A
Impaired human hematopoiesis due to a cryptic intronic splicing mutation.
Abdulhay, N.J., Fiorini, C., Verboon, J.M., Ludwig, L.S., Ulirsch, J.C., Zieger, B., Lareau, C.A., Mi, X., Roy, A., Obeng, E.A., Erlacher, M., Gupta, N., Gabriel, S.B., Ebert, B.L., Niemeyer, C.M., Khoriaty, R.N., Ancliff, P., Gazda, H.T., Wlodarski, M.W. and Sankaran, V.G.
Journal of Experimental Medicine 216
(5): 1050-1060.
6 May 2019
Critical role for piccolo in synaptic vesicle retrieval.
Ackermann, F., Schink, K.O., Bruns, C., Izsvák, Z., Hamra, F.K., Rosenmund, C. and Garner, C.C.
eLife 8
: e46629.
10 May 2019
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.
Ackermann, T., Hartleben, G., Müller, C., Mastrobuoni, G., Groth, M., Sterken, B.A., Zaini, M.A., Youssef, S.A., Zuidhof, H.R., Krauss, S.R., Kortman, G., de Haan, G., de Bruin, A., Wang, Z.Q., Platzer, M., Kempa, S. and Calkhoven, C.F.
Communications Biology 2
: 208.
14 June 2019
Development of robust 17(R),18(S)-epoxyeicosatetraenoic acid (17,18-EEQ) analogues as potential clinical antiarrhythmic agents.
Adebesin, A.M., Wesser, T., Vijaykumar, J., Konkel, A., Paudyal, M., Lossie, J., Zhu, C., Westphal, C., Puli, N., Fischer, R., Schunck, W.H. and Falck, J.
Journal of Medicinal Chemistry 62
(22): 10124-10143.
27 November 2019
A novel non-invasive method to detect RELM beta transcript in gut barrier related changes during a gastrointestinal nematode infection.
Ahmed, N., Heitlinger, E., Affinass, N., Kühl, A.A., Xenophontos, N., Jarquin, V.H., Jost, J., Steinfelder, S. and Hartmann, S.
Frontiers in Immunology 10
: 445.
March 2019
Lifestyle interventions in Muslim patients with metabolic syndrome: a feasibility study.
Aktas, M.F., Mähler, A., Hamm, M., Perger, G., Simon, F., Westenhöfer, J., Luft, F.C. and Boschmann, M.
European Journal of Clinical Nutrition 73
(5): 805-808.
May 2019
RIKADA study reveals risk factors in pediatric primary cardiomyopathy.
Al-Wakeel-Marquard, N., Degener, F., Herbst, C., Kühnisch, J., Dartsch, J., Schmitt, B., Kuehne, T., Messroghli, D., Berger, F. and Klaassen, S.
Journal of the American Heart Association 8
(15): e012531.
6 August 2019
Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview.
Alberto, M., Brandl, A., Garg, P.K., Gül-Klein, S., Dahlmann, M., Stein, U. and Rau, B.
Clinical and Experimental Metastasis 36
(1): 1-14.
February 2019
Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy.
Albrecht, S., Elpelt, A., Kasim, C., Reble, C., Mundhenk, L., Pischon, H., Hedtrich, S., Witzel, C., Lademann, J., Zastrow, L., Beckers, I. and Meinke, M.C.
Free Radical Biology and Medicine 131
: 299-308.
1 February 2019
Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids.
Alcala, N., Leblay, N., Gabriel, A.A.G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A.S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T.M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, V., Altmuller, J., Le Calvez-Kelm, F., Durand, G., Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A.C., Soltermann, A., Clement, J.H., Saenger, J., Field, J.K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P.A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J.M., Hofman, V., Hofman, P., Brustugun, O.T., Lund-Iversen, M., Thomas de Montpreville, V., Muscarella, L.A., Graziano, P., Popper, H., Stojsic, J., Deleuze, J.F., Herceg, Z., Viari, A., Nuernberg, P., Pelosi, G., Dingemans, A.M.C., Milione, M., Roz, L., Brcic, L., Volante, M., Papotti, M.G., Caux, C., Sandoval, J., Hernandez-Vargas, H., Brambilla, E., Speel, E.J.M., Girard, N., Lantuejoul, S., McKay, J.D., Foll, M. and Fernandez-Cuesta, L.
Nature Communications 10
(1): 3407.
20 August 2019
Fatty acid-binding protein 4 and risk of type 2 diabetes, myocardial infarction and stroke: a prospective cohort study.
Aleksandrova, K., Drogan, D., Weikert, C., Schulze, M.B., Fritsche, A., Boeing, H. and Pischon, T.
Journal of Clinical Endocrinology and Metabolism 104
(12): 5991-6002.
December 2019
Biological determinants of physical activity across the life course: a "Determinants of Diet and Physical Activity" (DEDIPAC) umbrella systematic literature review.
Aleksovska, K., Puggina, A., Giraldi, L., Buck, C., Burns, C., Cardon, G., Carlin, A., Chantal, S., Ciarapica, D., Colotto, M., Condello, G., Coppinger, T., Cortis, C., D'Haese, S., De Craemer, M., Di Blasio, A., Hansen, S., Iacoviello, L., Issartel, J., Izzicupo, P., Jaeschke, L., Kanning, M., Kennedy, A., Ling, F., Luzak, A., Napolitano, G., Nazare, J.A., Perchoux, C., Pischon, T., Polito, A., Sannella, A., Schulz, H., Sohun, R., Steinbrecher, A., Schlicht, W., Ricciardi, W., MacDonncha, C., Capranica, L. and Boccia, S.
Sports Medicine - Open 5
(1): 2.
8 January 2019
ACE2 in brain physiology and pathophysiology: evidence from transgenic animal models.
Alenina, N. and Bader, M.
Neurochemical Research 44
(6): 1323-1329.
June 2019
Genetic models.
Alenina, N. and Bader, M.
In:
Angiotensin-(1-7) : a comprehensive review.
Springer, Cham, 35-51.
ISBN 978-3-030-22695-4
2019
Polycystin-1 assembles with Kv channels to govern cardiomyocyte repolarization and contractility.
Altamirano, F., Schiattarella, G.G., French, K.M., Kim, S.Y., Engelberger, F., Kyrychenko, S., Villalobos, E., Tong, D., Schneider, J.W., Ramirez-Sarmiento, C.A., Lavandero, S., Gillette, T.G. and Hill, J.A.
Circulation 140
(11): 921-936.
10 September 2019
Assessment of bones deficient in fibrillin-1 microfibrils reveals pronounced sex differences.
Altinbas, L., Bormann, N., Lehmann, D., Jeuthe, S., Wulsten, D., Kornak, U., Robinson, P.N., Wildemann, B. and Kararigas, G.
International Journal of Molecular Sciences 20
(23): 6059.
1 December 2019
StaBle angina: peRceptIon of neeDs, quality of life and manaGemEnt of patients (BRIDGE study) - a multinational European physician survey.
Ambrosio, G., Collins, P., Dechend, R., Lopez-Sendon, J., Manolis, A.J. and Camm, A.J.
Angiology 70
(5): 397-406.
1 May 2019
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing.
Andersch, L., Radke, J., Klaus, A., Schwiebert, S., Winkler, A., Schumann, E., Grunewald, L., Zirngibl, F., Flemmig, C., Jensen, M.C., Rossig, C., Joussen, A., Henssen, A., Eggert, A., Schulte, J.H. and Künkele, A.
BMC Cancer 19
(1): 895.
9 September 2019
Endothelial metabolism - more complex (III) than previously thought.
Andrade, J. and Potente, M.
Nature Metabolism 1
(1): 14-15.
January 2019
Analysis of NTRK expression in gastric and esophageal adenocarcinoma (AGE) with pan-TRK immunohistochemistry.
Arnold, A., Daum, S., von Winterfeld, M., Berg, E., Hummel, M., Horst, D., Rau, B., Stein, U. and Treese, C.
Pathology Research and Practice 215
(11): 152662.
November 2019
Regulation of influenza a virus mRNA splicing by CLK1.
Artarini, A., Meyer, M., Shin, Y.J., Huber, K., Hilz, N., Bracher, F., Eros, D., Orfi, L., Keri, G., Goedert, S., Neuenschwander, M., von Kries, J., Domovich-Eisenberg, Y., Dekel, N., Szabadkai, I., Lebendiker, M., Horváth, Z., Danieli, T., Livnah, O., Moncorgé, O., Frise, R., Barclay, W., Meyer, T.F. and Karlas, A.
Antiviral Research 168
: 187-196.
August 2019
Saffron: The golden spice with therapeutic properties on digestive diseases.
Ashktorab, H., Soleimani, A., Singh, G., Amr, A., Tabtabaei, S., Latella, G., Stein, U., Akhondzadeh, S., Solanki, N., Gondré-Lewis, M.C., Habtezion, A. and Brim, H.
Nutrients 11
(5): 943.
26 April 2019
B
Vision and vision-related measures in progressive multiple sclerosis.
Backner, Y., Petrou, P., Glick-Shames, H., Raz, N., Zimmermann, H., Jost, R., Scheel, M., Paul, F., Karussis, D. and Levin, N.
Frontiers in Neurology 10
: 455.
May 2019
Serotonylation: serotonin signaling and epigenetics.
Bader, M.
Frontiers in Molecular Neuroscience 12
: 288.
21 November 2019
hnRNP-K targets open chromatin in mouse embryonic stem cells in concert with multiple regulators.
Bakhmet, E.I., Nazarov, I.B., Gazizova, A.R., Vorobyeva, N.E., Kuzmin, A.A., Gordeev, M.N., Sinenko, S.A., Aksenov, N. D., Artamonova, T.O., Khodorkovskii, M.A., Alenina, N., Onichtchouk, D., Wu, G., Schöler, H.R. and Tomilin, A.N.
Stem Cells 37
(8): 1018-1029.
August 2019
Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis; a longitudinal OCT study.
Balk, L.J., Coric, D., Knier, B., Zimmermann, H.G., Behbehani, R., Alroughani, R., Martinez-Lapiscina, E.H., Brandt, A.U., Sánchez-Dalmau, B., Vidal-Jordana, A., Albrecht, P., Koska, V., Havla, J., Pisa, M., Nolan, R.C., Leocani, L., Paul, F., Aktas, O., Montalban, X., Balcer, L.J., Villoslada, P., Outteryck, O., Korn, T. and Petzold, A.
Multiple Sclerosis Journal Experimental Translational and Clinical 5
(3): 2055217319871582.
1 July 2019
Small molecules for modulating the localisation of the water channel aquaporin-2-disease relevance and perspectives for targeting local cAMP signalling.
Baltzer, S. and Klussmann, E.
Naunyn-Schmiedeberg's Archives of Pharmacology 392
(9): 1049-1064.
September 2019
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembling cofactors ASPL/PUX1.
Banchenko, S., Arumughan, A., Petrović, S., Schwefel, D., Wanker, E.E., Roske, Y. and Heinemann, U.
Structure 27
(12): 1830-1841.
3 December 2019
Linoleic acid metabolite DiHOME decreases post-ischemic cardiac recovery in murine hearts.
Bannehr, M., Löhr, L., Gelep, J., Haverkamp, W., Schunck, W.H., Gollasch, M. and Wutzler, A.
Cardiovascular Toxicology 19
(4): 365-371.
August 2019
In contrast to Western diet, a plant-based, high-fat, low-sugar diet does not exacerbate retinal endothelial injury in streptozotocin-induced diabetes.
Barakat, A., Nakao, S., Zandi, S., Sun, D., Schmidt-Ullrich, R., Hayes, K.C. and Hafezi-Moghadam, A.
FASEB Journal 33
(9): 10327-10338.
September 2019
Short-chain fatty acid propionate protects from hypertensive cardiovascular damage.
Bartolomaeus, H., Balogh, A., Yakoub, M., Homann, S., Markó, L., Höges, S., Tsvetkov, D., Krannich, A., Wundersitz, S., Avery, E.G., Haase, N., Kräker, K., Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J., Kempa, S., Gollasch, M., Zhumadilov, Z., Kozhakhmetov, S., Kushugulova, A., Eckardt, K.U., Dechend, R., Rump, L.C., Forslund, S.K., Müller, D.N., Stegbauer, J. and Wilck, N.
Circulation 139
(11): 1407-1421.
12 March 2019
Precarious symbiosis between host and microbiome in cardiovascular health.
Bartolomaeus, H., Markó, L., Wilck, N., Luft, F.C., Forslund, S.K. and Muller, D.N.
Hypertension 73
(5): 926-935.
May 2019
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.
Basheer, F., Giotopoulos, G., Meduri, E., Yun, H., Mazan, M., Sasca, D., Gallipoli, P., Marando, L., Gozdecka, M., Asby, R., Sheppard, O., Dudek, M., Bullinger, L., Döhner, H., Dillon, R., Freeman, S., Ottmann, O., Burnett, A., Russell, N., Papaemmanuil, E., Hills, R., Campbell, P., Vassiliou, G.S.. and Huntly, B.J.P.
Journal of Experimental Medicine 216
(4): 966-981.
1 April 2019
All-in-one confocal and widefield fluorescence microscope to investigate membrane receptor dynamics.
Bathe-Peters, M., Gmach, P., Annibale, P. and Lohse, M.J.
In: Imaging and Applied Optics Congress 2019 (COSI, IS, MATH, pcAOP), 24-27 Jun 2019, Munich, Germany.
2019
Gain-of-function mutations in KCNN3 encoding the small-conductance Ca(2+)-activated K(+) channel SK3 cause Zimmermann-Laband syndrome.
Bauer, C.K., Schneeberger, P.E., Kortüm, F., Altmüller, J., Santos-Simarro, F., Baker, L., Keller-Ramey, J., White, S.M., Campeau, P.M., Gripp, K.W. and Kutsche, K.
American Journal of Human Genetics 104
(6): 1139-1157.
6 June 2019
Analysis of correlation-based biomolecular networks from different omics data by fitting stochastic block models.
Baum, K., Rajapakse, J.C. and Azuaje, F.
F1000Research 8
: 465.
27 August 2019
Of gene expression and cell division time: a mathematical framework for advanced differential gene expression and data analysis.
Baum, K., Schuchhardt, J., Wolf, J. and Busse, D.
Cell Systems 9
(6): 569-579.
18 December 2019
Association between physical activity and risk of hepatobiliary cancers: a multinational cohort study.
Baumeister, S.E., Schlesinger, S., Aleksandrova, K., Jochem, C., Jenab, M., Gunter, M.J., Overvad, K., Tjønneland, A., Boutron-Ruault, M.C., Carbonnel, F., Fournier, A., Kühn, T., Kaaks, R., Pischon, T., Boeing, H., Trichopoulou, A., Bamia, C., La Vecchia, C., Masala, G., Panico, S., Fasanelli, F., Tumino, R., Grioni, S., de Mesquita, B.B., Vermeulen, R., May, A.M., Borch, K.B., Oyeyemi, S.O., Ardanaz, E., Rodríguez-Barranco, M., López, M.D.C., Felez-Nobrega, M., Sonestedt, E., Ohlsson, B., Hemmingsson, O., Werner, M., Perez-Cornago, A., Ferrari, P., Stepien, M., Freisling, H., Tsilidis, K.K., Ward, H., Riboli, E., Weiderpass, E. and Leitzmann, M.F.
Journal of Hepatology 70
(5): 885-892.
May 2019
Simultaneous high-resolution cardiac T(1) mapping and cine imaging using model-based iterative image reconstruction.
Becker, K.M., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C.
Magnetic Resonance in Medicine 81
(2): 1080-1091.
February 2019
Controlling nuclear NF-κB dynamics by β-TrCP-insights from a computational model.
Benary, U. and Wolf, J.
Biomedicines 7
(2): 40.
27 May 2019
Modelling the DNA topology: the effect of the loop bending on G-quadruplex stability.
Bergues-Pupo, A.E., Falo, F. and Fiasconaro, A.
Journal of Statistical Mechanics: Theory and Experiment 2019
(9): 094004.
2 September 2019
Does divergent binding pocket closure drive ligand bias for class A GPCRs?
Bermudez, M. and Bock, A.
Trends in Pharmacological Sciences 40
(4): 236-239.
April 2019
Tight junction proteins at the blood-brain barrier: far more than claudin-5.
Berndt, P., Winkler, L., Cording, J., Breitkreuz-Korff, O., Rex, A., Dithmer, S., Rausch, V., Blasig, R., Richter, M., Sporbert, A., Wolburg, H., Blasig, I.E. and Haseloff, R.F.
Cellular and Molecular Life Sciences 76
(10): 1987-2002.
May 2019
Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Bhaskara, R.M., Grumati, P., Garcia-Pardo, J., Kalayil, S., Covarrubias-Pinto, A., Chen, W., Kudryashev, M., Dikic, I. and Hummer, G.
Nature Communications 10
(1): 2370.
30 May 2019
Modeling single-molecule conformations of the HoxD region in mouse embryonic stem and cortical neuronal cells.
Bianco, S., Annunziatella, C., Andrey, G., Chiariello, A.M., Esposito, A., Fiorillo, L., Prisco, A., Conte, M., Campanile, R. and Nicodemi, M.
Cell Reports 28
(6): 1574-1583.
6 August 2019
Editorial overview: Genome architecture and expression.
Bickmore, W. and Pombo, A.
Current Opinion in Genetics & Development 55
: iii-iv.
April 2019
Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.
Binger, K.J., Neukam, M., Tattikota, S.G., Qadri, F., Puchkov, D., Willmes, D.M., Wurmsee, S., Geisberger, S., Dechend, R., Raile, K., Kurth, T., Nguyen, G., Poy, M.N., Solimena, M., Muller, D.N. and Birkenfeld, A.L.
Proceedings of the National Academy of Sciences of the United States of America 116
(40): 19983-19988.
1 October 2019
Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein.
Birol, M., Wojcik, S.P., Miranker, A.D. and Rhoades, E.
PLoS Biology 17
(6): e3000318.
18 June 2019
Aldosterone, salt, and potassium intakes as predictors of pregnancy outcome, including preeclampsia.
Birukov, A., Andersen, L.B., Herse, F., Rakova, N., Kitlen, G., Kyhl, H.B., Golic, M., Haase, N., Kräker, K., Müller, D.N., Jørgensen, J.S., Andersen, M.S., Dechend, R. and Jensen, B.L.
Hypertension 74
(2): 391-398.
August 2019
Regulatory antibodies against GPCR in women ten years after early-onset preeclampsia.
Birukov, A., Muijsers, H.E.C., Heidecke, H., Drost, J.T., Cunnigham, M.W., Kraker, K., Haase, N., Frolova, A., Müller, D.N., Herse, F., Maas, A.H.E.M. and Dechend, R.
Frontiers in Bioscience 24
: 1462-1476.
1 June 2019
A clonal expression biomarker associates with lung cancer mortality.
Biswas, D., Birkbak, N.J., Rosenthal, R., Hiley, C.T., Lim, E.L., Papp, K., Boeing, S., Krzystanek, M., Djureinovic, D., La Fleur, L., Greco, M., Döme, B., Fillinger, J., Brunnström, H., Wu, Y., Moore, D.A., Skrzypski, M., Abbosh, C., Litchfield, K., Al Bakir, M., Watkins, T.B.K., Veeriah, S., Wilson, G.A., Jamal-Hanjani, M., Moldvay, J., Botling, J., Chinnaiyan, A.M., Micke, P., Hackshaw, A., Bartek, J., Csabai, I., Szallasi, Z., Herrero, J., McGranahan, N. and Swanton, C.
Nature Medicine 25
(10): 1540-1548.
October 2019
Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose : aktueller Stand und Empfehlungen in Deutschland [Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : current status and recommendations in Germany].
Bittner, S., Engel, S., Lange, C., Weber, M.S., Haghikia, A., Luessi, F., Korn, T., Klotz, L., Bayas, A., Paul, F., Heesen, C., Stangel, M., Wildemann, B., Bergh, F.T., Tackenberg, B., Trebst, C., Warnke, C., Linker, R., Kerschensteiner, M., Zettl, U., Tumani, H., Brück, W., Meuth, S.G., Kümpfel, T., Hemmer, B., Wiendl, H., Gold, R. and Zipp, F.
Nervenarzt 90
(12): 1245-1253.
December 2019
Identification and ranking of recurrent neo-epitopes in cancer.
Blanc, E., Holtgrewe, M., Dhamodaran, A., Messerschmidt, C., Willimsky, G., Blankenstein, T. and Beule, D.
BMC Medical Genomics 12
: 171.
27 November 2019
Subclinical myocardial injury in patients with Facioscapulohumeral muscular dystrophy 1 and preserved ejection fraction - assessment by cardiovascular magnetic resonance.
Blaszczyk, E., Grieben, U., von Knobelsdorff-Brenkenhoff, F., Kellman, P., Schmacht, L., Funk, S., Spuler, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 21
(1): 25.
29 April 2019
Pregnancy galectinology: insights into a complex network of glycan binding proteins.
Blois, S.M., Dveksler, G., Vasta, G.R., Freitag, N., Blanchard, V. and Barrientos, G.
Frontiers in Immunology 10
: 1166.
May 2019
Chiral lipidomics of monoepoxy and monohydroxy metabolites derived from long-chain polyunsaturated fatty acids.
Blum, M., Dogan, I., Karber, M., Rothe, M. and Schunck, W.H.
Journal of Lipid Research 60
(1): 135-148.
January 2019
getITD for FLT3-ITD-based MRD monitoring in AML.
Blätte, T.J., Schmalbrock, L.K., Skambraks, S., Lux, S., Cocciardi, S., Dolnik, A., Döhner, H., Döhner, K. and Bullinger, L.
Leukemia 33
(10): 2535-2539.
October 2019
Identification and regulation of the long non-coding RNA Heat2 in heart failure.
Boeckel, J.N., Perret, M.F., Glaser, S.F., Seeger, T., Heumüller, A.W., Chen, W., John, D., Kokot, K.E., Katus, H.A., Haas, J., Lackner, M.K., Kayvanpour, E., Grabe, N., Dieterich, C., von Haehling, S., Ebner, N., Hünecke, S., Leuschner, F., Fichtlscherer, S., Meder, B., Zeiher, A.M., Dimmeler, S. and Keller, T.
Journal of Molecular and Cellular Cardiology 126
: 13-22.
January 2019
The anti-amyloid compound DO1 decreases plaque pathology and neuroinflammation-related expression changes in 5xFAD transgenic mice.
Boeddrich, A., Babila, J.T., Wiglenda, T., Diez, L., Jacob, M., Nietfeld, W., Huska, M.R., Haenig, C., Groenke, N., Buntru, A., Blanc, E., Meier, J.C., Vannoni, E., Erck, C., Friedrich, B., Martens, H., Neuendorf, N., Schnoegl, S., Wolfer, D.P., Loos, M., Beule, D., Andrade-Navarro, M.A. and Wanker, E.E.
Cell Chemical Biology 26
(1): 109-120.
17 January 2019
Cardiorenal sodium MRI at 7.0 Tesla using a 4/4 channel (1)H/(23)Na radiofrequency antenna array.
Boehmert, L., Kuehne, A., Waiczies, H., Wenz, D., Eigentler, T.W., Funk, S., von Knobelsdorff-Brenkenhoff, F., Schulz-Menger, J., Nagel, A.M., Seeliger, E. and Niendorf, T.
Magnetic Resonance in Medicine 82
(6): 2343-2356.
December 2019
The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant.
Bogdanow, B., Wang, X., Eichelbaum, K., Sadewasser, A., Husic, I., Paki, K., Budt, M., Hergeselle, M., Vetter, B., Hou, J., Chen, W., Wiebusch, L., Meyer, I.M., Wolff, T. and Selbach, M.
Nature Communications 10
(1): 5518.
4 December 2019
New targeted agents in acute myeloid leukemia: new hope on the rise.
Bohl, S.R., Bullinger, L. and Rücker, F.G.
International Journal of Molecular Sciences 20
(8)
23 April 2019
Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage.
Boltze, J., Ferrara, F., Hainsworth, A.H., Bridges, L.R., Zille, M., Lobsien, D., Barthel, H., McLeod, D.D., Gräßer, F., Pietsch, S., Schatzl, A.K., Dreyer, A.Y. and Nitzsche, B.
Journal of Cerebral Blood Flow and Metabolism 39
(12): 2521-2535.
1 December 2019
WiPP: workflow for improved peak picking for gas chromatography-mass spectrometry (GC-MS) data.
Borgsmüller, N., Gloaguen, Y., Opialla, T., Blanc, E., Sicard, E., Royer, A.L., Le Bizec, B., Durand, S., Migné, C., Pétéra, M., Pujos-Guillot, E., Giacomoni, F., Guitton, Y., Beule, D. and Kirwan, J.
Metabolites 9
(9): 171.
21 August 2019
Somatostatin 2 receptors in the spinal cord tonically restrain thermogenic, cardiac and other sympathetic outflows.
Bowman, B.R., Bokiniec, P., McMullan, S., Goodchild, A.K. and Burke, P.G.R.
Frontiers in Neuroscience 13
: 121.
February 2019
Light-microscopy methods in C. elegans research.
Breimann, L., Preusser, F. and Preibisch, S.
Current Opinion in Systems Biology 13
: 82-92.
February 2019
EU-OPENSCREEN: a novel collaborative approach to facilitate chemical biology.
Brennecke, P., Rasina, D., Aubi, O., Herzog, K., Landskron, J., Cautain, B., Vicente, F., Quintana, J., Mestres, J., Stechmann, B., Ellinger, B., Brea, J., Kolanowski, J.L., Pilarski, R., Orzaez, M., Pineda-Lucena, A., Laraia, L., Nami, F., Zielenkiewicz, P., Paruch, K., Hansen, E., von Kries, J.P., Neuenschwander, M., Specker, E., Bartunek, P., Simova, S., Leśnikowski, Z., Krauss, S., Lehtiö, L., Bilitewski, U., Brönstrup, M., Taskén, K., Jirgensons, A., Lickert, H., Clausen, M.H., Andersen, J.H., Vicent, M.J., Genilloud, O., Martinez, A., Nazaré, M., Fecke, W. and Gribbon, P.
SLAS Discovery 24
(3): 398-413.
1 March 2019
Microbiome determinants and physiological effects of the benzoate-hippurate microbial-host co-metabolic pathway.
Brial, F., Chilloux, J., Nielsen, T., Vieira-Silva, S., Falony, G., Hoyles, L., Neves, A.L., Rodriguez-Martinez, A., Mouawad, G.I., Pons, N., Forslund, S., Le Chatelier, E., Le Lay, A.M., Nicholson, J.K., Hansen, T., Clément, K., Bork, P., Ehrlich, S.D., Raes, J., Pedersen, O., Gauguier, D. and Dumas, M.E.
bioRxiv
: 2019.12.15.876672.
16 December 2019
Crowdfunded whole-genome sequencing of the celebrity cat Lil BUB identifies causal mutations for her osteopetrosis and polydactyly.
Bridavsky, M., Kuhl, H., Woodruf, A., Kornak, U., Timmermann, B., Mages, N., Lupiáñez, D.G., Symmons, O. and Ibrahim, D.M.
bioRxiv
: 556761.
22 February 2019
RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.
Brockmann, M.M., Maglione, M., Willmes, C.G., Stumpf, A., Bouazza, B.A., Velasquez, L.M., Grauel, M.K., Beed, P., Lehmann, M., Gimber, N., Schmoranzer, J., Sigrist, S.J., Rosenmund, C. and Schmitz, D.
eLife 8
: e43243.
19 September 2019
Time-resolved DNA release from an O-antigen specific Salmonella bacteriophage with a contractile tail.
Broeker, N.K., Roske, Y., Valleriani, A., Stephan, M.S., Andres, D., Koetz, J., Heinemann, U. and Barbirz, S.
Journal of Biological Chemistry 294
(31): 11751-11761.
2 August 2019
IDH2 inhibition: another piece to the puzzle.
Bullinger, L.
Blood 133
(7): 625-626.
14 February 2019
let-7 microRNAs regulate microglial function and suppress glioma growth through Toll-like receptor 7.
Buonfiglioli, A., Efe, I.E., Guneykaya, D., Ivanov, A., Huang, Y., Orlowski, E., Krüger, C., Deisz, R.A., Markovic, D., Flüh, C., Newman, A.G., Schneider, U.C., Beule, D., Wolf, S.A., Dzaye, O., Gutmann, D.H., Semtner, M., Kettenmann, H. and Lehnardt, S.
Cell Reports 29
(11): 3460-3471.
10 December 2019
Isolation and long-term cultivation of mouse alveolar macrophages.
Busch, C. J.-L., Favret, J., Geirsdóttir, L., Molawi, K. and Sieweke, M.H.
Bio-protocol 9
(14)
20 July 2019
Analysis of the CDK4/6 cell cycle pathway in leiomyosarcomas as a potential target for inhibition by palbociclib.
Böhm, M.J., Marienfeld, R., Jäger, D., Mellert, K., von Witzleben, A., Brüderlein, S., Wittau, M., von Baer, A., Schultheiss, M., Mayer-Steinacker, R., Rücker, F.G., Möller, P., Bullinger, L. and Barth, T.F.E.
Sarcoma 2019
: 3914232.
21 January 2019
Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis.
Böttcher, C., Fernández-Zapata, C., Schlickeiser, S., Kunkel, D., Schulz, A.R., Mei, H.E., Weidinger, C., Gieß, R.M., Asseyer, S., Siegmund, B., Paul, F., Ruprecht, K. and Priller, J.
Scientific Reports 9
(1): 19471.
19 December 2019
C
Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data.
Calviello, L., Sydow, D., Harnett, D. and Ohler, U.
bioRxiv
: 601468.
8 April 2019
Community-level responses to iron availability in open ocean plankton ecosystems.
Caputi, L., Carradec, Q., Eveillard, D., Kirilovsky, A., Pelletier, E., Pierella Karlusich, J.J., Rocha Jimenez Vieira, F., Villar, E., Chaffron, S., Malviya, S., Scalco, E., Acinas, S.G., Alberti, A., Aury, J.M., Benoiston, A.S., Bertrand, A., Biard, T., Bittner, L., Boccara, M., Brum, J.R., Brunet, C., Busseni, G., Carratalà, A., Claustre, H., Coelho, L.P., Colin, S., D'Aniello, S., Da Silva, C., Del Core, M., Doré, H., Gasparini, S., Kokoszka, F., Jamet, J.L., Lejeusne, C., Lepoivre, C., Lescot, M., Lima‐Mendez, G., Lombard, F., Lukeš, J., Maillet, N., Madoui, M.A., Martinez, E., Mazzocchi, M.G., Néou, M.B., Paz‐Yepes, J., Poulain, J., Ramondenc, S., Romagnan, J.B., Roux, S., Salvagio Manta, D., Sanges, R., Speich, S., Sprovieri, M., Sunagawa, S., Taillandier, V., Tanaka, A., Tirichine, L., Trottier, C., Uitz, J., Veluchamy, A., Veselá, J., Vincent, F., Yau, S., Kandels‐Lewis, S., Searson, S., Dimier, C., Picheral, M., Bork, P., Boss, E., Vargas, C., Follows, M.J., Grimsley, N., Guidi, L., Hingamp, P., Karsenti, E., Sordino, P., Stemmann, L., Sullivan, M.B., Tagliabue, A., Zingone, A., Garczarek, L., d'Ortenzio, F., Testor, P., Not, F., Ribera d'Alcalà, M., Wincker, P., Bowler, C. and Iudicone, D.
Global Biogeochemical Cycles 33
(3): 391-419.
March 2019
Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort.
Caputo, M., Horn, J., Karch, A., Akmatov, M.K., Becher, H., Braun, B., Brenner, H., Castell, S., Fischer, B., Giani, G., Günther, K., Hoffmann, B., Jöckel, K.H., Keil, T., Klüppelholz, B., Krist, L., Leitzmann, M.F., Lieb, W., Linseisen, J., Meisinger, C., Moebus, S., Obi, N., Pischon, T., Schipf, S., Schmidt, B., Sievers, C., Steinbrecher, A., Völzke, H. and Mikolajczyk, R.
BMC Infectious Diseases 19
(1): 99.
30 January 2019
Simultaneous SPECT/MR imaging with a SiPM-based preclinical insert.
Carminati, M., Baratelli, F.M., Massara, M., Occhipinti, M., Nagy, K., Nyitrai, Z., Czeller, M., Kühne, A., Niendorf, T., Valtorta, S., Belloli, S., Moresco, R.M., Savi, A., Iadanza, A., Falini, A., Politi, L.S., Cadioli, M. and Fiorini, C.
In: 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC), 10-17 Nov 2018, Sydney, NSW, Australia.
5 September 2019
Validation and performance assessment of a preclinical SiPM-based SPECT/MRI insert.
Carminati, M., Baratelli, F.M., Occhipinti, M., Erlandsson, K., Nagy, K., Nyitrai, Z., Czeller, M., Kühne, A., Niendorf, T., Valtorta, S., Belloli, S., Moresco, R.M., Savi, A., Iadanza, A., Falini, A., Politi, L.S., Cadioli, M., Hutton, B.F. and Fiorini, C.
IEEE Transactions on Radiation and Plasma Medical Sciences 3
(4): 483-490.
July 2019
Mesothelial-mesenchymal transitions in embryogenesis.
Carmona, R., Ariza, L., Cano, E., Jiménez-Navarro, M. and Muñoz-Chápuli, R.
Seminars in Cell & Developmental Biology 92
: 37-44.
August 2019
Nephropathy in hypertensive animals is linked to M2 macrophages and increased expression of the YM1/Chi3l3 protein.
Cavalcante, P.A.M., Alenina, N., Budu, A., Freitas-Lima, L.C., Alves-Silva, T., Agudelo, J.S.H., Qadri, F., Camara, N.O.S., Bader, M. and Araújo, R.C.
Mediators of Inflammation 2019
: 9086758.
10 July 2019
Integrative approaches in structural biology: a more complete picture from the combination of individual techniques.
Cerofolini, L., Fragai, M., Ravera, E., Diebolder, C.A., Renault, L. and Calderone, V.
Biomolecules 9
(8): 370.
14 August 2019
Postnatal Tshz3 deletion drives altered corticostriatal function and autism spectrum disorder-like behavior.
Chabbert, D., Caubit, X., Roubertoux, P.L., Carlier, M., Habermann, B., Jacq, B., Salin, P., Metwaly, M., Frahm, C., Fatmi, A., Garratt, A.N., Severac, D., Dubois, E., Kerkerian-Le Goff, L., Fasano, L. and Gubellini, P.
Biological Psychiatry 86
(4): 274-285.
15 August 2019
Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.
Chaimowicz, C., Ruffault, P.L., Chéret, C., Woehler, A., Zampieri, N., Fortin, G., Garratt, A.N. and Birchmeier, C.
Development 146
(17): dev174045.
6 September 2019
Multi-platform discovery of haplotype-resolved structural variation in human genomes.
Chaisson, M.J.P., Sanders, A.D., Zhao, X., Malhotra, A., Porubsky, D., Rausch, T., Gardner, E.J., Rodriguez, O.L., Guo, L., Collins, R.L., Fan, X., Wen, J., Handsaker, R.E., Fairley, S., Kronenberg, Z.N., Kong, X., Hormozdiari, F., Lee, D., Wenger, A.M., Hastie, A.R., Antaki, D., Anantharaman, T., Audano, P.A., Brand, H., Cantsilieris, S., Cao, H., Cerveira, E., Chen, C., Chen, X., Chin, C.S., Chong, Z., Chuang, N.T., Lambert, C.C., Church, D.M., Clarke, L., Farrell, A., Flores, J., Galeev, T., Gorkin, D.U., Gujral, M., Guryev, V., Heaton, W.H., Korlach, J., Kumar, S., Kwon, J.Y., Lam, E.T., Lee, J.E., Lee, J., Lee, W.P., Lee, S.P., Li, S., Marks, P., Viaud-Martinez, K., Meiers, S., Munson, K.M., Navarro, F.C.P., Nelson, B.J., Nodzak, C., Noor, A., Kyriazopoulou-Panagiotopoulou, S., Pang, A.W.C., Qiu, Y., Rosanio, G., Ryan, M., Stütz, A., Spierings, D.C.J., Ward, A., Welch, A.E., Xiao, M., Xu, W., Zhang, C., Zhu, Q., Zheng-Bradley, X., Lowy, E., Yakneen, S., McCarroll, S., Jun, G., Ding, L., Koh, C.L., Ren, B., Flicek, P., Chen, K., Gerstein, M.B., Kwok, P.Y., Lansdorp, P.M., Marth, G.T., Sebat, J., Shi, X., Bashir, A., Ye, K., Devine, S.E., Talkowski, M.E., Mills, R.E., Marschall, T., Korbel, J.O., Eichler, E.E. and Lee, C.
Nature Communications 10
(1): 1784.
16 April 2019
Comparing agent‐based delivery of DNA and PNA forced intercalation (FIT) probes for multicolor mRNA imaging.
Chamiolo, J., Fang, G.M., Hövelmann, F., Friedrich, D., Knoll, A., Loewer, A. and Seitz, O.
ChemBioChem 20
(4): 595-604.
15 February 2019
Molecular recording of mammalian embryogenesis.
Chan, M.M., Smith, Z.D., Grosswendt, S., Kretzmer, H., Norman, T.M., Adamson, B., Jost, M., Quinn, J.J., Yang, D., Jones, M.G., Khodaverdian, A., Yosef, N., Meissner, A. and Weissman, J.S.
Nature 570
(7759): 77-82.
6 June 2019
A cellular mechanism underlying enhanced capability for complex olfactory discrimination learning.
Chandra, N., Awasthi, R., Ozdogan, T., Johenning, F.W., Imbrosci, B., Morris, G., Schmitz, D. and Barkai, E.
eNeuro 6
(1): e0198-18.2019.
January 2019
Roles of long noncoding RNAs and circular RNAs in translation.
Chekulaeva, M. and Rajewsky, N.
Cold Spring Harbor Perspectives in Biology 11
(6): a032680.
3 June 2019
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.
Chemi, F., Rothwell, D.G., McGranahan, N., Gulati, S., Abbosh, C., Pearce, S.P., Zhou, C., Wilson, G.A., Jamal-Hanjani, M., Birkbak, N., Pierce, J., Kim, C.S., Ferdous, S., Burt, D.J., Slane-Tan, D., Gomes, F., Moore, D., Shah, R., Al Bakir, M., Hiley, C., Veeriah, S., Summers, Y., Crosbie, P., Ward, S., Mesquita, B., Dynowski, M., Biswas, D., Tugwood, J., Blackhall, F., Miller, C., Hackshaw, A., Brady, G., Swanton, C. and Dive, C.
Nature Medicine 25
(10): 1534-1539.
October 2019
Current and future treatment strategies for rhabdomyosarcoma.
Chen, C., Dorado-Garcia, H., Scheer, M. and Henssen, A.G.
Frontiers in Oncology 9
: 1458.
20 December 2019
WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.
Chen, H., Moreno-Moral, A., Pesce, F., Devapragash, N., Mancini, M., Heng, E.L., Rotival, M., Srivastava, P.K., Harmston, N., Shkura, K., Rackham, O.J.L., Yu, W.P., Sun, X.M., Tee, N.G.Z., Tan, E.L.S., Barton, P.J.R., Felkin, L.E., Lara-Pezzi, E., Angelini, G., Beltrami, C., Pravenec, M., Schafer, A., Bottolo, L., Hubner, N., Emanueli, C., Cook, S.A. and Petretto, E.
Nature Communications 10
(1): 3616.
9 August 2019
A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing.
Chen, T., Zhang, B., Ziegenhals, T., Prusty, A.B., Fröhler, S., Grimm, C., Hu, Y., Schaefke, B., Fang, L., Zhang, M., Kraemer, N., Kaindl, A.M., Fischer, U. and Chen, W.
PLoS Genetics 15
(10): e1008460.
31 October 2019
Porphyromonas gingivalis impairs oral epithelial barrier through targeting GRHL2.
Chen, W., Alshaikh, A., Kim, S., Kim, J., Chun, C., Mehrazarin, S., Lee, J., Lux, R., Kim, R.H., Shin, K.H., Park, N.H., Walentin, K., Schmidt-Ott, K.M. and Kang, M K
Journal of Dental Research 98
(10): 1150-1158.
1 September 2019
Small and large ribosomal subunit deficiencies lead to distinct gene expression signatures that reflect cellular growth rate.
Cheng, Z., Mugler, C.F., Keskin, A., Hodapp, S., Chan, L.Y.L., Weis, K., Mertins, P., Regev, A., Jovanovic, M. and Brar, G.A.
Molecular Cell 73
(1): 36-47.
3 January 2019
Blood pressure in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) controversies conference.
Cheung, A.K., Chang, T.I., Cushman, W.C., Furth, S.L., Ix, J.H., Pecoits-Filho, R., Perkovic, V., Sarnak, M.J., Tobe, S.W., Tomson, C.R.V., Cheung, M., Wheeler, D.C., Winkelmayer, W.C. and Mann, J.F.E.
Kidney International 95
(5): 1027-1036.
May 2019
Imaging markers of disability in aquaporin-4 immunoglobulin G seropositive neuromyelitis optica: a graph theory study.
Chien, C., Oertel, F.C., Siebert, N., Zimmermann, H., Asseyer, S., Kuchling, J., Scheel, M., Ruprecht, K., Bellmann-Strobl, J., Paul, F. and Brandt, A.U.
Brain Communications 1
(1): fcz026.
16 October 2019
Spinal cord lesions and atrophy in NMOSD with AQP4-IgG and MOG-IgG associated autoimmunity.
Chien, C., Scheel, M., Schmitz-Hübsch, T., Borisow, N., Ruprecht, K., Bellmann-Strobl, J., Paul, F. and Brandt, A.U.
Multiple Sclerosis Journal 25
(14): 1926-1936.
December 2019
Possible digenic disease in a caucasian family with COL4A3 and COL4A5 mutations.
Choi, M., Anistan, Y.M., Eckardt, K.U., Gollasch, M. and Nickel, P.
Nephron 141
(3): 213-218.
March 2019
Maximizing binary interactome mapping with a minimal number of assays.
Choi, S.G., Olivet, J., Cassonnet, P., Vidalain, P.O., Luck, K., Lambourne, L., Spirohn, K., Lemmens, I., Dos Santos, M., Demeret, C., Jones, L., Rangarajan, S., Bian, W., Coutant, E.P., Janin, Y.L., van der Werf, S., Trepte, P., Wanker, E.E., De Las Rivas, J., Tavernier, J., Twizere, J.C., Hao, T., Hill, D.E., Vidal, M., Calderwood, M.A. and Jacob, Y.
Nature Communications 10
(1): 3907.
29 August 2019
deltaTE: detection of translationally regulated genes by integrative analysis of Ribo-seq and RNA-seq data.
Chothani, S., Adami, E., Ouyang, J.F., Viswanathan, S., Hubner, N., Cook, S.A., Schafer, S. and Rackham, O.J.L.
Current Protocols in Molecular Biology 129
(1): e108.
December 2019
Widespread translational control of fibrosis in the human heart by RNA-binding proteins.
Chothani, S., Schäfer, S., Adami, E., Viswanathan, S., Widjaja, A.A., Langley, S.R., Tan, J., Wang, M., Quaife, N.M., Pua, C.J., D'Agostino, G., Shekeran, S.G., George, B.L., Lim, S., Cao, E.Y., van Heesch, S., Witte, F., Felkin, L.E., Christodoulou, E.G., Dong, J., Blachut, S., Patone, G., Barton, P.J.R., Hubner, N., Cook, S.A. and Rackham, O.J.L.
Circulation 140
(11): 937-951.
10 September 2019
Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.
Christen, F., Hoyer, K., Yoshida, K., Hou, H.A., Waldhueter, N., Heuser, M., Hills, R.K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W.C., Blau, I.W., Tang, J.L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Löwenberg, B., Linch, D.C., Bullinger, L., Valk, P.J.M., Tien, H.F., Gale, R.E., Ogawa, S. and Damm, F.
Blood 133
(10): 1140-1151.
7 March 2019
Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders.
Ciccarelli, O., Cohen, J.A., Reingold, S.C. and Weinshenker, B.G.
Lancet Neurology 18
(2): 185-197.
February 2019
Alternative 3' UTRs direct localization of functionally diverse protein isoforms in neuronal compartments.
Ciolli Mattioli, C., Rom, A., Franke, V., Imami, K., Arrey, G., Terne, M., Woehler, A., Akalin, A., Ulitsky, I. and Chekulaeva, M.
Nucleic Acids Research 47
(5): 2560-2573.
18 March 2019
Autophagy in the renewal, differentiation and homeostasis of immune cells.
Clarke, A.J. and Simon, A.K.
Nature Reviews Immunology 19
(3): 170-183.
March 2019
Estrus-cycle regulation of cortical inhibition.
Clemens, A.M., Lenschow, C., Beed, P., Li, L., Sammons, R., Naumann, R.K., Wang, H., Schmitz, D. and Brecht, M.
Current Biology 29
(4): 605-615.
18 February 2019
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.
Cocciardi, S., Dolnik, A., Kapp-Schwoerer, S., Rücker, F.G., Lux, S., Blätte, T.J., Skambraks, S., Krönke, J., Heidel, F.H., Schnöder, T.M., Corbacioglu, A., Gaidzik, V.I., Paschka, P., Teleanu, V., Göhring, G., Thol, F., Heuser, M., Ganser, A., Weber, D., Sträng, E., Kestler, H.A., Döhner, H., Bullinger, L. and Döhner, K.
Nature Communications 10
(1): 2031.
2 May 2019
NG-meta-profiler: fast processing of metagenomes using NGLess, a domain-specific language.
Coelho, L.P., Alves, R., Monteiro, P., Huerta-Cepas, J., Freitas, A.T. and Bork, P.
Microbiome 7
(1): 84.
3 June 2019
Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD.
Cook, L.J., Rose, J.W., Alvey, J.S., Jolley, A.M., Kuhn, R., Marron, B., Pederson, M., Enriquez, R., Yearley, J., McKechnie, S., Han, M.H., Tomczak, A.J., Levy, M., Mealy, M.A., Coleman, J., Bennett, J.L., Johnson, R., Barnes-Garcia, M., Traboulsee, A.L., Carruthers, R.L., Lee, L.E., Schubert, J.J., McMullen, K., Kister, I., Rimler, Z., Reid, A., Sicotte, N.L., Planchon, S.M., Cohen, J.A., Ivancic, D., Sedlak, J.L., Sand, I.K., Repovic, P., Amezcua, L., Pruitt, A., Amundson, E., Chitnis, T., Mullin, D.S., Klawiter, E.C., Russo, A.W., Riley, C.S., Onomichi, K.B., Levine, L., Nelson, K.E., Nealon, N.M., Engel, C., Kruse-Hoyer, M., Marcille, M., Tornes, L., Rumpf, A., Greer, A., Kenneally Behne, M., Rodriguez, R.R., Behne, D.W., Blackway, D.W., Coords, B., Blaschke, T.F., Sheard, J., Smith, T.J., Behne, J.M. and Yeaman, M.R.
Neurology Neuroimmunology & Neuroinflammation 6
(5): e583.
September 2019
Standardization of T1w/T2w ratio improves detection of tissue damage in multiple sclerosis.
Cooper, G., Finke, C., Chien, C., Brandt, A.U., Asseyer, S., Ruprecht, K., Bellmann-Strobl, J., Paul, F. and Scheel, M.
Frontiers in Neurology 10
: 334.
April 2019
Multiscale modeling of dyadic structure-function relation in ventricular cardiac myocytes.
Cosi, F.G., Giese, W., Neubert, W., Luther, S., Chamakuri, N., Parlitz, U. and Falcke, M.
Biophysical Journal 117
(12): 2409-2419.
17 December 2019
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Cossarizza, A., Chang, H.D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., Agace, W.W., Aghaeepour, N., Akdis, M., Allez, M., Almeida, L.N., Alvisi, G., Anderson, G., Andrä, I., Annunziato, F., Anselmo, A., Bacher, P., Baldari, C.T., Bari, S., Barnaba, V., Barros-Martins, J., Battistini, L., Bauer, W., Baumgart, S., Baumgarth, N., Baumjohann, D., Baying, B., Bebawy, M., Becher, B., Beisker, W., Benes, V., Beyaert, R., Blanco, A., Boardman, D.A., Bogdan, C., Borger, J.G., Borsellino, G., Boulais, P.E., Bradford, J.A., Brenner, D., Brinkman, R.R., Brooks, A.E.S., Busch, D.H., Büscher, M., Bushnell, T.P., Calzetti, F., Cameron, G., Cammarata, I., Cao, X., Cardell, S.L., Casola, S., Cassatella, M.A., Cavani, A., Celada, A., Chatenoud, L., Chattopadhyay, P.K., Chow, S., Christakou, E., Čičin-Šain, L., Clerici, M., Colombo, F.S., Cook, L., Cooke, A., Cooper, A.M., Corbett, A.J., Cosma, A., Cosmi, L., Coulie, P.G., Cumano, A., Cvetkovic, L., Dang, V.D., Dang-Heine, C., Davey, M.S., Davies, D., De Biasi, S., Del Zotto, G., Dela Cruz, G.V., Delacher, M., Della Bella, S., Dellabona, P., Deniz, G., Dessing, M., Di Santo, J.P., Diefenbach, A., Dieli, F., Dolf, A., Dörner, T., Dress, R.J., Dudziak, D., Dustin, M., Dutertre, C.A., Ebner, F., Eckle, S.B.G., Edinger, M., Eede, P., Ehrhardt, G.R.A., Eich, M., Engel, P., Engelhardt, B., Erdei, A., Esser, C., Everts, B., Evrard, M., Falk, C.S., Fehniger, T.A., Felipo-Benavent, M., Ferry, H., Feuerer, M., Filby, A., Filkor, K., Fillatreau, S., Follo, M., Förster, I., Foster, J., Foulds, G.A., Frehse, B., Frenette, P.S., Frischbutter, S., Fritzsche, W., Galbraith, D.W., Gangaev, A., Garbi, N., Gaudilliere, B., Gazzinelli, R.T., Geginat, J., Gerner, W., Gherardin, N.A., Ghoreschi, K., Gibellini, L., Ginhoux, F., Goda, K., Godfrey, D.I., Goettlinger, C., González-Navajas, J.M., Goodyear, C.S., Gori, A., Grogan, J.L., Grummitt, D., Grützkau, A., Haftmann, C., Hahn, J., Hammad, H., Hämmerling, G., Hansmann, L., Hansson, G., Harpur, C.M., Hartmann, S., Hauser, A., Hauser, A.E., Haviland, D.L., Hedley, D., Hernández, D.C., Herrera, G., Herrmann, M., Hess, C., Höfer, T., Hoffmann, P., Hogquist, K., Holland, T., Höllt, T., Holmdahl, R., Hombrink, P., Houston, J.P., Hoyer, B.F., Huang, B., Huang, F.P., Huber, J.E., Huehn, J., Hundemer, M., Hunter, C.A., Hwang, W.Y.K., Iannone, A., Ingelfinger, F., Ivison, S.M., Jäck, H.M., Jani, P.K., Jávega, B., Jonjic, S., Kaiser, T., Kalina, T., Kamradt, T., Kaufmann, S.H.E., Keller, B., Ketelaars, S.L.C., Khalilnezhad, A., Khan, S., Kisielow, J., Klenerman, P., Knopf, J., Koay, H.F., Kobow, K., Kolls, J.K., Kong, W.T., Kopf, M., Korn, T., Kriegsmann, K., Kristyanto, H., Kroneis, T., Krueger, A., Kühne, J., Kukat, C., Kunkel, D., Kunze-Schumacher, H., Kurosaki, T., Kurts, C., Kvistborg, P., Kwok, I., Landry, J., Lantz, O., Lanuti, P., LaRosa, F., Lehuen, A., LeibundGut-Landmann, S., Leipold, M.D., Leung, L.Y.T., Levings, M.K., Lino, A.C., Liotta, F., Litwin, V., Liu, Y., Ljunggren, H.G., Lohoff, M., Lombardi, G., Lopez, L., López-Botet, M., Lovett-Racke, A.E., Lubberts, E., Luche, H., Ludewig, B., Lugli, E., Lunemann, S., Maecker, H.T., Maggi, L., Maguire, O., Mair, Fl., Mair, K.H., Mantovani, A., Manz, R.A., Marshall, A.J., Martínez-Romero, A., Martrus, G., Marventano, I., Maslinski, W., Matarese, G., Mattioli, A.V., Maueröder, C., Mazzoni, A., McCluskey, J., McGrath, M., McGuire, H.M., McInnes, I.B., Mei, H.E., Melchers, F., Melzer, S., Mielenz, D., Miller, S.D., Mills, K.H.G., Minderman, H., Mjösberg, J., Moore, J., Moran, B., Moretta, L., Mosmann, T.R., Müller, S., Multhoff, G., Muñoz, L.E., Münz, C., Nakayama, T., Nasi, M., Neumann, K., Ng, L.G., Niedobitek, A., Nourshargh, S., Núñez, G., O'Connor, J.E., Ochel, A., Oja, A., Ordonez, D., Orfao, A., Orlowski-Oliver, E., Ouyang, W., Oxenius, A., Palankar, R., Panse, I., Pattanapanyasat, K., Paulsen, M., Pavlinic, D., Penter, L., Peterson, P., Peth, C., Petriz, J., Piancone, F., Pickl, W.F., Piconese, S., Pinti, M., Pockley, A.G., Podolska, M.J., Poon, Z., Pracht, K., Prinz, I., Pucillo, C.E.M., Quataert, S.A., Quatrini, L., Quinn, K.M., Radbruch, H., Radstake, T.R.D.J., Rahmig, S., Rahn, H.P., Rajwa, B., Ravichandran, G., Raz, Y., Rebhahn, J.A., Recktenwald, D., Reimer, D., Reis E Sousa, C., Remmerswaal, E.B.M., Richter, L., Rico, L.G., Riddell, A., Rieger, A.M., Robinson, J.P, Romagnani, C., Rubartelli, A., Ruland, J., Saalmüller, A., Saeys, Y., Saito, T., Sakaguchi, S., Sala-de-Oyanguren, F., Samstag, Y., Sanderson, S., Sandrock, I., Santoni, A., Sanz, R.B., Saresella, M., Sautes-Fridman, C., Sawitzki, B., Schadt, L., Scheffold, A., Scherer, H.U, Schiemann, M., Schildberg, F.A., Schimisky, E., Schlitzer, A., Schlosser, J., Schmid, S., Schmitt, S., Schober, K., Schraivogel, D., Schuh, W., Schüler, T., Schulte, R., Schulz, A.R., Schulz, S.R., Scottá, C., Scott-Algara, D., Sester, D.P., Shankey, T.V., Silva-Santos, B., Simon, A.K., Sitnik, K.M., Sozzani, S., Speiser, D.E., Spidlen, J., Stahlberg, A., Stall, A.M., Stanley, N., Stark, R., Stehle, C., Steinmetz, T., Stockinger, H., Takahama, Y., Takeda, K., Tan, L., Tárnok, A., Tiegs, G., Toldi, G., Tornack, J., Traggiai, E., Trebak, M., Tree, T.I.M., Trotter, J., Trowsdale, J., Tsoumakidou, M., Ulrich, H., Urbanczyk, S., van de Veen, W., van den Broek, M., van der Pol, E., Van Gassen, S., Van Isterdael, G., van Lier, R.A.W., Veldhoen, M., Vento-Asturias, S., Vieira, P., Voehringer, D., Volk, H.D., von Borstel, A., von Volkmann, K., Waisman, A., Walker, R.V., Wallace, P.K., Wang, S.A., Wang, X.M., Ward, M.D., Ward-Hartstonge, K.A., Warnatz, K., Warnes, G., Warth, S., Waskow, C., Watson, J.V., Watzl, C., Wegener, L., Weisenburger, T., Wiedemann, A., Wienands, J., Wilharm, A., Wilkinson, R.J., Willimsky, G., Wing, J.B., Winkelmann, R., Winkler, T.H., Wirz, O.F., Wong, A., Wurst, P., Yang, J.H.M., Yang, J., Yazdanbakhsh, M., Yu, L., Yue, A., Zhang, H., Zhao, Y., Ziegler, S.M., Zielinski, C., Zimmermann, J. and Zychlinsky, A.
European Journal of Immunology 49
(10): 1457-1973.
October 2019
Interleukin-4 supplementation improves the pathophysiology of hypertension in response to placental ischemia in RUPP rats.
Cottrell, J.N., Amaral, L.M., Harmon, A.C., Cornelius, D.C., Cunningham, M.W., Vaka, V.R., Ibrahim, T., Herse, F., Wallukat, G., Dechend, R. and LaMarca, B.D.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 316
(2): R165-R171.
February 2019
Pancreas organogenesis: the interplay between surrounding microenvironment(s) and epithelium-intrinsic factors.
Cozzitorto, C. and Spagnoli, F.M.
Current Topics in Developmental Biology 132
: 221-256.
2019
Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial.
Cree, B.A.C., Bennett, J.L., Kim, H.J., Weinshenker, B.G., Pittock, S.J., Wingerchuk, D.M., Fujihara, K., Paul, F., Cutter, G.R., Marignier, R., Green, A.J., Aktas, O., Hartung, H.P., Lublin, F.D., Drappa, J., Barron, G., Madani, S., Ratchford, J.N., She, D., Cimbora, D. and Katz, E.
Lancet 394
(10206): 1352-1363.
12 October 2019
Wnt11/Fzd7 signaling compartmentalizes AKAP2/PKA to regulate L-type Ca(2+) channel.
Csalyi, K.D., Rharass, T., Schulz, M., Phan, M.H.Q., Wakula, P., Mhatre, K.N., Plotnick, D., Werdich, A.A., Zauber, H., Sury, M.D., Selbach, M., Heinzel, F.R., Klussmann, E. and Panakova, D.
bioRxiv
: 741637.
20 August 2019
Renal natural killer cell activation and mitochondrial oxidative stress; new mechanisms in AT1-AA mediated hypertensive pregnancy.
Cunningham, M.W., Vaka, V.R., McMaster, K., Ibrahim, T., Cornelius, D.C., Amaral, L., Campbell, N., Wallukat, G., McDuffy, S., Usry, N., Dechend, R. and LaMarca, B.
Pregnancy Hypertension 15
: 72-77.
January 2019
D
Multi-sample SPIM image acquisition, processing and analysis of vascular growth in zebrafish.
Daetwyler, S., Günther, U., Modes, C.D., Harrington, K. and Huisken, J.
Development 146
(6): dev173757.
15 March 2019
Novel mutations in KMT2B offer pathophysiological insights into childhood-onset progressive dystonia.
Dafsari, H.S., Sprute, R., Wunderlich, G., Daimagüler, H.S., Karaca, E., Contreras, A., Becker, K., Schulze-Rhonhof, M., Kiening, K., Karakulak, T., Kloss, M., Horn, A., Pauls, A., Nürnberg, P., Altmüller, J., Thiele, H., Assmann, B., Koy, A. and Cirak, S.
Journal of Human Genetics 64
(8): 803-813.
August 2019
N2 year in review and message from the editor to our reviewers.
Dalmau, J., Kolson, D.L., Paul, F. and Zamvil, S.S.
Neurology Neuroimmunology & Neuroinflammation 6
(1): e525.
January 2019
The antiobese effect of AT1 receptor blockade is augmented in mice lacking Mas.
Dapper, C., Schuster, F., Stölting, I., Vogt, F., Castro e Souza, L.A., Alenina, N., Bader, M. and Raasch, W.
Naunyn-Schmiedeberg's Archives of Pharmacology 392
(7): 865-877.
July 2019
Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular K(V) currents and predisposes to ventricular arrhythmia.
David, J.P., Lisewski, U., Crump, S.M., Jepps, T.A., Bocksteins, E., Wilck, N., Lossie, J., Roepke, T.K., Schmitt, N. and Abbott, G.W.
FASEB Journal 33
(2): 2537-2552.
February 2019
Mutant FUS and ELAVL4 (HuD) aberrant crosstalk in amyotrophic lateral sclerosis.
De Santis, R., Alfano, V., de Turris, V., Colantoni, A., Santini, L., Garone, M.G., Antonacci, G., Peruzzi, G., Sudria-Lopez, E., Wyler, E., Anink, J.J., Aronica, E., Landthaler, M., Pasterkamp, R.J., Bozzoni, I. and Rosa, A.
Cell Reports 27
(13): 3818-3831.
25 June 2019
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino, G.I., Palluzzi, F., Chiariello, A.M., Piccioni, R., Bianco, S., Furia, L., De Conti, G., Bouwman, B.A.M., Melloni, G., Guido, D., Giacò, L., Luzi, L., Cittaro, D., Faretta, M., Nicodemi, M., Crosetto, N. and Pelicci, P.G.
Nature Genetics 51
(6): 1011-1023.
June 2019
Untargeted metabolomic analysis and pathway discovery in perinatal asphyxia and hypoxic-ischaemic encephalopathy.
Denihan, N.M., Kirwan, J.A., Walsh, B.H., Dunn, W.B., Broadhurst, D.I., Boylan, G.B. and Murray, D.M.
Journal of Cerebral Blood Flow and Metabolism 39
(1): 147-162.
January 2019
A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response.
Denker, S., Bittner, A., Na, I.K., Kase, J., Frick, M., Anagnostopoulos, I., Hummel, M. and Schmitt, C.A.
International Journal of Hematologic Oncology 8
(4): IJH20.
19 December 2019
Genome-wide patterns of transposon proliferation in an evolutionary young hybrid fish.
Dennenmoser, S., Sedlazeck, F.J., Schatz, M.C, Altmüller, J., Zytnicki, M. and Nolte, A.W.
Molecular Ecology 28
(6): 1491-1505.
March 2019
Organization of motor pools depends on the combined function of N-cadherin and type II cadherins.
Dewitz, C., Duan, X. and Zampieri, N.
Development 146
(13): dev180422.
10 July 2019
β-secretase BACE1 is required for normal cochlear function.
Dierich, M., Hartmann, S., Dietrich, N., Moeser, P., Brede, F., Johnson Chacko, L., Tziridis, K., Schilling, A., Krauss, P., Hessler, S., Karch, S., Schrott-Fischer, A., Blumer, M., Birchmeier, C., Oliver, D., Moser, T., Schulze, H., Alzheimer, C., Leitner, M.G. and Huth, T.
Journal of Neuroscience 39
(45): 9013-9027.
6 November 2019
PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G., Perez Hernandez, D., Kowenz-Leutz, E., Kirchner, M., Kahlert, G., Wesolowski, R., Baum, K., Knoblich, M., Hofstätter, M., Muller, A., Wolf, J., Reimer, U. and Leutz, A.
iScience 13
: 351-370.
29 March 2019
Clinical utility of a protein-based oncopanel in patients with end-stage head and neck cancer.
Doescher, J., Weissinger, S.E., Schönsteiner, S.S., Lisson, C., Bullinger, L., Barth, T.F., Leithäuser, F., Mueller-Richter, U., Laban, S., Hoffmann, T.K., Möller, P., Lennerz, J.K. and Schuler, P.J.
Immunotherapy 11
(14): 1193-1203.
October 2019
Caenorhabditis elegans and systems biology - it is 'systems' all the way down!
Dupuy, D. and Tursun, B.
Current Opinion in Systems Biology 13
: iv-vi.
February 2019
The choice of embedding media affects image quality, tissue R(2)*, and susceptibility behaviors in post‐mortem brain MR microscopy at 7.0T.
Dusek, P., Madai, V.I., Huelnhagen, T., Bahn, E., Matej, R., Sobesky, J., Niendorf, T., Acosta-Cabronero, Julio and Wuerfel, J.
Magnetic Resonance in Medicine 81
(4): 2688-2701.
April 2019
Single synapse indicators of impaired glutamate clearance derived from fast iGlu(u) imaging of cortical afferents in the striatum of normal and Huntington (Q175) mice.
Dvorzhak, A., Helassa, N., Török, K., Schmitz, D. and Grantyn, R.
Journal of Neuroscience 39
(20): 3970-3982.
15 May 2019
Sex-specific regulation of collagen I and III expression by 17β-estradiol in cardiac fibroblasts: role of estrogen receptors.
Dworatzek, E., Mahmoodzadeh, S., Schriever, C., Kusumoto, K., Kramer, L., Santos, G., Fliegner, D., Leung, Y.K., Ho, S.M., Zimmermann, W.H., Lutz, S. and Regitz-Zagrosek, V.
Cardiovascular Research 115
(2): 315-327.
1 February 2019
Oxidative stress in rheumatoid arthritis: what the future might hold regarding novel biomarkers and add-on therapies.
da Fonseca, L.J.S., Nunes-Souza, V., Goulart, M.O.F. and Rabelo, L.A.
Oxidative Medicine and Cellular Longevity 2019
(Special issue): 7536805.
16 December 2019
Physical activity during adolescence and risk of colorectal adenoma later in life: results from the Nurses' Health Study II.
de Rezende, L.F.M., Lee, D.H., Keum, N.N., Nimptsch, K., Song, M., Lee, I.M., Eluf-Neto, J., Ogino, S., Fuchs, C., Meyerhardt, J., Chan, A.T., Willett, W., Giovannucci, E. and Wu, K.
British Journal of Cancer 121
(1): 86-94.
July 2019
Diffusion-weighted renal MRI at 9.4 Tesla using RARE to improve anatomical integrity.
dos Santos Periquito, J., Paul, K., Huelnhagen, T., Ku, M.C., Ji, Y., Cantow, K., Gladytz, T., Grosenick, D., Flemming, B., Seeliger, E., Waiczies, S., Niendorf, T. and Pohlmann, A.
Scientific Reports 9
(1): 19723.
23 December 2019
E
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts.
Eckert, M.A., Coscia, F., Chryplewicz, A., Chang, J.W., Hernandez, K.M., Pan, S., Tienda, S.M., Nahotko, D.A., Li, G., Blaženović, I., Lastra, R.R., Curtis, M., Yamada, S.D., Perets, R., McGregor, S.M., Andrade, J., Fiehn, O., Moellering, R.E., Mann, M. and Lengyel, E.
Nature 569
(7758): 723-728.
30 May 2019
Aktueller Standard der Blutdruckmessung - Stellungnahme der Deutschen Hochdruckliga e. V. DHL® - Deutsche Gesellschaft für Hypertonie und Prävention [Actual standard of blood pressure measurement - statement of the German High Blood Pressure League].
Eckert, S., Ott, C., Büchner, N., Dechend, R., Lüders, S., Mengden, T. and Sanner, B.
Deutsche Medizinische Wochenschrift 144
(21): 1522-1527.
October 2019
Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma.
Edginton-White, B., Cauchy, P., Assi, S.A., Hartmann, S., Riggs, A.G., Mathas, S., Cockerill, P.N. and Bonifer, C.
Leukemia 33
(6): 1463-1474.
June 2019
Rapid molecular evolution of pain insensitivity in multiple African rodents.
Eigenbrod, O., Debus, K.Y., Reznick, J., Bennett, N.C., Sánchez-Carranza, O., Omerbašić, D., Hart, D.W., Barker, A.J., Zhong, W., Lutermann, H., Katandukila, J.V., Mgode, G., Park, T.J. and Lewin, G.R.
Science 364
(6443): 852-859.
31 May 2019
Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation.
Eitel, F., Soehler, E., Bellmann-Strobl, J., Brandt, A.U., Ruprecht, K., Giess, R.M., Kuchling, J., Asseyer, S., Weygandt, M., Haynes, J.D., Scheel, M., Paul, F. and Ritter, K.
NeuroImage: Clinical 24
: 102003.
6 September 2019
A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes.
El-Battrawy, I., Albers, S., Cyganek, L., Zhao, Z., Lan, H., Li, X., Xu, Q., Kleinsorge, M., Huang, M., Liao, Z., Zhong, R., Rudic, B., Müller, J., Dinkel, H., Lang, S., Diecke, S., Zimmermann, W.H., Utikal, J., Wieland, T., Borggrefe, M., Zhou, X. and Akin, I.
Europace 21
(9): 1410-1421.
September 2019
Studying Brugada syndrome with an SCN1B variants in human-induced pluripotent stem cell-derived cardiomyocytes.
El-Battrawy, I., Müller, J., Zhao, Z., Cyganek, L., Zhong, R., Zhang, F., Kleinsorge, M., Lan, H., Li, X., Xu, Q., Huang, M., Liao, Z., Moscu-Gregor, A., Albers, S., Dinkel, H., Lang, S., Diecke, S., Zimmermann, W.H., Utikal, J., Wieland, T., Borggrefe, M., Zhou, X. and Akin, I.
Frontiers in Cell and Developmental Biology 7
: 261.
1 November 2019
Gadolinium in human brain sections and colocalization with other elements.
El-Khatib, A.H., Radbruch, H., Trog, S., Neumann, B., Paul, F., Koch, A., Linscheid, M.W., Jakubowski, N. and Schellenberger, E.
Neurology Neuroimmunology & Neuroinflammation 6
(1): e515.
January 2019
Insight into the redox status of inflammatory skin equivalents as determined by EPR spectroscopy.
Elpelt, A., Albrecht, S., Teutloff, C., Hüging, M., Saeidpour, S., Lohan, S.B., Hedtrich, S. and Meinke, M.C.
Chemico-Biological Interactions 310
: 108752.
1 September 2019
Akutes pulmorenales Syndrom auf der Intensivstation: Rationale Diagnostik und Therapie [Acute pulmonary-renal syndrome in the intensive care unit: rational diagnostics and treatment].
Enghard, P., Erley, C. and Schreiber, A.
Nephrologe 14
: 438-445.
2 October 2019
Role of Zeb2/Sip1 in neuronal development.
Epifanova, E., Babaev, A., Newman, A.G. and Tarabykin, V.
Brain Research 1705
: 24-31.
15 February 2019
Models of polymer physics for the architecture of the cell nucleus.
Esposito, A., Annunziatella, C., Bianco, S., Chiariello, A.M., Fiorillo, L. and Nicodemi, M.
Wiley Interdisciplinary Reviews Systems Biology and Medicine 11
(4): e1444.
July 2019
Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information.
Ettrich, T.J., Schwerdel, D., Dolnik, A., Beuter, F., Blätte, T.J., Schmidt, S.A., Stanescu-Siegmund, N., Steinacker, J., Marienfeld, R., Kleger, A., Bullinger, L., Seufferlein, T. and Berger, A.W.
Scientific Reports 9
(1): 13261.
13 September 2019
F
Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Faelber, K., Dietrich, L., Noel, J.K., Wollweber, F., Pfitzner, A.K., Mühleip, A., Sánchez, R., Kudryashev, M., Chiaruttini, N., Lilie, H., Schlegel, J., Rosenbaum, E., Hessenberger, M., Matthaeus, C., Kunz, S., von der Malsburg, A., Noé, F., Roux, A., van der Laan, M., Kühlbrandt, W. and Daumke, O.
Nature 571
(7765): 429-433.
18 July 2019
Genotoxic stress-induced senescence.
Fan, D.N.Y. and Schmitt, C.A.
Methods in Molecular Biology 1896
: 93-105.
2019
Elementary calcium signaling in arterial smooth muscle.
Fan, G., Cui, Y., Gollasch, M. and Kassmann, M.
Channels 13
(1): 505-519.
4 December 2019
On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat.
Farmer, D.G.S., Pracejus, N., Dempsey, B., Turner, A., Bokiniec, P., Paton, J.F.R., Pickering, A.E., Burguet, J., Andrey, P., Goodchild, A.K., McAllen, R.M. and McMullan, S.
Journal of Physiology 597
(13): 3407-3423.
1 July 2019
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Farrelly, L.A., Thompson, R.E., Zhao, S., Lepack, A.E., Lyu, Y., Bhanu, N.V., Zhang, B., Loh, Y.H.E., Ramakrishnan, A., Vadodaria, K.C., Heard, K.J., Erikson, G., Nakadai, T., Bastle, R.M., Lukasak, B.J., Zebroski, H., Alenina, N., Bader, M., Berton, O., Roeder, R.G., Molina, H., Gage, F.H., Shen, L., Garcia, B.A., Li, H., Muir, T.W. and Maze, I.
Nature 567
(7749): 535-539.
28 March 2019
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Fecher, C., Trovò, L., Müller, S.A., Snaidero, N., Wettmarshausen, J., Heink, S., Ortiz, O., Wagner, I., Kühn, R., Hartmann, J., Karl, R.M., Konnerth, A., Korn, T., Wurst, W., Merkler, D., Lichtenthaler, S.F., Perocchi, F. and Misgeld, T.
Nature Neuroscience 22
(10): 1731-1742.
October 2019
Associations of the metabolic syndrome and its components with cognitive impairment in older adults.
Feinkohl, I., Janke, J., Hadzidiakos, D., Slooter, A., Winterer, G., Spies, C. and Pischon, T.
BMC Geriatrics 19
(1): 77.
7 March 2019
Blimp1(+) cells generate functional mouse sebaceous gland organoids in vitro.
Feldman, A., Mukha, D., Maor, I.I., Sedov, E., Koren, E., Yosefzon, Y., Shlomi, T. and Fuchs, Y.
Nature Communications 10
(1): 2348.
28 May 2019
Autocalibrated multiband CAIPIRINHA with through-time encoding: proof of principle and application to cardiac tissue phase mapping.
Ferrazzi, G., Bassenge, J.P., Wink, C., Ruh, A., Markl, M., Moeller, S., Metzger, G.J., Ittermann, B. and Schmitter, S.
Magnetic Resonance in Medicine 81
(2): 1016-1030.
February 2019
Eleven loci with new reproducible genetic associations with allergic disease risk.
Ferreira, M.A., Vonk, J.M., Baurecht, H., Marenholz, I., Tian, C., Hoffman, J.D., Helmer, Q., Tillander, A., Ullemar, V., Lu, Y., Rüschendorf, F., Hinds, D.A., Hübner, N., Weidinger, S., Magnusson, P.K., Jorgenson, E., Lee, Y.A., Boomsma, D.I., Karlsson, R., Almqvist, C., Koppelman, G.H. and Paternoster, L.
Journal of Allergy and Clinical Immunology 143
(2): 691-699.
February 2019
Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
Filippi, M., Preziosa, P., Banwell, B.L., Barkhof, F., Ciccarelli, O., De Stefano, N., Geurts, J.J.G., Paul, F., Reich, D.S., Toosy, A.T., Traboulsee, A., Wattjes, M.P., Yousry, T.A., Gass, A., Lubetzki, C., Weinshenker, B.G. and Rocca, M.A.
Brain 142
(7): 1858-1875.
July 2019
The role of Wnt and R-spondin in the stomach during health and disease.
Fischer, A.S. and Sigal, M.
Biomedicines 7
(2): 44.
19 June 2019
Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells.
Fischer, C., Metsger, M., Bauch, S., Vidal, R., Böttcher, M., Grote, P., Kliem, M. and Sauer, S.
Science Signaling 12
(581): eaao5820.
14 May 2019
Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.
Fischer, J., Walter, C., Tönges, A., Aleth, H., Costa Jordão, M.J., Leddin, M., Gröning, V., Erdmann, T., Lenz, G., Roth, J., Vogl, T., Prinz, M., Dugas, M., Jacobsen, I.D. and Rosenbauer, F.
Nature Immunology 20
(5): 546-558.
May 2019
Cluster binding studies with two anti-Thomsen-Friedenreich (anti-core-1, CD176, TF) antibodies: evidence for a multiple TF epitope.
Flechner, A., Butschak, G., Löffler, A., Rühmann, J., Nishimura, S.I., Dölling, R., Purfürst, B., Goletz, S., Danielczyk, A. and Karsten, U.
International Immunopharmacology 72
: 186-194.
July 2019
The transcription factor Hey and nuclear lamins specify and maintain cell identity.
Flint Brodsly, N., Bitman-Lotan, E., Boico, O., Shafat, A., Monastirioti, M., Gessler, M., Delidakis, C., Rincon-Arano, H. and Orian, A.
eLife 8
: e44745.
16 July 2019
Unstable TTTTA/TTTCA expansions in MARCH6 are associated with Familial Adult Myoclonic Epilepsy type 3.
Florian, R.T., Kraft, F., Leitão, E., Kaya, S., Klebe, S., Magnin, E., van Rootselaar, A.F., Buratti, J., Kühnel, T., Schröder, C., Giesselmann, S., Tschernoster, N., Altmüller, J., Lamiral, A., Keren, B., Nava, C., Bouteiller, D., Forlani, S., Jornea, L., Kubica, R., Ye, T., Plassard, D., Jost, B., Meyer, V., Deleuze, J.F., Delpu, Y., Avarello, M.D.M., Vijfhuizen, L.S., Rudolf, G., Hirsch, E., Kroes, T., Reif, P.S., Rosenow, F., Ganos, C., Vidailhet, M., Thivard, L., Mathieu, A., Bourgeron, T., Kurth, I., Rafehi, H., Steenpass, L., Horsthemke, B., LeGuern, E., Klein, K.M., Labauge, P., Bennett, M.F., Bahlo, M., Gecz, J., Corbett, M.A., Tijssen, M.A.J, van den Maagdenberg, A.M.J.M. and Depienne, C.
Nature Communications 10
(1): 4919.
29 October 2019
Evolution of protein domain architectures.
Forslund, S.K., Kaduk, M. and Sonnhammer, E.L.L.
Methods in Molecular Biology 1910
: 469-504.
2019
The role of receptor MAS in microglia-driven retinal vascular development.
Foulquier, S., Caolo, V., Swennen, G., Milanova, I., Reinhold, S., Recarti, C., Alenina, N., Bader, M., Steckelings, U M., Vanmierlo, T., Post, M.J., Jones, E.A., van Oostenbrugge, R.J. and Unger, T.
Angiogenesis 22
(4): 481-189.
November 2019
Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a clinico-genomic model to improve prognostic accuracy.
Franz, A., Ralla, B., Weickmann, S., Jung, M., Rochow, H., Stephan, C., Erbersdobler, A., Kilic, E., Fendler, A. and Jung, K.
Cancers 11
(10): 1473.
30 September 2019
Specific chromatin changes mark lateral organ founder cells in the Arabidopsis inflorescence meristem.
Frerichs, A., Engelhorn, J., Altmüller, J., Gutierrez-Marcos, J. and Werr, W.
Journal of Experimental Botany 70
(15): 3867-3879.
1 August 2019
Role of donor clonal hematopoiesis in allogeneic hematopoietic stem-cell transplantation.
Frick, M., Chan, W., Arends, C.M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida, K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhäuser, M., Blau, I.W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E.M., Spriewald, B.M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socié, G., Kroeger, N., Bullinger, L., Thiede, C. and Damm, F.
Journal of Clinical Oncology 37
(5): 375-385.
10 February 2019
Protease-activated receptor 2 deficiency mediates cardiac fibrosis and diastolic dysfunction.
Friebel, J., Weithauser, A., Witkowski, M., Rauch, B.H., Savvatis, K., Dörner, A., Tabaraie, T., Kasner, M., Moos, V., Bösel, D., Gotthardt, M., Radke, M.H., Wegner, M., Bobbert, P., Lassner, D., Tschöpe, C., Schutheiss, H.P., Felix, S.B., Landmesser, U. and Rauch, U.
European Heart Journal 40
(40): 3318-3332.
21 October 2019
Stochastic transcription in the p53-mediated response to DNA damage is modulated by burst frequency.
Friedrich, D., Friedel, L., Finzel, A., Herrmann, A., Preibisch, S. and Loewer, A.
Molecular Systems Biology 15
(12): e9068.
1 December 2019
Modified protocol of harvesting, extraction, and normalization approaches for gas chromatography mass spectrometry-based metabolomics analysis of adherent cells grown under high fetal calf serum conditions.
Fritsche-Guenther, R., Bauer, A., Gloaguen, Y., Lorenz, M. and Kirwan, J.A.
Metabolites 10
(1): 2.
18 December 2019
Editorial: critical issues in lymphoma management.
Fuchs, D. and Schmitt, C.A.
memo: Magazine of European Medical Oncology 12
(1): 1.
March 2019
Metabolic modulation regulates cardiac wall morphogenesis in zebrafish.
Fukuda, R., Aharonov, A., Ong, Y.T., Stone, O.A., El-Brolosy, M., Maischein, H.M., Potente, M., Tzahor, El. and Stainier, D.Y.R.
eLife 8
23 December 2019
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.
Funk, N., Munz, M., Ott, T., Brockmann, K., Wenninger-Weinzierl, A., Kühn, R., Vogt-Weisenhorn, D., Giesert, F., Wurst, W., Gasser, T. and Biskup, S.
Scientific Reports 9
(1): 4515.
14 March 2019
A benchmark for epithelial cell tracking.
Funke, J., Mais, L., Champion, A., Dye, N. and Kainmueller, D.
Lecture Notes in Computer Science 11134
: 437-445.
23 January 2019
G
Human stem cell models: lessons for pancreatic development and disease.
Gaertner, B., Carrano, A.C. and Sander, M.
Genes & Development 33
(21-22): 1475-1490.
1 November 2019
Supramolecular nanogels fabricated via host-guest molecular recognition as penetration enhancer for dermal drug delivery.
Gao, L., Zabihi, F., Ehrmann, S., Hedtrich, S. and Haag, R.
Journal of Controlled Release 300
: 64-72.
28 April 2019
Caloric restriction induces H(2)O(2) formation as a trigger of AMPK-eNOS-NO pathway in obese rats: role for CAMKII.
García-Prieto, C.F., Gil-Ortega, M., Plaza, A., Manzano-Lista, F.J., González-Blázquez, R., Alcalá, M., Rodríguez-Rodríguez, P., Viana, M., Aranguez, I., Gollasch, M., Somoza, B. and Fernández-Alfonso, M.S.
Free Radical Biology and Medicine 139
: 35-45.
1 August 2019
Association of intrathecal immunoglobulin G synthesis with disability worsening in multiple sclerosis.
Gasperi, C., Salmen, A., Antony, G., Bayas, A., Heesen, C., Kümpfel, T., Linker, R.A., Paul, F., Stangel, M., Tackenberg, B., Bergh, F.T., Warnke, C., Weber, F., Wiendl, H., Wildemann, B., Zettl, U.K., Ziemann, U., Zipp, F., Tumani, H., Gold, R. and Hemmer, B.
JAMA Neurology 76
(7): 841-849.
29 April 2019
Von konditionierten Ratten und gestressten Werktätigen: Rudolf Baumann und der Stress- und Umweltdiskurs in der DDR [On conditioned rats and stressed workmen: Rudolf Baumann and the discourse about stress and environment in the GDR].
Gausemeier, B.
NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin 27
(3): 311-341.
September 2019
The danger signal extracellular ATP is involved in the immunomediated damage of α-sarcoglycan-deficient muscular dystrophy.
Gazzerro, E., Baratto, S., Assereto, S., Baldassari, S., Panicucci, C., Raffaghello, L., Scudieri, P., De Battista, D., Fiorillo, C., Volpi, S., Chaabane, L., Malnati, M., Messina, G., Bruzzone, S., Traggiai, E., Grassi, F., Minetti, C. and Bruno, C.
American Journal of Pathology 189
(2): 354-369.
February 2019
Priming of LTP in amygdala and hippocampus by prior paired pulse facilitation paradigm in mice lacking brain serotonin.
Gebhardt, C., Mosienko, V., Alenina, N. and Albrecht, D.
Hippocampus 29
(7): 610-618.
July 2019
Suggestions for improving the design of clinical trials in multiple sclerosis - results of a systematic analysis of completed phase III trials.
Gehr, S., Kaiser, T., Kreutz, R., Ludwig, W.D. and Paul, F.
EPMA Journal 10
(4): 425-436.
December 2019
Were our critics right about the Stasi? AIDS disinformation and "disinformation squared" after five years.
Geissler, E. and Sprinkle, R.H.
Politics and the Life Sciences 38
(1): 32-61.
2019
ATTRACT: arterial flow as attractor for endothelial cell migration.
Georgieva, P.B., Marchuk, D.A. and Gerhardt, H.
Circulation Research 125
(3): 262-264.
July 2019
Olfactory and gustatory dysfunction in patients with autoimmune encephalitis.
Geran, R., Uecker, F.C., Prüss, H., Haeusler, K.G., Paul, F., Ruprecht, K., Harms, L. and Schmidt, F.A.
Frontiers in Neurology 10
: 480.
May 2019
The genetic landscape of cardiomyopathies.
Gerull, B., Klaassen, S. and Brodehl, A.
In:
Genetic Causes of Cardiac Disease.
Cardiac and Vascular Biology, 7
(7).
Springer, Cham, 45-91.
ISBN 978-3-030-27370-5
28 November 2019
Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning.
Geudens, I., Coxam, B., Alt, S., Gebala, V., Vion, A.C., Meier, K., Rosa, A. and Gerhardt, H.
Development 146
(16): dev.181024.
27 August 2019
Towards depth-resolved characterization of hemodynamics and oxygenation in the rat kidney.
Gladytz, T., Cantow, K., Flemming, B., Pohlmann, A., Niendorf, T., Seeliger, E. and Grosenick, D.
In: SPIE-OSA 2019, 23-25 Jun 2019, Munich, Germany.
2019
Near infrared spectroscopy system for quantitative monitoring of renal hemodynamics and oxygenation in rats.
Gladytz, T., Hoppe, A., Cantow, K., Flemming, B., Pohlmann, A., Niendorf, T., Seeliger, E. and Grosenick, D.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
1 March 2019
Advances and applications in the quest for orthologs.
Glover, N., Dessimoz, C., Ebersberger, I., Forslund, S.K., Gabaldón, T., Huerta-Cepas, J., Martin, M.J., Muffato, M., Patricio, M., Pereira, C., Sousa da Silva, A., Wang, Y., Sonnhammer, E. and Thomas, P.D.
Molecular Biology and Evolution 36
(10): 2157-2164.
October 2019
Sex differences in autoimmune disorders of the central nervous system.
Gold, S.M., Willing, A., Leypoldt, F., Paul, F. and Friese, M.A.
Seminars in Immunopathology 41
(2): 177-188.
March 2019
Maximal exercise and plasma cytochrome P450 and lipoxygenase mediators: a lipidomics study.
Gollasch, B., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 7
(13): e14165.
August 2019
Maximal exercise and erythrocyte fatty-acid status: a lipidomics study.
Gollasch, B., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 7
(8): e14040.
April 2019
Maximal exercise and erythrocyte epoxy fatty acids: a lipidomics study.
Gollasch, B., Wu, G., Dogan, I., Rothe, M., Gollasch, M. and Luft, F.C.
Physiological Reports 7
(22): e14275.
November 2019
Evaluation des Medizinischen Praktischen Jahres (PJ) an der Charité - Universitätsmedizin Berlin [Project Report: Evaluation of the Practical Year (PY) at the Charité Medical School, University Medicine Berlin].
Gollasch, M., Kube, P., Danz, B., Arens, S. and Märdian, S.
Zeitschrift fuer Evidenz, Fortbildung und Qualitaet im Gesundheitswesen 141-142
: 53-61.
May 2019
HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M., Yu, Y., Liang, L., Vuralli, D., Froehler, S., Kuehnen, P., Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J., Jia, S., Chen, W. and Raile, K.
Molecular Genetics & Genomic Medicine 7
(5): e602.
May 2019
Lung purinoceptor activation triggers ventilator-induced brain injury.
González-López, A., López-Alonso, I., Pickerodt, P.A., von Haefen, C., Amado-Rodríguez, L., Reimann, H., Niendorf, T., Kuebler, W., Albaiceta, G.M., Francis, R.C.E. and Spies, C.D.
Critical Care Medicine 47
(11): e911-e918.
November 2019
Cellular senescence: defining a path forward.
Gorgoulis, V., Adams, P.D., Alimonti, A., Bennett, D.C., Bischof, O., Bishop, C., Campisi, J., Collado, M., Evangelou, K., Ferbeyre, G., Gil, J., Hara, E., Krizhanovsky, V., Jurk, D., Maier, A.B., Narita, M., Niedernhofer, L., Passos, J.F., Robbins, P.D., Schmitt, C.A., Sedivy, J., Vougas, K., von Zglinicki, T., Zhou, D., Serrano, M. and Demaria, M.
Cell 179
(4): 813-827.
31 October 2019
An N-ethyl-N-nitrosourea (ENU)-induced Tyr265Stop mutation of the DNA polymerase accessory subunit gamma 2 (Polg2) is associated with renal calcification in mice.
Gorvin, C.M., Ahmad, B.N., Stechman, M.J., Loh, N.Y., Hough, T.A., Leo, P., Marshall, M., Sethi, S., Bentley, L., Piret, S.E., Reed, A., Jeyabalan, J., Christie, P.T., Wells, S., Simon, M.M., Mallon, A.M., Schulz, H., Huebner, N., Brown, M.A., Cox, R.D., Brown, S.D. and Thakker, R.V.
Journal of Bone and Mineral Research 34
(3): 497-507.
March 2019
Mice with a Brd4 mutation represent a new model of nephrocalcinosis.
Gorvin, C.M., Loh, N.Y., Stechman, M.J., Falcone, S., Hannan, F.M., Ahmad, B.N., Piret, S.E., Reed, A.A.C., Jeyabalan, J., Leo, P., Marshall, M., Sethi, S., Bass, P., Roberts, I., Sanderson, J., Wells, S., Hough, T.A., Bentley, L., Christie, P.T., Simon, M.M., Mallon, A.M., Schulz, H., Cox, R.D., Brown, M.A., Huebner, N., Brown, S.D. and Thakker, R.V.
Journal of Bone and Mineral Research 34
(7): 1324-1335.
July 2019
Ice-age climate adaptations trap the alpine marmot in a state of low genetic diversity.
Gossmann, T.I., Shanmugasundram, A., Börno, S., Duvaux, L., Lemaire, C., Kuhl, H., Klages, S., Roberts, L.D., Schade, S., Gostner, J.M., Hildebrand, F., Vowinckel, J., Bichet, C., Mülleder, M., Calvani, E., Zelezniak, A., Griffin, J.L., Bork, P., Allaine, D., Cohas, A., Welch, J.J., Timmermann, B. and Ralser, M.
Current Biology 29
(10): 1712-1720.
20 May 2019
Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.
Graetz, C., Gröger, A., Luessi, F., Salmen, A., Zöller, D., Schultz, J., Siller, N., Fleischer, V., Bellenberg, B., Berthele, A., Biberacher, V., Havla, J., Hecker, M., Hohlfeld, R., Infante-Duarte, C., Kirschke, J.S., Kümpfel, T., Linker, R., Paul, F., Pfeuffer, S., Sämann, P., Toenges, G., Weber, F., Zettl, U.K., Jahn-Eimermacher, A., Antony, G., Groppa, S., Wiendl, H., Hemmer, B., Mühlau, M., Lukas, C., Gold, R., Lill, C.M. and Zipp, F.
Multiple Sclerosis Journal 25
(5): 661-668.
1 April 2019
sgRNA sequence motifs blocking efficient CRISPR/Cas9-mediated gene editing.
Graf, R., Li, X., Chu, V.T. and Rajewsky, K.
Cell Reports 26
(5): 1098-1103.
29 January 2019
BCR-dependent lineage plasticity in mature B cells.
Graf, R., Seagal, J., Otipoby, K.L., Lam, K.P., Ayoub, S., Zhang, B., Sander, S., Chu, V.T. and Rajewsky, K.
Science 363
(6428): 748-753.
15 February 2019
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.
Greenwald, W.W., Chiou, J., Yan, J., Qiu, Y., Dai, N., Wang, A., Nariai, N., Aylward, A., Han, J.Y., Kadakia, N., Regue, L., Okino, M.L., Drees, F., Kramer, D., Vinckier, N., Minichiello, L., Gorkin, D., Avruch, J., Frazer, K.A., Sander, M., Ren, B. and Gaulton, K.J.
Nature Communications 10
(1): 2078.
7 May 2019
Combined targeted resequencing of cytosine DNA methylation and mutations of DNA repair genes with potential use for poly(ADP-ribose) polymerase 1 inhibitor sensitivity testing.
Grimm, C., Fischer, A., Farrelly, A.M., Kalachand, R., Castiglione, R., Wasserburger, E., Hussong, M., Schultheis, Anne M, Altmüller, J., Thiele, H., Reinhardt, H.C., Hauschulz, K., Hennessy, B.T., Herwig, R., Lienhard, M., Buettner, R. and Schweiger, M.R.
Journal of Molecular Diagnostics 21
(2): 198-213.
March 2019
CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
Gross, C.C., Meyer, C., Bhatia, U., Yshii, L., Kleffner, I., Bauer, J., Tröscher, A.R., Schulte-Mecklenbeck, A., Herich, S., Schneider-Hohendorf, T., Plate, H., Kuhlmann, T., Schwaninger, M., Brück, W., Pawlitzki, M., Laplaud, D.A., Loussouarn, D., Parratt, J., Barnett, M., Buckland, M.E., Hardy, T.A., Reddel, S.W., Ringelstein, M., Dörr, J., Wildemann, B., Kraemer, M., Lassmann, H., Höftberger, R., Beltrán, E., Dornmair, K., Schwab, N., Klotz, L., Meuth, S.G., Martin-Blondel, G., Wiendl, H. and Liblau, R.
Nature Communications 10
(1): 5779.
18 December 2019
TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Grund, A., Szaroszyk, M., Korf-Klingebiel, M., Malek Mohammadi, M., Trogisch, F.A., Schrameck, U., Gigina, A., Tiedje, C., Gaestel, M., Kraft, T., Hegermann, J., Batkai, S., Thum, T., Perrot, A., Remedios, C.D., Riechert, E., Völkers, M., Doroudgar, S., Jungmann, A., Bauer, R., Yin, X., Mayr, M., Wollert, K.C., Pich, A., Xiao, H., Katus, H.A., Bauersachs, J., Müller, O.J. and Heineke, J.
EMBO Molecular Medicine 11
(10): e10018.
1 October 2019
Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction.
Grune, J., Ritter, D., Kräker, K., Pappritz, K., Beyhoff, N., Schütte, T., Ott, C., John, C., van Linthout, S., Tschöpe, C., Dechend, R., Muller, D.N., Haase, N., Grune, T., Kintscher, U. and Kuebler, W.M.
Cardiovascular Ultrasound 17
(1): 7.
22 April 2019
Altered microRNA and target gene expression related to tetralogy of fallot.
Grunert, M., Appelt, S., Dunkel, I., Berger, F. and Sperling, S.R.
Scientific Reports 9
(1): 19063.
13 December 2019
Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement.
Grushevskyi, E.O., Kukaj, T., Schmauder, R., Bock, A., Zabel, U., Schwabe, T., Benndorf, K. and Lohse, M.J.
Proceedings of the National Academy of Sciences of the United States of America 116
(20): 10150-10155.
14 May 2019
Serine protease mauritanicain from euphorbia mauritanica and phorbol-12-myristate-13-acetate modulate the IL-8 release in fibroblasts and HaCaT keratinocytes.
Guenther, F., Maus, D., Hedtrich, S. and Melzig, M.F.
Planta Medica 85
(7): 578-582.
May 2019
Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells.
Guimarães, P.B., da Silva, R.F., Hoff, C.C., Fernandes, L., Nakaie, C.R., Chagas, J.R., Karaoglanovic Carmona, A., Bader, M. and Pesquero, J.B.
Inflammation Research 68
(10): 845-855.
October 2019
Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity.
Guo, J., Bertalan, G., Meierhofer, D., Klein, C., Schreyer, S., Steiner, B., Wang, S., Vieira da Silva, R., Infante-Duarte, C., Koch, S., Boehm-Sturm, P., Braun, J. and Sack, I.
Acta Biomaterialia 99
: 433-442.
November 2019
Quantitative proteome landscape of the NCI-60 cancer cell lines.
Guo, T., Luna, A., Rajapakse, V.N., Koh, C.C., Wu, Z., Liu, W., Sun, Y., Gao, H., Menden, M.P., Xu, C., Calzone, L., Martignetti, L., Auwerx, C., Buljan, M., Banaei-Esfahani, A., Ori, A., Iskar, M., Gillet, L., Bi, R., Zhang, J., Zhang, H., Yu, C., Zhong, Q., Varma, S., Schmitt, U., Qiu, P., Zhang, Q., Zhu, Y., Wild, P.J., Garnett, M.J., Bork, P., Beck, M., Liu, K., Saez-Rodriguez, J., Elloumi, F., Reinhold, W.C., Sander, C., Pommier, Y. and Aebersold, R.
iScience 21
: 664-680.
31 October 2019
Microglia/brain macrophages as central drivers of brain tumor pathobiology.
Gutmann, D.H. and Kettenmann, H.
Neuron 104
(3): 442-449.
6 November 2019
Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism.
Göppner, C., Orozco, I.J., Hoegg-Beiler, M.B., Soria, A.H., Hübner, C.A., Fernandes-Rosa, F.L., Boulkroun, S., Zennaro, M.C. and Jentsch, T.J.
Nature Communications 10
(1): 4678.
15 October 2019
H
Tenascin C regulates multiple microglial functions involving TLR4 signaling and HDAC1.
Haage, V., Elmadany, N., Roll, L., Faissner, A., Gutmann, D.H., Semtner, M. and Kettenmann, H.
Brain Behavior and Immunity 81
: 470-483.
October 2019
Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.
Haage, V., Semtner, M., Oliveira Vidal, R., Perez Hernandez, D., Pong, W.W., Chen, Z., Hambardzumyan, D., Magrini, V., Ly, A., Walker, J., Mardis, E., Mertins, P., Sauer, S., Kettenmann, H. and Gutmann, D.H.
Acta Neuropathologica Communications 7
(1): 20.
14 February 2019
Sodium chloride triggers Th17 mediated autoimmunity.
Haase, S., Wilck, N., Kleinewietfeld, M., Müller, D.N. and Linker, R.A.
Journal of Neuroimmunology 329
: 9-13.
15 April 2019
Circulating MACC1 transcripts in glioblastoma patients predict prognosis and treatment response.
Hagemann, C., Neuhaus, N., Dahlmann, M., Kessler, A.F., Kobelt, D., Herrmann, P., Eyrich, M., Freitag, B., Linsenmann, T., Monoranu, C.M., Ernestus, R.I., Löhr, M. and Stein, U.
Cancers 11
(6): 825.
13 June 2019
MRG-1/MRG15 is a barrier for germ cell to neuron reprogramming in Caenorhabditis elegans.
Hajduskova, M., Baytek, G., Kolundzic, E., Gosdschan, A., Kazmierczak, M., Ofenbauer, A., Beato del Rosal, M.L., Herzog, S., ul Fatima, N., Mertins, P., Seelk-Müthel, S. and Tursun, B.
Genetics 211
(1): 121-139.
1 January 2019
3D high resolution imaging of human heart for visualization of the cardiac structure.
Haliot, K., Magat, J., Ozenne, V., Abell, E., Dubes, V., Bear, L., Gilbert, S.H., Trew, M.L., Haissaguerre, M., Quesson, B. and Bernus, O.
Lecture Notes in Computer Science 11504
: 196-207.
30 May 2019
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
Han, Y., Lindner, S., Bei, Y., Garcia, H.D., Timme, N., Althoff, K., Odersky, A., Schramm, A., Lissat, A., Künkele, A., Deubzer, H.E., Eggert, A., Schulte, J.H. and Henssen, A.G.
Cancer Letters 445
: 24-33.
31 March 2019
The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons.
Handara, G., Hetsch, F.J.A., Jüttner, R., Schick, A., Haupt, C., Rathjen, F.G. and Kröger, S.
Developmental Biology 445
(1): 54-67.
1 January 2019
GOPHER: Generator Of Probes for capture Hi-C Experiments at high Resolution.
Hansen, P., Ali, S., Blau, H., Danis, D., Hecht, J., Kornak, U., Lupiáñez, D.G., Mundlos, S., Steinhaus, R. and Robinson, P.N.
BMC Genomics 20
(1): 40.
14 January 2019
Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment.
Haremaki, T., Metzger, J.J., Rito, T., Ozair, M.Z., Etoc, F. and Brivanlou, A.H.
Nature Biotechnology 37
(10): 1198-1208.
October 2019
Parallel generation of easily selectable multiple nephronal cell types from human pluripotent stem cells.
Hariharan, K., Stachelscheid, H., Rossbach, B., Oh, S.J., Mah, N., Schmidt-Ott, K., Kurtz, A. and Reinke, P.
Cellular and Molecular Life Sciences 76
(1): 179-192.
January 2019
R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.
Harnack, C., Berger, H., Antanaviciute, A., Vidal, R., Sauer, S., Simmons, A., Meyer, T.F. and Sigal, M.
Nature Communications 10
(1): 4368.
25 September 2019
Escalation of memory length in finite populations.
Harrington, K. and Pollack, J.
Artificial Life 25
(1): 22-32.
2 April 2019
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk.
Hart, P.C., Kenny, H.A., Grassl, N., Watters, K.M., Litchfield, L.M., Coscia, F., Blaženović, I., Ploetzky, L., Fiehn, O., Mann, M., Lengyel, E. and Romero, I.L.
Cell Reports 29
(12): 4086-4098.
17 December 2019
Criteria for surveys: from the European Association of Cardiovascular Imaging Scientific Initiatives Committee.
Haugaa, K.H., Marsan, N.A., Cameli, M., D'Andrea, A., Dweck, M.R., Carvalho, R.F., Holte, E., Manka, R., Michalski, B., Podlesnikar, T., Popescu, B.A., Schulz-Menger, J., Sitges, M., Stankovic, I., Maurer, G. and Edvardsen, T.
European Heart Journal - Cardiovascular Imaging 20
(9): 963-966.
September 2019
Deleterious somatic variants in 473 consecutive individuals with ovarian cancer: results of the observational AGO-TR1 study (NCT02222883).
Hauke, J., Hahnen, E., Schneider, S., Reuss, A., Richters, L., Kommoss, S., Heimbach, A., Marmé, F., Schmidt, S., Prieske, K., Gevensleben, H., Burges, A., Borde, J., De Gregorio, N., Nürnberg, P., El-Balat, A., Thiele, H., Hilpert, F., Altmüller, J., Meier, W., Dietrich, D., Kimmig, R., Schoemig-Markiefka, B., Kast, K., Braicu, E., Baumann, K., Jackisch, C., Park-Simon, T.W., Ernst, C., Hanker, L., Pfisterer, J., Schnelzer, A., du Bois, A., Schmutzler, R.K. and Harter, P.
Journal of Medical Genetics 56
(9): 574-580.
September 2019
Multiregion human bladder cancer sequencing reveals tumour evolution, bladder cancer phenotypes and implications for targeted therapy.
Heide, T., Maurer, A., Eipel, M., Knoll, K., Geelvink, M., Veeck, J., Knuechel, R., van Essen, J., Stoehr, R., Hartmann, A., Altmueller, J., Graham, T.A. and Gaisa, N.T.
Journal of Pathology 248
(2): 230-242.
June 2019
Structural features of tight-junction proteins.
Heinemann, U. and Schuetz, A.
International Journal of Molecular Sciences 20
(23): 6020.
29 November 2019
E47 modulates hepatic glucocorticoid action.
Hemmer, M.C., Wierer, M., Schachtrup, K., Downes, M., Hübner, N., Evans, R.M. and Uhlenhaut, N.H.
Nature Communications 10
(1): 306.
18 January 2019
Endothelial calcineurin signaling restrains metastatic outgrowth by regulating Bmp2.
Hendrikx, S., Coso, S., Prat-Luri, B., Wetterwald, L., Sabine, A., Franco, C.A., Nassiri, S., Zangger, N., Gerhardt, H., Delorenzi, M. and Petrova, T.V.
Cell Reports 26
(5): 1227-1241.
29 January 2019
Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart.
Hennig, M., Ewering, L., Pyschny, S., Shimoyama, S., Olecka, M., Ewald, D., Magarin, M., Uebing, A., Thierfelder, L., Jux, C. and Drenckhahn, J.D.
Scientific Reports 9
(1): 15126.
22 October 2019
Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine.
Herberg, M., Siebert, S., Quaas, M., Thalheim, T., Rother, K., Hussong, M., Altmüller, J., Kerner, C., Galle, J., Schweiger, M.R. and Aust, G.
Clinical Epigenetics 11
(1): 65.
27 April 2019
Preclinical evaluation of a cell-based gene therapy using the Sleeping Beauty transposon system in choroidal neovascularization.
Hernandez, M., Recalde, S., Garcia-Garcia, L., Bezunartea, J., Miskey, C., Johnen, S., Diarra, S., Sebe, A., Rodriguez-Madoz, J.R., Pouillot, S., Marie, C., Izsvák, Z., Scherman, D., Kropp, M., Prosper, F., Thumann, G., Ivics, Z., Garcia-Layana, A. and Fernandez-Robredo, P.
Molecular Therapy - Methods and Clinical Development 15
: 403-417.
13 December 2019
Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
Herrlinger, U., Tzaridis, T., Mack, F., Steinbach, J.P., Schlegel, U., Sabel, M., Hau, P., Kortmann, R.D., Krex, D., Grauer, O., Goldbrunner, R., Schnell, O., Bähr, O., Uhl, M., Seidel, C., Tabatabai, G., Kowalski, T., Ringel, F., Schmidt-Graf, F., Suchorska, B., Brehmer, S., Weyerbrock, A., Renovanz, M., Bullinger, L., Galldiks, N., Vajkoczy, P., Misch, M., Vatter, H., Stuplich, M., Schäfer, N., Kebir, S., Weller, J., Schaub, C., Stummer, W., Tonn, J.C., Simon, M., Keil, V.C., Nelles, M., Urbach, H., Coenen, M., Wick, W., Weller, M., Fimmers, R., Schmid, M., Hattingen, E., Pietsch, T., Coch, C. and Glas, M.
Lancet 393
(10172): 678-688.
16 February 2019
A C/EBPα-Wnt connection in gut homeostasis and carcinogenesis.
Heuberger, J., Hill, U., Förster, S., Zimmermann, K., Malchin, V., Kühl, A.A., Stein, U., Vieth, M., Birchmeier, W. and Leutz, A.
Life Science Alliance 2
(1): e201800173.
February 2019
Context-dependent signaling of CXC chemokine receptor 4
and atypical chemokine receptor 3.
Heuninck, J., Perpina Viciano, C., Işbilir, A., Caspar, B., Capoferri, D., Briddon, S.J., Durroux, T., Hill, S.J., Lohse, M.J., Milligan, G., Pin, J.P. and Hoffmann, C.
Molecular Pharmacology 96
(6): 778-793.
December 2019
Codon bias confers stability to human mRNAs.
Hia, F., Yang, S.F., Shichino, Y., Yoshinaga, M., Murakawa, Y., Vandenbon, A., Fukao, A., Fujiwara, T., Landthaler, M., Natsume, T., Adachi, S., Iwasaki, S. and Takeuchi, O.
EMBO Reports 20
(11): e48220.
5 November 2019
Sample preservation and storage significantly impact taxonomic and functional profiles in metaproteomics studies of the human gut microbiome.
Hickl, O., Heintz-Buschart, A., Trautwein-Schult, A., Hercog, R., Bork, P., Wilmes, P. and Becher, D.
Microorganisms 7
(9): 367.
19 September 2019
Antibiotics-induced monodominance of a novel gut bacterial order.
Hildebrand, F., Moitinho-Silva, L., Blasche, S., Jahn, M.T.T., Gossmann, T.I., Heuerta Cepas, J., Hercog, R., Luetge, M., Bahram, M., Pryszlak, A., Alves, R.J., Waszak, S.M., Zhu, A., Ye, L., Costea, P.I., Aalvink, S., Belzer, C., Forslund, S.K., Sunagawa, S., Hentschel, U., Merten, C., Patil, K.R., Benes, V. and Bork, P.
Gut 68
(10): 1781-1790.
9 September 2019
Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming.
Hoerst, K., van den Broek, L., Sachse, C., Klein, O., von Fritschen, U., Gibbs, S. and Hedtrich, S.
Journal of Molecular Medicine 97
(6): 761-775.
1 June 2019
A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury.
Hoff, U., Bubalo, G., Fechner, M., Blum, M., Zhu, Y., Pohlmann, A., Hentschel, J., Arakelyan, K., Seeliger, E., Flemming, B., Gürgen, D., Rothe, M., Niendorf, T., Manthati, V.L., Falck, J.R., Haase, M., Schunck, W.H. and Dragun, D.
Acta Physiologica 227
(2): e13297.
October 2019
Autoantibodies activating the β2-adrenergic receptor characterize patients with primary and secondary glaucoma.
Hohberger, B., Kunze, R., Wallukat, G., Kara, K., Mardin, C.Y., Lämmer, R., Schlötzer-Schrehardt, U., Hosari, S., Horn, F., Munoz, L. and Herrmann, M.
Frontiers in Immunology 10
: 2112.
October 2019
RNA tomography for spatially resolved transcriptomics (Tomo-seq).
Holler, K. and Junker, J.P.
Methods in Molecular Biology 1920
: 129-141.
2019
Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial.
Horwitz, S., O'Connor, O.A., Pro, B., Illidge, T., Fanale, M., Advani, R., Bartlett, N.L., Christensen, J.H., Morschhauser, F., Domingo-Domenech, E., Rossi, G., Kim, W.S., Feldman, T., Lennard, A., Belada, D., Illés, A., Tobinai, K., Tsukasaki, K., Yeh, S.P., Shustov, A., Hüttmann, A., Savage, K.J., Yuen, S., Iyer, S., Zinzani, P.L., Hua, Z., Little, M., Rao, S., Woolery, J., Manley, T. and Trümper, L.
Lancet 393
(10168): 229-240.
19 January 2019
Genetics of intellectual disability in consanguineous families.
Hu, H., Kahrizi, K., Musante, L., Fattahi, Z., Herwig, R., Hosseini, M., Oppitz, C., Abedini, S.S., Suckow, V., Larti, F., Beheshtian, M., Lipkowitz, B., Akhtarkhavari, T., Mehvari, S., Otto, S., Mohseni, M., Arzhangi, S., Jamali, P., Mojahedi, F., Taghdiri, M., Papari, E., Soltani Banavandi, M.J., Akbari, S., Tonekaboni, S.H., Dehghani, H., Ebrahimpour, M.R., Bader, I., Davarnia, B., Cohen, M., Khodaei, H., Albrecht, B., Azimi, S., Zirn, B., Bastami, M., Wieczorek, D., Bahrami, G., Keleman, K., Vahid, L.N., Tzschach, A., Gärtner, J., Gillessen-Kaesbach, G., Varaghchi, J.R., Timmermann, B., Pourfatemi, F., Jankhah, A., Chen, W., Nikuei, P., Kalscheuer, V.M., Oladnabi, M., Wienker, T.F., Ropers, H.H. and Najmabadi, H.
Molecular Psychiatry 24
(7): 1027-1039.
July 2019
GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Hu, X., Matsumoto, K., Jung, R.S., Weston, T.A., Heizer, P.J., He, C., Sandoval, N.P., Allan, C.M., Tu, Y., Vinters, H.V., Liau, L.M., Ellison, R.M., Morales, J.E., Baufeld, L.J., Bayley, N.A., He, L., Betsholtz, C., Beigneux, A.P., Nathanson, D.A., Gerhardt, H., Young, S.G., Fong, L.G. and Jiang, H.
eLife 8
: e47178.
6 June 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Huang, A., Shinde, P.V., Huang, J., Senff, T., Xu, H.C., Margotta, C., Häussinger, D., Willnow, T.E., Zhang, J., Pandyra, A.A., Timm, J., Weggen, S., Lang, K.S. and Lang, P.A.
JCI Insight 4
(17): e129856.
5 September 2019
Vibrational spectroscopy as a powerful tool for follow-up immunoadsorption therapy treatment of dilated cardiomyopathy - a case report.
Huang, J., Ramoji, A., Guo, S., Bocklitz, T., Boivin-Jahns, V., Möller, J., Kiehntopf, M., Noutsias, M., Popp, J. and Neugebauer, U.
Analyst 145
(2): 486-496.
15 November 2019
Early hearing loss upon disruption of Slc4a10 in C57BL/6 mice.
Huebner, A.K., Maier, H., Maul, A., Nietzsche, S., Herrmann, T., Praetorius, J. and Hübner, C.A.
Journal of the Association for Research in Otolaryngology 20
(3): 233-245.
June 2019
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses.
Huerta-Cepas, J., Szklarczyk, D., Heller, D., Hernández-Plaza, A., Forslund, S.K., Cook, H., Mende, D.R., Letunic, I., Rattei, T., Jensen, L.J., von Mering, C. and Bork, P.
Nucleic Acids Research 47
(D1): D309-D314.
8 January 2019
Targeting the tumor microenvironment of leukemia and lymphoma.
Höpken, U.E. and Rehm, A.
Trends in Cancer 5
(6): 351-364.
June 2019
BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples.
Hörl, D., Rojas Rusak, F., Preusser, F., Tillberg, P., Randel, N., Chhetri, R.K., Cardona, A., Keller, P.J., Harz, H., Leonhardt, H., Treier, M. and Preibisch, S.
Nature Methods 16
(9): 870-874.
September 2019
I
Live-imaging readouts and cell models for phenotypic profiling of mitochondrial function.
Iannetti, E.F., Prigione, A., Smeitink, J.A.M., Koopman, W.J.H., Beyrath, J. and Renkema, H.
Frontiers in Genetics 10
: 131.
March 2019
Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.
Ibarra Urizar, A., Prause, M., Wortham, M., Sui, Y., Thams, P., Sander, M., Christensen, G.L. and Billestrup, N.
Molecular and Cellular Endocrinology 496
: 110524.
1 October 2019
Discontinuous shear-thinning in adhesive dispersions.
Irani, E., Chaudhuri, P. and Heussinger, C.
Physical Review Fluids 4
(7): 074307.
18 July 2019
J
Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes.
Jacobi, S.F., Khajavi, N., Kleinau, G., Teumer, A., Scheerer, P., Homuth, G., Völzke, H., Wiegand, S., Kühnen, P., Krude, H., Gong, M., Raile, K. and Biebermann, H.
Diabetes Obesity and Metabolism 21
(5): 1168-1176.
May 2019
Multiple sclerosis-related fatigue: altered resting-state functional connectivity of the ventral striatum and dorsolateral prefrontal cortex.
Jaeger, S., Paul, F., Scheel, M., Brandt, A., Heine, J., Pach, D., Witt, C.M., Bellmann-Strobl, J. and Finke, C.
Multiple Sclerosis Journal 25
(4): 554-564.
April 2019
A combined miRNA-piRNA signature to detect Alzheimer's disease.
Jain, G., Stuendl, A., Rao, P., Berulava, T., Pena Centeno, T., Kaurani, L., Burkhardt, S., Delalle, I., Kornhuber, J., Hüll, M., Maier, W., Peters, O., Esselmann, H., Schulte, C., Deuschle, C., Synofzik, M., Wiltfang, J., Mollenhauer, B., Maetzler, W., Schneider, A. and Fischer, A.
Translational Psychiatry 9
(1): 250.
7 October 2019
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
Jakobsen, J.S., Laursen, L.G., Schuster, M.B., Pundhir, S., Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mönch, K., Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. and Porse, B.T.
Science Advances 5
(7): eaaw4304.
July 2019
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia.
James, A.R., Schroeder, M.P., Neumann, M., Bastian, L., Eckert, C., Gökbuget, N., Tanchez, J.O., Schlee, C., Isaakidis, K., Schwartz, S., Burmeister, T., von Stackelberg, A., Rieger, M.A., Göllner, S., Horstman, M., Schrappe, M., Kirschner-Schwabe, R., Brüggemann, M., Müller-Tidow, C., Serve, H., Akalin, A. and Baldus, C.D.
Journal of Hematology & Oncology 12
(1): 8.
14 January 2019
Fabrication of kidney proximal tubule grafts using biofunctionalized electrospun polymer scaffolds.
Jansen, K., Castilho, M., Aarts, S., Kaminski, M.M., Lienkamp, S.S., Pichler, R., Malda, J., Vermonden, T., Jansen, J. and Masereeuw, R.
Macromolecular Bioscience 19
(2): e1800412.
February 2019
Myelinoclastic diffuse sclerosis (Schilder's disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures.
Jarius, S., Haas, J., Paul, F. and Wildemann, B.
Journal of Neuroinflammation 16
(1): 51.
28 February 2019
A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells.
Jin, W., Mulas, F., Gaertner, B., Sui, Y., Wang, J., Matta, I., Zeng, C., Vinckier, N., Wang, A., Nguyen-Ngoc, K.V., Chiou, J., Kaestner, K.H., Frazer, K.A., Carrano, A.C., Shih, H.P. and Sander, M.
iScience 21
: 681-694.
22 November 2019
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
Jochner, M.C.E., An, J., Lättig-Tünnemann, G., Kirchner, M., Dagane, A., Dittmar, G., Dirnagl, U., Eickholt, B.J. and Harms, C.
Scientific Reports 9
(1): 3183.
28 February 2019
Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).
Johnen, A., Bürkner, P.C., Landmeyer, N.C., Ambrosius, B., Calabrese, P., Motte, J., Hessler, N., Antony, G., König, I.R., Klotz, L., Hoshi, M.M., Aly, L., Groppa, S., Luessi, F., Paul, F., Tackenberg, B., Bergh, F.T., Kümpfel, T., Tumani, H., Stangel, M., Weber, F., Bayas, A., Wildemann, B., Heesen, C., Zettl, U.K., Zipp, F., Hemmer, B., Meuth, S.G., Gold, R., Wiendl, H. and Salmen, A.
Journal of Neurology 266
(2): 386-397.
February 2019
Lymphocyte characterization of decidua basalis spiral arteries with acute atherosis in preeclamptic and normotensive pregnancies.
Johnsen, G.M., Størvold, G.L., Alnaes-Katjavivi, P.H., Roald, B., Golic, M., Dechend, R., Redman, C.W.G. and Staff, A.C.
Journal of Reproductive Immunology 132
: 42-48.
April 2019
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi, K., de Massy, M.R., Ismail, M., Reading, J.L., Uddin, I., Woolston, A., Hatipoglu, E., Oakes, T., Rosenthal, R., Peacock, T., Ronel, T., Noursadeghi, M., Turati, V., Furness, A.J.S., Georgiou, A., Wong, Y.N.S., Ben Aissa, A., Sunderland, M.W., Jamal-Hanjani, M., Veeriah, S., Birkbak, N.J., Wilson, G.A., Hiley, C.T., Ghorani, E., Guerra-Assunção, J.A., Herrero, J., Enver, T., Hadrup, S.R., Hackshaw, A., Peggs, K.S., McGranahan, N., Swanton, C., Quezada, S.A. and Chain, B.
Nature Medicine 25
(10): 1549-1559.
October 2019
Multiple two-photon targeted whole-cell patch-clamp recordings from monosynaptically connected neurons in vivo.
Jouhanneau, J.S. and Poulet, J.F.A.
Frontiers in Synaptic Neuroscience 11
: 15.
May 2019
In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids.
Jun, Y., Lee, J.S., Choi, S., Yang, J.H., Sander, M., Chung, S. and Lee, S.H.
Science Advances 5
(11): eaax4520.
1 November 2019
Detouring the roadblocks in gene expression.
Junker, J.P.
Nature Reviews Molecular Cell Biology 20
(4): 197.
April 2019
Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function.
Jurek, B., Chayka, M., Kreye, J., Lang, K., Kraus, L., Fidzinski, P., Kornau, H.C., Dao, L.M., Wenke, N.K., Long, M., Rivalan, M., Winter, Y., Leubner, J., Herken, J., Mayer, S., Mueller, S., Boehm-Sturm, P., Dirnagl, U., Schmitz, D., Kölch, M. and Prüss, H.
Annals of Neurology 86
(5): 656-670.
November 2019
SSBP1 mutations in dominant optic atrophy with variable retinal degeneration.
Jurkute, N., Leu, C., Pogoda, H.M., Arno, G., Robson, A.G., Nürnberg, G., Altmüller, J., Thiele, H., Motameny, S., Toliat, M.R., Powell, K., Höhne, W., Michaelides, M., Webster, A.R., Moore, A.T., Hammerschmidt, M., Nürnberg, P., Yu-Wai-Man, P. and Votruba, M.
Annals of Neurology 86
(3): 368-383.
September 2019
Immunhistochemische Analyse von Bcl-2, nukleärem S100A4, MITF und Ki67 zur Risikostratifizierung von Melanomen im Frühstadium - ein kombinierter immunhistochemischer Score.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
(8): 800-809.
August 2019
Immunohistochemical analysis of Bcl-2, nuclear S100A4, MITF and Ki67 for risk stratification of early-stage melanoma - a combined IHC score for melanoma risk stratification.
Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. and von Laffert, M.
Journal der Deutschen Dermatologischen Gesellschaft 17
(8): 800-808.
August 2019
Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi, J.S., Basu, T., Pellmann, M., Kaiser, S., Steinemann, D., Sanders, M.A., Hinai, A.S.A., Zeilemaker, A., Bojtine Kovacs, S., Koellerer, C., Ostendorp, J., Aumann, K., Wang, W., Raffoux, E., Cassinat, B., Bullinger, L., Schlegelberger, B., Valk, P.J.M. and Pahl, H.L.
Blood 133
(16): 1766-1777.
18 April 2019
Angiotensin-(1-7) receptor Mas in hemodynamic and thermoregulatory dysfunction after high-level spinal cord injury in mice: a pilot study.
Järve, A., Todiras, M., Kny, M., Fischer, F.I., Kraemer, J.F., Wessel, N., Plehm, R., Fielitz, J., Alenina, N. and Bader, M.
Frontiers in Physiology 9
: 1930.
January 2019
Distinct roles of angiotensin receptors in autonomic dysreflexia following high-level spinal cord injury in mice.
Järve, A., Todiras, M., Lian, X, Filippelli-Silva, R., Qadri, F., Martin, R.P., Gollasch, M. and Bader, M.
Experimental Neurology 311
: 173-181.
January 2019
K
Cytotoxic effects of rabbit anti-thymocyte globulin preparations on primary human thymic epithelial cells.
Kaebisch, E.M., Cho, M.Y., Oh, Y.S., Olfe, L.I., Szyska, M., Becker, S.C., Reinke, P., Volk, H.D., Gillissen, B., Bullinger, L., Thiel, A. and Na, I.K.
Transplantation 103
(11): 2234-2244.
November 2019
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes, I., Szulzewsky, F., Chen, Z., Herting, C.J., Gabanic, B., Velázquez Vega, J.E., Shelton, J., Switchenko, J.M., Ross, J.L., McSwain, L.F., Huse, J.T., Westermark, B., Nelander, S., Forsberg-Nilsson, K., Uhrbom, L., Maturi, N.P., Cimino, P.J., Holland, E.C., Kettenmann, H., Brennan, C.W., Brat, D.J. and Hambardzumyan, D.
OncoImmunology 8
(11): e1655360.
22 August 2019
Nanocapsule induced morphology and migration changes in single cell layers quantified with digital holographic microscopy.
Kaiser, M., Pohl, L., Ketelhut, S., Kastl, L., Gorzelanny, C., Götte, M., Schnekenburger, J., Goycoolea, F.M. and Kemper, B.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ.
Kalasova, I., Hanzlikova, H., Gupta, N., Li, Y., Altmüller, J., Reynolds, J.J., Stewart, G.S., Wollnik, B., Yigit, G. and Caldecott, K.W.
Neurology Genetics 5
(2): e320.
April 2019
Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined.
Kaleviste, E., Saare, M., Leahy, T.R., Bondet, V., Duffy, D., Mogensen, T., Jørgensen, S.E., Nurm, H., Ip, W., Davies, E.G., Sauer, S., Syvänen, A.C., Milani, L., Peterson, P. and Kisand, K.
European Journal of Immunology 49
(5): 790-800.
May 2019
Left prefrontal high-frequency rTMS may improve movement disorder in schizophrenia patients with predominant negative symptoms - a secondary analysis of a sham-controlled, randomized multicenter trial.
Kamp, D., Engelke, C., Wobrock, T., Wölwer, W., Winterer, G., Schmidt-Kraepelin, C., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Raees, A., Honer, W.G., Malchow, B., Schneider-Axmann, T., Falkai, P., Hasan, A. and Cordes, J.
Schizophrenia Research 204
: 445-447.
February 2019
Hypertonicity-affected genes are differentially expressed in clear cell renal cell carcinoma and correlate with cancer-specific survival.
Kandabarau, S., Leiz, J., Krohn, K., Winter, S., Bedke, J., Schwab, M., Schaeffeler, E. and Edemir, B.
Cancers 12
(1): 6.
18 December 2019
The association between frailty and MRI features of cerebral small vessel disease.
Kant, I.M.J., Mutsaerts, H.J.M.M., van Montfort, S.J.T., Jaarsma-Coes, M.G., Witkamp, T.D., Winterer, G., Spies, C.D., Hendrikse, J., Slooter, A.J.C. and de Bresser, J.
Scientific Reports 9
(1): 11343.
5 August 2019
Mathematical modeling of semiconductors: from quantum mechanics to devices.
Kantner, M., Mielke, A., Mittnenzweig, M. and Rotundo, N.
In: Joint CIM-WIAS Workshop, TAAO 2017, 6-8 Dec 2017, Lisbon, Portugal.
28 November 2019
MTrack: automated detection, tracking, and analysis of dynamic microtubules.
Kapoor, V., Hirst, W.G., Hentschel, C., Preibisch, S. and Reber, S.
Scientific Reports 9
(1): 3794.
7 March 2019
Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling.
Karabacak Calviello, A., Hirsekorn, A., Wurmus, R., Yusuf, D. and Ohler, U.
Genome Biology 20
(1): 42.
21 February 2019
Biallelic variant in AGTPBP1 causes infantile lower motor neuron degeneration and cerebellar atrophy.
Karakaya, M., Paketci, C., Altmueller, J., Thiele, H., Hoelker, I., Yis, U. and Wirth, B.
American Journal of Medical Genetics Part A 179
(8): 1580-1584.
August 2019
Recruitment of histone methyltransferase Ehmt1 to Foxp3 TSDR counteracts differentiation of induced regulatory T cells.
Karl, M., Sommer, C., Gabriel, C.H., Hecklau, K., Venzke, M., Hennig, A.F., Radbruch, A., Selbach, M. and Baumgrass, R.
Journal of Molecular Biology 431
(19): 3606-3625.
6 September 2019
Lyophilization of synthetic gene carriers.
Kasper, J.C., Hedtrich, S. and Friess, W.
Methods in Molecular Biology 1943
(2): 211-225.
2019
Vinylphosphonites for staudinger-induced chemoselective peptide cyclization and functionalization.
Kasper, M.A, Glanz, M., Oder, A., Schmieder, P., von Kries, J.P. and Hackenberger, C.P.R.
Chemical Science 10
(25): 6322-6329.
7 July 2019
Automatic quality evaluation as assessment standard for optical coherence tomography.
Kauer, J., Gawlik, K., Zimmermann, H.G., Kadas, E.M., Bereuter, C., Paul, F., Brandt, A.U., Hausser, F. and Beckers, I.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, United States.
26 February 2019
Impact of brief prewarming on anesthesia-related core-temperature drop, hemodynamics, microperfusion and postoperative ventilation in cytoreductive surgery of ovarian cancer: a randomized trial.
Kaufner, L., Niggemann, P., Baum, T., Casu, S., Sehouli, J., Bietenbeck, A., Boschmann, M., Spies, C.D., Henkelmann, A. and von Heymann, C.
BMC Anesthesiology 19
(1): 161.
22 August 2019
HSPA6: s new autosomal recessive candidate gene for the VATER/VACTERL malformation spectrum.
Kause, F., Zhang, R., Ludwig, M., Schmiedeke, E., Rissmann, A., Thiele, H., Altmueller, J., Herms, S., Hilger, A.C., Hildebrandt, F. and Reutter, H.
Birth Defects Research 111
(10): 591-597.
1 June 2019
Role of ryanodine type 2 receptors in elementary Ca(2+) signaling in arteries and vascular adaptive responses.
Kaßmann, M., Szijártó, I.A., García-Prieto, C.F., Fan, G., Schleifenbaum, J., Anistan, Y.M., Tabeling, C., Shi, Y., le Noble, F., Witzenrath, M., Huang, Y., Markó, L., Nelson, M.T. and Gollasch, M.
Journal of the American Heart Association 8
(9): e010090.
7 May 2019
Systems biology approach to study cancer metabolism.
Kempa, S. and Royla, N.
In:
Encyclopedia of Cancer.
Elsevier / Academic Press, 426-428.
ISBN 978-0-12-812485-7
2019
Quantitative phase imaging-based concepts for the analysis of global morphology changes in confluent cell layers.
Kemper, B., Pohl, L., Kaiser, M., Doepker, E., Schnekenburger, J. and Ketelhut, S.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
4 March 2019
Label-free detection of global morphology changes in confluent cell layers utilizing quantitative phase imaging with digital holographic microscopy.
Kemper, B., Pohl, L., Kaiser, M., Döpker, E., Schnekenburger, J. and Ketelhut, S.
In: European Conferences on Biomedical Optics 2019, 26-27 Jun 2019, Munich, Germany.
22 July 2019
Hyperkaliämie - Ursachen, Diagnostik und Therapie [Hyperkalemia - causes, diagnostic evaluation and treatment].
Kettritz, R.
Deutsche Medizinische Wochenschrift 144
(03): 180-184.
February 2019
Seltene Elektrolytstörungen [Rare electrolyte disorders].
Kettritz, R. and Luft, F.C.
Nephrologe 14
(2): 94-99.
March 2019
The incidence of acute kidney injury and associated hospital mortality: a retrospective cohort study of over 100 000 patients at Berlin's Charité Hospital.
Khadzhynov, D., Schmidt, D., Hardt, J., Rauch, G., Gocke, P., Eckardt, K.U. and Schmidt-Ott, K.M.
Deutsches Aerzteblatt International 116
(22): 397-404.
31 May 2019
Histological and functional comparisons of four anatomical regions of porcine skin with human abdominal skin.
Khiao In, M., Richardson, K.C., Loewa, A., Hedtrich, S., Kaessmeyer, S. and Plendl, J.
Anatomia Histologia Embryologia 48
(3): 207-217.
May 2019
Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism.
Kim, H.G., Rosenfeld, J.A., Scott, D.A., Bénédicte, G., Labonne, J.D., Brown, J., McGuire, M., Mahida, S., Naidu, S., Gutierrez, J., Lesca, G., des Portes, V., Bruel, A.L., Sorlin, A., Xia, F., Capri, Y., Muller, E., McKnight, D., Torti, E., Rüschendorf, F., Hummel, O., Islam, Z., Kolatkar, P.R., Layman, L.C., Ryu, D., Kong, I.K., Madan-Khetarpal, S. and Kim, C.H.
Molecular Autism 10
: 35.
22 October 2019
Biobanking for metabolomics and lipidomics in precision medicine.
Kirwan, J.A., Kaddurah-Daouk, R., Mitchell, T., Pischon, T., Schmidt, M.A. and Velagapudi, V.
Clinical Chemistry 65
(7): 827-832.
28 June 2019
A protocol for laser microdissection (LMD) followed by transcriptome analysis of plant reproductive tissue in phylogenetically distant angiosperms.
Kivivirta, K., Herbert, D., Lange, M., Beuerlein, K., Altmüller, J. and Becker, A.
Plant Methods 15
: 151.
16 December 2019
Quantitative grip force assessment of muscular weakness in chronic inflammatory demyelinating polyneuropathy.
Klehmet, J., Beutner, S., Hoffmann, S., Dornauer, M., Paul, F., Reilmann, R., Brandt, A.U. and Meisel, A.
BMC Neurology 19
(1): 118.
8 June 2019
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor.
Klein, S., Kleine, C.E., Pieper, A., Granzow, M., Gautsch, S., Himmit, M., Kahrmann, K., Schierwagen, R., Uschner, F.E., Magdaleno, F., Naoum, M.E., Kristiansen, Glen, Walther, T., Bader, M., Sauerbruch, T. and Trebicka, J.
Scientific Reports 9
(1): 11598.
12 August 2019
Dynamics of chromatin and transcription during transient depletion of the RSC chromatin remodeling complex.
Klein-Brill, A., Joseph-Strauss, D., Appleboim, A. and Friedman, N.
Cell Reports 26
(1): 279-292.
2 January 2019
Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice.
Klocke, J., Ulu, A., Wu, K., Rudolph, B., Dragun, D., Gollasch, M., Schunck, W.H., Hammock, B.D., Riemekasten, G. and Enghard, P.
Scientific Reports 9
(1): 8993.
20 June 2019
m(6)A-mRNA methylation regulates cardiac gene expression and cellular growth.
Kmietczyk, V., Riechert, E., Kalinski, L., Boileau, E., Malovrh, E., Malone, B., Gorska, A., Hofmann, C., Varma, E., Jürgensen, L., Kamuf-Schenk, V., Altmüller, J., Tappu, R., Busch, M., Most, P., Katus, H.A., Dieterich, C. and Völkers, M.
Life Science Alliance 2
(2): e201800233.
April 2019
Interferon-γ receptor signaling in dendritic cells restrains spontaneous proliferation of CD4(+) T cells in chronic lymphopenic mice.
Knop, L., Frommer, C., Stoycheva, D., Deiser, K., Kalinke, U., Blankenstein, T., Kammertoens, T., Dunay, I.R. and Schüler, T.
Frontiers in Immunology 10
: 140.
7 February 2019
Ninjurin1 regulates striated muscle growth and differentiation.
Kny, M., Csályi, K.D., Klaeske, K., Busch, K., Meyer, A.M., Merks, A.M., Darm, K., Dworatzek, E., Fliegner, D., Baczko, I., Regitz-Zagrosek, V., Butter, C., Luft, F.C., Panáková, D. and Fielitz, J.
PLoS ONE 14
(5): e0216987.
15 May 2019
Design and characterization of dietary assessment in the German National Cohort.
Knüppel, S., Clemens, M., Conrad, J., Gastell, S., Michels, K.B., Leitzmann, M., Krist, L., Pischon, T., Krause, G., Ahrens, W., Ebert, N., Jöckel, K.H., Kluttig, A., Obi, N., Kaaks, R., Lieb, W., Schipf, S., Brenner, H., Heuer, T., Harttig, U., Linseisen, J., Nöthlings, U. and Boeing, H.
European Journal of Clinical Nutrition 73
(11): 1480-1491.
November 2019
Cognitive impairment is associated with absolute intraoperative frontal α-band power but not with baseline α-band power: a pilot study.
Koch, S., Feinkohl, I., Chakravarty, S., Windmann, V., Lichtner, G., Pischon, T., Brown, E.N. and Spies, C.
Dementia and Geriatric Cognitive Disorders 48
: 1-2.
December 2019
Biallelic mutation in MYH7 and MYBPC3 leads to severe cardiomyopathy with left ventricular noncompaction phenotype.
Kolokotronis, K., Kühnisch, J., Klopocki, E., Dartsch, J., Rost, S., Huculak, C., Mearini, G., Störk, S., Carrier, L., Klaassen, S. and Gerull, B.
Human Mutation 40
(8): 1101-1114.
August 2019
Rare variants in BNC2 are implicated in autosomal-dominant congenital lower urinary-tract obstruction.
Kolvenbach, C.M., Dworschak, G.C., Frese, S., Japp, A.S., Schuster, P., Wenzlitschke, N., Yilmaz, Ö., Lopes, F.M., Pryalukhin, A., Schierbaum, L., van der Zanden, L.F.M., Kause, F., Schneider, R., Taranta-Janusz, K., Szczepańska, M., Pawlaczyk, K., Newman, W.G., Beaman, G.M., Stuart, H.M., Cervellione, R.M., Feitz, W.F.J., van Rooij, I.A.L.M., Schreuder, M.F., Steffens, M., Weber, S., Merz, W.M., Feldkötter, M., Hoppe, B., Thiele, H., Altmüller, J., Berg, C., Kristiansen, G., Ludwig, M., Reutter, H., Woolf, A.S., Hildebrandt, F., Grote, P., Zaniew, M., Odermatt, B. and Hilger, A.C.
American Journal of Human Genetics 104
(5): 994-1006.
2 May 2019
Renal fibrosis, immune cell infiltration and changes of TRPC channel expression after unilateral ureteral obstruction in Trpc6-/- mice.
Kong, W., Haschler, T.N., Nürnberg, B., Krämer, S., Gollasch, M. and Markó, L.
Cellular Physiology and Biochemistry 52
(6): 1484-1502.
2019
Prediction of circulating adipokine levels based on body fat compartments and adipose tissue gene expression.
Konigorski, S., Janke, J., Drogan, D., Bergmann, M.M., Hierholzer, J., Kaaks, R., Boeing, H. and Pischon, T.
Obesity Facts 12
(6): 590-605.
December 2019
The ARTS of cell death.
Koren, E. and Fuchs, Y.
Journal of Cell Death 12
: 1179066019836967.
1 January 2019
Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.
Kosciuczuk, E.M., Mehrotra, S., Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D., Fish, E.N., Vassilopoulos, A. and Platanias, L.C.
Journal of Biological Chemistry 294
(3): 827-837.
18 January 2019
MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis.
Kotelnikova, E., Kiani, N.A., Messinis, D., Pertsovskaya, I., Pliaka, V., Bernardo-Faura, M., Rinas, M., Vila, G., Zubizarreta, I., Pulido-Valdeolivas, I., Sakellaropoulos, T., Faigle, W., Silberberg, G., Masso, M., Stridh, P., Behrens, J., Olsson, T., Martin, R., Paul, F., Alexopoulos, L.G., Saez-Rodriguez, J., Tegner, J. and Villoslada, P.
Proceedings of the National Academy of Sciences of the United States of America 116
(19): 9671-9676.
7 May 2019
Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.
Kretschmann, S., Herda, S., Bruns, H., Russ, J., van der Meijden, E.D., Schlötzer-Schrehardt, U., Griffioen, M., Na, I.K., Mackensen, A. and Kremer, A.N.
Journal of Clinical Investigation 129
(7): 2952-2963.
1 July 2019
Less is more - estimation of the number of strides required to assess gait variability in spatially confined settings.
Kroneberg, D., Elshehabi, M., Meyer, A.C., Otte, K., Doss, S., Paul, F., Nussbaum, S., Berg, D., Kühn, A.A., Maetzler, W. and Schmitz-Hübsch, T.
Frontiers in Aging Neuroscience 10
: 435.
21 January 2019
A curated resource for phosphosite-specific signature analysis.
Krug, K., Mertins, P., Zhang, B., Hornbeck, P., Raju, R., Ahmad, R., Szucs, M., Mundt, F., Forestier, D., Jane-Valbuena, J., Keshishian, H., Gillette, M.A., Tamayo, P., Mesirov, J.P., Jaffe, J.D., Carr, S.A. and Mani, D.R.
Molecular & Cellular Proteomics 18
(3): 576-593.
1 March 2019
AltamISA: a Python API for ISA-Tab files.
Kuhring, M., Nieminen, M., Kirwan, J., Beule, D. and Holtgrewe, M.
Journal of Open Source Software 4
(40): 1610.
20 August 2019
Cardiac magnetic resonance stress perfusion imaging for evaluation of patients with chest pain.
Kwong, R.Y., Ge, Y., Steel, K., Bingham, S., Abdullah, S., Fujikura, K., Wang, W., Pandya, A., Chen, Y.Y., Mikolich, J.R., Boland, S., Arai, A.E., Bandettini, W.P., Shanbhag, S.M., Patel, A.R., Narang, A., Farzaneh-Far, A., Romer, B., Heitner, J.F., Ho, J.Y., Singh, J., Shenoy, C., Hughes, A., Leung, S.W., Marji, M., Gonzalez, J.A., Mehta, S., Shah, D.J., Debs, D., Raman, S.V., Guha, A., Ferrari, V.A., Schulz-Menger, J., Hachamovitch, R., Stuber, M. and Simonetti, O.P.
Journal of the American College of Cardiology 74
(14): 1741-1755.
8 October 2019
Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3.
Kühnisch, J., Herbst, C., Al-Wakeel-Marquard, N., Dartsch, J., Holtgrewe, M., Baban, A., Mearini, G., Hardt, J., Kolokotronis, K., Gerull, B., Carrier, L., Beule, D., Schubert, S., Messroghli, D., Degener, F., Berger, F. and Klaassen, S.
Clinical Genetics 96
(6): 549-559.
December 2019
L
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche, C.C., Henderson, R., Hsu, A., Behrens, S., Chen, X., Zhou, T., Wiehe, K., Saunders, K.O., Alam, S.M., Bonsignori, M., Borgnia, M.J., Sattentau, Q.J., Eaton, A., Greene, K., Gao, H., Liao, H.X., Williams, W.B., Peacock, J., Tang, H., Perez, L.G., Edwards, R.J., Kepler, T.B., Korber, B.T., Kwong, P.D., Mascola, J.R., Acharya, P., Haynes, B.F. and Montefiori, D.C.
PLoS Pathogens 15
(9): e1008026.
17 September 2019
Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat.
Labi, V., Peng, S., Klironomos, F., Munschauer, M., Kastelic, N., Chakraborty, T., Schoeler, K., Derudder, E., Martella, M., Mastrobuoni, G., Hernandez-Miranda, L.R., Lahmann, I., Kocks, C., Birchmeier, C., Kempa, S., Quintanilla-Martinez de Fend, L., Landthaler, M., Rajewsky, N. and Rajewsky, K.
Genes & Development 33
: 23-24.
7 November 2019
Cerebral microbleeds are not associated with postoperative delirium and postoperative cognitive dysfunction in older individuals.
Lachmann, G., Kant, I., Lammers, F., Windmann, V., Spies, C., Speidel, S., Borchers, F., Hadzidiakos, D., Hendrikse, J., Winterer, G. and de Bresser, J.
PLoS ONE 14
(6): e0218411.
14 June 2019
The accumulation of deficits approach to describe frailty.
Lachmann, R., Stelmach-Mardas, M., Bergmann, M.M., Bernigau, W., Weber, D., Pischon, T. and Boeing, H.
PLoS ONE 14
(10): e0223449.
15 October 2019
Impact of diabetic stress conditions on renal cell metabolome.
Lagies, S., Pichler, R., Bork, T., Kaminski, M.M., Troendle, K., Zimmermann, S., Huber, T.B., Walz, G., Lienkamp, S.S. and Kammerer, B.
Cells 8
(10): 1141.
24 September 2019
Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.
Lahmann, I., Bröhl, D., Zyrianova, T., Isomura, A., Czajkowski, M.T., Kapoor, V., Griger, J., Ruffault, P.L., Mademtzoglou, D., Zammit, P.S., Wunderlich, T., Spuler, S., Kühn, R., Preibisch, S., Wolf, J., Kageyama, R. and Birchmeier, C.
Genes & Development 33
(9-10): 524-535.
1 May 2019
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.
Lahrouchi, N., George, A., Ratbi, I., Schneider, R., Elalaoui, S.C., Moosa, S., Bharti, S., Sharma, R., Abu-Asab, M., Onojafe, F., Adadi, N., Lodder, E.M., Laarabi, F.Z., Lamsyah, Y., Elorch, H., Chebbar, I., Postma, A.V., Lougaris, V., Plebani, A., Altmueller, J., Kyrieleis, H., Meiner, V., McNeill, H., Bharti, K., Lyonnet, S., Wollnik, B., Henrion-Caude, A., Berraho, A., Hildebrandt, F., Bezzina, C.R., Brooks, B.P. and Sefiani, A.
Nature Communications 10
(1): 1180.
12 March 2019
Collagen I-based scaffolds negatively impact fracture healing in a mouse-osteotomy-model although used routinely in research and clinical application.
Lang, A., Kirchner, M., Stefanowski, J., Durst, M., Weber, M.C., Pfeiffenberger, M., Damerau, A., Hauser, A.E., Hoff, P., Duda, G.N., Buttgereit, F., Schmidt-Bleek, K. and Gaber, T.
Acta Biomaterialia 86
: 171-184.
1 March 2019
Direct zinc finger protein persulfidation by H(2)S is facilitated by Zn(2+).
Lange, M., Ok, K., Shimberg, G.D., Bursac, B., Markó, L., Ivanović-Burmazović, I., Michel, S. and Filipovic, M.R.
Angewandte Chemie International Edition 58
(24): 7997-8001.
11 June 2019
Cardiovascular programming during and after diabetic pregnancy: role of placental dysfunction and IUGR.
Langmia, I.M., Kräker, K., Weiss, S.E., Haase, N., Schütte, T., Herse, F. and Dechend, R.
Frontiers in Endocrinology 10
: 215.
April 2019
Longitudinal assessment of clonal mosaicism in human hematopoiesis via mitochondrial mutation tracking.
Lareau, C.A., Ludwig, L.S. and Sankaran, V.G.
Blood Advances 3
(24): 4161-4165.
23 December 2019
Social networks and protest participation: evidence from 130 million Twitter users.
Larson, J.M., Nagler, J., Ronen, J. and Tucker, J.A.
American Journal of Political Science 63
(3): 690-705.
July 2019
Allergy and atopy from infancy to adulthood: messages from the German birth cohort MAS.
Lau, S., Matricardi, P.M., Wahn, U., Lee, Y.A. and Keil, T.
Annals of Allergy, Asthma & Immunology 122
(1): 25-32.
January 2019
Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells.
Le, T.T.H., Tran, N.T., Dao, T.M.L., Nguyen, D.D., Do, H.D., Ha, T.L., Kühn, R., Nguyen, T.L., Rajewsky, K. and Chu, V.T.
Frontiers in Genetics 10
: 625.
July 2019
Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.
Lee, A.Y.L., Dubois, C.L., Sarai, K., Zarei, S., Schaeffer, D.F., Sander, M. and Kopp, J. L.
Gut 68
(3): 487-498.
March 2019
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
Lee, J., Termglinchan, V., Diecke, S., Itzhaki, I., Lam, C.K., Garg, P., Lau, E., Greenhaw, M., Seeger, T., Wu, H., Zhang, J.Z, Chen, X., Gil, I.P., Ameen, M., Sallam, K., Rhee, J.W., Churko, J.M., Chaudhary, R., Chour, T., Wang, P.J., Snyder, M.P., Chang, H.Y., Karakikes, I. and Wu, J.C.
Nature 572
(7769): 335-340.
15 August 2019
The dynamic nature of senescence in cancer.
Lee, S. and Schmitt, C.A.
Nature Cell Biology 21
(1): 94-101.
January 2019
FLAM-seq: full-length mRNA sequencing reveals principles of poly(A) tail length control.
Legnini, I., Alles, J., Karaiskos, N., Ayoub, S. and Rajewsky, N.
Nature Methods 16
(9): 879-886.
September 2019
Schwere Azidose: Differenzialdiagnostik und Therapie [Severe acidosis: differential diagnostics and treatment].
Lehner, L.J., Oppert, M. and Kettritz, R.
Nephrologe 14
(6): 431-437.
November 2019
Subtomogram averaging from cryo-electron tomograms.
Leigh, K.E., Navarro, P.P., Scaramuzza, S., Chen, W., Zhang, Y., Castaño-Díez, D. and Kudryashev, M.
Methods in Cell Biology 152
: 217-259.
2019
The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.
Leisegang, M.S., Gu, L., Preussner, J., Günther, S., Hitzel, J., Ratiu, C., Weigert, A., Chen, W., Schwarz, E.C., Looso, M., Fork, C. and Brandes, R.P.
FEBS Letters 593
(5): 487-498.
March 2019
Intestinal-cell kinase and juvenile myoclonic epilepsy.
Lerche, H., Berkovic, S.F. and Lowenstein, D.H.
New England Journal of Medicine 380
(16): e24.
18 April 2019
Using SMOG 2 to simulate complex biomolecular assemblies.
Levi, M., Bandarkar, P., Yang, H., Wang, A., Mohanty, U., Noel, J.K. and Whitford, P.C.
Methods in Molecular Biology 2022
: 129-151.
2019
Studying ribosome dynamics with simplified models.
Levi, M., Noel, J.K. and Whitford, P.C.
Methods 162-163
: 128-140.
1 June 2019
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial.
Levin, J., Maaß, S., Schuberth, M., Giese, A., Oertel, W.H., Poewe, W., Trenkwalder, C., Wenning, G.K., Mansmann, U., Südmeyer, M., Eggert, K., Mollenhauer, B., Lipp, A., Löhle, M., Classen, J., Münchau, A., Kassubek, J., Gandor, F., Berg, D., Egert-Schwender, S., Eberhardt, C., Paul, F., Bötzel, K., Ertl-Wagner, B., Huppertz, H.J., Ricard, I. and Höglinger, G.U.
Lancet Neurology 18
(8): 724-735.
August 2019
The Tug1 locus is essential for male fertility.
Lewandowski, J.P., Dumbović, G., Watson, A.R., Hwang, T., Jacobs-Palmer, E., Chang, N., Much, C., Turner, K., Kirby, C., Schulz, J.F., Müller, C.L., Rubinstein, N.D., Groff, A.F., Liapis, S.C., Gerhardinger, C., Hubner, N., van Heesch, S., Hoekstra, H.E., Sauvageau, M. and Rinn, J.L.
bioRxiv
: 562066.
28 February 2019
Pathophysiological role of caveolae in hypertension.
Lian, X., Matthaeus, C., Kaßmann, M., Daumke, O. and Gollasch, M.
Frontiers in Medicine 6
: 153.
July 2019
Mapping the MHC class I spliced immunopeptidome of cancer cells.
Liepe, J., Sidney, J., Lorenz, F.K.M., Sette, A. and Mishto, M.
Cancer Immunology Research 7
(1): 62-76.
January 2019
Deubiquitinase USP10 regulates Notch signaling in the endothelium.
Lim, R., Sugino, T., Nolte, H., Andrade, J., Zimmermann, B., Shi, C., Doddaballapur, A., Ong, Y.T., Wilhelm, K., Fasse, J.W.D., Ernst, A., Kaulich, M., Husnjak, K., Boettger, T., Guenther, S., Braun, T., Krüger, M., Benedito, R., Dikic, I. and Potente, M.
Science 364
(6436): 188-193.
12 April 2019
Angiotensin II type 2 receptor mediates high fat diet-induced cardiomyocyte hypertrophy and hypercholesterolemia.
Lima, V.M., Lino, C.A., Senger, N., de Oliveira Silva, T., Fonseca, R.I.B., Bader, M., Santos, R.A.S., Júnior, JD., Barreto-Chaves, M.L.M. and Diniz, G.P.
Molecular and Cellular Endocrinology 498
: 110576.
1 December 2019
Unknown mutations and genotype/phenotype correlations of autosomal recessive congenital ichthyosis in patients from Saudi Arabia and Pakistan.
Lima Cunha, D., Alakloby, O.M., Gruber, R., Kakar, N., Ahmad, J., Alawbathani, S., Plank, R., Eckl, K., Krabichler, B., Altmüller, J., Nürnberg, P., Zschocke, J., Borck, G., Schmuth, M., Alabdulkareem, A.S., Abdulaziz Alnutaifi, K. and Hennies, H.C.
Molecular Genetics & Genomic Medicine 7
(3): e539.
March 2019
Calcyphosine-like (CAPSL) is regulated in multiple symmetric lipomatosis and is involved in adipogenesis.
Lindner, A., Marbach, F., Tschernitz, S., Ortner, C., Berneburg, M., Felthaus, O., Prantl, L., Kye, M.J., Rappl, G., Altmüller, J., Thiele, H., Schreml, S. and Schreml, J.
Scientific Reports 9
(1): 8444.
11 June 2019
Clinical relevance of circulating MACC1 and S100A4 transcripts for ovarian cancer.
Link, T., Kuhlmann, J.D., Kobelt, D., Herrmann, P., Vassileva, Y., Kramer, M., Frank, K., Göckenjan, M., Wimberger, P. and Stein, U.
Molecular Oncology 13
(5): 1268-1279.
May 2019
Endothelial B2-receptor overexpression as an alternative animal model for hereditary angioedema.
Lopes Veronez, C., Maghsodi, S., Todiras, M., Popova, E., Rodrigues, A.F., Qadri, F., Pesquero, J.B. and Bader, M.
Allergy 74
(10): 1998-2002.
October 2019
Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.
Lorenz, M., Blaschke, B., Benn, A., Hammer, E., Witt, E., Kirwan, J., Fritsche-Guenther, R., Gloaguen, Y., Bartsch, C., Vietzke, A., Kramer, F., Kappert, K., Brunner, P., Nguyen, H.G., Dreger, H., Stangl, K., Knaus, P. and Stangl, V.
Atherosclerosis 291
: 99-106.
December 2019
Corrections of myocardial tissue sodium concentration measurements in human cardiac (23)Na MRI at 7 Tesla.
Lott, J., Platt, T., Niesporek, S.C., Paech, D., Behl, N.G.R., Niendorf, T., Bachert, P., Ladd, M.E. and Nagel, A.M.
Magnetic Resonance in Medicine 82
(1): 159-173.
July 2019
Diversity in the lab makes me a better scientist.
Lowenstein, E.
Scientific American 320
(1): 8.
January 2019
Transcriptional states and chromatin accessibility underlying human erythropoiesis.
Ludwig, L.S., Lareau, C.A., Bao, E.L., Nandakumar, S.K., Muus, C., Ulirsch, J.C., Chowdhary, K., Buenrostro, J.D., Mohandas, N., An, X., Aryee, M.J., Regev, A. and Sankaran, V.G.
Cell Reports 27
(11): 3228-3240.
11 June 2019
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics.
Ludwig, L.S., Lareau, C.A., Ulirsch, J.C., Christian, E., Muus, C., Li, L.H., Pelka, K., Ge, W., Oren, Y., Brack, A., Law, T., Rodman, C., Chen, J.H., Boland, G.M., Hacohen, N., Rozenblatt-Rosen, O., Aryee, M.J., Buenrostro, J.D., Regev, A. and Sankaran, V.G.
Cell 176
(6): 1325-1339.
7 March 2019
Genome-wide analysis of RNA and protein localization and local translation in mESC-derived neurons.
Ludwik, K.A., von Kuegelgen, N. and Chekulaeva, M.
Methods 162-163
: 31-41.
June 2019
Men, mice, and blood pressure: telemetry?
Luft, F.C.
Kidney International 96
(1): 31-33.
July 2019
Combined analysis of metabolomes, proteomes, and transcriptomes of hepatitis C virus-infected cells and liver to identify pathways associated with disease development.
Lupberger, J., Croonenborghs, T., Roca Suarez, A.A., Van Renne, N., Jühling, F., Oudot, M.A., Virzì, A., Bandiera, S., Jamey, C., Meszaros, G., Brumaru, D., Mukherji, A., Durand, S.C., Heydmann, L., Verrier, E.R., El Saghire, H., Hamdane, N., Bartenschlager, R., Fereshetian, S., Ramberger, E., Sinha, R., Nabian, M., Everaert, C., Jovanovic, M., Mertins, P., Carr, S.A., Chayama, K., Dali-Youcef, N., Ricci, R., Bardeesy, N.M., Fujiwara, N., Gevaert, O., Zeisel, M.B., Hoshida, Y., Pochet, N. and Baumert, T.F.
Gastroenterology 157
(2): 537-551.
August 2019
M
Prohibitin promotes dedifferentiation and is a potential therapeutic target in neuroblastoma.
MacArthur, I.C., Bei, Y., Garcia, H.D., Ortiz, M.V., Toedling, J., Klironomos, F., Rolff, J., Eggert, A., Schulte, J.H., Kentsis, A. and Henssen, A.G.
JCI Insight 4
(10): e127130.
16 May 2019
Microtubule cytoskeleton regulates connexin 43 localization and cardiac conduction in cardiomyopathy caused by mutation in A-type lamins gene.
Macquart, C., Jüttner, R., Le Dour, C., Chatzifrangkeskou, M., Schmitt, A., Gotthardt, M., Bonne, G. and Muchir, A.
Human Molecular Genetics 28
(24): 4043-4052.
15 December 2019
Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus.
Maggiolini, F.A.M., Cantsilieris, S., D'Addabbo, P., Manganelli, M., Coe, B.P., Dumont, B.L., Sanders, A.D., Pang, A.W.C., Vollger, M.R., Palumbo, O., Palumbo, P., Accadia, M., Carella, M., Eichler, E.E. and Antonacci, F.
PLoS Genetics 15
(3): e1008075.
27 March 2019
Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses.
Maglione, M., Kochlamazashvili, G., Eisenberg, T., Rácz, B., Michael, E., Toppe, D., Stumpf, A., Wirth, A., Zeug, A., Müller, F.E., Moreno-Velasquez, L., Sammons, R.P., Hofer, S.J., Madeo, F., Maritzen, T., Maier, N., Ponimaskin, E., Schmitz, D., Haucke, V. and Sigrist, S.J.
Scientific Reports 9
(1): 19616.
23 December 2019
The role of 17β-estradiol and estrogen receptors in regulation of Ca(2+) channels and mitochondrial function in cardiomyocytes.
Mahmoodzadeh, S. and Dworatzek, E.
Frontiers in Endocrinology 10
: 310.
May 2019
An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance.
Mai, K., Li, L., Wiegand, S., Brachs, M., Leupelt, V., Ernert, A., Kühnen, P., Hübner, N., Robinson, P., Chen, W., Krude, H. and Spranger, J.
Diabetes 68
(1): 57-65.
1 January 2019
Structure-based screening of tetrazolylhydrazide inhibitors versus KDM4 histone demethylases.
Malecki, P.H., Rueger, N., Roatsch, M., Krylova, O., Link, A., Jung, M., Heinemann, U. and Weiss, M.S.
ChemMedChem 14
(21): 1828-1839.
6 November 2019
SorCS2 controls functional expression of amino acid transporter EAAT3 and protects neurons from oxidative stress and epilepsy-induced pathology.
Malik, A.R., Szydlowska, K., Nizinska, K., Asaro, A., van Vliet, E.A., Popp, O., Dittmar, G., Fritsche-Guenther, R., Kirwan, J.A., Nykjaer, A., Lukasiuk, K., Aronica, E. and Willnow, T.E.
Cell Reports 26
(10): 2792-2804.
5 March 2019
Excitatory amino acid transporters in physiology and disorders of the central nervous system.
Malik, A.R. and Willnow, T.E.
International Journal of Molecular Sciences 20
(22): 5671.
12 November 2019
Impact of stable angina on health status and quality of life perception of currently treated patients. The BRIDGE 2 survey.
Manolis, A.J., Ambrosio, G., Collins, P., Dechend, R., Lopez-Sendon, J., Pegoraro, V. and Camm, A.J.
European Journal of Internal Medicine 70
: 60-67.
November 2019
The discovery of a LEMD2-associated nuclear envelopathy with early progeroid appearance suggests advanced applications for AI-driven facial phenotyping.
Marbach, F., Rustad, C.F., Riess, A., Đukić, D., Hsieh, T.C., Jobani, I., Prescott, T., Bevot, A., Erger, F., Houge, G., Redfors, M., Altmueller, J., Stokowy, T., Gilissen, C., Kubisch, C., Scarano, E., Mazzanti, L., Fiskerstrand, T., Krawitz, P.M., Lessel, D. and Netzer, C.
American Journal of Human Genetics 104
(4): 749-757.
4 April 2019
A new highly thyrotropin receptor-selective small molecule antagonist with potential for the treatment of Graves' orbitopathy.
Marcinkowski, P., Hoyer, I., Specker, E., Furkert, J., Rutz, C., Neuenschwander, M., Sobottka, S., Sun, H., Nazare, M., Berchner-Pfannschmidt, U., von Kries, J.P., Eckstein, A., Schülein, R. and Krause, G.
Thyroid 29
(1): 111-123.
23 January 2019
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7.
Marg, A., Escobar Fernandez, H., Karaiskos, N., Grunwald, S.A., Metzler, E., Kieshauer, J., Sauer, S., Pasemann, D., Malfatti, E., Mompoint, D., Quijano-Roy, S., Boltengagen, A., Schneider, J., Schülke, M., Kunz, S., Carlier, R., Birchmeier, C., Amthor, H., Spuler, A., Kocks, C., Rajewsky, N. and Spuler, S.
Nature Communications 10
(1): 5776.
18 December 2019
The author file: Stephan Preibisch.
Marx, V.
Nature Methods 16
(9): 793.
September 2019
Evolution of replication origins in vertebrate genomes: rapid turnover despite selective constraints.
Massip, F., Laurent, M., Brossas, C., Fernández-Justel, J.M., Gómez, M., Prioleau, M.N., Duret, L. and Picard, F.
Nucleic Acids Research 47
(10): 5114-5125.
4 June 2019
Targeting APLN/APLNR improves antiangiogenic efficiency and blunts proinvasive side effects of VEGFA/VEGFR2 blockade in glioblastoma.
Mastrella, G., Hou, M., Li, M., Stoecklein, V.M., Zdouc, N., Volmar, M.N.M., Miletic, H., Reinhard, S., Herold-Mende, C.C., Kleber, S., Eisenhut, K., Gargiulo, G., Synowitz, M., Vescovi, A.L., Harter, P.N., Penninger, J.M., Wagner, E., Mittelbronn, M., Bjerkvig, R., Hambardzumyan, D., Schüller, U., Tonn, J.C., Radke, J., Glass, R. and Kälin, R.E.
Cancer Research 79
(9): 2298-2313.
May 2019
eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization.
Matthaeus, C., Lian, X., Kunz, S., Lehmann, M., Zhong, C., Bernert, C., Lahmann, I., Müller, D.N., Gollasch, M. and Daumke, O.
PLoS ONE 14
(10): e0223620.
10 October 2019
Targeted manipulation of brain serotonin: RNAi-mediated knockdown of tryptophan hydroxylase 2 in rats.
Matthes, S., Mosienko, V., Popova, E., Rivalan, M., Bader, M. and Alenina, N.
ACS Chemical Neuroscience 10
(7): 3207-3217.
17 July 2019
A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs.
McCorkindale, A.L., Wahle, P., Werner, S., Jungreis, I., Menzel, P., Shukla, C.J., Abreu, R.L.P., Irizarry, R.A., Meyer, I.M., Kellis, M. and Zinzen, R.P.
Development 146
(6): dev175265.
28 March 2019
Long-term disability in neuromyelitis optica spectrum disorder with a history of myelitis is associated with age at onset, delay in diagnosis/preventive treatment, MRI lesion length and presence of symptomatic brain lesions.
Mealy, M.A., Mossburg, S.E., Kim, S.H., Messina, S., Borisow, N., Lopez-Gonzalez, R., Ospina, J.P., Scheel, M., Yeshokumar, A.K., Awad, A., Leite, M.I., Arango, J.A.J., Paul, F., Palace, J., Kim, H.J. and Levy, M.
Multiple Sclerosis and Related Disorders 28
: 64-68.
February 2019
Transcriptional dynamics of microRNAs and their targets during Drosophila neurogenesis.
Menzel, P., McCorkindale, A.L., Stefanov, S.R., Zinzen, R.P. and Meyer, I.M.
RNA Biology 16
(1): 69-81.
20 January 2019
BIQ: A method for searching circular RNAs in transcriptome databases by indexing backsplice junctions.
Menzel, P. and Meyer, I.M.
bioRxiv
: 556993.
25 February 2019
Targeted genomic integration of EGFP under tubulin beta 3 class III promoter and mEos2 under tryptophan hydroxylase 2 promoter does not produce sufficient levels of reporter gene expression.
Menzorov, A.G., Orishchenko, K.E., Fishman, V.S., Shevtsova, A.A., Mungalov, R.V., Pristyazhnyuk, I.E., Kizilova, E.A., Matveeva, N.M., Alenina, N., Bader, M., Rubtsov, N.B. and Serov, O.L.
Journal of Cellular Biochemistry 120
(10): 17208-17218.
October 2019
High-throughput screening for modulators of CFTR activity based on genetically engineered cystic fibrosis disease-specific iPSCs.
Merkert, S., Schubert, M., Olmer, R., Engels, L., Radetzki, S., Veltman, M., Scholte, B.J., Zöllner, J., Pedemonte, N., Galietta, L.J.V., von Kries, J.P. and Martin, U.
Stem Cell Reports 12
(6): 1389-1403.
11 June 2019
Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
Messal, H.A., Alt, S., Ferreira, R.M.M., Gribben, C., Wang, V.M.Y., Cotoi, C.G., Salbreux, G. and Behrens, A.
Nature 566
(7742): 126-130.
7 February 2019
Little Old Ladies' Eye.
Middeke, M., Nasemann, J. and Luft, F.C.
Artery Research
June 2019
Microbial abundance, activity and population genomic profiling with mOTUs2.
Milanese, A., Mende, D.R., Paoli, L., Salazar, G., Ruscheweyh, H.J., Cuenca, M., Hingamp, P., Alves, R., Costea, P.I., Coelho, L.P., Schmidt, T.S.B., Almeida, A., Mitchell, A.L., Finn, R.D., Huerta-Cepas, J., Bork, P., Zeller, G. and Sunagawa, S.
Nature Communications 10
(1): 1014.
4 March 2019
Mapping the lung.
Mildner, A. and Yona, S.
Science 363
(6432): 1154-1155.
15 March 2019
Nomenclature for cellular plasticity: are the terms as plastic as the cells themselves?
Mills, J.C., Stanger, B.Z. and Sander, M.
EMBO Journal 38
(19): e103148.
1 October 2019
Application of europium-doped very small iron oxide nanoparticles to visualize neuroinflammation with MRI and fluorescence microscopy.
Millward, J.M., de Schellenberger, A.A., Berndt, D., Hanke-Vela, L., Schellenberger, E., Waiczies, S., Taupitz, M., Kobayashi, Y., Wagner, S. and Infante-Duarte, C.
Neuroscience 403
: 136-144.
1 April 2019
Assessment of disease progression in dysferlinopathy: a 1-year cohort study.
Moore, U., Jacobs, M., James, M.K., Mayhew, A.G., Fernandez-Torron, R., Feng, J., Cnaan, A., Eagle, M., Bettinson, K., Rufibach, L.E., Lofra, R.M., Blamire, A.M., Carlier, P.G., Mittal, P., Lowes, L.P., Alfano, L., Rose, K., Duong, T., Berry, K.M., Montiel-Morillo, E., Pedrosa-Hernández, I., Holsten, S., Sanjak, M., Ashida, A., Sakamoto, C., Tateishi, T., Yajima, H., Canal, A., Ollivier, G., Decostre, V., Mendez, J.B., Sánchez-Aguilera Praxedes, N., Thiele, S., Siener, C., Shierbecker, J., Florence, J.M., Vandevelde, B., DeWolf, B., Hutchence, M., Gee, R., Prügel, J., Maron, E., Hilsden, H., Lochmüller, H., Grieben, U., Spuler, S., Tesi Rocha, C., Day, J.W., Jones, K.J., Bharucha-Goebel, D.X., Salort-Campana, E., Harms, M., Pestronk, A., Krause, S., Schreiber-Katz, O., Walter, M.C., Paradas, C., Hogrel, J.Y., Stojkovic, T., Takeda, S., Mori-Yoshimura, M., Bravver, E., Sparks, S., Díaz-Manera, J., Bello, L., Semplicini, C., Pegoraro, E., Mendell, J.R., Bushby, K. and Straub, V.
Neurology 92
(5): e461-e474.
29 January 2019
Autosomal-recessive mutations in MESD cause osteogenesis imperfecta.
Moosa, S., Yamamoto, G.L., Garbes, L., Keupp, K., Beleza-Meireles, A., Moreno, C.A., Valadares, E.R., de Sousa, S.B., Maia, S., Saraiva, J., Honjo, R.S., Kim, C.A., Cabral de Menezes, H., Lausch, E., Lorini, P.V., Lamounier, A., Carniero, T.C.B., Giunta, C., Rohrbach, M., Janner, M., Semler, O., Beleggia, F., Li, Y., Yigit, G., Reintjes, N., Altmüller, J., Nürnberg, P., Cavalcanti, D.P., Zabel, B., Warman, M.L., Bertola, D.R., Wollnik, B. and Netzer, C.
American Journal of Human Genetics 105
(4): 836-843.
3 October 2019
240th ENMC workshop: The involvement of skeletal muscle stem cells in the pathology of muscular dystrophies 25–27 January 2019, Hoofddorp, The Netherlands.
Morgan, J., Butler-Browne, G., Muntoni, F. and Patel, K.
Neuromuscular Disorders 29
(9): 704-715.
2019
Insights into pancreatic β cell energy metabolism using rodent β cell models.
Morten, K.J., Potter, M., Badder, L., Sivathondan, P., Dragovic, R., Neumann, A., Gavin, J., Shrestha, R., Reilly, S., Phadwal, K., Lodge, T.A., Borzychowski, A., Cookson, S., Mitchell, C., Morovat, A., Simon, A.K., Uusimaa, J., Hynes, J. and Poulton, J.
Wellcome Open Research 2
: 14.
25 September 2019
Characterization of mouse adult testicular macrophage populations by immunofluorescence imaging and flow cytometry.
Mossadegh-Keller, N. and Sieweke, M.H.
Bio-protocol 9
(5): e3178.
5 March 2019
A (3D-nuclear) space odyssey: making sense of Hi-C maps.
Mota-Gómez, I. and Lupiáñez, D.G.
Genes 10
(6): 415.
29 May 2019
Normative data and minimally detectable change for inner retinal layer thicknesses using a semi-automated OCT image segmentation pipeline.
Motamedi, S., Gawlik, K., Ayadi, N., Zimmermann, H.G., Asseyer, S., Bereuter, C., Mikolajczak, J., Paul, F., Kadas, E.M. and Brandt, A.U.
Frontiers in Neurology 10
: 1117.
November 2019
Proteomic and transcriptomic changes in hibernating grizzly bears reveal metabolic and signaling pathways that protect against muscle atrophy.
Mugahid, D.A., Sengul, T.G., You, X., Wang, Y., Steil, L., Bergmann, N., Radke, M.H., Ofenbauer, A., Gesell-Salazar, M., Balogh, A., Kempa, S., Tursun, B., Robbins, C.T., Völker, U., Chen, W., Nelson, L. and Gotthardt, M.
Scientific Reports 9
(1): 19976.
27 December 2019
Deciphering human ribonucleoprotein regulatory networks.
Mukherjee, N., Wessels, H.H., Lebedeva, S., Sajek, M., Ghanbari, M., Garzia, A., Munteanu, A., Yusuf, D., Farazi, T., Hoell, J.I., Akat, K.M., Akalin, A., Tuschl, T. and Ohler, U.
Nucleic Acids Research 47
(2): 570-581.
25 January 2019
Mutations in PIGB cause an inherited GPI biosynthesis defect with an axonal neuropathy and metabolic abnormality in severe cases.
Murakami, Y., Nguyen, T.T.M., Baratang, N., Raju, P.K., Knaus, A., Ellard, S., Jones, G., Lace, B., Rousseau, J., Ajeawung, N.F., Kamei, A., Minase, G., Akasaka, M., Araya, N., Koshimizu, E., van den Ende, J., Erger, F., Altmüller, J., Krumina, Z., Strautmanis, J., Inashkina, I., Stavusis, J., El-Gharbawy, A., Sebastian, J., Puri, R.D., Kulshrestha, S., Verma, I.C., Maier, E.M., Haack, T.B., Israni, A., Baptista, J., Gunning, A., Rosenfeld, J.A, Liu, P., Joosten, M., Rocha, M.E., Hashem, M.O., Aldhalaan, H.M., Alkuraya, F.S., Miyatake, S., Matsumoto, N., Krawitz, P.M., Rossignol, E., Kinoshita, T. and Campeau, P.M.
American Journal of Human Genetics 105
(2): 384-394.
1 August 2019
Sodium in the microenvironment regulates immune responses and tissue homeostasis.
Müller, D.N., Wilck, N., Haase, S., Kleinewietfeld, M. and Linker, R.A.
Nature Reviews Immunology 19
(4): 243-254.
April 2019
A multiple Piccolino-RIBEYE interaction supports plate-shaped synaptic ribbons in retinal neurons.
Müller, T.M., Gierke, K., Joachimsthaler, A., Sticht, H., Izsvák, Z., Hamra, F.K., Fejtová, A., Ackermann, F., Garner, C.C., Kremers, J., Brandstätter, J.H. and Regus-Leidig, H.
Journal of Neuroscience 39
(14): 2606-2619.
3 April 2019
The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans.
Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A. and Tursun, B.
Aging Cell 18
(6): e13012.
December 2019
N
Current clinical practice and challenges in the management of secondary immunodeficiency in hematological malignancies.
Na, I.K., Buckland, M., Agostini, C., Edgar, J.D.M., Friman, V., Michallet, M., Sánchez-Ramón, S., Scheibenbogen, C. and Quinti, I.
European Journal of Haematology 102
(6): 447-456.
June 2019
Magnetic resonance perfusion or fractional flow reserve in coronary disease.
Nagel, E., Greenwood, J.P., McCann, G.P., Bettencourt, N., Shah, A.M., Hussain, S.T., Perera, D., Plein, S., Bucciarelli-Ducci, C., Paul, M., Westwood, M.A., Marber, M., Richter, W.S., Puntmann, V.O., Schwenke, C., Schulz-Menger, J., Das, R., Wong, J., Hausenloy, D.J., Steen, H. and Berry, C.
New England Journal of Medicine 380
(25): 2418-2428.
20 June 2019
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
Nandakumar, S.K., McFarland, S.K., Mateyka, L.M., Lareau, C.A., Ulirsch, J.C., Ludwig, L.S., Agarwal, G., Engreitz, J.M., Przychodzen, B., McConkey, M., Cowley, G.S., Doench, J.G., Maciejewski, J.P., Ebert, B.L., Root, D.E. and Sankaran, V.G.
eLife 8
: e44080.
9 May 2019
Elektromagnetische Interferenz von aktiven Herzrhythmusimplantaten im Alltag und im beruflichen Umfeld: Stellungnahme der Deutschen Gesellschaft für Kardiologie (DGK) und der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin (DGAUM) [Electromagnetic interference of active cardiac rhythm implants in the daily routine and occupational environment: statement of the German Cardiac Society (DGK) and the German Society for Occupational and Environmental Medicine (DGAUM)].
Napp, A., Kolb, C., Lennerz, C., Bauer, W., Schulz-Menger, J., Kraus, T., Marx, N. and Stunder, D.
Kardiologe 13
(4): 216-235.
August 2019
Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
Nasri, M., Mir, P., Dannenmann, B., Amend, D., Skroblyn, T., Xu, Y., Schulze-Osthoff, K., Klimiankou, M., Welte, K. and Skokowa, J.
Blood Advances 3
(1): 63-71.
8 January 2019
Distinct subgroups in hypertrophic cardiomyopathy in the NHLBI HCM Registry.
Neubauer, S., Kolm, P., Ho, C.Y., Kwong, R.Y., Desai, M.Y., Dolman, S.F., Appelbaum, E., Desvigne-Nickens, P., DiMarco, J.P., Friedrich, M.G., Geller, N., Harper, A.R., Jarolim, P., Jerosch-Herold, M., Kim, D.Y., Maron, M.S., Schulz-Menger, J., Piechnik, S.K., Thomson, K., Zhang, C., Watkins, H., Weintraub, W.S. and Kramer, C.M.
Journal of the American College of Cardiology 74
(19): 2333-2345.
12 November 2019
Interplay of Na(+) balance and immunobiology of dendritic cells.
Neubert, P., Schröder, A., Müller, D.N. and Jantsch, J.
Frontiers in Immunology 10
: 599.
March 2019
HIF1A and NFAT5 coordinate Na(+)-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Neubert, P., Weichselbaum, A., Reitinger, C., Schatz, V., Schröder, A., Ferdinand, J.R., Simon, M., Bär, A.L., Brochhausen, C., Gerlach, R.G., Tomiuk, S., Hammer, K., Wagner, S., van Zandbergen, G., Binger, K.J., Müller, D.N., Kitada, K., Clatworthy, M.R., Kurts, C., Titze, J., Abdullah, Z. and Jantsch, J.
Autophagy 15
(11): 1899-1916.
November 2019
Human cardiac magnetic resonance at ultrahigh fields : technical innovations, early clinical applications and opportunities for discoveries.
Niendorf, T., Huelnhagen, T., Winter, L. and Paul, K.
In:
Cardiovascular magnetic resonance : a companion to Braunwald's heart disease.
Elsevier, Philadelphia, PA, 142-160.
ISBN 978-0-323-41561-3
2019
Assessment of genetic variant burden in epilepsy-associated brain lesions.
Niestroj, L.M., May, P., Artomov, M., Kobow, K., Coras, R., Pérez-Palma, E., Altmüller, J., Thiele, H., Nürnberg, P., Leu, C., Palotie, A., Daly, M.J., Klein, K.M., Beschorner, R., Weber, Y.G., Blümcke, I. and Lal, D.
European Journal of Human Genetics 27
(11): 1738-1744.
November 2019
Diagnosis of obesity and use of obesity biomarkers in science and clinical medicine.
Nimptsch, K., Konigorski, S. and Pischon, T.
Metabolism 92
: 61-70.
March 2019
SHP-2 in lymphocytes' cytokine and inhibitory receptor signaling.
Niogret, C., Birchmeier, W. and Guarda, G.
Frontiers in Immunology 10
: 2468.
25 October 2019
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret, C., Miah, S.M.S., Rota, G., Fonta, N.P., Wang, H., Held, W., Birchmeier, W., Sexl, V., Yang, W., Vivier, E., Ho, P.C., Brossay, L. and Guarda, G.
Nature Communications 10
(1): 1444.
29 March 2019
Gene expression cartography.
Nitzan, M., Karaiskos, N., Friedman, N. and Rajewsky, N.
Nature 576
(7785): 132-137.
5 December 2019
Polymer-like model to study the dynamics of dynamin filaments on deformable membrane tubes.
Noel, J.K., Noé, F., Daumke, O. and Mikhailov, A.S.
Biophysical Journal 117
(10): 1870-1891.
19 November 2019
Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: an international study.
Nolan, R.C., Liu, M., Akhand, O., Calabresi, P.A., Paul, F., Petzold, A., Balk, L., Brandt, A.U., Martínez-Lapiscina, E.H., Saidha, S., Villoslada, P., Abu Al-Hassan, A., Behbehani, R., Frohman, E.M., Frohman, T., Havla, J., Hemmer, B., Jiang, H., Knier, B., Korn, T., Leocani, L., Papadopoulou, A., Pisa, M., Zimmermann, H., Galetta, S.L. and Balcer, L.J.
Annals of Neurology 85
(5): 618-629.
May 2019
Placental CX3CL1 is deregulated by angiotensin II and contributes to a pro-inflammatory trophoblast-monocyte interaction.
Nonn, O., Güttler, J., Forstner, D., Maninger, S., Zadora, J., Balogh, A., Frolova, A., Glasner, A., Herse, F. and Gauster, M.
International Journal of Molecular Sciences 20
(3): 641.
2 February 2019
First person - Marcel Nowak and Benjamin Suenkel.
Nowak, M. and Suenkel, B.
Journal of Cell Science 132
(17): jcs237297.
September 2019
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
Nowak, M., Suenkel, B., Porras, P., Migotti, R., Schmidt, F., Kny, M., Zhu, X., Wanker, E.E., Dittmar, G., Fielitz, J. and Sommer, T.
Journal of Cell Science 132
(17): jcs233395.
6 September 2019
Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.
Numberger, D., Ganzert, L., Zoccarato, L., Mühldorfer, K., Sauer, S., Grossart, H.P. and Greenwood, A.D.
Scientific Reports 9
(1): 9673.
4 July 2019
O
Defining orphan conditions in the context of the European orphan regulation: challenges and evolution.
O'Connor, D.J., Sheean, M.E., Hofer, M.P., Tsigkos, S., Mariz, S., Fregonese, L., Larsson, K., Hivert, V., Westermark, K., Naumann-Winter, F., Stoyanova-Beninska, V., Barišić, I., Capovilla, G., Magrelli, A. and Sepodes, B.
Nature Reviews Drug Discovery 18
(7): 479-480.
July 2019
Age-related gliosis promotes central nervous system lymphoma through CCL19-mediated tumor cell retention.
O'Connor, T., Zhou, X., Kosla, J., Adili, A., Garcia Beccaria, M., Kotsiliti, E., Pfister, D., Johlke, A.L., Sinha, A., Sankowski, R., Schick, M., Lewis, R., Dokalis, N., Seubert, B., Höchst, B., Inverso, D., Heide, D., Zhang, W., Weihrich, P., Manske, K., Wohlleber, D., Anton, M., Hoellein, A., Seleznik, G., Bremer, J., Bleul, S., Augustin, H.G., Scherer, F., Koedel, U., Weber, A., Protzer, U., Förster, R., Wirth, T., Aguzzi, A., Meissner, F., Prinz, M., Baumann, B., Höpken, U.E., Knolle, P.A., von Baumgarten, L., Keller, U. and Heikenwalder, M.
Cancer Cell 36
(3): 250-267.
16 September 2019
SCelVis: Powerful explorative single cell data analysis on the desktop and in the cloud.
Obermayer, B., Holtgrewe, M., Nieminen, M., Messerschmidt, C. and Beule, D.
bioRxiv
: 713008.
24 July 2019
Left ventricular noncompaction: phenotype in an integrated model of cardiomyopathy?
Oechslin, E. and Klaassen, S.
Journal of the American College of Cardiology 73
(13): 1612-1615.
1 April 2019
Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study.
Oertel, F.C., Outteryck, O., Knier, B., Zimmermann, H., Borisow, N., Bellmann-Strobl, J., Blaschek, A., Jarius, S., Reindl, M., Ruprecht, K., Meinl, E., Hohlfeld, R., Paul, F., Brandt, A.U., Kümpfel, T. and Havla, J.
Journal of Neuroinflammation 16
(1): 154.
25 July 2019
Cognitive impairment in neuromyelitis optica spectrum disorders: a review of clinical and neuroradiological features.
Oertel, F.C., Schließeit, J., Brandt, A.U. and Paul, F.
Frontiers in Neurology 10
: 608.
12 June 2019
Novel uses of retinal imaging with optical coherence tomography in multiple sclerosis.
Oertel, F.C., Zimmermann, H.G., Brandt, A.U. and Paul, F.
Expert Review of Neurotherapeutics 19
(1): 31-43.
2 January 2019
Strategies for in vivo reprogramming.
Ofenbauer, A. and Tursun, B.
Current Opinion in Cell Biology 61
: 9-15.
December 2019
Chloroplast cold-resistance is mediated by the acidic domain of the RNA binding protein CP31A.
Okuzaki, A., Lehniger, M.K., Muino, J.M., Lenzen, B., Rühe, Thilo, Leister, D., Ohler, U. and Schmitz-Linneweber, C.
bioRxiv
: 832337.
5 December 2019
Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study.
Olesen, M.N., Soelberg, K., Debrabant, B., Nilsson, A.C., Lillevang, S.T., Grauslund, J., Brandslund, I., Madsen, J.S., Paul, F., Smith, T.J., Jarius, S. and Asgari, N.
Journal of Neuroinflammation 16
(1): 59.
11 March 2019
Genetic deletion of the alamandine receptor MrgD leads to dilated cardiomyopathy in mice.
Oliveira, A.C., Melo, M.B., Motta-Santos, D., Peluso, A.A., Souza-Neto, F., da Silva, R.F., Almeida, J.F.Q., Canta, G., Reis, A.M., Goncalves, G., Cerri, G.G., Coutinho, D., de Jesus, I.C.G., Guatimosim, S., Linhares, N.D., Alenina, N., Bader, M., Campagnole-Santos, M.J. and Santos, R.A.S.
American Journal of Physiology Heart and Circulatory Physiology 316
(1): H123-H133.
January 2019
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases.
Omar, F., Findlay, J.E., Carfray, G., Allcock, R.W., Jiang, Z., Moore, C., Muir, A.L., Lannoy, M., Fertig, B.A., Mai, D., Day, J.P., Bolger, G., Baillie, G.S., Schwiebert, E., Klussmann, E., Pyne, N.J., Ong, A.C.M., Bowers, K., Adam, J.M., Adams, D.R., Houslay, M.D. and Henderson, D.J.P.
Proceedings of the National Academy of Sciences of the United States of America 116
(27): 13320-13329.
2 July 2019
Calcium-independent exo-endocytosis coupling at small central synapses.
Orlando, M., Schmitz, D., Rosenmund, C. and Herman, M.A.
Cell Reports 29
(12): 3767-3774.
17 December 2019
Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
Ortiz, M.V., Ahmed, S., Burns, M., Henssen, A.G., Hollmann, T.J., MacArthur, I., Gunasekera, S., Gaewsky, L., Bradwin, G., Ryan, J., Letai, A., He, Y., Naranjo, A., Chi, Y.Y., LaQuaglia, M., Heaton, T., Cifani, P., Dome, J.S., Gadd, S., Perlman, E., Mullen, E., Steen, H. and Kentsis, A.
JCI Insight 4
(15): e127098.
8 August 2019
Low-density granulocytes are a novel immunopathological feature in both multiple sclerosis and neuromyelitis optica spectrum disorder.
Ostendorf, L., Mothes, R., van Koppen, S., Lindquist, R.L., Bellmann-Strobl, J., Asseyer, S., Ruprecht, K., Alexander, T., Niesner, R.A., Hauser, A.E., Paul, F. and Radbruch, H.
Frontiers in Immunology 10
: 2725.
29 November 2019
P
Preformed chromatin topology assists transcriptional robustness of Shh during limb development.
Paliou, C., Guckelberger, P., Schöpflin, R., Heinrich, V., Esposito, A., Chiariello, A.M., Bianco, S., Annunziatella, C., Helmuth, J., Haas, S., Jerković, I., Brieske, N., Wittler, L., Timmermann, B., Nicodemi, M., Vingron, M., Mundlos, S. and Andrey, G.
Proceedings of the National Academy of Sciences of the United States of America 116
(25): 12390-12399.
18 June 2019
Damage of the lateral geniculate nucleus in MS: assessing the missing node of the visual pathway.
Papadopoulou, A., Gaetano, L., Pfister, A., Altermatt, A., Tsagkas, C., Morency, F., Brandt, A.U., Hardmeier, M., Chakravarty, M.M., Descoteaux, M., Kappos, L., Sprenger, T. and Magon, S.
Neurology 92
(19): e2240-e2249.
7 May 2019
Attack-related damage of thalamic nuclei in neuromyelitis optica spectrum disorders.
Papadopoulou, A., Oertel, F.C., Gaetano, L., Kuchling, J., Zimmermann, H., Chien, C., Siebert, N., Asseyer, S., Bellmann-Strobl, J., Ruprecht, K., Chakravarty, M.M., Scheel, M., Magon, S., Wuerfel, J., Paul, F. and Brandt, A.U.
Journal of Neurology Neurosurgery and Psychiatry 90
(10): 1156-1164.
October 2019
Quantitative 7T MRI does not detect occult brain damage in neuromyelitis optica.
Pasquier, B., Borisow, N., Rasche, L., Bellmann-Strobl, J., Ruprecht, K., Niendorf, T., Derfuss, T.J., Wuerfel, J., Paul, F. and Sinnecker, T.
Neurology Neuroimmunology & Neuroinflammation 6
(3): e541.
May 2019
The use of magnetic resonance imaging in the diagnosis of paediatric transverse myelitis.
Paul, F.
Developmental Medicine and Child Neurology 61
(9): 1001.
September 2019
Flammer syndrome and autoimmune inflammatory conditions of the central nervous system: multifactorial interrelations.
Paul, F.
Advances in Predictive, Preventive and Personalised Medicine 11
: 145-163.
2019
Homozygosity for the c.428delG variant in KIAA0586 in a healthy individual: implications for molecular testing in patients with Joubert syndrome.
Pauli, S., Altmüller, J., Schröder, S., Ohlenbusch, A., Dreha-Kulaczewski, S., Bergmann, C., Nürnberg, P., Thiele, H., Li, Y., Wollnik, B. and Brockmann, K.
Journal of Medical Genetics 56
(4): 261-264.
April 2019
Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer.
Penter, L., Dietze, K., Ritter, J., Lammoglia Cobo, M.F., Garmshausen, J., Aigner, F., Bullinger, L., Hackstein, H., Wienzek-Lischka, S., Blankenstein, T., Hummel, M., Dornmair, K. and Hansmann, L.
OncoImmunology 8
(6): e1586409.
24 March 2019
Domainoid: domain-oriented orthology inference.
Persson, E., Kaduk, M., Forslund, S.K. and Sonnhammer, E.L.L.
BMC Bioinformatics 20
(1): 523.
28 October 2019
Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles.
Petrova, V.N., Sawatsky, B., Han, A.X., Laksono, B.M., Walz, L., Parker, E., Pieper, K., Anderson, C.A., de Vries, R.D., Lanzavecchia, A., Kellam, P., von Messling, V., de Swart, R.L. and Russell, C.A.
Science Immunology 4
(41): eaay6125.
1 November 2019
Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.
Pfuhl, C., Grittner, U., Gieß, R.M., Scheel, M., Behrens, J.R., Rasche, L., Pache, F.C., Wenzel, R., Brandt, A.U., Bellmann-Strobl, J., Paul, F., Ruprecht, K. and Oechtering, J.
Neurology 93
(15): e1439-e1451.
8 October 2019
LiP-Quant, an automated chemoproteomic approach to identify drug targets in complex proteomes.
Piazza, I., Beaton, N., Bruderer, R., Knobloch, T., Barbisan, C., Siepe, I., Rinner, O., de Souza, N., Picotti, P. and Reiter, L.
bioRxiv
: 860072.
1 December 2019
Transglutaminase 1 replacement therapy successfully mitigates the autosomal recessive congenital ichthyosis phenotype in full-thickness skin disease equivalents.
Plank, R., Yealland, G., Miceli, E., Lima Cunha, D., Graff, P., Thomforde, S., Gruber, R., Moosbrugger-Martinz, V., Eckl, K., Calderón, M., Hennies, H.C. and Hedtrich, S.
Journal of Investigative Dermatology 139
(5): 1191-1195.
May 2019
Small-molecule lysophosphatidic acid receptor 5 (LPAR5) antagonists: versatile pharmacological tools to regulate inflammatory signaling in BV-2 microglia cells.
Plastira, I., Joshi, L., Bernhart, E., Schoene, J., Specker, E., Nazare, M. and Sattler, W.
Frontiers in Cellular Neuroscience 13
: 531.
29 December 2019
Development of a backward-mode photoacoustic microscope using a Fabry-Pérot sensor.
Pohle, U., Baumann, E., Pulwer, S., Villringer, C., Zhang, E.Z., Gerhardt, H. and Laufer, J.
In: SPIE BiOS 2019, 2-7 Feb 2019, San Francisco, CA, USA.
6 March 2019
Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
Poncette, L., Chen, X., Lorenz, F.K.M. and Blankenstein, T.
Journal of Clinical Investigation 129
(1): 324-335.
2 January 2019
A fully phased accurate assembly of an individual human genome.
Porubsky, D., Ebert, P., Audano, P.A., Vollger, M.R., Harvey, W.T., Munson, K.M., Sorensen, M., Sulovari, A., Haukness, M., Ghareghani, M., Lansdorp, P.M., Paten, B., Devine, S.E., Sanders, A.D., Lee, C., Chaisson, M.J.P., Korbel, J.O., Eichler, E.E. and Marschall, T.
bioRxiv
: 855049.
26 November 2019
The cortical states of wakefulness.
Poulet, J.F.A. and Crochet, S.
Frontiers in Systems Neuroscience 12
: 64.
January 2019
Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration.
Preising, M.N., Görg, B., Friedburg, C., Qvartskhava, N., Budde, B.S., Bonus, M., Toliat, M.R., Pfleger, C., Altmüller, J., Herebian, D., Beyer, M., Zöllner, H.J., Wittsack, H.J., Schaper, J., Klee, D., Zechner, U., Nürnberg, P., Schipper, J., Schnitzler, A., Gohlke, H., Lorenz, B., Häussinger, D. and Bolz, H.J.
FASEB Journal 33
(10): 11507-11527.
October 2019
Pain-prescription differences - an analysis of 500,000 discharge summaries.
Preissner, S., Siramshetty, V.B., Dunkel, M., Steinborn, P., Luft, F.C. and Preissner, R.
Current Drug Abuse Reviews 11
(1): 58-66.
2019
Long-term effects of Na(+)/Ca(2+) exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
Primessnig, U., Bracic, T., Levijoki, J., Otsomaa, L., Pollesello, P., Falcke, M., Pieske, B. and Heinzel, F.R.
European Journal of Heart Failure 21
(12): 1543-1552.
December 2019
Toward (19)F magnetic resonance thermometry: spin-lattice and spin-spin-relaxation times and temperature dependence of fluorinated drugs at 9.4 T.
Prinz, C., Delgado, P.R., Eigentler, T.W., Starke, L., Niendorf, T. and Waiczies, S.
Magnetic Resonance Materials in Physics Biology and Medicine 32
(1): 51-61.
February 2019
Linkage evidence for a two-locus inheritance of LQT-associated seizures in a multigenerational LQT family with a novel KCNQ1 loss-of-function mutation.
Prüss, H., Gessner, G., Heinemann, S.H., Rüschendorf, F., Ruppert, A.K., Schulz, H., Sander, T. and Rimpau, W.
Frontiers in Neurology 10
: 648.
June 2019
Comparison of zebrafish and mice knockouts for Megalencephalic Leukoencephalopathy proteins indicates that GlialCAM/MLC1 forms a functional unit.
Pérez-Rius, C., Folgueira, M., Elorza-Vidal, X., Alia, A., Hoegg-Beiler, M.B., Eeza, M.N.H., Díaz, M.L., Nunes, V., Barrallo-Gimeno, A. and Estévez, R.
Orphanet Journal of Rare Diseases 14
(1): 268.
21 November 2019
Q
KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells.
Qi, X.T., Li, Y.L., Zhang, Y.Q., Xu, T., Lu, B., Fang, L., Gao, J.Q., Yu, L.S., Zhu, D.F., Yang, B., He, Q.J. and Ying, M.D.
Acta Pharmacologica Sinica 40
(4): 546-555.
April 2019
Functional identity of hypothalamic melanocortin neurons depends on Tbx3.
Quarta, C., Fisette, A., Xu, Y., Colldén, G., Legutko, B., Tseng, Y.T., Reim, A., Wierer, M., De Rosa, M.C., Klaus, V., Rausch, R., Thaker, V.V., Graf, E., Strom, T.M., Poher, A.L., Gruber, T., Le Thuc, O., Cebrian-Serrano, A., Kabra, D., Bellocchio, L., Woods, S.C., Pflugfelder, G.O., Nogueiras, R., Zeltser, L., Grunwald Kadow, I.C., Moon, A., García-Cáceres, C., Mann, M., Treier, M., Doege, C.A. and Tschöp, M.H.
Nature Metabolism 1
(2): 222-235.
February 2019
R
Deleting full length titin versus the titin M-band region leads to differential mechanosignaling and cardiac phenotypes.
Radke, M.H., Polack, C., Methawasin, M., Fink, C., Granzier, H.L. and Gotthardt, M.
Circulation 139
(15): 1813-1827.
9 April 2019
The advent and rise of monoclonal antibodies.
Rajewsky, K.
Nature 575
(7781): 47-49.
November 2019
Interaction of pregnancy-specific glycoprotein 1 with integrin Α5β1 is a modulator of extravillous trophoblast functions.
Rattila, S., Dunk, C.E.E., Im, M., Grichenko, O., Zhou, Y., Cohen, M., Yanez-Mo, M., Blois, S.M., Yamada, K.M., Erez, O., Gomez-Lopez, N., Lye, S.J., Hinz, B., Romero, R. and Dveksler, G.
Cells 8
(11): 1369.
31 October 2019
Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.
Rauschmeier, R., Gustafsson, C., Reinhardt, A., A-Gonzalez, N., Tortola, L., Cansever, D., Subramanian, S., Taneja, R., Rossner, M.J., Sieweke, M.H., Greter, M., Månsson, R., Busslinger, M. and Kreslavsky, T.
EMBO Journal 38
(19): e101233.
1 October 2019
Anoctamin-4 is a bona fide Ca(2+)-dependent non-selective cation channel.
Reichhart, N., Schöberl, S., Keckeis, S., Alfaar, A.S., Roubeix, C., Cordes, M., Crespo-Garcia, S., Haeckel, A., Kociok, N., Föckler, R., Fels, G., Mataruga, A., Rauh, R., Milenkovic, V.M., Zühlke, K., Klussmann, E., Schellenberger, E. and Strauß, O.
Scientific Reports 9
(1): 2257.
19 February 2019
Sugars make the difference - Glycosylation of cardiodepressant antibodies regulates their activity in dilated cardiomyopathy.
Reinke, Y., Könemann, S., Chamling, B., Gross, S., Weitmann, K., Hoffmann, W., Klingel, K., Nauck, M., Fielitz, J., Dörr, M. and Felix, S.B.
International Journal of Cardiology 292
: 156-159.
1 October 2019
Next-generation sequencing of 32 genes associated with hereditary aortopathies and related disorders of connective tissue in a cohort of 199 patients.
Renner, S., Schüler, H., Alawi, M., Kolbe, V., Rybczynski, M., Woitschach, R., Sheikhzadeh, S., Stark, V.C., Olfe, J., Roser, E., Seggewies, F.S., Mahlmann, A., Hempel, M., Hartmann, M.J., Hillebrand, M., Wieczorek, D., Volk, A.E., Kloth, K., Koch-Hogrebe, M., Abou Jamra, R.i, Mitter, D., Altmüller, J., Wey-Fabrizius, A., Petersen, C., Rau, I., Borck, G., Kubisch, C., Mir, T.S., von Kodolitsch, Y., Kutsche, K. and Rosenberger, G.
Genetics in Medicine 21
(8): 1832-1841.
August 2019
Porous medium 3D flow simulation of contrast media washout in cardiac MRI reflects myocardial injury.
Riazy, L., Schaeffter, T., Olbrich, M., Schueler, J., von Knobelsdorff-Brenkenhoff, F., Niendorf, T. and Schulz-Menger, J.
Magnetic Resonance in Medicine 82
(2): 775-785.
August 2019
Clonality of circulating tumor cells in breast cancer brain metastasis patients.
Riebensahm, C., Joosse, S.A., Mohme, M., Hanssen, A., Matschke, J., Goy, Y., Witzel, I., Lamszus, K., Kropidlowski, J., Petersen, C., Kolb-Kokocinski, A., Sauer, S., Borgmann, K., Glatzel, M., Müller, V., Westphal, M., Riethdorf, S., Pantel, K. and Wikman, H.
Breast Cancer Research and Treatment 21
(1): 101.
3 September 2019
Jumping retroviruses nudge TADs apart.
Robson, M.I. and Mundlos, S.
Nature Genetics 51
(9): 1304-1305.
September 2019
Regulatory landscaping: how enhancer-promoter communication is sculpted in 3D.
Robson, M.I., Ringel, A.R. and Mundlos, S.
Molecular Cell 74
(6): 1110-1122.
20 June 2019
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.
Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K.T., Fragoulis, At., Kühl, A.A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C.E., Brenner, W., Malinowski, M.B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O.J., Tacke, F., Morkel, M. and Cramer, T.
Oncogene 38
(28): 5670-5685.
11 July 2019
Disentangling genetic and environmental effects on the proteotypes of individuals.
Romanov, N., Kuhn, M., Aebersold, R., Ori, A., Beck, M. and Bork, P.
Cell 177
(5): 1308-1318.
16 May 2019
The central nervous system contains ILC1s that differ from NK cells in the response to inflammation.
Romero-Suárez, S., Del Rio Serrato, A., Bueno, R.J., Brunotte-Strecker, D., Stehle, C., Figueiredo, C.A., Hertwig, L., Dunay, I.R., Romagnani, C. and Infante-Duarte, C.
Frontiers in Immunology 10
: 2337.
10 October 2019
Association of dietary intake of milk and dairy products with blood concentrations of insulin-like growth factor 1 (IGF-1) in Bavarian adults.
Romo Ventura, E., Konigorski, S., Rohrmann, S., Schneider, H., Stalla, G.K., Pischon, T., Linseisen, J. and Nimptsch, K.
European Journal of Nutrition 59
(4): 1413-1420.
June 2019
Evaluation of colorectal cancer subtypes and cell lines using deep learning.
Ronen, J., Hayat, S. and Akalin, A.
Life Science Alliance 2
(6): 201900517.
December 2019
Tissue sodium content and arterial hypertension in obese adolescents.
Roth, S., Markó, L., Birukov, A., Hennemuth, A., Kühnen, P., Jones, A., Ghorbani, N., Linz, P., Müller, D.N., Wiegand, S., Berger, F., Kuehne, T. and Kelm, M.
Journal of Clinical Medicine 8
(12): 2036.
21 November 2019
Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.
Rudolph, F., Hüttemeister, J., da Silva Lopes, K., Jüttner, R., Yu, L., Bergmann, N., Friedrich, D., Preibisch, S., Wagner, E., Lehnart, S.E., Gregorio, C.C. and Gotthardt, M.
Proceedings of the National Academy of Sciences of the United States of America 116
(50): 25126-25136.
10 December 2019
Novel calcineurin A (PPP3CA) variant associated with epilepsy, constitutive enzyme activation and downregulation of protein expression.
Rydzanicz, M., Wachowska, M., Cook, E.C., Lisowski, P., Kuźniewska, B., Szymańska, K., Diecke, S., Prigione, A., Szczałuba, K., Szybińska, A., Koppolu, A., Murcia Pienkowski, V., Kosińska, J., Wiweger, M., Kostrzewa, G., Brzozowska, M., Domańska-Pakieła, D., Jurkiewicz, E., Stawiński, P., Gromadka, A., Zielenkiewicz, P., Demkow, U., Dziembowska, M., Kuźnicki, J., Creamer, T.P. and Płoski, R.
European Journal of Human Genetics 27
(1): 61-69.
January 2019
Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group.
Rücker, F.G., Agrawal, M., Corbacioglu, A., Weber, D., Kapp-Schwoerer, S., Gaidzik, V.I., Jahn, N., Schroeder, T., Wattad, M., Lübbert, M., Koller, E., Kindler, T., Götze, K., Ringhoffer, M., Westermann, J., Fiedler, W., Horst, H.A., Greil, R., Schroers, R., Mayer, K., Heinicke, T., Krauter, J., Schlenk, R.F., Thol, F., Heuser, M., Ganser, A., Bullinger, L., Paschka, P., Döhner, H. and Döhner, K.
Blood 134
(19): 1608-1618.
7 November 2019
S
Serotonin synthesis protects the mouse colonic crypt from DNA damage and colorectal tumorigenesis.
Sakita, J.Y., Bader, M., Santos, E.S., Garcia, S.B., Minto, S.B., Alenina, N., Brunaldi, M.O., Carvalho, M.C., Vidotto, T., Gasparotto, B., Martins, R.B., Silva, W.A., Brandão, M.L., Leite, C.A., Cunha, F.Q., Karsenty, G., Squire, J.A., Uyemura, S.A. and Kannen, V.
Journal of Pathology 249
(1): 102-113.
September 2019
Gene expression changes and community turnover differentially shape the global ocean metatranscriptome.
Salazar, G., Paoli, L., Alberti, A., Huerta-Cepas, J., Ruscheweyh, H.J., Cuenca, M., Field, C.M., Coelho, L.P., Cruaud, C., Engelen, S., Gregory, A.C., Labadie, K., Marec, C., Pelletier, E., Royo-Llonch, M., Roux, S., Sánchez, P., Uehara, H., Zayed, A.A., Zeller, G., Carmichael, M., Dimier, C., Ferland, J., Kandels, S., Picheral, M., Pisarev, S., Poulain, J., Acinas, S.G., Babin, M., Bork, P., Bowler, C., de Vargas, C., Guidi, L., Hingamp, P., Iudicone, D., Karp-Boss, L., Karsenti, E., Ogata, H., Pesant, S., Speich, S., Sullivan, M.B., Wincker, P. and Sunagawa, S.
Cell 179
(5): 1068-1083.
14 November 2019
Electrophysiological and molecular characterization of the parasubiculum.
Sammons, R.P., Parthier, D., Stumpf, A. and Schmitz, D.
Journal of Neuroscience 39
(45): 8860-8876.
6 November 2019
Fast alignment of limited angle tomograms by projected cross correlation.
Sanchez, R.M., Mester, R. and Kudryashev, M.
In: 2019 27th European Signal Processing Conference (EUSIPCO), 2-6 Sep 2019, A Coruna, Spain.
18 November 2019
Single cell tri-channel-processing reveals structural variation landscapes and complex rearrangement processes.
Sanders, A.D., Meiers, S., Ghareghani, M., Porubsky, D., Jeong, H., van Vliet, M.A.C.C., Rausch, T., Richter-Pechańska, P., Kunz, J.B., Jenni, S., Raeder, B., Kinanen, V., Zimmermann, J., Benes, V., Schrappe, M., Mardin, B.R., Kulozik, A., Bornhauser, B., Bourquin, J.P., Marschall, T. and Korbel, J.O.
bioRxiv
: 849604.
21 November 2019
Advantages and challenges of cardiovascular and lymphatic studies in zebrafish research.
Santoro, M.M., Beltrame, M., Panáková, D., Siekmann, A.F., Tiso, N., Venero Galanternik, M., Jung, H.M. and Weinstein, B.M.
Frontiers in Cell and Developmental Biology 7
: 89.
May 2019
Thimet oligopeptidase (EC 3.4.24.15) key functions suggested by knockout mice phenotype characterization.
Santos, N.B.D., Franco, R.D., Camarini, R., Munhoz, C.D., Eichler, R.A.S., Gewehr, M.C.F., Reckziegel, P., Llanos, R.P., Dale, C.S., da Silva, V.R.O., Borges, V.F., Lima, B.H.F., Cunha, F.Q., Visniauskas, B., Chagas, J.R., Tufik, S., Peres, F.F., Abilio, V.C., Florio, J.C., Iwai, L.K., Rioli, V., Presoto, B.C., Guimaraes, A.O., Pesquero, J.B., Bader, M., Castro, L.M. and Ferro, E.S.
Biomolecules 9
(8): 382.
19 August 2019
The renin-angiotensin system: going beyond the classical paradigms.
Santos, R.A.S., Oudit, G.Y., Verano-Braga, T., Canta, G., Steckelings, U.M. and Bader, M.
American Journal of Physiology Heart and Circulatory Physiology 316
(5): H958-H970.
May 2019
NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML.
Sasca, D., Szybinski, J., Schüler, A., Shah, V., Heidelberger, J., Haehnel, P.S., Dolnik, A., Kriege, O., Fehr, E.M., Gebhardt, W.H., Reid, G., Scholl, C., Theobald, M., Bullinger, L., Beli, P. and Kindler, T.
Blood 133
(21): 2305-2319.
23 May 2019
A federated in-memory database system for life sciences.
Schapranow, M.P., Perscheid, C., Wachsmann, A., Siegert, M., Bock, C., Horschig, F., Liedke, F., Brauer, J. and Plattner, H.
In: 9th, 10th, 11th International Workshop on Business Intelligence for the Real-Time Enterprise, BIRTE 2015, BIRTE 2016, BIRTE 2017; International Conference on Very Large Data Bases, VLDB 2017, 28 Aug - 1 Sep 2017, Munich, Germany.
2019
IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
Scheffold, A., Jebaraj, B.M.C., Tausch, E., Bloehdorn, J., Ghia, P., Yahiaoui, A., Dolnik, A., Blätte, T.J., Bullinger, L., Dheenadayalan, R.P., Li, L., Schneider, C., Chen, S.S., Chiorazzi, N., Dietrich, S., Seiffert, M., Tannheimer, S., Döhner, H., Mertens, D. and Stilgenbauer, S.
Blood 134
(6): 534-547.
8 August 2019
Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation.
Schewe, J., Seidel, E., Forslund, S., Marko, L., Peters, J., Muller, D.N., Fahlke, C., Stölting, G. and Scholl, U.
Nature Communications 10
(1): 5155.
14 November 2019
A pharmacological master key mechanism that unlocks the selectivity filter gate in K(+) channels.
Schewe, M., Sun, H., Mert, Ü., Mackenzie, A., Pike, A.C.W., Schulz, F., Constantin, C., Vowinkel, K.S., Conrad, L.J., Kiper, A.K., Gonzalez, W., Musinszki, M., Tegtmeier, M., Pryde, D.C., Belabed, H., Nazare, M., de Groot, B.L., Decher, N., Fakler, B., Carpenter, E.P., Tucker, S.J. and Baukrowitz, T.
Science 363
(6429): 875-880.
22 February 2019
Nitrosative stress drives heart failure with preserved ejection fraction.
Schiattarella, G.G., Altamirano, F., Tong, D., French, K.M., Villalobos, E., Kim, S.Y., Luo, X., Jiang, N., May, H.I., Wang, Z.V., Hill, T.M., Mammen, P.P.A., Huang, J., Lee, D.I., Hahn, V.S., Sharma, K., Kass, D.A., Lavandero, S., Gillette, T.G. and Hill, J.A.
Nature 568
(7752): 351-356.
18 April 2019
Inflammation in aortic stenosis: shaping the biomarkers network.
Schiattarella, G.G. and Perrino, C.
International Journal of Cardiology 274
: 279-280.
1 January 2019
Diagnostics and therapeutic implications of gut microbiota alterations in cardiometabolic diseases.
Schiattarella, G.G., Sannino, A., Esposito, G. and Perrino, C.
Trends in Cardiovascular Medicine 29
(3): 141-147.
April 2019
Microbial metabolites as predictive biomarkers: a paradigm shift for cardiovascular risk stratification.
Schiattarella, G.G. and Trimarco, B.
European Heart Journal 40
(32): 2710-2712.
21 August 2019
Deregulated splicing is a major mechanism of RNA-induced toxicity in Huntington's disease.
Schilling, J., Broemer, M., Atanassov, I., Duernberger, Y., Vorberg, I., Dieterich, C., Dagane, A., Dittmar, G., Wanker, E., van Roon-Mom, W., Winter, J. and Krauß, S.
Journal of Molecular Biology 431
(9): 1869-1877.
19 April 2019
Definition and quantification of six immune- and neuroregulatory serum proteins in healthy and demented elderly.
Schipke, C.G., Günter, O., Weinert, C., Scotton, P., Sigle, J.P., Kallarackal, J., Kabelitz, D., Finzen, A. and Feuerhelm-Heidl, A.
Neurodegenerative Disease Management 9
(4): 193-203.
August 2019
Extensive transmission of microbes along the gastrointestinal tract.
Schmidt, T.S.B., Hayward, M.R., Coelho, L.P., Li, S.S., Costea, P.I., Voigt, A.Y., Wirbel, J., Maistrenko, O.M., Alves, R.J.C., Bergsten, E., de Beaufort, C., Sobhani, I., Heintz-Buschart, A., Sunagawa, S., Zeller, G., Wilmes, P. and Bork, P.
eLife 8
: e42693.
12 February 2019
Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking.
Schmidtke, C., Tiede, S., Thelen, M., Käkelä, R., Jabs, S., Makrypidi, G., Sylvester, M., Schweizer, M., Braren, I., Brocke-Ahmadinejad, N., Cotman, S.L., Schulz, A., Gieselmann, V. and Braulke, T.
Journal of Biological Chemistry 294
(24): 9592-9604.
14 June 2019
TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells.
Schoeler, K., Aufschnaiter, A., Messner, S., Derudder, E., Herzog, S., Villunger, A., Rajewsky, K. and Labi, V.
FEBS Journal 286
(18): 3566-3581.
September 2019
Probing 2H-indazoles as template for SGK1, Tie2 and SRC kinase inhibitors.
Schoene, J., Gazzi, T., Lindemann, P., Christmann, M., Volkamer, A. and Nazaré, M.
ChemMedChem 14
(16): 1514-1527.
20 August 2019
Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures.
Schroeder, M.P., Bastian, L., Eckert, C., Gökbuget, N., James, A.R., Ortiz Tanchez, J., Schlee, C., Isaakidis, K., Häupl, B., Baum, K., Migueles Lozano, O.A., Kouidri, K., Pan, K.T., Urlaub, H., Schwartz, S., Burmeister, T., von Stackelberg, A., Hoelzer, D., Pfeiffer, H., Rieger, M.A., Göllner, S., Oellerich, T., Horstman, M., Schrappe, M., Wolf, J., Kirschner-Schwabe, R., Brüggemann, M., Müller-Tidow, C., Serve, H., Neumann, M. and Baldus, C.D.
Scientific Reports 9
(1): 4188.
12 March 2019
Severe heart failure and the need for mechanical circulatory support and heart transplantation in pediatric patients with myocarditis: results from the prospective multicenter registry "MYKKE".
Schubert, S., Opgen‐Rhein, B., Boehne, M., Weigelt, A., Wagner, R., Müller, G., Rentzsch, A., zu Knyphausen, E., Fischer, M., Papakostas, K., Wiegand, G., Ruf, B., Hannes, T., Reineker, K., Kiski, D., Khalil, M., Steinmetz, M., Fischer, G., Pickardt, T., Klingel, K., Messroghli, D.R. and Degener, F.
Pediatric Transplantation 23
(7): e13548.
November 2019
Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage.
Schulz, A., Müller, N.V., van de Lest, N.A., Eisenreich, A., Schmidbauer, M., Barysenka, A., Purfürst, B., Sporbert, A., Lorenzen, T., Meyer, A.M., Herlan, L., Witten, A., Rühle, F., Zhou, W., de Heer, E., Scharpfenecker, M., Panáková, D., Stoll, M. and Kreutz, R.
eLife 8
: e42068.
22 March 2019
SigsPack, a package for cancer mutational signatures.
Schumann, F., Blanc, E., Messerschmidt, C., Blankenstein, T., Busse, A. and Beule, D.
BMC Bioinformatics 20
(1): 450.
2 September 2019
A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test.
Scioscia, M., Dekker, G.A., Chaouat, G., Dawonauth, L., Dechend, R., Goldman-Wohl, D., Gumilar, E., Karumanchi, S.A., Kell, D.B., Rademacher, T.W., Robertson, S., Saito, S., Scherjon, S., Staff, A.C., Vatish, M. and Robillard, P.Y.
Lancet Global Health 7
(10): e1312-e1313.
October 2019
Terrestrial mammal surveillance using hybridization capture of environmental DNA from African waterholes.
Seeber, P.A., McEwen, G.K., Löber, U., Förster, D.W., East, M.L., Melzheimer, J. and Greenwood, A.D.
Molecular Ecology Resources 19
(6): 1486-1496.
November 2019
Quantitative single-residue bioorthogonal labeling of G protein-coupled receptors in live cells.
Serfling, R., Seidel, L., Bock, A., Lohse, M.J., Annibale, P. and Coin, I.
ACS Chemical Biology 14
(6): 1141-1149.
21 June 2019
A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.
Sharir, A., Marangoni, P., Zilionis, R., Wan, M., Wald, T., Hu, J.K., Kawaguchi, K., Castillo-Azofeifa, D., Epstein, L., Harrington, K., Pagella, P., Mitsiadis, T., Siebel, C.W., Klein, A.M. and Klein, O.D.
Nature Cell Biology 21
(9): 1102-1112.
September 2019
Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b.
Sharp, T.H., Boyle, A.L., Diebolder, C.A., Kros, A., Koster, A. and Gros, P.
Proceedings of the National Academy of Sciences of the United States of America 116
(24): 11900-11905.
11 June 2019
PCNA-mediated degradation of p21 coordinates the DNA damage response and cell cycle regulation in individual cells.
Sheng, C., Mendler, I.H., Rieke, S., Snyder, P., Jentsch, M., Friedrich, D., Drossel, B. and Loewer, A.
Cell Reports 27
(1): 48-58.
2 April 2019
Differential cell susceptibilities to kras(G12D) in the setting of obstructive chronic pancreatitis.
Shi, C., Pan, F.C., Kim, J.N., Washington, M.K., Padmanabhan, C., Meyer, C.T., Kopp, J.L., Sander, M., Gannon, M., Beauchamp, R.D., Wright, C.V. and Means, A.L.
Cellular and molecular gastroenterology and hepatology 8
(4): 579-594.
31 October 2019
Disease overarching mechanisms that explain and predict outcome of patients with high cardiovascular risk: rationale and design of the Berlin Long-term Observation of vascular events (BeLOVE) study.
Siegerink, B., Weber, J., Ahmadi, M., Eckardt, K.U., Edelmann, F., Endres, M., Gerhardt, H., Haubold, K., Hübner, N., Landmesser, U., Leistner, D., Mai, K., Müller, D.N., Pieske, B., Rauch, G., Schmidt, S., Schmidt-Ott, K., Schulz-Menger, J., Spranger, J. and Pischon, T.
medRxiv
: 19001024.
15 July 2019
Cien años de microglía: milestones in a century of microglial research.
Sierra, A., Paolicelli, R.C. and Kettenmann, H.
Trends in Neurosciences 42
(11): 778-792.
November 2019
Molecular mechanisms of kidney injury and repair in arterial hypertension.
Sievers, L.K. and Eckardt, K.U.
International Journal of Molecular Sciences 20
(9): 2138.
30 April 2019
R-spondin-3 induces secretory, antimicrobial Lgr5(+) cells in the stomach.
Sigal, M., Del Mar Reinés, M., Müllerke, S., Fischer, C., Kapalczynska, M., Berger, H., Bakker, E.R.M., Mollenkopf, H.J., Rothenberg, M.E., Wiedenmann, B., Sauer, S. and Meyer, T.F.
Nature Cell Biology 21
(7): 812-823.
July 2019
Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery.
Simonetti, G., Padella, A., do Valle, I.F., Fontana, M.C., Fonzi, E., Bruno, S., Baldazzi, C., Guadagnuolo, V., Manfrini, M., Ferrari, A., Paolini, S., Papayannidis, C., Marconi, G., Franchini, E., Zuffa, E., Laginestra, M.A., Zanotti, F., Astolfi, A., Iacobucci, I., Bernardi, S., Sazzini, M., Ficarra, E., Hernandez, J.M., Vandenberghe, P., Cools, J., Bullinger, L., Ottaviani, E., Testoni, N., Cavo, M., Haferlach, T., Castellani, G., Remondini, D. and Martinelli, G.
Cancer 125
(5): 712-725.
1 March 2019
A 3D model of a human epiblast reveals BMP4-driven symmetry breaking.
Simunovic, M., Metzger, J.J., Etoc, F., Yoney, A., Ruzo, A., Martyn, I., Croft, G., You, D.S., Brivanlou, A.H. and Siggia, E.D.
Nature Cell Biology 21
(7): 900-910.
July 2019
Deconstructing age reprogramming.
Singh, P.B., Laktionov, P.P. and Newman, A.G.
Journal of Biosciences 44
(4): 106.
September 2019
Evaluation of the central vein sign as a diagnostic imaging biomarker in multiple sclerosis.
Sinnecker, T., Clarke, M.A., Meier, D., Enzinger, C., Calabrese, M., De Stefano, N., Pitiot, A., Giorgio, A., Schoonheim, M.M., Paul, F., Pawlak, M.A., Schmidt, R., Kappos, L., Montalban, X., Rovira, À., Evangelou, N. and Wuerfel, J.
JAMA Neurology 76
(12): 1446-1456.
December 2019
Neurodevelopmental disorder associated with IRF2BPL gene mutation: expanding the phenotype?
Skorvanek, M., Dusek, P., Rydzanicz, M., Walczak, A., Kosinska, J., Kostrzewa, G., Rydzanicz, M., Han, V., Dosekova, P., Gdovinova, Z., Lehotska, Z., Lisowski, P. and Ploski, R.
Parkinsonism & Related Disorders 62
: 239-241.
24 January 2019
R-loops enhance polycomb repression at a subset of developmental regulator genes.
Skourti-Stathaki, K., Torlai Triglia, E., Warburton, M., Voigt, P., Bird, A. and Pombo, A.
Molecular Cell 73
(5): 930-945.
7 March 2019
Cardiac 123I-MIBG scintigraphy in neurodegenerative Parkinson syndromes: performance and pitfalls in clinical practice.
Skowronek, C., Zange, L. and Lipp, A.
Frontiers in Neurology 10
: 152.
February 2019
Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance.
Slater, R.E., Strom, J.G., Methawasin, Mei, Liss, M., Gotthardt, M., Sweitzer, N. and Granzier, H.L.
Journal of General Physiology 151
(1): 42-52.
January 2019
A SEPT1-based scaffold is required for Golgi integrity and function.
Song, K., Gras, C., Capin, G., Gimber, N., Lehmann, M., Mohd, S., Puchkov, D., Rödiger, M., Wilhelmi, I., Daumke, O., Schmoranzer, J., Schürmann, A. and Krauss, M.
Journal of Cell Science 132
(3): jcs225557.
1 February 2019
Chronic CD30-signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.
Sperling, S.A., Fiedler, P., Lechner, M., Pollithy, A., Ehrenberg, S., Schiefer, A.I., Kenner, L., Feuchtinger, A., Kühn, R., Swinerd, G., Schmidt-Supprian, M., Strobl, L.J. and Zimber-Strobl, U.
Blood 133
(24): 2597-2609.
13 June 2019
Associations of current, childhood, and adolescent milk intake with serum insulin-like growth factor (IGF)-1 and IGF binding protein 3 concentrations in adulthood.
Srinivasan, V., Nimptsch, K. and Rohrmann, S.
Nutrition and Cancer 71
(6): 931-938.
2019
Imaging glioma progression by intravital microscopy.
Stanchi, F., Matsumoto, K. and Gerhardt, H.
Methods in Molecular Biology 1862
: 227-243.
2019
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Starossom, S.C., Campo Garcia, J., Woelfle, T., Romero-Suarez, S., Olah, M., Watanabe, F., Cao, L., Yeste, A., Tukker, J.J., Quintana, F.J., Imitola, J., Witzel, F., Schmitz, D., Morkel, M., Paul, F., Infante-Duarte, C. and Khoury, S.J.
Nature Communications 10
(1): 217.
15 January 2019
Does time equal vision in the acute treatment of a cohort of AQP4 and MOG optic neuritis?
Stiebel-Kalish, H., Hellmann, M.A., Mimouni, M., Paul, F., Bialer, O., Bach, M. and Lotan, I.
Neurology Neuroimmunology & Neuroinflammation 6
(4): e572.
July 2019
Scalable workflows and reproducible data analysis for genomics.
Strozzi, F., Janssen, R., Wurmus, R., Crusoe, M.R., Githinji, G., Di Tommaso, P., Belhachemi, D., Möller, S., Smant, G., de Ligt, J. and Prins, P.
Methods in Molecular Biology 1910
: 723-745.
2019
Cardiac magnetic resonance imaging at 7 Tesla.
Stäb, D., Al Najjar, A., O'Brien, K., Strugnell, W., Richer, J., Rieger, J., Niendorf, T. and Barth, M.
Journal of Visualized Experiments
(143): e55853.
6 January 2019
Human-specific tandem repeat expansion and differential gene expression during primate evolution.
Sulovari, A., Li, R., Audano, P.A., Porubsky, D., Vollger, M.R., Logsdon, G.A., Warren, W.C., Pollen, A.A., Chaisson, M.J.P. and Eichler, E.E.
Proceedings of the National Academy of Sciences of the United States of America 116
(46): 23243-23253.
12 November 2019
A semisynthetic peptide-metalloporphyrin responsive matrix for artificial photosynthesis.
Sun, Z., Diebolder, C.A., Renault, L. and de Groot, H.
ChemPhotoChem 3
(8): 630-635.
August 2019
53BP1 supports immunoglobulin class switch recombination independently of its DNA double-strand break end protection function.
Sundaravinayagam, D., Rahjouei, A., Andreani, M., Tupiņa, D., Balasubramanian, S., Saha, T., Delgado-Benito, V., Coralluzzo, V., Daumke, O. and Di Virgilio, M.
Cell Reports 28
(6): 1389-1399.
6 August 2019
A convex relaxation for multi-graph matching.
Swoboda, P., Kainmüller, D., Mokarian, A., Theobalt, C. and Bernard, F.
In: 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 16-20 Jun 2019, Long Beach, CA, USA.
2019
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets.
Szklarczyk, D., Gable, A.L., Lyon, D., Junge, A., Wyder, S., Huerta-Cepas, J., Simonovic, M., Doncheva, N.T., Morris, J.H., Bork, P., Jensen, L.J. and von Mering, C.
Nucleic Acids Research 47
(D1): D607-D613.
8 January 2019
Fast cross correlation for limited angle tomographic data.
Sánchez, R.M., Mester, R. and Kudryashev, M.
Lecture Notes in Computer Science 11482
: 415-426.
2019
T
Postprandial duration influences the association of insulin-related dietary indexes and plasma C-peptide concentrations in adult men and women.
Tabung, F.K., Nimptsch, K. and Giovannucci, E.L.
Journal of Nutrition 149
(2): 286-294.
1 February 2019
Urinary renin in patients and mice with diabetic kidney disease.
Tang, J., Wysocki, J., Ye, M., Vallés, P.G., Rein, J., Shirazi, M., Bader, M., Gomez, R.A., Sequeira-Lopez, M.L.S., Afkarian, M. and Batlle, D.
Hypertension 74
(1): 83-94.
July 2019
Venetoclax resistance and acquired mutations in chronic lymphocytic leukemia.
Tausch, E., Close, W., Dolnik, A., Bloehdorn, J., Chyla, B., Bullinger, L., Döhner, H., Mertens, D. and Stilgenbauer, S.
Haematologica 104
(9): e434-e437.
September 2019
The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution.
Taylor, D.M., Aronow, B.J., Tan, K., Bernt, K., Salomonis, N., Greene, C.S., Frolova, A., Henrickson, S.E., Wells, A., Pei, L., Jaiswal, J.K., Whitsett, J., Hamilton, K.E., MacParland, S.A., Kelsen, J., Heuckeroth, R.O., Potter, S.S., Vella, L.A., Terry, N.A., Ghanem, L.R., Kennedy, B.C., Helbig, I., Sullivan, K.E., Castelo-Soccio, L., Kreigstein, A., Herse, F., Nawijn, M.C., Koppelman, G.H., Haendel, M., Harris, N.L., Rokita, J.L., Zhang, Y., Regev, A., Rozenblatt-Rosen, O., Rood, J.E., Tickle, T.L, Vento-Tormo, R., Alimohamed, S., Lek, M., Mar, J.C., Loomes, K.M., Barrett, D.M., Uapinyoying, P., Beggs, A.H., Agrawal, P.B., Chen, Y.W., Muir, A.B., Garmire, L.X., Snapper, S.B., Nazarian, J., Seeholzer, S.H., Fazelinia, H., Singh, L.N., Faryabi, R.B., Raman, P., Dawany, N., Xie, H.M., Devkota, B., Diskin, S.J., Anderson, S.A., Rappaport, E.F., Peranteau, W., Wikenheiser-Brokamp, K.A., Teichmann, S., Wallace, D., Peng, T., Ding, Y.Y., Kim, M.S., Xing, Y., Kong, S.W., Bönnemann, C.G., Mandl, K.D. and White, P.S.
Developmental Cell 49
(1): 10-29.
8 April 2019
A transcriptome-wide analysis deciphers distinct roles of G1 cyclins in temporal organization of the yeast cell cycle.
Teufel, L., Tummler, K., Flöttmann, M., Herrmann, A., Barkai, N. and Klipp, E.
Scientific Reports 9
(1): 3343.
4 March 2019
Identification of proteins and miRNAs that specifically bind an mRNA in vivo.
Theil, K., Imami, K. and Rajewsky, N.
Nature Communications 10
(1): 4205.
16 September 2019
The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: a phosphatidylserine flippase.
Theorin, L., Faxén, K., Sørensen, D.M., Migotti, R., Dittmar, G., Schiller, J., Daleke, D.L., Palmgren, M., López-Marqués, R.L. and Pomorski, T.G.
Biochemical Journal 476
(5): 783-794.
6 March 2019
Critical parameters for the controlled synthesis of nanogels suitable for temperature-triggered protein delivery.
Theune, L.E., Charbaji, R., Kar, M., Wedepohl, S., Hedtrich, S. and Calderón, M.
Materials Science and Engineering C: Materials for Biological Applications 100
: 141-151.
July 2019
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation.
Thomas, A.M., Manghi, P., Asnicar, F., Pasolli, E., Armanini, F., Zolfo, M., Beghini, F., Manara, S., Karcher, N., Pozzi, C., Gandini, S., Serrano, D., Tarallo, S., Francavilla, A., Gallo, G., Trompetto, M., Ferrero, G., Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Wirbel, J., Schrotz-King, P., Ulrich, C.M., Brenner, H., Arumugam, M., Bork, P., Zeller, G., Cordero, F., Dias-Neto, E., Setubal, J.C., Tett, A., Pardini, B., Rescigno, M., Waldron, L., Naccarati, A. and Segata, N.
Nature Medicine 25
(4): 667-678.
April 2019
Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney.
Thomson, M.N., Schneider, W., Mutig, K., Ellison, D.H., Kettritz, R. and Bachmann, S.
American Journal of Physiology Renal Physiology 316
(2): F292-F300.
February 2019
Population-level analysis of Blastocystis subtype prevalence and variation in the human gut microbiota.
Tito, R.Y., Chaffron, S., Caenepeel, C., Lima-Mendez, G., Wang, J., Vieira-Silva, S., Falony, G., Hildebrand, F., Darzi, Y., Rymenans, L., Verspecht, C., Bork, P., Vermeire, S., Joossens, M. and Raes, J.
Gut 68
(7): 1180-1189.
7 June 2019
SarcTrack: an adaptable software tool for efficient large-scale analysis of sarcomere function in hiPSC-cardiomyocytes.
Toepfer, C.N., Sharma, A., Cicconet, M., Garfinkel, A.C., Mücke, M., Neyazi, M., Willcox, J.A.L., Agarwal, R., Schmid, M., Rao, J., Ewoldt, J., Pourquié, O., Chopra, A., Chen, C.S., Seidman, J.G. and Seidman, C.E.
Circulation Research 124
(8): 1172-1183.
12 April 2019
Female sex is protective in a preclinical model of heart failure with preserved ejection fraction.
Tong, D., Schiattarella, G.G., Jiang, N., May, H.I., Lavandero, S., Gillette, T.G. and Hill, J.A.
Circulation 140
(21): 1769-1771.
19 November 2019
Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors.
Tran, N.T., Bashir, S., Li, X., Rossius, J., Chu, V.T., Rajewsky, K. and Kühn, R.
Frontiers in Genetics 10
: 365.
30 April 2019
Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells.
Tran, N.T., Sommermann, T., Graf, R., Trombke, J., Pempe, J., Petsch, K., Kühn, R., Rajewsky, K. and Chu, V.T.
Cell Reports 28
(13): 3510-3522.
24 September 2019
Anti-β1-adrenoreceptor auto-antibodies in elderly heart failure patients.
Trippel, T.D., Mueller, D.N., Obradovic, D., Edelmann, F., Tahirovic, E., Wilck, N., Riemekasten, G., Dragun, D., Busjahn, A., Heidecke, H., Junker, J., Pieske, B., Dungen, H.D. and Dechend, R.
Frontiers in Bioscience 24
: 1037-1049.
1 March 2019
Distinguishing between biological and technical replicates in hypertension research on isolated arteries.
Tsvetkov, D., Kolpakov, E., Kassmann, M., Schubert, R. and Gollasch, M.
Frontiers in Medicine 6
: 126.
June 2019
How RB1CC1/FIP200 claws its way to autophagic engulfment of SQSTM1/p62-ubiquitin condensates.
Turco, E., Witt, M., Abert, C., Bock-Bierbaum, T., Su, M.Y., Trapannone, R., Sztacho, M., Danieli, A., Shi, X., Zaffagnini, G., Gamper, A., Schuschnig, M., Fracchiolla, D., Bernklau, D., Romanov, J., Hartl, M., Hurley, J.H., Daumke, O. and Martens, S.
Autophagy 15
(8): 1475-1477.
August 2019
FIP200 claw domain binding to p62 promotes autophagosome formation at ubiquitin condensates.
Turco, E., Witt, M., Abert, C., Bock-Bierbaum, T., Su, M.Y., Trapannone, R., Sztacho, M., Danieli, A., Shi, X., Zaffagnini, G., Gamper, A., Schuschnig, M., Fracchiolla, D., Bernklau, D., Romanov, J., Hartl, M., Hurley, J.H., Daumke, O. and Martens, S.
Molecular Cell 74
(2): 330-346.
18 April 2019
Remodeling of substrate consumption in the murine sTAC model of heart failure.
Turer, A., Altamirano, F., Schiattarella, G., May, H., Gillette, T.G., Malloy, C.R. and Merritt, M.E.
Journal of Molecular and Cellular Cardiology 134
: 144-153.
September 2019
U
Interrogation of human hematopoiesis at single-cell and single-variant resolution.
Ulirsch, J.C., Lareau, C.A., Bao, E.L., Ludwig, L.S., Guo, M.H., Benner, C., Satpathy, A.T., Kartha, V.K., Salem, R.M., Hirschhorn, J.N., Finucane, H.K., Aryee, M.J., Buenrostro, J.D. and Sankaran, V.G.
Nature Genetics 51
(4): 683-693.
April 2019
Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels.
Ullrich, F., Blin, S., Lazarow, K., Daubitz, T., von Kries, J.P. and Jentsch, T.J.
eLife 8
: e49187.
18 July 2019
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta, E.C., Vieira-Vieira, C.H., Hick, T., Wessels, H.H., Figini, D., Moschall, R., Medenbach, J., Ohler, U., Granneman, S., Selbach, M. and Beckmann, B.M.
Nature Communications 10
(1): 990.
1 March 2019
Conserved pseudoknots in lncRNA MEG3 are essential for stimulation of the p53 pathway.
Uroda, T., Anastasakou, E., Rossi, A., Teulon, J.M., Pellequer, J.L., Annibale, P., Pessey, O., Inga, A., Chillón, I. and Marcia, M.
Molecular Cell 75
(5): 982-995.
5 September 2019
V
Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain.
Van Steenwinckel, J., Schang, A.L., Krishnan, M.L., Degos, V., Delahaye-Duriez, A., Bokobza, C., Csaba, Z., Verdonk, F., Montané, A., Sigaut, S., Hennebert, O., Lebon, S., Schwendimann, L., Le Charpentier, T., Hassan-Abdi, R., Ball, G., Aljabar, P., Saxena, A., Holloway, R.K., Birchmeier, W., Baud, O., Rowitch, D., Miron, V., Chretien, F., Leconte, C., Besson, V.C., Petretto, E.G., Edwards, A.D., Hagberg, H., Soussi-Yanicostas, N., Fleiss, B. and Gressens, P.
Brain 142
(12): 3806-3833.
December 2019
Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities.
Vasaikar, S., Huang, C., Wang, X., Petyuk, V.A., Savage, S.R., Wen, B., Dou, Y., Zhang, Y., Shi, Z., Arshad, O.A., Gritsenko, M.A., Zimmerman, L.J., McDermott, J.E., Clauss, T.R., Moore, R.J., Zhao, R., Monroe, M.E., Wang, Y.T., Chambers, M.C., Slebos, R.J.C., Lau, K.S., Mo, Q., Ding, L., Ellis, M., Thiagarajan, M., Kinsinger, C.R., Rodriguez, H., Smith, R.D., Rodland, K.D., Liebler, D.C., Liu, T. and Zhang, B.
Cell 177
(4): 1035-1049.
2 May 2019
Multiple sclerosis.
Veauthier, C. and Paul, F.
In:
Handbook of Sleep Disorders in Medical Conditions.
Elsevier / Academic Press, 345-369.
ISBN 978-0-12-813014-8
2019
Contactless recording of sleep apnea and periodic leg movements by nocturnal 3-D-video and subsequent visual perceptive computing.
Veauthier, C., Ryczewski, J., Mansow-Model, S., Otte, K., Kayser, B., Glos, M., Schöbel, C., Paul, F., Brandt, A.U. and Penzel, T.
Scientific Reports 9
(1): 16812.
14 November 2019
Association of a PD-L2 gene polymorphism with chronic lymphatic filariasis in a South Indian cohort.
Venugopal, G., O'Regan, N.L., Babu, S., Schumann, R.R., Srikantam, A., Merle, R., Hartmann, S. and Steinfelder, S.
American Journal of Tropical Medicine and Hygiene 100
(2): 344-350.
February 2019
Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal, R., Wagner, J.U.G., Braeuning, C., Fischer, C., Patrick, R., Tombor, L., Muhly-Reinholz, M., John, D., Kliem, M., Conrad, T., Guimarães-Camboa, N., Harvey, R., Dimmeler, S. and Sauer, S.
JCI Insight 4
(22): e131092.
14 November 2019
Canonical BMP signaling in tubular cells mediates recovery after acute kidney injury.
Vigolo, E., Markó, L., Hinze, C., Müller, D.N., Schmidt-Ullrich, R. and Schmidt-Ott, K.M.
Kidney International 95
(1): 108-122.
January 2019
Fibroblast primary cilia are required for cardiac fibrosis.
Villalobos, E., Criollo, A., Schiattarella, G.G., Altamirano, F., French, K.M., May, H.I., Jiang, N., Nguyen, N.U.N., Romero, D., Roa, J.C., García, L., Diaz-Araya, G., Morselli, E., Ferdous, A., Conway, S.J., Sadek, H.A., Gillette, T.G., Lavandero, S. and Hill, J.A.
Circulation 139
(20): 2342-2357.
14 May 2019
Applying synergy metrics to oncology combination screening data: agreements, disagreements and pitfalls.
Vlot, A.H.C., Aniceto, N., Menden, M.P., Ulrich-Merzenich, G. and Bender, A.
Drug Discovery Today 24
(12): 2286-2298.
December 2019
Human sFLT1 leads to severe changes in placental differentiation and vascularization in a transgenic hsFLT1/rtTA FGR mouse model.
Vogtmann, R., Kühnel, E., Dicke, N., Verkaik-Schakel, R.N., Plösch, T., Schorle, H., Stojanovska, V., Herse, F., Köninger, A., Kimmig, R., Winterhager, E. and Gellhaus, A.
Frontiers in Endocrinology 10
: 165.
March 2019
Fluconazole increases osmotic water transport in renal collecting duct through effects on aquaporin-2 trafficking.
Vukićević, T., Hinze, C., Baltzer, S., Himmerkus, N., Quintanova, C., Zühlke, K., Compton, F., Ahlborn, R., Dema, A., Eichhorst, J., Wiesner, B., Bleich, M., Schmidt-Ott, K.M. and Klussmann, E.
Journal of the American Society of Nephrology 30
(5): 795-810.
May 2019
The translational landscape of the human heart.
van Heesch, S., Witte, F., Schneider-Lunitz, V., Schulz, J.F., Adami, E., Faber, A., Kirchner, M., Maatz, H., Blachut, S., Sandmann, C.L., Kanda, M., Worth, C.L., Schafer, S., Calviello, L., Merriott, R., Patone, G., Hummel, O., Wyler, E., Obermayer, B., Mücke, M., Lindberg, E.L., Trnka, F., Memczak, S., Schilling, M., Felkin, L.E., Barton, P.J.R., Quaife, N.M., Vanezis, K., Diecke, S., Mukai, M., Mah, N., Oh, S.J., Kurtz, A., Schramm, C., Schwinge, D., Sebode, M., Harakalova, M., Asselbergs, F.W., Vink, A., de Weger, R.A., Viswanathan, S., Widjaja, A.A., Gärtner-Rommel, A., Milting, H., Dos Remedios, C., Knosalla, C., Mertins, P., Landthaler, M., Vingron, M., Linke, W.A., Seidman, J.G., Seidman, C.E., Rajewsky, N., Ohler, U., Cook, S.A. and Hubner, N.
Cell 178
(1): 242-260.
27 June 2019
Lack of brain serotonin affects feeding and differentiation of newborn cells in the adult hypothalamus.
van Lingen, M., Sidorova, M., Alenina, N. and Klempin, F.
Frontiers in Cell and Developmental Biology 7
: 65.
April 2019
Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma.
von Hoff, L., Kärgel, E., Franke, V., McShane, E., Schulz-Beiss, K.W., Patone, G., Schleussner, N., Kolesnichenko, M., Hübner, N., Daumke, O., Selbach, M., Akalin, A., Mathas, S. and Scheidereit, C.
Blood 133
(13): 1489-1494.
28 March 2019
Empfehlungen zu kardialen MRT-Untersuchungen bei Patienten mit Herzschrittmachern und implantierbaren Kardioverter-Defibrillatoren [Recommendations for cardiac magnetic resonance imaging in patients with cardiac pacemakers andimplantable cardioverter defibrillators].
von Knobelsdorff-Brenkenhoff, F., Bauer, W.R., Deneke, T., Fleck, E., Rolf, A., Schulz-Menger, J., Sommer, P., Tillmanns, C. and Eitel, I.
Kardiologe 13
(2): 75-86.
April 2019
W
The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
Wagener, R., Seufert, J., Raimondi, F., Bens, S., Kleinheinz, K., Nagel, I., Altmüller, J., Thiele, H., Hübschmann, D., Kohler, C.W., Nürnberg, P., Au-Yeung, R., Burkhardt, B., Horn, H., Leoncini, L., Jaffe, E.S., Ott, G., Rymkiewicz, G., Schlesner, M., Russell, R.B., Klapper, W. and Siebert, R.
Blood 133
(9): 962-966.
28 February 2019
Efficacy of high-frequency repetitive transcranial magnetic stimulation in schizophrenia patients with treatment-resistant negative symptoms treated with clozapine.
Wagner, E., Wobrock, T., Kunze, B., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Cordes, J., Wölwer, W., Winterer, G., Gaebel, W., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Siskind, D., Malchow, B., Strube, W., Schneider-Axmann, T., Falkai, P. and Hasan, A.
Schizophrenia Research 208
: 370-376.
June 2019
Fluorine-19 MRI at 21.1 T: enhanced spin-lattice relaxation of perfluoro-15-crown-5-ether and sensitivity as demonstrated in ex vivo murine neuroinflammation.
Waiczies, S., Rosenberg, J.T., Kuehne, A., Starke, L., Delgado, P.R., Millward, J., Prinz, C., dos Santos Periquito, J., Pohlmann, A., Waiczies, H. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 32
(1): 37-49.
February 2019
Special issue on fluorine-19 magnetic resonance: technical solutions, research promises and frontier applications.
Waiczies, S., Srinivas, M., Flögel, U., Boehm-Sturm, P. and Niendorf, T.
Magnetic Resonance Materials in Physics Biology and Medicine 32
(1): 1-3.
February 2019
Serotonin deficiency increases context-dependent fear learning through modulation of hippocampal activity.
Waider, J., Popp, S., Mlinar, B., Montalbano, A., Bonfiglio, F., Aboagye, B., Thuy, E., Kern, R., Thiel, C., Araragi, N., Svirin, E., Schmitt-Böhrer, A.G., Corradetti, R., Lowry, C.A. and Lesch, K.P.
Frontiers in Neuroscience 13
: 245.
April 2019
De novo mutations in FOXJ1 result in a motile ciliopathy with hydrocephalus and randomization of left/right body asymmetry.
Wallmeier, J., Frank, D., Shoemark, A., Nöthe-Menchen, T., Cindric, S., Olbrich, H., Loges, N.T., Aprea, I., Dougherty, G.W., Pennekamp, P., Kaiser, T., Mitchison, H.M., Hogg, C., Carr, S.B., Zariwala, M.A., Ferkol, T., Leigh, M.W., Davis, S.D., Atkinson, J., Dutcher, S.K., Knowles, M.R., Thiele, H., Altmüller, J., Krenz, H., Wöste, M., Brentrup, A., Ahrens, F., Vogelberg, C., Morris-Rosendahl, D.J. and Omran, H.
American Journal of Human Genetics 105
(5): 1030-1039.
7 November 2019
In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.
Wang, H., Georgakopoulou, A., Psatha, N., Li, C., Capsali, C., Samal, H.B., Anagnostopoulos, A., Ehrhardt, A., Izsvák, Z., Papayannopoulou, T., Yannaki, E. and Lieber, A.
Journal of Clinical Investigation 129
(2): 598-615.
1 February 2019
Long and repeat-rich intronic sequences favor circular RNA formation under conditions of reduced spliceosome activity.
Wang, M., Hou, J., Müller-McNicoll, M., Chen, W. and Schuman, E.M.
iScience 20
: 237-247.
25 October 2019
Increased retention of gadolinium in the inflamed brain after repeated administration of gadopentetate dimeglumine: a proof-of-concept study in mice combining ICP-MS and micro- and nano-SR-XRF.
Wang, S., Hesse, B., Roman, M., Stier, D., Castillo-Michel, H., Cotte, M., Suuronen, J.P., Lagrange, A., Radbruch, H., Paul, F., Taupitz, M., Schellenberger, E., Sack, I. and Infante-Duarte, C.
Investigative Radiology 54
(10): 617-626.
October 2019
Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus.
Wang, X., You, X., Langer, J.D., Hou, J., Rupprecht, F., Vlatkovic, I., Quedenau, C., Tushev, G., Epstein, I., Schaefke, B., Sun, W., Fang, L., Li, G., Hu, Y., Schuman, E.M. and Chen, W.
Nature Communications 10
(1): 5009.
1 November 2019
The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
Wanker, E.E., Ast, A., Schindler, F., Trepte, P. and Schnoegl, S.
Journal of Neurochemistry 151
(4): 507-519.
November 2019
The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats.
Warrington, J.P., Fan, F., Duncan, J., Cunningham, M.W., LaMarca, B.B., Dechend, R., Wallukat, G., Roman, R.J., Drummond, H.A., Granger, J.P. and Ryan, M.J.
Biology of Sex Differences 10
(1): 58.
11 December 2019
A novel allele for inducible Cre expression in germinal center B cells.
Weber, T., Seagal, J., Winkler, W., Wirtz, T., Chu, V.T. and Rajewsky, K.
European Journal of Immunology 49
(1): 192-194.
January 2019
Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer.
Weber-Lassalle, N., Borde, J., Weber-Lassalle, K., Horváth, J., Niederacher, D., Arnold, N., Kaulfuß, S., Ernst, C., Paul, V.G., Honisch, E., Klaschik, K., Volk, A.E., Kubisch, C., Rapp, S., Lichey, N., Altmüller, J., Lepkes, L., Pohl-Rescigno, E., Thiele, H., Nürnberg, P., Larsen, M., Richters, L., Rhiem, K., Wappenschmidt, B., Engel, C., Meindl, A., Schmutzler, R.K., Hahnen, E. and Hauke, J.
Breast Cancer Research 21
(1): 55.
29 April 2019
Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei, W., Hennig, B.P., Wang, J., Zhang, Y., Piazza, I., Pareja Sanchez, Y., Chabbert, C.D., Adjalley, S.H., Steinmetz, L.M. and Pelechano, V.
Genome Research 29
(12): 1974-1984.
December 2019
Spatially restricted stromal Wnt signaling restrains prostate epithelial progenitor growth through direct and indirect mechanisms.
Wei, X., Zhang, L., Zhou, Z., Kwon, O.J., Zhang, Y., Nguyen, H., Dumpit, R., True, L., Nelson, P., Dong, B., Xue, W., Birchmeier, W., Taketo, M.M., Xu, F., Creighton, C.J., Ittmann, M.M. and Xin, L.
Cell Stem Cell 24
(5): 753-768.
2 May 2019
Splicing factor Rbm10 facilitates heterochromatin assembly in fission yeast.
Weigt, M., Gao, Q., Ban, H., He, H., Mastrobuoni, G., Kempa, S., Chen, W. and Li, F.
bioRxiv
: 518936.
11 January 2019
Functional LGE imaging: cardiac phase-resolved assessment of focal fibrosis.
Weingartner, S., Demirel, O.B., Shenoy, C., Schad, L.R., Schulz-Menger, J. and Akcakaya, M.
In: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 23-27 Jul 2019, Berlin, Germany.
2019
3D organ models-Revolution in pharmacological research?
Weinhart, M., Hocke, A., Hippenstiel, S., Kurreck, J. and Hedtrich, S.
Pharmacological Research 139
: 446-451.
January 2019
Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.
Weller, J., Tzaridis, T., Mack, F., Steinbach, J.P., Schlegel, U., Hau, P., Krex, D., Grauer, O., Goldbrunner, R., Bähr, O., Uhl, M., Seidel, C., Tabatabai, G., Brehmer, S., Bullinger, L., Galldiks, N., Schaub, C., Kebir, S., Stummer, W., Simon, M., Fimmers, R., Coch, C., Glas, M., Herrlinger, U. and Schäfer, N.
Lancet Oncology 20
(10): 1444-1453.
October 2019
Global identification of functional microRNA-mRNA interactions in Drosophila.
Wessels, H.H., Lebedeva, S., Hirsekorn, A., Wurmus, R., Akalin, A., Mukherjee, N. and Ohler, U.
Nature Communications 10
(1): 1626.
9 April 2019
Distinct genetic alterations and luminal molecular subtype in nested variant of urothelial carcinoma (NVUC).
Weyerer, V., Weisser, R., Moskalev, E.A., Haller, F., Stoehr, R., Eckstein, M., Zinnall, U., Gaisa, N.T., Compérat, E., Perren, A., Keck, B., Allory, Y., Kristiansen, G., Wullich, B., Agaimy, A., Hartmann, A. and Bertz, S.
Histopathology 75
(6): 865-875.
December 2019
Neural mechanisms of perceptual decision-making and their link to neuropsychiatric symptoms in multiple sclerosis.
Weygandt, M., Behrens, J., Brasanac, J., Söder, E., Meyer-Arndt, L., Wakonig, K., Ritter, K., Brandt, A.U., Bellmann-Strobl, J., Gold, S.M., Haynes, J.D. and Paul, F.
Multiple Sclerosis and Related Disorders 33
: 139-145.
August 2019
Interactions between neural decision-making circuits predict long-term dietary treatment success in obesity.
Weygandt, M., Spranger, J., Leupelt, V., Maurer, L., Bobbert, T., Mai, K. and Haynes, J.D.
NeuroImage 184
: 520-534.
1 January 2019
The role of sodium in modulating immune cell function.
Wilck, N., Balogh, A., Markó, L., Bartolomaeus, H. and Müller, D.N.
Nature Reviews Nephrology 15
(9): 546-558.
September 2019
Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis.
Wild, P., Susperregui, A., Piazza, I., Dörig, C., Oke, A., Arter, M., Yamaguchi, M., Hilditch, A.T., Vuina, K., Chan, K.C., Gromova, T., Haber, J.E., Fung, J.C., Picotti, P. and Matos, J.
Molecular Cell 75
(4): 859-874.
22 August 2019
High salt inhibits tumor growth by enhancing anti-tumor immunity.
Willebrand, R., Hamad, I., Van Zeebroeck, L., Kiss, M., Bruderek, K., Geuzens, A., Swinnen, D., Côrte-Real, B.F., Markó, L., Lebegge, E., Laoui, D., Kemna, J., Kammertoens, T., Brandau, S., Van Ginderachter, J.A. and Kleinewietfeld, M.
Frontiers in Immunology 10
: 1141.
4 June 2019
4D flow imaging with 2D-selective excitation.
Wink, C., Ferrazzi, G., Bassenge, J.P., Flassbeck, S., Schmidt, S., Schaeffter, T. and Schmitter, S.
Magnetic Resonance in Medicine 82
(3): 886-900.
September 2019
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.
Wirbel, J., Pyl, P.T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J.S., Voigt, A.Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L.P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A.M., Manghi, P., Gandini, S., Serrano, D., Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Waldron, L., Naccarati, A., Segata, N., Sinha, R., Ulrich, C.M., Brenner, H., Arumugam, M., Bork, P. and Zeller, G.
Nature Medicine 25
(4): 679-689.
April 2019
Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial.
Wirth, M., Schwarz, C., Benson, G., Horn, N., Buchert, R., Lange, C., Köbe, T., Hetzer, S., Maglione, M., Michael, E., Märschenz, S., Mai, K., Kopp, U., Schmitz, D., Grittner, U., Sigrist, S.J., Stekovic, S., Madeo, F. and Flöel, A.
Alzheimer's Research & Therapy 11
(1): 36.
1 May 2019
Insulin-like growth factor binding protein 2 (IGFBP-2) and the risk of developing type 2 diabetes.
Wittenbecher, C., Ouni, M., Kuxhaus, O., Jähnert, M., Gottmann, P., Teichmann, A., Meidtner, K., Kriebel, J., Grallert, H., Pischon, T., Boeing, H., Schulze, M.B. and Schürmann, A.
Diabetes 68
(1): 188-197.
1 January 2019
Retroperitoneal hematoma after bone marrow biopsy: the first cut should not be the deepest.
Wojciechowski, A., Duckert, M., Hartmann, J., Bullinger, L. and Matzdorff, A.
Oncology Research and Treatment 42
(5): 283-288.
May 2019
PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells.
Wolf, F.A., Hamey, F.K., Plass, M., Solana, J., Dahlin, J.S., Göttgens, B., Rajewsky, N., Simon, L. and Theis, F.J.
Genome Biology 20
(1): 59.
19 March 2019
CRISPR-activation-based screen reveals neuronal fate promotion by polycomb repressive complex 2 during direct reprogramming.
Wolfram, T. and Tursun, B.
Stem Cell Investigation 6
: 32.
September 2019
Muscle wasting and function after muscle activation and early protocol-based physiotherapy: an explorative trial.
Wollersheim, T., Grunow, J.J., Carbon, N.M., Haas, K., Malleike, J., Ramme, S.F., Schneider, J., Spies, C.D., Märdian, S., Mai, K., Spuler, S., Fielitz, J. and Weber-Carstens, S.
Journal of Cachexia Sarcopenia and Muscle 10
(4): 734-747.
August 2019
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Wong, J.B., Hewitt, S.L., Heltemes-Harris, L.M., Mandal, M., Johnson, K., Rajewsky, K., Koralov, S.B., Clark, M.R., Farrar, M.A. and Skok, J.A.
Nature Communications 10
(1): 4768.
18 October 2019
The cell adhesion protein CAR is a negative regulator of synaptic transmission.
Wrackmeyer, U., Kaldrack, J., Jüttner, R., Pannasch, U., Gimber, N., Freiberg, F., Purfürst, B., Kainmueller, D., Schmitz, D., Haucke, V., Rathjen, F.G. and Gotthardt, M.
Scientific Reports 9
(1): 6768.
1 May 2019
HOT or not: examining the basis of high-occupancy target regions.
Wreczycka, K., Franke, V., Uyar, B., Wurmus, R., Bulut, S., Tursun, B. and Akalin, A.
Nucleic Acids Research
: gkz460.
20 June 2019
Clinical relevance of semaphorin-3F in patients with prostate cancer.
Wu, G.
Clinical and Investigative Medicine 42
(3): E64-E69.
29 September 2019
Dosis und Wirkung in der Toxikologie: die Haber'sche Regel und Ableitungen.
Wunderlich, V.
BIOspektrum 25
(5): 584-585.
September 2019
Die Kenntnis der Krebskrankheit aus historischer Perspektive: Das beispiellose Werk des Berliner Arztes Jacob Wolff (1861–1938).
Wunderlich, V.
Acta Historica Leopoldina 74
: 221-247.
2019
Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program.
Wyler, E., Franke, V., Menegatti, J., Kocks, C., Boltengagen, A., Praktiknjo, S., Walch-Rückheim, B., Bosse, J., Rajewsky, N., Grässer, F., Akalin, A. and Landthaler, M.
Nature Communications 10
(1): 4878.
25 October 2019
Y
Systemic outcomes of (Pyr(1))-apelin-13 infusion at mid-late pregnancy in a rat model with preeclamptic features.
Yamaleyeva, L.M., Brosnihan, K.B., Elsangeedy, E., McGee, C., Shi, S., Caudell, D., Miller, C., Varagic, J., Bader, M., Dechend, R. and Shaltout, H.A.
Scientific Reports 9
(1): 8579.
12 June 2019
(In situ) conformational changes of the Escherichia coli serine chemoreceptor in different signaling states.
Yang, W., Cassidy, C.K., Ames, P., Diebolder, C.A., Schulten, K., Luthey-Schulten, Z., Parkinson, J.S. and Briegel, A.
mBio 10
(4): e00973.
2 July 2019
Epigenetic co-deregulation of EZH2/TET1 is a senescence-countering, actionable vulnerability in triple-negative breast cancer.
Yu, Y., Qi, J., Xiong, J., Jiang, L., Cui, D., He, J., Chen, P., Li, L., Wu, C., Ma, T., Shao, S., Wang, J., Yu, D., Zhou, B., Huang, D., Schmitt, C.A. and Tao, R.
Theranostics 9
(3): 761-777.
24 January 2019
Efficient gene editing of human induced pluripotent stem cells using CRISPR/Cas9.
Yumlu, S., Bashir, S., Stumm, J. and Kühn, R.
Methods in Molecular Biology 1961
: 137-151.
2019
Z
One-pot synthesis of poly(glycerol-co-succinic acid) nanogels for dermal delivery.
Zabihi, F., Koeppe, H., Achazi, K., Hedtrich, S. and Haag, R.
Biomacromolecules 20
(5): 1867-1875.
13 May 2019
Integrated phosphoproteome and transcriptome analysis reveals Chlamydia-induced epithelial-to-mesenchymal transition in host cells.
Zadora, P.K., Chumduri, C., Imami, K., Berger, H., Mi, Y., Selbach, M., Meyer, T.F. and Gurumurthy, R.K.
Cell Reports 26
(5): 1286-1302.
29 January 2019
Non-invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: the DACHS study.
Zaimenko, I., Jaeger, C., Brenner, H., Chang-Claude, J., Hoffmeister, M., Grötzinger, C., Detjen, K., Burock, S., Schmitt, C.A., Stein, U. and Lisec, J.
International Journal of Cancer 145
(1): 221-231.
1 July 2019
Quantification in cardiovascular magnetic resonance: agreement of software from three different vendors on assessment of left ventricular function, 2D flow and parametric mapping.
Zange, L., Muehlberg, F., Blaszczyk, E., Schwenke, S., Traber, J., Funk, S. and Schulz-Menger, J.
Journal of Cardiovascular Magnetic Resonance 21
(1): 12.
21 February 2019
Increased ethanol consumption and locomotion develop upon ethanol deprivation in rats overexpressing the adenosine A(2A) receptor.
Zaniewska, M., Gawliński, D., Wyczesana, M., Nowak, E., Kula, K., Maciów-Głąb, M., Jastrzębska, J., Sadakierska-Chudy, A., Bader, M. and Fuxe, K.
Neuroscience 418
: 133-148.
15 October 2019
TMT labeling for the masses: a robust and cost-efficient, in-solution labeling approach.
Zecha, J., Satpathy, S., Kanashova, T., Avanessian, S.C., Kane, M.H., Clauser, K.R., Mertins, P., Carr, S.A. and Kuster, B.
Molecular & Cellular Proteomics 18
(7): 1468-1478.
1 July 2019
Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex.
Zhang, G., Kruse, T., Guasch Boldú, C., Garvanska, D.H., Coscia, F., Mann, M., Barisic, M. and Nilsson, J.
EMBO Journal 38
(7): e100977.
1 April 2019
Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence.
Zhang, H., Alsaleh, G., Feltham, J., Sun, Y., Napolitano, G., Riffelmacher, T., Charles, P., Frau, L., Hublitz, P., Yu, Z., Mohammed, S., Ballabio, A., Balabanov, S., Mellor, J. and Simon, A.K.
Molecular Cell 76
(1): 110-125.
3 October 2019
Rapid synthesis of γ-halide/pseudohalide-substituted cyanine sensors with programmed generation of singlet oxygen.
Zhang, Q., Xu, S., Lai, F., Wang, Y., Zhang, N., Nazare, M. and Hu, H.Y.
Organic Letters 21
(7): 2121-2125.
5 April 2019
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations.
Zhao, W., Bohleber, S., Schmidt, H., Seeher, S., Howard, M.T., Braun, D., Arndt, S., Reuter, U., Wende, H., Birchmeier, C., Fradejas-Villar, N. and Schweizer, U.
Journal of Biological Chemistry 294
(39): 14185-14200.
27 September 2019
Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
Zhao, X., Nedvetsky, P., Stanchi, F., Vion, A.C., Popp, O., Zühlke, K., Dittmar, G., Klussmann, E. and Gerhardt, H.
eLife 8
: e46380.
3 October 2019
Delayed allogeneic skin graft rejection in CD26-deficient mice.
Zhao, X., Zhang, K., Daniel, P., Wisbrun, N., Fuchs, H. and Fan, H.
Cellular and Molecular Immunology 16
(6): 557-567.
June 2019
A novel predictor tool of biochemical recurrence after radical prostatectomy based on a five-microRNA tissue signature.
Zhao, Z., Weickmann, S., Jung, M., Lein, M., Kilic, E., Stephan, C., Erbersdobler, A., Fendler, A. and Jung, K.
Cancers 11
(10): 1603.
21 October 2019
The KCNE2 potassium channel β subunit is required for normal lung function and resilience to ischemia and reperfusion injury.
Zhou, L., Köhncke, C., Hu, Z., Roepke, T.K. and Abbott, G.W.
FASEB Journal 33
(9): 9762-9774.
September 2019
The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer.
Zhu, Q., Fang, L., Heuberger, J., Kranz, A., Schipper, J., Scheckenbach, K., Oliveira Vidal, R., Sunaga-Franze, D.Y., Müller, M., Wulf-Goldenberg, A., Sauer, S. and Birchmeier, W.
Cell Reports 26
(2): 415-428.
8 January 2019
Hyponatriämie in Notfall- und Intensivmedizin [Hyponatremia in emergency and critical care medicine].
Zickler, D. and Schmidt-Ott, K.M.
Nephrologe 14
(6): 422-430.
November 2019
The importance of developing therapies targeting the biological spectrum of metastatic disease.
Zijlstra, A., Von Lersner, A., Yu, D., Borrello, L., Oudin, M., Kang, Y., Sahai, E., Fingleton, B., Stein, U., Cox, T.R., Price, J.T., Kato, Y., Welm, A.L. and Aguirre-Ghiso, J.A.
Clinical and Experimental Metastasis 36
(4): 305-309.
August 2019
Ç
Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies.
Çakmak-Görür, N., Radke, J., Rhein, S., Schumann, E., Willimsky, G., Heppner, F.L., Blankenstein, T. and Pezzutto, A.
Leukemia 33
(4): 1039-1043.
April 2019
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