, L.P., Kashkar, H. and Reinhardt, H.C.
Blood 127 (22): 2732-2741. 2 June 2016

Critical illness polyneuropathy in ICU patients is related to reduced motor nerve excitability caused by reduced sodium permeability.
Koch, S., Bierbrauer, J., Haas, K., Wolter, S., Grosskreutz, J., Luft, F.C., Spies, C.D., Fielitz, J. and Weber-Carstens, S.
Intensive Care Medicine Experimental 4 (1): 10. 20 May 2016

Xenopus as a model system for studying pancreatic development and diabetes.
Kofent, J. and Spagnoli, F.M.
Seminars in Cell & Developmental Biology 51 : 106-116. March 2016

The histone methyltransferase Setd7 promotes pancreatic progenitor identity.
Kofent, J., Zhang, J. and Spagnoli, F.M.
Development 143 (19): 3573-3581. 1 October 2016

Genetic association analysis based on a joint model of gene expression and blood pressure.
Konigorski, S., Yilmaz, Y.E. and Pischon, T.
BMC Proceedings 10 (Suppl 7): 289-294. 18 October 2016

Stem cells versus plasticity in liver and pancreas regeneration.
Kopp, J.L., Grompe, M. and Sander, M.
Nature Cell Biology 18 (3): 238-45. March 2016

Deletion of polycomb repressive complex 2 from mouse intestine causes loss of stem cells.
Koppens, M.A.J., Bounova, G., Gargiulo, G., Tanger, E., Janssen, H., Cornelissen-Steijger, P., Blom, M., Song, J.Y., Wessels, L.F.A. and van Lohuizen, M.
Gastroenterology 151 (4): 684-697. October 2016

Phase II trial of temsirolimus for relapsed/refractory primary CNS lymphoma.
Korfel, A., Schlegel, U., Herrlinger, U., Dreyling, M., Schmidt, C., von Baumgarten, L., Pezzutto, A., Grobosch, T., Kebir, S., Thiel, E., Martus, P. and Kiewe, P.
Journal of Clinical Oncology 34 (15): 1757-1763. 20 May 2016

Genetics, evolution and radiation: Crossing borders, the interdisciplinary legacy of Nikolay W. Timofeeff-Ressovsky.
Korogodina, V.L., Mothersill, C.E., Inge-Vechtomov, S.G. and Seymour, C.B.
Springer, Cham, Switzerland. ISBN 978-3-319-48837-0 2016

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children.
Korpela, K., Salonen, A., Virta, L.J., Kekkonen, R.A., Forslund, K., Bork, P. and de Vos, W.M.
Nature Communications 7 : 10410. 26 January 2016

Cellular and system biology of memory: Timing, molecules, and beyond.
Korte, M. and Schmitz, D.
Physiological Reviews 96 (2): 647-693. April 2016

Spontaneous Ca(2+) transients in mouse microglia.
Korvers, L., de Andrade Costa, A., Mersch, M., Matyash, V., Kettenmann, H. and Semtner, M.
Cell Calcium 60 (6): 396-406. December 2016

Functional interaction of CCAAT/enhancer-binding-protein-α basic region mutants with E2F transcription factors and DNA.
Kowenz-Leutz, E., Schuetz, A., Liu, Q., Knoblich, M., Heinemann, U. and Leutz, A.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1859 (7): 841-847. July 2016

Genetic causes of MCPH in consanguineous Pakistani families.
Kraemer, N., Picker-Minh, S., Abbasi, A.A., Froehler, S., Ninnemann, O., Khan, M.N., Ali, G., Chen, W. and Kaindl, A.M.
Clinical Genetics 89 (6): 744-745. June 2016

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.
Krause, C.J., Popp, O., Thirunarayanan, N., Dittmar, G., Lipp, M. and Mueller, G.
Oncotarget 7 (9): 10414-10432. 1 March 2016

Predictive and prognostic value of sPRR in patients with primary epithelial ovarian cancer.
Kreienbring, K., Franz, A., Richter, R., Dragun, D., Heidecke, H., Dechend, R., Mueller, D.N., Sehouli, J. and Braicu, E.I.
Analytical Cellular Pathology 2016 : 6845213. 2016

Bi-allelic truncating mutations in TANGO2 cause infancy-onset recurrent metabolic crises with encephalocardiomyopathy.
Kremer, L.S., Distelmaier, F., Alhaddad, B., Hempel, M., Iuso, A., Küpper, C., Mühlhausen, C., Kovacs-Nagy, R., Satanovskij, R., Graf, E., Berutti, R., Eckstein, G., Durbin, R., Sauer, S., Hoffmann, G.F., Strom, T.M., Santer, R., Meitinger, T., Klopstock, T., Prokisch, H. and Haack, T.B.
American Journal of Human Genetics 98 (2): 358-362. 4 February 2016

Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Kreye, J., Wenke, N.K., Chayka, M., Leubner, J., Murugan, R., Maier, N., Jurek, B., Ly, L.T., Brandl, D., Rost, B.R., Stumpf, A., Schulz, P., Radbruch, H., Hauser, A.E., Pache, F., Meisel, A., Harms, L., Paul, F., Dirnagl, U., Garner, C., Schmitz, D., Wardemann, H. and Prüss, H.
Brain 139 (10): 2641-2652. 1 October 2016

Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin.
Kronenberg, G., Mosienko, V., Gertz, K., Alenina, N., Hellweg, R. and Klempin, F.
European Archives of Psychiatry and Clinical Neuroscience 266 (3): 281-284. April 2016

A large deletion in RPGR causes XLPRA in Weimaraner dogs.
Kropatsch, R., Akkad, D.A., Frank, M., Rosenhagen, C., Altmüller, J., Nürnberg, P., Epplen, J.T. and Dekomien, G.
Canine Genetics and Epidemiology 3 : 7. 8 July 2016

MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia.
Krowiorz, K., Ruschmann, J., Lai, C., Ngom, M., Maetzig, T., Martins, V., Scheffold, A., Schneider, E., Pochert, N., Miller, C., Palmqvist, L., Staffas, A., Mulaw, M., Bohl, S.R., Buske, C., Heuser, M., Kraus, J., O'Neill, K., Hansen, C.L., Petriv, O.I., Kestler, H., Döhner, H., Bullinger, L., Döhner, K., Humphries, R.K., Rouhi, A. and Kuchenbauer, F.
Blood Cancer Journal 6 (12): e508. December 2016

Tomo-seq: A method to obtain genome-wide expression data with spatial resolution.
Kruse, F., Junker, J.P., van Oudenaarden, A. and Bakkers, J.
Methods in Cell Biology 135 : 299-307. 2016

Neutropenic sepsis in the ICU: Outcome predictors in a two-phase model and microbiology findings.
Kruse, J.M., Jenning, T., Rademacher, S., Arnold, R., Schmitt, C.A., Jörres, A., Enghard, P. and Oppert, M.
Critical Care Research and Practice 2016 : 8137850. 2016

ERK1 as a therapeutic target for dendritic cell vaccination against high-grade gliomas.
Ku, M.C., Edes, I., Bendix, I., Pohlmann, A., Waiczies, H., Prozorovski, T., Günther, M., Martin, C., Pagès, G., Wolf, S.A., Kettenmann, H., Uckert, W., Niendorf, T. and Waiczies, S.
Molecular Cancer Therapeutics 15 (8): 1975-1987. August 2016

Untersuchung des Farbsehens bei akuter einseitiger Neuritis nervi optici mittels eines webbasierten Farbsehtests [Investigation of color vision in acute unilateral optic neuritis using a web-based color vision test].
Kuchenbecker, J., Blum, M. and Paul, F.
Ophthalmologe 113 (3): 223-229. March 2016

The structure of the mouse serotonin 5-HT3 receptor in lipid vesicles.
Kudryashev, M., Castaño-Díez, D., Deluz, C., Hassaine, G., Grasso, L., Graf-Meyer, A., Vogel, H. and Stahlberg, H.
Structure 24 (1): 165-170. 5 January 2016

TALENs : Methods and Protocols.
Kuehn, R., Wurst, W. and Wefers, B.
Methods in Molecular Biology, 1338 . Springer, New York. ISBN 978-1-4939-2931-3 2016

Interindividual variation in DNA methylation at a putative POMC metastable epiallele is associated with obesity.
Kuehnen, P., Handke, D., Waterland, R.A., Hennig, B.J., Silver, M., Fulford, A.J., Dominguez-Salas, P., Moore, S.E., Prentice, A.M., Spranger, J., Hinney, A., Hebebrand, J., Heppner, F.L., Walzer, L., Groetzinger, C., Gromoll, J., Wiegand, S., Grueters, A. and Krude, H.
Cell Metabolism 24 (3): 502-509. 13 September 2016

The SIDER database of drugs and side effects.
Kuhn, M., Letunic, I., Jensen, L.J. and Bork, P.
Nucleic Acids Research 44 (D1): D1075-D1079. 4 January 2016

MOCAT2: a metagenomic assembly, annotation and profiling framework.
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Bioinformatics 32 (16): 2520-2523. 15 August 2016

Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin.
Kumar, S., Birol, M. and Miranker, A.D.
Chemical Communications 52 (38): 6391-6394. 11 May 2016

Foldamer-mediated manipulation of a pre-amyloid toxin.
Kumar, S., Birol, M., Schlamadinger, D.E., Wojcik, S.P., Rhoades, E. and Miranker, A.D.
Nature Communications 7 : 11412. 25 April 2016

Temporal modulation of collective cell behavior controls vascular network topology.
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eLife 5 : e13212. 24 February 2016

Neural progenitors adopt specific identities by directly repressing all alternative progenitor transcriptional programs.
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Developmental Cell 36 (6): 639-653. 21 March 2016

Novel ICD programming and inappropriate ICD therapy in CRT-D versus ICD patients: a MADIT-RIT sub-study.
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Divergent transcription and epigenetic directionality of human promoters.
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FEBS Journal 283 (23): 4214-4222. December 2016

Hemodynamics and salt-and-water balance link sodium storage and vascular dysfunction in salt-sensitive subjects.
Laffer, C.L., Scott, R.C., Titze, J.M., Luft, F.C. and Elijovich, F.
Hypertension 68 (1): 195-203. July 2016

Polyhydramnios, transient antenatal Bartter's syndrome, and MAGED2 mutations.
Laghmani, K., Beck, B.B., Yang, S.S., Seaayfan, E., Wenzel, A., Reusch, B., Vitzthum, H., Priem, D., Demaretz, S., Bergmann, K., Duin, L.K., Göbel, H., Mache, C., Thiele, H., Bartram, M.P., Dombret, C., Altmüller, J., Nürnberg, P., Benzing, T., Levtchenko, E., Seyberth, H.W., Klaus, G., Yigit, G., Lin, S.H., Timmer, A., de Koning, T.J., Scherjon, S.A., Schlingmann, K.P., Bertrand, M.J.M., Rinschen, M.M., de Backer, O., Konrad, M. and Kömhoff, M.
New England Journal of Medicine 374 (19): 1853-1863. 12 May 2016

A comprehensive comparison of general RNA-RNA interaction prediction methods.
Lai, D. and Meyer, I.M.
Nucleic Acids Research 44 (7): e61. 20 April 2016

Increased probability of co-occurrence of two rare diseases in consanguineous families and resolution of a complex phenotype by next generation sequencing.
Lal, D., Neubauer, B.A., Toliat, M.R., Altmüller, J., Thiele, H., Nürnberg, P., Kamrath, C., Schänzer, A., Sander, T., Hahn, A. and Nothnagel, M.
PLoS ONE 11 (1): e0146040. January 2016

Evaluation of presumably disease causing SCN1A variants in a cohort of common epilepsy syndromes.
Lal, D., Reinthaler, E.M., Dejanovic, B., May, P., Thiele, H., Lehesjoki, A.E., Schwarz, G., Riesch, E., Ikram, M.A., van Duijn, C.M., Uitterlinden, A.G., Hofman, A., Steinböck, H., Gruber-Sedlmayr, U., Neophytou, B., Zara, F., Hahn, A., Gormley, P., Becker, F., Weber, Y.G., Cilio, M.R., Kunz, W.S., Krause, R., Zimprich, F., Lemke, J.R., Nürnberg, P., Sander, T., Lerche, H. and Neubauer, B.A.
PLoS ONE 11 (3): e0150426. 18 March 2016

GPU-accelerated level-set segmentation.
Lamas-Rodríguez, J., Heras, D.B., Argüello, F., Kainmueller, D., Zachow, S. and Bóo, M.
Journal of Real-Time Image Processing 12 (1): 15-29. June 2016

Effects of Ncl. Basalis Meynert volume on the Trail-Making-Test are restricted to the left hemisphere.
Lammers, F., Mobascher, A., Musso, F., Shah, N.J., Warbrick, T., Zaborszky, L. and Winterer, G.
Brain and Behavior 6 (1): e00421. January 2016

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
Lange, C., Turrero Garcia, M., Decimo, I., Bifari, F., Eelen, G., Quaegebeur, A., Boon, R., Zhao, H., Boeckx, B., Chang, J., Wu, C., le Noble, F., Lambrechts, D., Dewerchin, M., Kuo, C.J., Huttner, W.B. and Carmeliet, P.
EMBO Journal 35 (9): 924-941. 2 May 2016

Decreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream.
Langenfurth, A., Gu, S., Bautze, V., Zhang, C., Neumann, J.E., Schüller, U., Stock, K., Wolf, S.A., Maier, A.M., Mastrella, G., Pak, A., Cheng, H., Kälin, R.E., Holmbeck, K., Strotmann, J., Kettenmann, H. and Glass, R.
Scientific Reports 6 : 32203. 30 August 2016

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment.
Le, H.Q., Ghatak, S., Yeung, C.Y.C., Tellkamp, F., Günschmann, C., Dieterich, C., Yeroslaviz, A., Habermann, B., Pombo, A., Niessen, C.M. and Wickström, S.A.
Nature Cell Biology 18 (8): 864-875. August 2016

Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia.
Lee, S.M., Nguyen, D., Anand, M., Kant, R., Koehncke, C., Lisewski, U., Roepke, T.K., Hu, Z. and Abbott, G.W.
Scientific Reports 6 : 23118. 17 March 2016

Generation of functional cardiomyocytes from the synoviocytes of patients with rheumatoid arthritis via induced pluripotent stem cells.
Lee, J., Jung, S.M., Ebert, A.D., Wu, H., Diecke, S., Kim, Y., Yi, H., Park, S.H. and Ju, J.H.
Scientific Reports 6 : 32669. 9 September 2016

Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancer-specific point mutation.
Leisegang, M., Engels, B., Schreiber, K., Yew, P.Y., Kiyotani, K., Idel, C., Arina, A., Duraiswamy, J., Weichselbaum, R.R., Uckert, W., Nakamura, Y. and Schreiber, H.
Clinical Cancer Research 22 (11): 2734-2743. 1 June 2016

Targeting human melanoma neoantigens by T cell receptor gene therapy.
Leisegang, M., Kammertoens, T., Uckert, W. and Blankenstein, T.
Journal of Clinical Investigation 126 (3): 854-858. 1 March 2016

MACC1 induces tumor progression in transgenic mice and colorectal cancer patients via increased pluripotency markers Nanog and Oct4.
Lemos, C., Hardt, M.S., Juneja, M., Voss, C., Foerster, S., Jerchow, B., Haider, W., Blaker, H. and Stein, U.
Clinical Cancer Research 22 (11): 2812-2824. 1 June 2016

Age-dependent differential expression of death-associated protein 6 (Daxx) in various peripheral tissues and different brain regions of C57BL/6 male mice.
Lessard-Beaudoin, M., Laroche, M., Demers, M.J., Duclos, C., Denault, J.B., Grenier, G., Riechers, S.P., Wanker, E.E. and Graham, R.K.
Biogerontology 17 (5): 817-828. November 2016

Organ-specific alteration in caspase expression and STK3 proteolysis during the aging process.
Lessard-Beaudoin, M., Laroche, M., Loudghi, A., Demers, M.J., Denault, J.B., Grenier, G., Riechers, S.P., Wanker, E.E. and Graham, R.K.
Neurobiology of Aging 47 : 50-62. November 2016

Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees.
Letunic, I. and Bork, P.
Nucleic Acids Research 44 (W1): W242-W245. 8 July 2016

The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach.
Levin, J., Maaß, S., Schuberth, M., Respondek, G., Paul, F., Mansmann, U., Oertel, W.H., Lorenzl, S., Krismer, F., Seppi, K., Poewe, W., Wenning, G., Giese, A., Boetzel, K. and Hoeglinger, G.
Journal of Neural Transmission 123 (4): 439-445. April 2016

Survival of Igα-deficient mature B cells requires BAFF-R function.
Levit-Zerdoun, E., Becker, M., Pohlmeyer, R., Wilhelm, I., Maity, P.C., Rajewsky, K., Reth, M. and Hobeika, E.
Journal of Immunology 196 (5): 2348-2360. 1 March 2016

Durable coexistence of donor and recipient strains after fecal microbiota transplantation.
Li, S.S., Zhu, A., Benes, V., Costea, P.I., Hercog, R., Hildebrand, F., Huerta-Cepas, J., Nieuwdorp, M., Salojaervi, J., Voigt, A.Y., Zeller, G., Sunagawa, S., de Vos, W.M. and Bork, P.
Science 352 (6285): 586-589. 29 April 2016

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Li, S., Garrett-Bakelman, F.E., Chung, S.S., Sanders, M.A., Hricik, T., Rapaport, F., Patel, J., Dillon, R., Vijay, P., Brown, A.L., Perl, A.E., Cannon, J., Bullinger, L., Luger, S., Becker, M., Lewis, I.D., To, L.B., Delwel, R., Löwenberg, B., Döhner, H., Döhner, K., Guzman, M.L., Hassane, D.C., Roboz, G.J., Grimwade, D., Valk, P.J.M., D'Andrea, R.J., Carroll, M., Park, C.Y., Neuberg, D., Levine, R., Melnick, A.M. and Mason, C.E.
Nature Medicine 22 (7): 792-9. July 2016

High-resolution expression map of the arabidopsis root reveals alternative splicing and lincRNA regulation.
Li, S., Yamada, M., Han, X., Ohler, U. and Benfey, P.N.
Developmental Cell 39 (4): 508-522. 21 November 2016

A clinical perspective: contribution of dysfunctional perivascular adipose tissue (PVAT) to cardiovascular risk.
Lian, X. and Gollasch, M.
Current Hypertension Reports 18 (11): 82. November 2016

Epigenetic profiling in CD4+ and CD8+ T cells from Graves' disease patients reveals changes in genes associated with T cell receptor signaling.
Limbach, M., Saare, M., Tserel, L., Kisand, K., Eglit, T., Sauer, S., Axelsson, T., Syvänen, A.C., Metspalu, A., Milani, L. and Peterson, P.
Journal of Autoimmunity 67 : 46-56. February 2016

Lowered pH leads to fusion peptide release and a highly dynamic intermediate of influenza hemagglutinin.
Lin, X.C., Noel, J.K., Wang, Q.H., Ma, J.P. and Onuchic, J.N.
Journal of Physical Chemistry B 120 (36): 9654-9660. 15 September 2016

Extending the dynamic range in metabolomics experiments by automatic correction of peaks exceeding the detection limit.
Lisec, J., Hoffmann, F., Schmitt, C. and Jaeger, C.
Analytical Chemistry 88 (15): 7487-7492. 2 August 2016

Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice.
Lisewski, U., Koehncke, C., Wilck, N., Buschmeyer, B., Pieske, B. and Roepke, T.K.
FASEB Journal 30 (7): 2476-2489. July 2016

Targeting of the Plzf gene in the rat by transcription activator-like effector nuclease results in caudal regression syndrome in spontaneously hypertensive rats.
Liška, F., Peterková, R., Peterka, M., Landa, V., Zidek, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Křen, V., Starker, C.G., Voytas, D.F., Izsvák, Z. and Pravenec, M.
PLoS ONE 11 (10): e0164206. 11 October 2016

Bacterial antisense RNAs are mainly the product of transcriptional noise.
Llorens-Rico, V., Cano, J., Kamminga, T., Gil, R., Latorre, A., Chen, W.H., Bork, P., Glass, J.I., Serrano, L. and Lluch-Senar, M.
Science Advances 2 (3): e1501363. 4 March 2016

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D., Pahuja, A., Geers-Knörr, C., Scheibe, R., Nowak, M., Hamati, J., Köhncke, C., Purfürst, B., Kanashova, T., Schmidt, S., Glass, D.J., Morano, I., Heuser, A., Kraft, T., Bassel-Duby, R., Olson, E.N., Dittmar, G., Sommer, T. and Fielitz, J.
Journal of Cachexia Sarcopenia and Muscle 7 (2): 165-180. May 2016

Minichromosome maintenance complex is a critical node in the miR-183 signaling network of MYCN-amplified neuroblastoma cells.
Lodrini, M., Poschmann, G., Schmidt, V., Wünschel, J., Dreidax, D., Witt, O., Höfer, T., Meyer, H.E., Stühler, K., Eggert, A. and Deubzer, H.E.
Journal of Proteome Research 15 (7): 2178-2186. 1 July 2016

Identification of novel genetic causes of Rett syndrome-like phenotypes.
Lopes, F., Barbosa, M., Ameur, A., Soares, G., de Sá, J., Dias, A.I., Oliveira, G., Cabral, P., Temudo, T., Calado, E., Cruz, I.F., Vieira, J.P., Oliveira, R., Esteves, S., Sauer, S., Jonasson, I., Syvänen, A.C., Gyllensten, U., Pinto, D. and Maciel, P.
Journal of Medical Genetics 53 (3): 190-199. March 2016

Aging vs. rejuvenation: reprogramming to iPSCs does not turn back the clock for somatic mitochondrial DNA mutations.
Lorenz, C. and Prigione, A.
Stem Cell Investigation 3 : 43. September 2016

Different promoter affinities account for specificity in MYC-dependent gene regulation.
Lorenzin, F., Benary, U., Baluapuri, A., Walz, S., Jung, L.A., von Eyss, B., Kisker, C., Wolf, J., Eilers, M. and Wolf, E.
eLife 5 : e15161. 27 July 2016

Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients.
Lu, H., Busch, J., Jung, M., Rabenhorst, S., Ralla, B., Kilic, E., Mergemeier, S., Budach, N., Fendler, A. and Jung, K.
Clinica Chimica Acta 452 : 109-119. 15 January 2016

In vivo and in vitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity.
Luchtman, D., Gollan, R., Ellwardt, E., Birkenstock, J., Robohm, K., Siffrin, V. and Zipp, F.
Journal of Neurochemistry 136 (5): 971-980. March 2016

Einfluss genetischer Varianten auf die humane Erythropoese [Influence of genetic variants on human erythropoiesis].
Ludwig, L.S.
BIOspektrum 22 (7): 768-769. November 2016

Emerging cellular and gene therapies for congenital anemias.
Ludwig, L.S., Khajuria, R.K. and Sankaran, V.G.
American Journal of Medical Genetics C 172C (4): 332-348. 12 December 2016

Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers.
Lueck, S.C., Russ, A.C., Botzenhardt, U., Schlenk, R.F., Zobel, K., Deshayes, K., Vucic, D., Döhner, H., Döhner, K., Fulda, S. and Bullinger, L.
Oncotarget 7 (31): 49539-49551. 2 August 2016

An osteoarthritis triple play.
Luft, F.C.
Journal of Molecular Medicine 94 (7): 735-737. July 2016

ATP-ADP translocase and effects on ischemic heart.
Luft, F.C.
Journal of Molecular Medicine 94 (6): 609-611. June 2016

A visionary scientist selects clinicians for clinical research.
Luft, F.C.
Journal of Molecular Medicine 94 (4): 371-372. April 2016

Hypoxemia as a model for high altitude and cardiovascular risk reduction.
Luft, F.C.
Journal of Molecular Medicine 94 (3): 247-249. March 2016

Coming of age with maintained cardiovascular health.
Luft, F.C.
Journal of the American Society of Hypertension 10 (1): 16-21. January 2016

High-mobility group box 1 protein, angiotensins, ACE2, and target organ damage.
Luft, F.C.
Journal of Molecular Medicine 94 (1): 1-3. January 2016

Could licorice lick inflammasomes?
Luft, F.C.
Journal of Molecular Medicine 94 (12): 1309-1311. December 2016

Asian flushing presents opportunities for disease prevention.
Luft, F.C.
Journal of Molecular Medicine 94 (11): 1195-1197. November 2016

NFAT5 moves to Fat City.
Luft, F.C.
Journal of Molecular Medicine 94 (9): 967-969. September 2016

Risk factors: evolving epidemiology of sodium intake and CVD.
Luft, F.C.
Nature Reviews Cardiology 13 (8): 445-446. August 2016

11-β hydroxysteroid dehydrogenase-2 and salt-sensitive hypertension.
Luft, F.C.
Circulation 133 (14): 1335-1337. 5 April 2016

Efficient application of de novo RNA assemblers for proteomics informed by transcriptomics.
Luge, T., Fischer, C. and Sauer, S.
Journal of Proteome Research 15 (10): 3938-3943. 7 October 2016

Generating sample-specific databases for mass spectrometry-based proteomic analysis by using RNA sequencing.
Luge, T. and Sauer, S.
Methods in Molecular Biology 1394 : 219-232. 2016

Breaking TADs: how alterations of chromatin domains result in disease.
Lupiáñez, D.G., Spielmann, M. and Mundlos, S.
Trends in Genetics 32 (4): 225-237. April 2016

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A novel splicing mutation in the IQSEC2 gene that modulates the phenotype severity in a family with intellectual disability.
Madrigal, I., Alvarez-Mora, M.I., Rosell, J., Rodríguez-Revenga, L., Karlberg, O., Sauer, S., Syvänen, A.C. and Mila, M.
European Journal of Human Genetics 24 (8): 1117-1123. August 2016

Chronic allergic pulmonary inflammation is aggravated in angiotensin-(1-7) Mas receptor knockout mice.
Magalhaes, G.S., Rodrigues-Machado, M.G., Motta-Santos, D., Alenina, N., Bader, M., Santos, R.A.S., Barcelos, L.S. and Campagnole-Santos, M.J.
American Journal of Physiology Lung Cellular and Molecular Physiology 311 (6): L1141-L1148. 12 December 2016

Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress.
Magarin, M., Pohl, T., Lill, A., Schulz, H., Blaschke, F., Heuser, A., Thierfelder, L., Donath, S. and Drenckhahn, J.D.
Journal of Molecular and Cellular Cardiology 97 : 1-14. August 2016

Transcriptional profiling of regenerating embryonic mouse hearts.
Magarin, M., Schulz, H., Thierfelder, L. and Drenckhahn, J.D.
Genomics Data 9 : 145-147. September 2016

Nuclear translocation of the cardiac L-type calcium channel C-terminus is regulated by sex and 17β-estradiol.
Mahmoodzadeh, S., Haase, H., Sporbert, A., Rharass, T., Panáková, D. and Morano, I.
Journal of Molecular and Cellular Cardiology 97 : 226-234. August 2016

Effects of the lercanidipine-enalapril combination vs. the corresponding monotherapies on home blood pressure in hypertension: evidence from a large database.
Mancia, G., Omboni, S., Chazova, I., Coca, A., Girerd, X., Haller, H., Parati, G., Pauletto, P., Pupek-Musialik, D. and Svyshchenko, Y.
Journal of Hypertension 34 (1): 139-148. January 2016

Separating sparse signals from correlated noise in binary classification.
Mandt, S., Wenzel, F., Nakajima, S., Lippert, C. and Kloft, M.
In: 2016 UAI Workshop on Causation: Foundation to Application, UAI-CFA, 29 June 2016, Jersey City, United States. 2016

Human engineered heart tissue: analysis of contractile force.
Mannhardt, I., Breckwoldt, K., Letuffe-Brenière, D., Schaaf, S., Schulz, H., Neuber, C., Benzin, A., Werner, T., Eder, A., Schulze, T., Klampe, B., Christ, T., Hirt, M.N., Huebner, N., Moretti, A., Eschenhagen, T. and Hansen, A.
Stem Cell Reports 7 (1): 29-42. 12 July 2016

Medical treatment of stable angina: a tailored therapeutic approach.
Manolis, A.J., Poulimenos, L.E., Ambrosio, G., Kallistratos, M.S., Lopez-Sendon, J., Dechend, R., Mancia, G. and Camm, A.J.
International Journal of Cardiology 220 : 445-453. 1 October 2016

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungstroem, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C.M., Couronne, L., Lenze, D., Baldus, C.D., Bastard, C., Okosun, J., Fitzgibbon, J., Doerken, B., Drexler, H.G., Roos-Weil, D., Schmitt, C.A., Munch-Petersen, H.D., Zenz, T., Hansmann, M.L., Strefford, J.C., Enblad, G., Bernard, O.A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Gronbaek, K., Lopez-Guillermo, A., Ogawa, S., Kueppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R.M., Ott, G., Vassilakopoulos, T.P., Hummel, M., Rosenquist, R. and Damm, F.
Blood 128 (23): 2666-2670. 15 December 2016

A complex water network contributes to high-affinity binding in an antibody-antigen interface.
Marino, S.F., Olal, D. and Daumke, O.
Data in Brief 6 : 394-397. March 2016

Role of cystathionine gamma-lyase in immediate renal impairment and inflammatory response in acute ischemic kidney injury.
Markó, L., Szijártó, I.A., Filipovic, M.R., Kaßmann, M., Balogh, A., Park, J.K., Przybyl, L., N'diaye, G., Krämer, S., Anders, J., Ishii, I., Müller, D.N. and Gollasch, M.
Scientific Reports 6 : 27517. 8 June 2016

Tubular epithelial NF-κB activity regulates ischemic AKI.
Markó, L., Vigolo, E., Hinze, C., Park, J.K., Roël, G., Balogh, A., Choi, M., Wübken, A., Cording, J., Blasig, I.E., Luft, F.C., Scheidereit, C., Schmidt-Ott, K.M., Schmidt-Ullrich, R. and Müller, D.N.
Journal of the American Society of Nephrology 27 (9): 2658-2669. September 2016

Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study.
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Lancet Neurology 15 (6): 574-584. May 2016

Microglia development follows a stepwise program to regulate brain homeostasis.
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Science 353 (6301): aad8670. 19 August 2016

Hodgkin lymphoma: pathology and biology.
Mathas, S., Hartmann, S. and Küppers, R.
Seminars in Hematology 53 (3): 139-147. July 2016

Weight loss partially restores glucose-driven betatrophin response in humans.
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Journal of Clinical Endocrinology and Metabolism 101 (11): 4014-4020. November 2016

An integer programming framework for inferring disease complexes from network data.
Mazza, A., Klockmeier, K., Wanker, E. and Sharan, R.
Bioinformatics 32 (12): i271-i277. 15 June 2016

The activation of OR51E1 causes growth suppression of human prostate cancer cells.
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Oncotarget 7 (30): 48231-48249. 26 July 2016

New technologies for DNA analysis - a review of the READNA project.
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New Biotechnology 33 (3): 311-330. 25 May 2016

Kinetic analysis of protein stability reveals age-dependent degradation.
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Cell 167 (3): 803-815. 20 October 2016

Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism.
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Neurobiology of Disease 89 : 112-125. May 2016

Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA.
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OncoImmunology 5 (5): e1138199. 18 February 2016

Omentin-1 and risk of myocardial infarction and stroke: results from the EPIC-Potsdam cohort study.
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Atherosclerosis 251 : 415-421. August 2016

Proteogenomics connects somatic mutations to signalling in breast cancer.
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Nature 534 (7605): 55-62. 2 June 2016

Specific metabolic markers are associated with future waist-gaining phenotype in women.
Merz, B., Nöthlings, U., Wahl, S., Haftenberger, M., Schienkiewitz, A., Adamski, J., Suhre, K., Wang-Sattler, R., Grallert, H., Thorand, B., Pischon, T., Bachlechner, U., Floegel, A., Peters, A. and Boeing, H.
PLoS ONE 11 (6): e0157733. 20 June 2016